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Carotid intimal medial thickness 1(CIMT1)

MedGen UID:
332175
•Concept ID:
C1836302
•
Disease or Syndrome
Synonyms: Cardiovascular Disease Risk Factor (Carotid Intimal Medial Thickness 1); CIMT1; INTIMAL MEDIAL THICKNESS OF INTERNAL CAROTID ARTERY
 
Gene (location): PPARG (3p25.2)
 
OMIM®: 609338

Professional guidelines

PubMed

Statin treatment of children with familial hypercholesterolemia--trying to balance incomplete evidence of long-term safety and clinical accountability: are we approaching a consensus?
Vuorio A, Docherty KF, Humphries SE, Kuoppala J, Kovanen PT
Atherosclerosis 2013 Feb;226(2):315-20. Epub 2012 Oct 12 doi: 10.1016/j.atherosclerosis.2012.10.032. PMID: 23141908

Recent clinical studies

Etiology

Lack of evidence of the correlation between plasma Asymmetrical Dimethylarginine correlation and IMT in type 2 diabetic patients with chronic vascular complication.
Fiodorenko-Dumas Z, Dumas I, Rabczynski M, Małecki R, Adamiec R, Paprocka-Borowicz M
Acta Biochim Pol 2021 Feb 5;68(1):143-149. doi: 10.18388/abp.2020_5424. PMID: 33543609
Undercarboxylated osteocalcin as a biomarker of subclinical atherosclerosis in non-dialysis patients with chronic kidney disease.
Zhang M, Ni Z, Zhou W, Qian J
J Biomed Sci 2015 Sep 17;22(1):75. doi: 10.1186/s12929-015-0183-6. PMID: 26381729Free PMC Article
Relationship between carotid artery atherosclerosis and sulfatide in hypertensive patients.
Li G, Hu R, Gu J, Wu HZ
Genet Mol Res 2015 May 11;14(2):4840-6. doi: 10.4238/2015.May.11.16. PMID: 25966258
Markers of cardiovascular risk in patients with antiphospholipid syndrome: a meta-analysis of literature studies.
Ambrosino P, Lupoli R, Di Minno A, Iervolino S, Peluso R, Di Minno MN
Ann Med 2014 Dec;46(8):693-702. Epub 2014 Oct 13 doi: 10.3109/07853890.2014.959559. PMID: 25307359
Statin treatment of children with familial hypercholesterolemia--trying to balance incomplete evidence of long-term safety and clinical accountability: are we approaching a consensus?
Vuorio A, Docherty KF, Humphries SE, Kuoppala J, Kovanen PT
Atherosclerosis 2013 Feb;226(2):315-20. Epub 2012 Oct 12 doi: 10.1016/j.atherosclerosis.2012.10.032. PMID: 23141908

