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Pineal Gland Glial Cyst

MedGen UID:
235477
•Concept ID:
C1335413
•
Finding
Synonyms: Benign Glial Cyst of Pineal Gland; Benign Glial Cyst of the Pineal Gland; Benign Pineal Glial Cyst; Glial Cyst of Pineal Gland; Glial Cyst of the Pineal Gland; Pineal Glial Cyst

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPineal Gland Glial Cyst

Professional guidelines

PubMed

Diagnosis and management challenge of a granular cell astrocytoma of the pineal region: case report.
El Asri AC, Baallal H, Zoubeir Y, Sinaa M, Albouzidi A, Gazzaz M, Akhaddar A, Boucetta M, El Mostarchid B
J Neurosurg Pediatr 2015 May;15(5):506-9. Epub 2015 Feb 20 doi: 10.3171/2014.10.PEDS13388. PMID: 25700123
Is CRX protein a useful marker in differential diagnosis of tumors of the pineal region?
Manila A, Mariangela N, Libero L, Francesca G, Romana BF, Felice G
Pediatr Dev Pathol 2014 Mar-Apr;17(2):85-8. Epub 2014 Feb 20 doi: 10.2350/13-06-1346-OA.1. PMID: 24555912
Stereotactic diagnosis and treatment of pineal region tumours and vascular malformations.
Dempsey PK, Kondziolka D, Lunsford LD
Acta Neurochir (Wien) 1992;116(1):14-22. doi: 10.1007/BF01541248. PMID: 1615765

Recent clinical studies

Etiology

Rosette-Forming Glioneuronal Tumor in the Pineal Region: A Series of 6 Cases and Literature Review.
Lin CC, Mansukhani MM, Bruce JN, Canoll P, Zanazzi G
J Neuropathol Exp Neurol 2021 Oct 26;80(10):933-943. doi: 10.1093/jnen/nlab089. PMID: 34498065
Pathologic Prognostic Factors of Pineal Parenchymal Tumor of Intermediate Differentiation.
Chatterjee D, Lath K, Singla N, Kumar N, Radotra BD
Appl Immunohistochem Mol Morphol 2019 Mar;27(3):210-215. doi: 10.1097/PAI.0000000000000565. PMID: 28800009
Central nervous system.
Adamson DC, Rasheed BA, McLendon RE, Bigner DD
Cancer Biomark 2010;9(1-6):193-210. doi: 10.3233/CBM-2011-0177. PMID: 22112477
Nonneoplastic pineal cysts: a clinicopathologic study of twenty-one cases.
Mena H, Armonda RA, Ribas JL, Ondra SL, Rushing EJ
Ann Diagn Pathol 1997 Oct;1(1):11-8. doi: 10.1016/s1092-9134(97)80004-4. PMID: 9869821
Pineal region tumors.
Portillo ML, de González CM, Sangines JB, Zapata GS
Int Surg 1982 Oct-Dec;67(4):329-33. PMID: 7160992

Diagnosis

Benign and Malignant Tumors of the Pineal Region.
Upadhyayula PS, Neira JA, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:153-173. doi: 10.1007/978-3-031-23705-8_6. PMID: 37452938
Pathologic Prognostic Factors of Pineal Parenchymal Tumor of Intermediate Differentiation.
Chatterjee D, Lath K, Singla N, Kumar N, Radotra BD
Appl Immunohistochem Mol Morphol 2019 Mar;27(3):210-215. doi: 10.1097/PAI.0000000000000565. PMID: 28800009
Papillary tumour of the pineal region.
Poulgrain K, Gurgo R, Winter C, Ong B, Lau Q
J Clin Neurosci 2011 Aug;18(8):1007-17. Epub 2011 Jun 11 doi: 10.1016/j.jocn.2010.12.027. PMID: 21658955
Central nervous system.
Adamson DC, Rasheed BA, McLendon RE, Bigner DD
Cancer Biomark 2010;9(1-6):193-210. doi: 10.3233/CBM-2011-0177. PMID: 22112477
Pineal region tumors of childhood.
Packer RJ, Sutton LN, Rosenstock JG, Rorke LB, Bilaniuk LT, Zimmerman RA, Littman PA, Bruce DA, Schut L
Pediatrics 1984 Jul;74(1):97-102. PMID: 6739222

