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Adult Malignant Brain Neoplasm

MedGen UID:
277326
•Concept ID:
C1334557
•
Neoplastic Process
Synonyms: Brain Neoplasms, Adult, Malignant; Malignant Adult Brain Tumor; Malignant Tumor of Adult Brain; Malignant Tumor of the Adult Brain

Definition

A malignant brain neoplasm occurring in adults. [from NCI]

Professional guidelines

PubMed

Ependymoma: Evaluation and Management Updates.
Rudà R, Bruno F, Pellerino A, Soffietti R
Curr Oncol Rep 2022 Aug;24(8):985-993. Epub 2022 Apr 6 doi: 10.1007/s11912-022-01260-w. PMID: 35384591Free PMC Article
Glioblastoma: Overview of Disease and Treatment.
Davis ME
Clin J Oncol Nurs 2016 Oct 1;20(5 Suppl):S2-8. doi: 10.1188/16.CJON.S1.2-8. PMID: 27668386Free PMC Article
Diagnosis and treatment of hyperprolactinemia: an Endocrine Society clinical practice guideline.
Melmed S, Casanueva FF, Hoffman AR, Kleinberg DL, Montori VM, Schlechte JA, Wass JA; Endocrine Society
J Clin Endocrinol Metab 2011 Feb;96(2):273-88. doi: 10.1210/jc.2010-1692. PMID: 21296991

Recent clinical studies

Etiology

Brain Tumors in Adolescents and Young Adults: A Review.
Rousseau J, Bennett J, Lim-Fat MJ
Semin Neurol 2023 Dec;43(6):909-928. Epub 2023 Nov 10 doi: 10.1055/s-0043-1776775. PMID: 37949116
Benign Glioma.
Wu PB, Filley AC, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:31-71. doi: 10.1007/978-3-031-23705-8_2. PMID: 37452934
Risk factors for childhood and adult primary brain tumors.
Ostrom QT, Adel Fahmideh M, Cote DJ, Muskens IS, Schraw JM, Scheurer ME, Bondy ML
Neuro Oncol 2019 Nov 4;21(11):1357-1375. doi: 10.1093/neuonc/noz123. PMID: 31301133Free PMC Article
Central nervous system gliomas.
Reni M, Mazza E, Zanon S, Gatta G, Vecht CJ
Crit Rev Oncol Hematol 2017 May;113:213-234. Epub 2017 Mar 22 doi: 10.1016/j.critrevonc.2017.03.021. PMID: 28427510
Glioblastoma: Overview of Disease and Treatment.
Davis ME
Clin J Oncol Nurs 2016 Oct 1;20(5 Suppl):S2-8. doi: 10.1188/16.CJON.S1.2-8. PMID: 27668386Free PMC Article

Diagnosis

Benign Glioma.
Wu PB, Filley AC, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:31-71. doi: 10.1007/978-3-031-23705-8_2. PMID: 37452934
Contemporary management of high-grade gliomas.
Sim HW, Morgan ER, Mason WP
CNS Oncol 2018 Jan;7(1):51-65. Epub 2017 Dec 15 doi: 10.2217/cns-2017-0026. PMID: 29241354Free PMC Article
Central nervous system gliomas.
Reni M, Mazza E, Zanon S, Gatta G, Vecht CJ
Crit Rev Oncol Hematol 2017 May;113:213-234. Epub 2017 Mar 22 doi: 10.1016/j.critrevonc.2017.03.021. PMID: 28427510
Glioblastoma: Overview of Disease and Treatment.
Davis ME
Clin J Oncol Nurs 2016 Oct 1;20(5 Suppl):S2-8. doi: 10.1188/16.CJON.S1.2-8. PMID: 27668386Free PMC Article
Malignant gliomas in adults.
Wen PY, Kesari S
N Engl J Med 2008 Jul 31;359(5):492-507. doi: 10.1056/NEJMra0708126. PMID: 18669428

