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Adverse Event Associated with Hemorrhage and Bleeding

MedGen UID:
327270
Concept ID:
C1560575
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdverse Event Associated with Hemorrhage and Bleeding

Professional guidelines

PubMed

Bayard M, Gerayli F, Holt J
Am Fam Physician 2023 Nov;108(5):454-463. PMID: 37983697
Farge D, Frere C, Connors JM, Khorana AA, Kakkar A, Ay C, Muñoz A, Brenner B, Prata PH, Brilhante D, Antic D, Casais P, Guillermo Esposito MC, Ikezoe T, Abutalib SA, Meillon-García LA, Bounameaux H, Pabinger I, Douketis J; International Initiative on Thrombosis and Cancer (ITAC) advisory panel
Lancet Oncol 2022 Jul;23(7):e334-e347. doi: 10.1016/S1470-2045(22)00160-7. PMID: 35772465Free PMC Article
Smilowitz NR, Berger JS
JAMA 2020 Jul 21;324(3):279-290. doi: 10.1001/jama.2020.7840. PMID: 32692391

Recent clinical studies

Etiology

Connolly SJ, Sharma M, Cohen AT, Demchuk AM, Członkowska A, Lindgren AG, Molina CA, Bereczki D, Toni D, Seiffge DJ, Tanne D, Sandset EC, Tsivgoulis G, Christensen H, Beyer-Westendorf J, Coutinho JM, Crowther M, Verhamme P, Amarenco P, Roine RO, Mikulik R, Lemmens R, Veltkamp R, Middeldorp S, Robinson TG, Milling TJ Jr, Tedim-Cruz V, Lang W, Himmelmann A, Ladenvall P, Knutsson M, Ekholm E, Law A, Taylor A, Karyakina T, Xu L, Tsiplova K, Poli S, Kallmünzer B, Gumbinger C, Shoamanesh A; ANNEXA-I Investigators
N Engl J Med 2024 May 16;390(19):1745-1755. doi: 10.1056/NEJMoa2313040. PMID: 38749032
Ozelo MC, Mahlangu J, Pasi KJ, Giermasz A, Leavitt AD, Laffan M, Symington E, Quon DV, Wang JD, Peerlinck K, Pipe SW, Madan B, Key NS, Pierce GF, O'Mahony B, Kaczmarek R, Henshaw J, Lawal A, Jayaram K, Huang M, Yang X, Wong WY, Kim B; GENEr8-1 Trial Group
N Engl J Med 2022 Mar 17;386(11):1013-1025. doi: 10.1056/NEJMoa2113708. PMID: 35294811
Clarkson E, Jung E, Lin S
Dent Clin North Am 2021 Jan;65(1):33-41. doi: 10.1016/j.cden.2020.09.002. PMID: 33213713
Grottke O, Mallaiah S, Karkouti K, Saner F, Haas T
Semin Thromb Hemost 2020 Feb;46(1):38-49. Epub 2019 Oct 1 doi: 10.1055/s-0039-1696946. PMID: 31574543
Castilla-Guerra L, Fernández-Moreno MDC, de la Vega-Sánchez JM, Leon Jimenez D
Clin Investig Arterioscler 2019 Nov-Dec;31(6):282-288. Epub 2019 Apr 17 doi: 10.1016/j.arteri.2019.01.006. PMID: 31005341

Diagnosis

Xie Y, Zhu L, Wang Z, Zhan X, Peng F, Feng X, Zhou Q, Wu X, Wang X, Su N, Tang X, Zhang Y, Zeng Y, Li M, Liang J, Liu L, Wen Y
Clin Exp Nephrol 2022 Mar;26(3):278-285. Epub 2021 Oct 26 doi: 10.1007/s10157-021-02150-4. PMID: 34698915
Barrios RHS, Burguera Vion V, Álvarez Nadal M, Cintra Cabrera M, Elías Triviño S, Villa Hurtado D, Ortego S, Fernández Lucas M, Rivera-Gorrin M
J Int Med Res 2021 Sep;49(9):3000605211040764. doi: 10.1177/03000605211040764. PMID: 34590925Free PMC Article
Connolly SJ, Crowther M, Eikelboom JW, Gibson CM, Curnutte JT, Lawrence JH, Yue P, Bronson MD, Lu G, Conley PB, Verhamme P, Schmidt J, Middeldorp S, Cohen AT, Beyer-Westendorf J, Albaladejo P, Lopez-Sendon J, Demchuk AM, Pallin DJ, Concha M, Goodman S, Leeds J, Souza S, Siegal DM, Zotova E, Meeks B, Ahmad S, Nakamya J, Milling TJ Jr; ANNEXA-4 Investigators
N Engl J Med 2019 Apr 4;380(14):1326-1335. Epub 2019 Feb 7 doi: 10.1056/NEJMoa1814051. PMID: 30730782Free PMC Article
Kulkarni R, Soucie JM
Semin Thromb Hemost 2011 Oct;37(7):737-44. Epub 2011 Dec 20 doi: 10.1055/s-0031-1297164. PMID: 22187396
Chu TG, Green RL
Surv Ophthalmol 1999 May-Jun;43(6):471-86. doi: 10.1016/s0039-6257(99)00037-5. PMID: 10416790