Diagnosis

Lack of evidence of the correlation between plasma Asymmetrical Dimethylarginine correlation and IMT in type 2 diabetic patients with chronic vascular complication.
Fiodorenko-Dumas Z, Dumas I, Rabczynski M, Małecki R, Adamiec R, Paprocka-Borowicz M
Acta Biochim Pol 2021 Feb 5;68(1):143-149. doi: 10.18388/abp.2020_5424. PMID: 33543609
Serum levels of anticyclic citrullinated peptide antibodies, interleukin-6, tumor necrosis factor-α, and C-reactive protein are associated with increased carotid intima-media thickness: a cross-sectional analysis of a cohort of rheumatoid arthritis patients without cardiovascular risk factors.
Vázquez-Del Mercado M, Nuñez-Atahualpa L, Figueroa-Sánchez M, Gómez-Bañuelos E, Rocha-Muñoz AD, Martín-Márquez BT, Corona-Sanchez EG, Martínez-García EA, Macias-Reyes H, Gonzalez-Lopez L, Gamez-Nava JI, Navarro-Hernandez RE, Nuñez-Atahualpa MA, Andrade-Garduño J
Biomed Res Int 2015;2015:342649. Epub 2015 Mar 2 doi: 10.1155/2015/342649. PMID: 25821796Free PMC Article
The effect of obstructive sleep apnea syndrome and snoring severity to intima-media thickening of carotid artery.
Salepci B, Fidan A, Ketenci SC, Parmaksiz ET, Comert SS, Kiral N, Akturk UA, Caglayan B, Salepci E
Sleep Breath 2015 Mar;19(1):239-46. Epub 2014 May 22 doi: 10.1007/s11325-014-1002-0. PMID: 24849256
Clinical determinants of carotid intima-media thickness in patients with diabetes mellitus type 2.
Bartman W, Pierzchała K
Neurol Neurochir Pol 2012 Nov-Dec;46(6):519-28. doi: 10.5114/ninp.2012.32278. PMID: 23319219
Premature subclinical atherosclerosis in pediatric inflammatory bowel disease.
Aloi M, Tromba L, Di Nardo G, Dilillo A, Del Giudice E, Marocchi E, Viola F, Civitelli F, Berni A, Cucchiara S
J Pediatr 2012 Oct;161(4):589-94.e1. Epub 2012 May 10 doi: 10.1016/j.jpeds.2012.03.043. PMID: 22579000

Therapy

Undercarboxylated osteocalcin as a biomarker of subclinical atherosclerosis in non-dialysis patients with chronic kidney disease.
Zhang M, Ni Z, Zhou W, Qian J
J Biomed Sci 2015 Sep 17;22(1):75. doi: 10.1186/s12929-015-0183-6. PMID: 26381729Free PMC Article
Comparison of mercury sphygmomanometry blood pressure readings with oscillometric and central blood pressure in predicting target organ damage in youth.
Urbina EM, Khoury PR, McCoy CE, Daniels SR, Dolan LM, Kimball TR
Blood Press Monit 2015 Jun;20(3):150-6. doi: 10.1097/MBP.0000000000000110. PMID: 25647284Free PMC Article
Rationale and design of the Kronos Early Estrogen Prevention Study (KEEPS) and the KEEPS Cognitive and Affective sub study (KEEPS Cog).
Wharton W, Gleason CE, Miller VM, Asthana S
Brain Res 2013 Jun 13;1514:12-7. Epub 2013 Apr 17 doi: 10.1016/j.brainres.2013.04.011. PMID: 23603409Free PMC Article
Statin treatment of children with familial hypercholesterolemia--trying to balance incomplete evidence of long-term safety and clinical accountability: are we approaching a consensus?
Vuorio A, Docherty KF, Humphries SE, Kuoppala J, Kovanen PT
Atherosclerosis 2013 Feb;226(2):315-20. Epub 2012 Oct 12 doi: 10.1016/j.atherosclerosis.2012.10.032. PMID: 23141908

