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Acantholytic variant squamous cell breast carcinoma

MedGen UID:
274268
•Concept ID:
C1519485
•
Neoplastic Process
Synonyms: acantholytic variant squamous cell breast carcinoma; Breast Squamous Cell Carcinoma, Acantholytic Variant; Squamous Cell Breast Carcinoma, Acantholytic Variant; squamous cell breast carcinoma, acantholytic variant
 
Monarch Initiative: MONDO:0004229

Definition

A squamous cell carcinoma that arises from the breast parenchyma and is characterized by cellular discohesion resulting in a pseudoangiosarcomatous pattern. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAcantholytic variant squamous cell breast carcinoma

Recent clinical studies

Etiology

Cervical Squamous Carcinomas With Prominent Acantholysis and Areas Resembling Breast Lobular Carcinoma: An Aggressive Form of Dedifferentation.
Scott K, Bryson G, Jamison J, Coutts M, McCluggage WG
Int J Gynecol Pathol 2018 Jan;37(1):74-81. doi: 10.1097/PGP.0000000000000387. PMID: 28700422

Diagnosis

Cervical Squamous Carcinomas With Prominent Acantholysis and Areas Resembling Breast Lobular Carcinoma: An Aggressive Form of Dedifferentation.
Scott K, Bryson G, Jamison J, Coutts M, McCluggage WG
Int J Gynecol Pathol 2018 Jan;37(1):74-81. doi: 10.1097/PGP.0000000000000387. PMID: 28700422
Acantholytic variant of squamous cell carcinoma of the breast: a case report.
Parramore B, Hanly M, Yeh KA, McNeely T
Am Surg 1999 May;65(5):467-9. PMID: 10231220
Pseudoangiosarcomatous carcinoma: a clinicopathological study of seven cases.
Banerjee SS, Eyden BP, Wells S, McWilliam LJ, Harris M
Histopathology 1992 Jul;21(1):13-23. doi: 10.1111/j.1365-2559.1992.tb00338.x. PMID: 1634198
Acantholytic variant of squamous-cell carcinoma of the breast.
Eusebi V, Lamovec J, Cattani MG, Fedeli F, Millis RR
Am J Surg Pathol 1986 Dec;10(12):855-61. doi: 10.1097/00000478-198612000-00004. PMID: 2431630

Prognosis

Cervical Squamous Carcinomas With Prominent Acantholysis and Areas Resembling Breast Lobular Carcinoma: An Aggressive Form of Dedifferentation.
Scott K, Bryson G, Jamison J, Coutts M, McCluggage WG
Int J Gynecol Pathol 2018 Jan;37(1):74-81. doi: 10.1097/PGP.0000000000000387. PMID: 28700422
Acantholytic variant of squamous cell carcinoma of the breast: a case report.
Parramore B, Hanly M, Yeh KA, McNeely T
Am Surg 1999 May;65(5):467-9. PMID: 10231220
Pseudoangiosarcomatous carcinoma: a clinicopathological study of seven cases.
Banerjee SS, Eyden BP, Wells S, McWilliam LJ, Harris M
Histopathology 1992 Jul;21(1):13-23. doi: 10.1111/j.1365-2559.1992.tb00338.x. PMID: 1634198
Acantholytic variant of squamous-cell carcinoma of the breast.
Eusebi V, Lamovec J, Cattani MG, Fedeli F, Millis RR
Am J Surg Pathol 1986 Dec;10(12):855-61. doi: 10.1097/00000478-198612000-00004. PMID: 2431630

Clinical prediction guides

Immunohistochemical and cytogenetic characterization of acantholytic squamous cell carcinoma of the breast.
Aulmann S, Schnabel PA, Helmchen B, Dienemann H, Drings P, Otto HF, Sinn HP
Virchows Arch 2005 Mar;446(3):305-9. Epub 2005 Jan 25 doi: 10.1007/s00428-004-1163-5. PMID: 15668805

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