Therapy

Connolly SJ, Sharma M, Cohen AT, Demchuk AM, Członkowska A, Lindgren AG, Molina CA, Bereczki D, Toni D, Seiffge DJ, Tanne D, Sandset EC, Tsivgoulis G, Christensen H, Beyer-Westendorf J, Coutinho JM, Crowther M, Verhamme P, Amarenco P, Roine RO, Mikulik R, Lemmens R, Veltkamp R, Middeldorp S, Robinson TG, Milling TJ Jr, Tedim-Cruz V, Lang W, Himmelmann A, Ladenvall P, Knutsson M, Ekholm E, Law A, Taylor A, Karyakina T, Xu L, Tsiplova K, Poli S, Kallmünzer B, Gumbinger C, Shoamanesh A; ANNEXA-I Investigators
N Engl J Med 2024 May 16;390(19):1745-1755. doi: 10.1056/NEJMoa2313040. PMID: 38749032
Ozelo MC, Mahlangu J, Pasi KJ, Giermasz A, Leavitt AD, Laffan M, Symington E, Quon DV, Wang JD, Peerlinck K, Pipe SW, Madan B, Key NS, Pierce GF, O'Mahony B, Kaczmarek R, Henshaw J, Lawal A, Jayaram K, Huang M, Yang X, Wong WY, Kim B; GENEr8-1 Trial Group
N Engl J Med 2022 Mar 17;386(11):1013-1025. doi: 10.1056/NEJMoa2113708. PMID: 35294811
Clarkson E, Jung E, Lin S
Dent Clin North Am 2021 Jan;65(1):33-41. doi: 10.1016/j.cden.2020.09.002. PMID: 33213713
Grottke O, Mallaiah S, Karkouti K, Saner F, Haas T
Semin Thromb Hemost 2020 Feb;46(1):38-49. Epub 2019 Oct 1 doi: 10.1055/s-0039-1696946. PMID: 31574543
Kulkarni R, Soucie JM
Semin Thromb Hemost 2011 Oct;37(7):737-44. Epub 2011 Dec 20 doi: 10.1055/s-0031-1297164. PMID: 22187396

Prognosis

Nunez JI, Gosling AF, O'Gara B, Kennedy KF, Rycus P, Abrams D, Brodie D, Shaefi S, Garan AR, Grandin EW
Intensive Care Med 2022 Feb;48(2):213-224. Epub 2021 Dec 18 doi: 10.1007/s00134-021-06593-x. PMID: 34921625Free PMC Article
Karcioglu O, Zengin S, Ozkaya B, Ersan E, Yilmaz S, Afacan G, Abuska D, Hosseinzadeh M, Yeniocak S
Cardiovasc Hematol Agents Med Chem 2022;20(2):103-113. doi: 10.2174/1871525719666210914110750. PMID: 34521332
Callaghan MU, Negrier C, Paz-Priel I, Chang T, Chebon S, Lehle M, Mahlangu J, Young G, Kruse-Jarres R, Mancuso ME, Niggli M, Howard M, Bienz NS, Shima M, Jiménez-Yuste V, Schmitt C, Asikanius E, Levy GG, Pipe SW, Oldenburg J
Blood 2021 Apr 22;137(16):2231-2242. doi: 10.1182/blood.2020009217. PMID: 33512413Free PMC Article
Castilla-Guerra L, Fernández-Moreno MDC, de la Vega-Sánchez JM, Leon Jimenez D
Clin Investig Arterioscler 2019 Nov-Dec;31(6):282-288. Epub 2019 Apr 17 doi: 10.1016/j.arteri.2019.01.006. PMID: 31005341
Egea-Guerrero JJ, Quintana Díaz M
Med Intensiva 2015 Apr;39(3):167-71. Epub 2014 Dec 13 doi: 10.1016/j.medin.2014.09.008. PMID: 25510394