Prognosis

Serum levels of anticyclic citrullinated peptide antibodies, interleukin-6, tumor necrosis factor-α, and C-reactive protein are associated with increased carotid intima-media thickness: a cross-sectional analysis of a cohort of rheumatoid arthritis patients without cardiovascular risk factors.
Vázquez-Del Mercado M, Nuñez-Atahualpa L, Figueroa-Sánchez M, Gómez-Bañuelos E, Rocha-Muñoz AD, Martín-Márquez BT, Corona-Sanchez EG, Martínez-García EA, Macias-Reyes H, Gonzalez-Lopez L, Gamez-Nava JI, Navarro-Hernandez RE, Nuñez-Atahualpa MA, Andrade-Garduño J
Biomed Res Int 2015;2015:342649. Epub 2015 Mar 2 doi: 10.1155/2015/342649. PMID: 25821796Free PMC Article
Comparison of mercury sphygmomanometry blood pressure readings with oscillometric and central blood pressure in predicting target organ damage in youth.
Urbina EM, Khoury PR, McCoy CE, Daniels SR, Dolan LM, Kimball TR
Blood Press Monit 2015 Jun;20(3):150-6. doi: 10.1097/MBP.0000000000000110. PMID: 25647284Free PMC Article
Pulse pressure and subclinical cardiovascular disease in the multi-ethnic study of atherosclerosis.
Winston GJ, Palmas W, Lima J, Polak JF, Bertoni AG, Burke G, Eng J, Gottesman R, Shea S
Am J Hypertens 2013 May;26(5):636-42. Epub 2013 Feb 6 doi: 10.1093/ajh/hps092. PMID: 23388832Free PMC Article
Psychological factors, including alexithymia, in the prediction of cardiovascular risk in HIV infected patients: results of a cohort study.
Parruti G, Vadini F, Sozio F, Mazzott E, Ursini T, Polill E, Di Stefano P, Tontodonati M, Verrocchio MC, Fulcheri M, Calella G, Santilli F, Manzoli L
PLoS One 2013;8(1):e54555. Epub 2013 Jan 22 doi: 10.1371/journal.pone.0054555. PMID: 23349927Free PMC Article
Clinical determinants of carotid intima-media thickness in patients with diabetes mellitus type 2.
Bartman W, Pierzchała K
Neurol Neurochir Pol 2012 Nov-Dec;46(6):519-28. doi: 10.5114/ninp.2012.32278. PMID: 23319219

Clinical prediction guides

Serum levels of anticyclic citrullinated peptide antibodies, interleukin-6, tumor necrosis factor-α, and C-reactive protein are associated with increased carotid intima-media thickness: a cross-sectional analysis of a cohort of rheumatoid arthritis patients without cardiovascular risk factors.
Vázquez-Del Mercado M, Nuñez-Atahualpa L, Figueroa-Sánchez M, Gómez-Bañuelos E, Rocha-Muñoz AD, Martín-Márquez BT, Corona-Sanchez EG, Martínez-García EA, Macias-Reyes H, Gonzalez-Lopez L, Gamez-Nava JI, Navarro-Hernandez RE, Nuñez-Atahualpa MA, Andrade-Garduño J
Biomed Res Int 2015;2015:342649. Epub 2015 Mar 2 doi: 10.1155/2015/342649. PMID: 25821796Free PMC Article
Quantification of Internal Carotid Artery Stenosis with 3D Ultrasound Angiography.
Pelz JO, Weinreich A, Fritzsch D, Saur D
Ultraschall Med 2015 Oct;36(5):487-93. Epub 2015 Jan 21 doi: 10.1055/s-0034-1398749. PMID: 25607630
Serum 25-hydroxyvitamin D concentration in subclinical carotid atherosclerosis.
Deleskog A, Piksasova O, Silveira A, Gertow K, Baldassarre D, Veglia F, Sennblad B, Strawbridge RJ, Larsson M, Leander K, Gigante B, Kauhanen J, Rauramaa R, Smit AJ, Mannarino E, Giral P, Gustafsson S, Östenson CG, Humphries SE, Tremoli E, de Faire U, Öhrvik J, Hamsten A
Arterioscler Thromb Vasc Biol 2013 Nov;33(11):2633-8. Epub 2013 Sep 26 doi: 10.1161/ATVBAHA.113.301593. PMID: 24072691
Psychological factors, including alexithymia, in the prediction of cardiovascular risk in HIV infected patients: results of a cohort study.
Parruti G, Vadini F, Sozio F, Mazzott E, Ursini T, Polill E, Di Stefano P, Tontodonati M, Verrocchio MC, Fulcheri M, Calella G, Santilli F, Manzoli L
PLoS One 2013;8(1):e54555. Epub 2013 Jan 22 doi: 10.1371/journal.pone.0054555. PMID: 23349927Free PMC Article
Clinical determinants of carotid intima-media thickness in patients with diabetes mellitus type 2.
Bartman W, Pierzchała K
Neurol Neurochir Pol 2012 Nov-Dec;46(6):519-28. doi: 10.5114/ninp.2012.32278. PMID: 23319219

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