From HPO
Abnormality of blood and blood-forming tissues- MedGen UID:
- 163092
- •Concept ID:
- C0850715
- •
- Finding
An abnormality of the hematopoietic system.
Immunodeficiency- MedGen UID:
- 7034
- •Concept ID:
- C0021051
- •
- Disease or Syndrome
Failure of the immune system to protect the body adequately from infection, due to the absence or insufficiency of some component process or substance.
Meningitis- MedGen UID:
- 6298
- •Concept ID:
- C0025289
- •
- Disease or Syndrome
Inflammation of the meninges.
Onychomycosis- MedGen UID:
- 11825
- •Concept ID:
- C0040261
- •
- Disease or Syndrome
A fungal infection of the toenails or fingernails that tends to cause the nails to thicken, discolor, disfigure, and split.
Increased circulating IgE level- MedGen UID:
- 116018
- •Concept ID:
- C0236175
- •
- Finding
An abnormally increased overall level of immunoglobulin E in blood.
Phaeohyphomycosis- MedGen UID:
- 452374
- •Concept ID:
- C0276721
- •
- Disease or Syndrome
Phaeohyphomycosis refers to infections due to a large group of heterogenous organisms called dematiaceous or melanized fungi. These fungi are distinguished by the predominance of melanin in their cell walls, which likely acts as a virulence factor. Virtually, everyone is exposed to dematiaceous fungi through inhalation, as they are ubiquitous in the environment, although the development of infection is extremely uncommon.
Lymphadenopathy- MedGen UID:
- 96929
- •Concept ID:
- C0497156
- •
- Disease or Syndrome
Enlargement (swelling) of a lymph node.
Hypereosinophilia- MedGen UID:
- 148170
- •Concept ID:
- C0745091
- •
- Disease or Syndrome
A severely increased count of eosinophils in the blood defined as a blood eosinophil count of at least 1.5 billion cells per liter.
Deep dermatophytosis- MedGen UID:
- 235599
- •Concept ID:
- C1395264
- •
- Disease or Syndrome
A type of invasive dermatophyte infection of the deep dermis characterized by extensive dermal infiltration by fungal elements.
Abnormal natural killer cell count- MedGen UID:
- 866689
- •Concept ID:
- C4021036
- •
- Finding
Any deviation from the normal overall count of natural killer (NK) cells in the circulation or a deviation from the normal distribution of NK cell subtypes.
Abnormal B cell count- MedGen UID:
- 866853
- •Concept ID:
- C4021208
- •
- Finding
A deviation from the normal count of B cells, i.e., the cells that are formed in the bone marrow, migrate to the peripheral lymphatic system, and mature into plasma cells or memory cells.
Chronic oral candidiasis- MedGen UID:
- 870166
- •Concept ID:
- C4024599
- •
- Disease or Syndrome
Chronic accumulation and overgrowth of the fungus Candida albicans on the mucous membranes of the mouth, generally manifested as associated with creamy white lesions on the tongue or inner cheeks, occasionally spreading to the gums, tonsils, palate or oropharynx.
Abnormal proportion of CD8-positive T cells- MedGen UID:
- 1627283
- •Concept ID:
- C4531155
- •
- Finding
Any abnormality in the proportion of CD8 T cells relative to the total number of T cells.
Abnormal proportion of CD4-positive T cells- MedGen UID:
- 1619121
- •Concept ID:
- C4531156
- •
- Finding
Any abnormality in the proportion of CD4-positive T cells relative to the total number of T cells.
Chronic tinea infection- MedGen UID:
- 1685152
- •Concept ID:
- C5139226
- •
- Disease or Syndrome
The term tinea means fungal infection, whereas dermatophyte refers to the fungal organisms that cause tinea. This term refers to a tinea infection that is chronic or recalcitrant to treatment and may be reflective of an immune defect.
Decreased circulating iron concentration- MedGen UID:
- 65918
- •Concept ID:
- C0235988
- •
- Finding
The concentration of iron in the blood circulation is below the lower limit of normal.
- Abnormality of blood and blood-forming tissues
- Abnormality of metabolism/homeostasis
- Abnormality of the immune system