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Entrapment neuropathy

MedGen UID:
266933
•Concept ID:
C1510429
•
Disease or Syndrome
Synonym: Nerve compression syndrome
SNOMED CT: Peripheral nerve entrapment syndrome (45781009); Compression neuropathy (45781009); Nerve entrapment syndrome (45781009); Trapped nerve (45781009); Entrapment neuropathy (45781009)
 
HPO: HP:0012181
Monarch Initiative: MONDO:0003615

Definition

Malfunction of a peripheral nerve resulting from mechanical compression of the nerve roots from internal or external causes and leading to a conduction block or axonal loss. [from HPO]

Professional guidelines

PubMed

Carpal Tunnel Syndrome: Diagnosis and Management.
Wipperman J, Goerl K
Am Fam Physician 2016 Dec 15;94(12):993-999. PMID: 28075090
Treatment for ulnar neuropathy at the elbow.
Caliandro P, La Torre G, Padua R, Giannini F, Padua L
Cochrane Database Syst Rev 2016 Nov 15;11(11):CD006839. doi: 10.1002/14651858.CD006839.pub4. PMID: 27845501Free PMC Article
Peroneal Nerve Palsy: Evaluation and Management.
Poage C, Roth C, Scott B
J Am Acad Orthop Surg 2016 Jan;24(1):1-10. doi: 10.5435/JAAOS-D-14-00420. PMID: 26700629

Recent clinical studies

Etiology

Carpal tunnel syndrome.
Harinesan N, Silsby M, Simon NG
Handb Clin Neurol 2024;201:61-88. doi: 10.1016/B978-0-323-90108-6.00005-3. PMID: 38697747
Ganglia-Induced Tarsal Tunnel Syndrome.
Koketsu K, Kim K, Tajiri T, Isu T, Morimoto D, Kokubo R, Dan H, Morita A
J Nippon Med Sch 2024;91(1):114-118. doi: 10.1272/jnms.JNMS.2024_91-203. PMID: 38462440
Effectiveness of focused extracorporeal shock wave therapy in the treatment of carpal tunnel syndrome : A randomized, placebo-controlled pilot study.
Gesslbauer C, Mickel M, Schuhfried O, Huber D, Keilani M, Crevenna R
Wien Klin Wochenschr 2021 Jun;133(11-12):568-577. Epub 2020 Dec 22 doi: 10.1007/s00508-020-01785-9. PMID: 33351153Free PMC Article
Treatment for ulnar neuropathy at the elbow.
Caliandro P, La Torre G, Padua R, Giannini F, Padua L
Cochrane Database Syst Rev 2016 Nov 15;11(11):CD006839. doi: 10.1002/14651858.CD006839.pub4. PMID: 27845501Free PMC Article
Diabetic neuropathy.
Bansal V, Kalita J, Misra UK
Postgrad Med J 2006 Feb;82(964):95-100. doi: 10.1136/pgmj.2005.036137. PMID: 16461471Free PMC Article

Diagnosis

Carpal tunnel syndrome.
Harinesan N, Silsby M, Simon NG
Handb Clin Neurol 2024;201:61-88. doi: 10.1016/B978-0-323-90108-6.00005-3. PMID: 38697747
Carpal tunnel syndrome: updated evidence and new questions.
Padua L, Cuccagna C, Giovannini S, Coraci D, Pelosi L, Loreti C, Bernabei R, Hobson-Webb LD
Lancet Neurol 2023 Mar;22(3):255-267. Epub 2022 Dec 13 doi: 10.1016/S1474-4422(22)00432-X. PMID: 36525982
Carpal tunnel syndrome: state-of-the-art review.
Osiak K, Elnazir P, Walocha JA, Pasternak A
Folia Morphol (Warsz) 2022;81(4):851-862. Epub 2021 Nov 16 doi: 10.5603/FM.a2021.0121. PMID: 34783004
Carpal tunnel sonography.
Gervasio A, Stelitano C, Bollani P, Giardini A, Vanzetti E, Ferrari M
J Ultrasound 2020 Sep;23(3):337-347. Epub 2020 Apr 22 doi: 10.1007/s40477-020-00460-z. PMID: 32323256Free PMC Article
Carpal Tunnel Syndrome: Diagnosis and Management.
Wipperman J, Goerl K
Am Fam Physician 2016 Dec 15;94(12):993-999. PMID: 28075090

Therapy

Acroparesthesias: An Overview.
Slouma M, Ben Dhia S, Cheour E, Gharsallah I
Curr Rheumatol Rev 2024;20(2):115-126. doi: 10.2174/0115733971254976230927113202. PMID: 37921132
Effectiveness of focused extracorporeal shock wave therapy in the treatment of carpal tunnel syndrome : A randomized, placebo-controlled pilot study.
Gesslbauer C, Mickel M, Schuhfried O, Huber D, Keilani M, Crevenna R
Wien Klin Wochenschr 2021 Jun;133(11-12):568-577. Epub 2020 Dec 22 doi: 10.1007/s00508-020-01785-9. PMID: 33351153Free PMC Article
Rewiring the primary somatosensory cortex in carpal tunnel syndrome with acupuncture.
Maeda Y, Kim H, Kettner N, Kim J, Cina S, Malatesta C, Gerber J, McManus C, Ong-Sutherland R, Mezzacappa P, Libby A, Mawla I, Morse LR, Kaptchuk TJ, Audette J, Napadow V
Brain 2017 Apr 1;140(4):914-927. doi: 10.1093/brain/awx015. PMID: 28334999Free PMC Article
Carpal Tunnel Syndrome: Diagnosis and Management.
Wipperman J, Goerl K
Am Fam Physician 2016 Dec 15;94(12):993-999. PMID: 28075090
Treatment for ulnar neuropathy at the elbow.
Caliandro P, La Torre G, Padua R, Giannini F, Padua L
Cochrane Database Syst Rev 2016 Nov 15;11(11):CD006839. doi: 10.1002/14651858.CD006839.pub4. PMID: 27845501Free PMC Article