Therapy

Second primary brain tumors following cranial irradiation for pediatric solid brain tumors.
You SH, Lyu CJ, Kim DS, Suh CO
Childs Nerv Syst 2013 Oct;29(10):1865-70. Epub 2013 Apr 10 doi: 10.1007/s00381-013-2098-4. PMID: 23571774
Asymptomatic and symptomatic glial cysts of the pineal gland.
Taraszewska A, Matyja E, Koszewski W, Zaczyński A, Bardadin K, Czernicki Z
Folia Neuropathol 2008;46(3):186-95. PMID: 18825594
Pineal region tumors of childhood.
Packer RJ, Sutton LN, Rosenstock JG, Rorke LB, Bilaniuk LT, Zimmerman RA, Littman PA, Bruce DA, Schut L
Pediatrics 1984 Jul;74(1):97-102. PMID: 6739222

Prognosis

Pathologic Prognostic Factors of Pineal Parenchymal Tumor of Intermediate Differentiation.
Chatterjee D, Lath K, Singla N, Kumar N, Radotra BD
Appl Immunohistochem Mol Morphol 2019 Mar;27(3):210-215. doi: 10.1097/PAI.0000000000000565. PMID: 28800009
Increased mitotic and proliferative activity are associated with worse prognosis in papillary tumors of the pineal region.
Heim S, Beschorner R, Mittelbronn M, Keyvani K, Riemenschneider MJ, Vajtai I, Hartmann C, Acker T, Blümcke I, Paulus W, Hasselblatt M
Am J Surg Pathol 2014 Jan;38(1):106-10. doi: 10.1097/PAS.0b013e31829e492d. PMID: 24121176
Papillary tumour of the pineal region.
Poulgrain K, Gurgo R, Winter C, Ong B, Lau Q
J Clin Neurosci 2011 Aug;18(8):1007-17. Epub 2011 Jun 11 doi: 10.1016/j.jocn.2010.12.027. PMID: 21658955
Central nervous system.
Adamson DC, Rasheed BA, McLendon RE, Bigner DD
Cancer Biomark 2010;9(1-6):193-210. doi: 10.3233/CBM-2011-0177. PMID: 22112477
Pineal parenchymal tumors: a correlation of histological features with prognosis in 66 cases.
Jouvet A, Saint-Pierre G, Fauchon F, Privat K, Bouffet E, Ruchoux MM, Chauveinc L, Fèvre-Montange M
Brain Pathol 2000 Jan;10(1):49-60. doi: 10.1111/j.1750-3639.2000.tb00242.x. PMID: 10668895Free PMC Article

Clinical prediction guides

Pathologic Prognostic Factors of Pineal Parenchymal Tumor of Intermediate Differentiation.
Chatterjee D, Lath K, Singla N, Kumar N, Radotra BD
Appl Immunohistochem Mol Morphol 2019 Mar;27(3):210-215. doi: 10.1097/PAI.0000000000000565. PMID: 28800009
Radical resection of nongerminomatous pineal region tumors via the occipital transtentorial approach based on arachnoidal consideration: experience on a series of 143 patients.
Qi S, Fan J, Zhang XA, Zhang H, Qiu B, Fang L
Acta Neurochir (Wien) 2014 Dec;156(12):2253-62. Epub 2014 Sep 23 doi: 10.1007/s00701-014-2224-4. PMID: 25246142
Contribution of the daily melatonin profile to diagnosis of tumors of the pineal region.
Leston J, Mottolese C, Champier J, Jouvet A, Brun J, Sindou M, Chazot G, Claustrat B, Fèvre-Montange M
J Neurooncol 2009 Jul;93(3):387-94. Epub 2009 Jan 25 doi: 10.1007/s11060-008-9792-1. PMID: 19169855
Immunohistochemical localization of human pineal tissue antigens in normal retina and retinoblastomas.
Sawai J, Nakazato Y, Yamane Y, Kimura N, Kishi S
Neuropathology 2003 Jun;23(2):119-28. doi: 10.1046/j.1440-1789.2003.00488.x. PMID: 12777100
Pineal region tumors.
Portillo ML, de González CM, Sangines JB, Zapata GS
Int Surg 1982 Oct-Dec;67(4):329-33. PMID: 7160992

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