Therapy

IDH inhibition in gliomas: from preclinical models to clinical trials.
Rudà R, Horbinski C, van den Bent M, Preusser M, Soffietti R
Nat Rev Neurol 2024 Jul;20(7):395-407. Epub 2024 May 17 doi: 10.1038/s41582-024-00967-7. PMID: 38760442
Tumour treating fields therapy for glioblastoma: current advances and future directions.
Rominiyi O, Vanderlinden A, Clenton SJ, Bridgewater C, Al-Tamimi Y, Collis SJ
Br J Cancer 2021 Feb;124(4):697-709. Epub 2020 Nov 4 doi: 10.1038/s41416-020-01136-5. PMID: 33144698Free PMC Article
Postoperative stereotactic radiosurgery compared with whole brain radiotherapy for resected metastatic brain disease (NCCTG N107C/CEC·3): a multicentre, randomised, controlled, phase 3 trial.
Brown PD, Ballman KV, Cerhan JH, Anderson SK, Carrero XW, Whitton AC, Greenspoon J, Parney IF, Laack NNI, Ashman JB, Bahary JP, Hadjipanayis CG, Urbanic JJ, Barker FG 2nd, Farace E, Khuntia D, Giannini C, Buckner JC, Galanis E, Roberge D
Lancet Oncol 2017 Aug;18(8):1049-1060. Epub 2017 Jul 4 doi: 10.1016/S1470-2045(17)30441-2. PMID: 28687377Free PMC Article
Response assessment criteria for brain metastases: proposal from the RANO group.
Lin NU, Lee EQ, Aoyama H, Barani IJ, Barboriak DP, Baumert BG, Bendszus M, Brown PD, Camidge DR, Chang SM, Dancey J, de Vries EG, Gaspar LE, Harris GJ, Hodi FS, Kalkanis SN, Linskey ME, Macdonald DR, Margolin K, Mehta MP, Schiff D, Soffietti R, Suh JH, van den Bent MJ, Vogelbaum MA, Wen PY; Response Assessment in Neuro-Oncology (RANO) group
Lancet Oncol 2015 Jun;16(6):e270-8. Epub 2015 May 27 doi: 10.1016/S1470-2045(15)70057-4. PMID: 26065612
Malignant gliomas in adults.
Wen PY, Kesari S
N Engl J Med 2008 Jul 31;359(5):492-507. doi: 10.1056/NEJMra0708126. PMID: 18669428

Prognosis

Stereotactic Radiosurgery for Intracranial Primary Melanocytomas.
Dar N, Mantziaris G, Pikis S, Young L, Sheehan J
World Neurosurg 2022 Aug;164:160-166. Epub 2022 May 10 doi: 10.1016/j.wneu.2022.04.136. PMID: 35552031
CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2012-2016.
Ostrom QT, Cioffi G, Gittleman H, Patil N, Waite K, Kruchko C, Barnholtz-Sloan JS
Neuro Oncol 2019 Nov 1;21(Suppl 5):v1-v100. doi: 10.1093/neuonc/noz150. PMID: 31675094Free PMC Article
Survival Analysis of Glioblastoma Multiforme.
Witthayanuwat S, Pesee M, Supaadirek C, Supakalin N, Thamronganantasakul K, Krusun S
Asian Pac J Cancer Prev 2018 Sep 26;19(9):2613-2617. doi: 10.22034/APJCP.2018.19.9.2613. PMID: 30256068Free PMC Article
Post-operative stereotactic radiosurgery versus observation for completely resected brain metastases: a single-centre, randomised, controlled, phase 3 trial.
Mahajan A, Ahmed S, McAleer MF, Weinberg JS, Li J, Brown P, Settle S, Prabhu SS, Lang FF, Levine N, McGovern S, Sulman E, McCutcheon IE, Azeem S, Cahill D, Tatsui C, Heimberger AB, Ferguson S, Ghia A, Demonte F, Raza S, Guha-Thakurta N, Yang J, Sawaya R, Hess KR, Rao G
Lancet Oncol 2017 Aug;18(8):1040-1048. Epub 2017 Jul 4 doi: 10.1016/S1470-2045(17)30414-X. PMID: 28687375Free PMC Article
Malignant gliomas in adults.
Wen PY, Kesari S
N Engl J Med 2008 Jul 31;359(5):492-507. doi: 10.1056/NEJMra0708126. PMID: 18669428