Prognosis

Carpal tunnel sonography.
Gervasio A, Stelitano C, Bollani P, Giardini A, Vanzetti E, Ferrari M
J Ultrasound 2020 Sep;23(3):337-347. Epub 2020 Apr 22 doi: 10.1007/s40477-020-00460-z. PMID: 32323256Free PMC Article
Rewiring the primary somatosensory cortex in carpal tunnel syndrome with acupuncture.
Maeda Y, Kim H, Kettner N, Kim J, Cina S, Malatesta C, Gerber J, McManus C, Ong-Sutherland R, Mezzacappa P, Libby A, Mawla I, Morse LR, Kaptchuk TJ, Audette J, Napadow V
Brain 2017 Apr 1;140(4):914-927. doi: 10.1093/brain/awx015. PMID: 28334999Free PMC Article
Carpal Tunnel Syndrome: Diagnosis and Management.
Wipperman J, Goerl K
Am Fam Physician 2016 Dec 15;94(12):993-999. PMID: 28075090
Peroneal Nerve Palsy: Evaluation and Management.
Poage C, Roth C, Scott B
J Am Acad Orthop Surg 2016 Jan;24(1):1-10. doi: 10.5435/JAAOS-D-14-00420. PMID: 26700629
Nerve entrapment syndromes.
Nakano KK
Curr Opin Rheumatol 1997 Mar;9(2):165-73. doi: 10.1097/00002281-199703000-00015. PMID: 9135923

Clinical prediction guides

Carpal tunnel syndrome: state-of-the-art review.
Osiak K, Elnazir P, Walocha JA, Pasternak A
Folia Morphol (Warsz) 2022;81(4):851-862. Epub 2021 Nov 16 doi: 10.5603/FM.a2021.0121. PMID: 34783004
Effectiveness of focused extracorporeal shock wave therapy in the treatment of carpal tunnel syndrome : A randomized, placebo-controlled pilot study.
Gesslbauer C, Mickel M, Schuhfried O, Huber D, Keilani M, Crevenna R
Wien Klin Wochenschr 2021 Jun;133(11-12):568-577. Epub 2020 Dec 22 doi: 10.1007/s00508-020-01785-9. PMID: 33351153Free PMC Article
Management of Atraumatic Posterior Interosseous Nerve Palsy.
Sigamoney KV, Rashid A, Ng CY
J Hand Surg Am 2017 Oct;42(10):826-830. doi: 10.1016/j.jhsa.2017.07.026. PMID: 28969808
Rewiring the primary somatosensory cortex in carpal tunnel syndrome with acupuncture.
Maeda Y, Kim H, Kettner N, Kim J, Cina S, Malatesta C, Gerber J, McManus C, Ong-Sutherland R, Mezzacappa P, Libby A, Mawla I, Morse LR, Kaptchuk TJ, Audette J, Napadow V
Brain 2017 Apr 1;140(4):914-927. doi: 10.1093/brain/awx015. PMID: 28334999Free PMC Article
Thoracic outlet syndrome.
Huang JH, Zager EL
Neurosurgery 2004 Oct;55(4):897-902; discussion 902-3. doi: 10.1227/01.neu.0000137333.04342.4d. PMID: 15458598

Recent systematic reviews

Hand and Wrist Injuries Associated With Application of Physical Restraints: A Systematic Review.
Khan S, Mosa A, Clayton A, McCabe S
Hand (N Y) 2023 Nov;18(8):1253-1257. Epub 2022 Jul 1 doi: 10.1177/15589447221105548. PMID: 35778878Free PMC Article
Ulnar nerve entrapment at the elbow. A surgical series and a systematic review of the literature.
Lauretti L, D'Alessandris QG, De Simone C, Legninda Sop FY, Remore LM, Izzo A, Fernandez E
J Clin Neurosci 2017 Dec;46:99-108. Epub 2017 Sep 8 doi: 10.1016/j.jocn.2017.08.012. PMID: 28890032
Treatment for ulnar neuropathy at the elbow.
Caliandro P, La Torre G, Padua R, Giannini F, Padua L
Cochrane Database Syst Rev 2016 Nov 15;11(11):CD006839. doi: 10.1002/14651858.CD006839.pub4. PMID: 27845501Free PMC Article
Treatment for ulnar neuropathy at the elbow.
Caliandro P, La Torre G, Padua R, Giannini F, Padua L
Cochrane Database Syst Rev 2012 Jul 11;(7):CD006839. doi: 10.1002/14651858.CD006839.pub3. PMID: 22786500
Treatment for ulnar neuropathy at the elbow.
Caliandro P, La Torre G, Padua R, Giannini F, Padua L
Cochrane Database Syst Rev 2011 Feb 16;(2):CD006839. doi: 10.1002/14651858.CD006839.pub2. PMID: 21328287

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