Clinical prediction guides

Connolly SJ, Sharma M, Cohen AT, Demchuk AM, Członkowska A, Lindgren AG, Molina CA, Bereczki D, Toni D, Seiffge DJ, Tanne D, Sandset EC, Tsivgoulis G, Christensen H, Beyer-Westendorf J, Coutinho JM, Crowther M, Verhamme P, Amarenco P, Roine RO, Mikulik R, Lemmens R, Veltkamp R, Middeldorp S, Robinson TG, Milling TJ Jr, Tedim-Cruz V, Lang W, Himmelmann A, Ladenvall P, Knutsson M, Ekholm E, Law A, Taylor A, Karyakina T, Xu L, Tsiplova K, Poli S, Kallmünzer B, Gumbinger C, Shoamanesh A; ANNEXA-I Investigators
N Engl J Med 2024 May 16;390(19):1745-1755. doi: 10.1056/NEJMoa2313040. PMID: 38749032
Davenport R, Curry N, Fox EE, Thomas H, Lucas J, Evans A, Shanmugaranjan S, Sharma R, Deary A, Edwards A, Green L, Wade CE, Benger JR, Cotton BA, Stanworth SJ, Brohi K; CRYOSTAT-2 Principal Investigators
JAMA 2023 Nov 21;330(19):1882-1891. doi: 10.1001/jama.2023.21019. PMID: 37824155Free PMC Article
Nunez JI, Gosling AF, O'Gara B, Kennedy KF, Rycus P, Abrams D, Brodie D, Shaefi S, Garan AR, Grandin EW
Intensive Care Med 2022 Feb;48(2):213-224. Epub 2021 Dec 18 doi: 10.1007/s00134-021-06593-x. PMID: 34921625Free PMC Article
Inoue F, Ichiba T, Naitou H
Intern Med 2021 Jan 1;60(1):151-153. Epub 2020 Aug 12 doi: 10.2169/internalmedicine.4800-20. PMID: 32788535Free PMC Article
Connolly SJ, Crowther M, Eikelboom JW, Gibson CM, Curnutte JT, Lawrence JH, Yue P, Bronson MD, Lu G, Conley PB, Verhamme P, Schmidt J, Middeldorp S, Cohen AT, Beyer-Westendorf J, Albaladejo P, Lopez-Sendon J, Demchuk AM, Pallin DJ, Concha M, Goodman S, Leeds J, Souza S, Siegal DM, Zotova E, Meeks B, Ahmad S, Nakamya J, Milling TJ Jr; ANNEXA-4 Investigators
N Engl J Med 2019 Apr 4;380(14):1326-1335. Epub 2019 Feb 7 doi: 10.1056/NEJMoa1814051. PMID: 30730782Free PMC Article

Recent systematic reviews

Khairani CD, Bejjani A, Piazza G, Jimenez D, Monreal M, Chatterjee S, Pengo V, Woller SC, Cortes-Hernandez J, Connors JM, Kanthi Y, Krumholz HM, Middeldorp S, Falanga A, Cushman M, Goldhaber SZ, Garcia DA, Bikdeli B
J Am Coll Cardiol 2023 Jan 3;81(1):16-30. Epub 2022 Oct 31 doi: 10.1016/j.jacc.2022.10.008. PMID: 36328154Free PMC Article
US Preventive Services Task Force, Davidson KW, Barry MJ, Mangione CM, Cabana M, Chelmow D, Coker TR, Davis EM, Donahue KE, Jaén CR, Krist AH, Kubik M, Li L, Ogedegbe G, Pbert L, Ruiz JM, Stevermer J, Tseng CW, Wong JB
JAMA 2022 Apr 26;327(16):1577-1584. doi: 10.1001/jama.2022.4983. PMID: 35471505
Wang M, Zeraatkar D, Obeda M, Lee M, Garcia C, Nguyen L, Agarwal A, Al-Shalabi F, Benipal H, Ahmad A, Abbas M, Vidug K, Holbrook A
Br J Clin Pharmacol 2021 Nov;87(11):4051-4100. Epub 2021 May 16 doi: 10.1111/bcp.14833. PMID: 33769581
Jacobson B, Rambiritch V, Paek D, Sayre T, Naidoo P, Shan J, Leisegang R
Adv Ther 2020 Jan;37(1):27-40. Epub 2019 Oct 31 doi: 10.1007/s12325-019-01124-z. PMID: 31673991Free PMC Article
Zheng SL, Roddick AJ
JAMA 2019 Jan 22;321(3):277-287. doi: 10.1001/jama.2018.20578. PMID: 30667501Free PMC Article

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