Clinical prediction guides

Metabolism in the progression and metastasis of brain tumors.
Tyagi A, Wu SY, Watabe K
Cancer Lett 2022 Jul 28;539:215713. Epub 2022 May 2 doi: 10.1016/j.canlet.2022.215713. PMID: 35513201Free PMC Article
Brain metastases: An update on the multi-disciplinary approach of clinical management.
Mitchell DK, Kwon HJ, Kubica PA, Huff WX, O'Regan R, Dey M
Neurochirurgie 2022 Jan;68(1):69-85. Epub 2021 Apr 14 doi: 10.1016/j.neuchi.2021.04.001. PMID: 33864773Free PMC Article
Extrachromosomal DNA: Redefining the pathogenesis of glioblastoma.
Shiras A, Mondal A
Biochim Biophys Acta Rev Cancer 2021 Aug;1876(1):188551. Epub 2021 Apr 20 doi: 10.1016/j.bbcan.2021.188551. PMID: 33892052
Epidemiology and Overview of Gliomas.
Davis ME
Semin Oncol Nurs 2018 Dec;34(5):420-429. Epub 2018 Nov 2 doi: 10.1016/j.soncn.2018.10.001. PMID: 30392758
Subdural Hematoma Mimickers: A Systematic Review.
Catana D, Koziarz A, Cenic A, Nath S, Singh S, Almenawer SA, Kachur E
World Neurosurg 2016 Sep;93:73-80. Epub 2016 Jun 4 doi: 10.1016/j.wneu.2016.05.084. PMID: 27268313

Recent systematic reviews

Surgical Management of Adult Brainstem Gliomas: A Systematic Review and Meta-Analysis.
Ius T, Lombardi G, Baiano C, Berardinelli J, Romano A, Montemurro N, Cavallo LM, Pasqualetti F, Feletti A
Curr Oncol 2023 Nov 7;30(11):9772-9785. doi: 10.3390/curroncol30110709. PMID: 37999129Free PMC Article
Palliative care and end-of-life care in adults with malignant brain tumors.
Koekkoek JAF, van der Meer PB, Pace A, Hertler C, Harrison R, Leeper HE, Forst DA, Jalali R, Oliver K, Philip J, Taphoorn MJB, Dirven L, Walbert T
Neuro Oncol 2023 Mar 14;25(3):447-456. doi: 10.1093/neuonc/noac216. PMID: 36271873Free PMC Article
Therapy for Diffuse Astrocytic and Oligodendroglial Tumors in Adults: ASCO-SNO Guideline.
Mohile NA, Messersmith H, Gatson NT, Hottinger AF, Lassman A, Morton J, Ney D, Nghiemphu PL, Olar A, Olson J, Perry J, Portnow J, Schiff D, Shannon A, Shih HA, Strowd R, van den Bent M, Ziu M, Blakeley J
J Clin Oncol 2022 Feb 1;40(4):403-426. Epub 2021 Dec 13 doi: 10.1200/JCO.21.02036. PMID: 34898238
Association of the Extent of Resection With Survival in Glioblastoma: A Systematic Review and Meta-analysis.
Brown TJ, Brennan MC, Li M, Church EW, Brandmeir NJ, Rakszawski KL, Patel AS, Rizk EB, Suki D, Sawaya R, Glantz M
JAMA Oncol 2016 Nov 1;2(11):1460-1469. doi: 10.1001/jamaoncol.2016.1373. PMID: 27310651Free PMC Article
Brain metastases.
Rosenfelder N, Khoo V
BMJ Clin Evid 2011 Jul 26;2011 PMID: 21791125Free PMC Article

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