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Viral Hepatitis, CTCAE

MedGen UID:
369785
•Concept ID:
C1963279
•
Finding

Recent clinical studies

Etiology

Incidence and severity of immune-related hepatitis after dual checkpoint therapy is linked to younger age independent of herpes virus immunity.
Zhang Z, Rafei-Shamsabadi D, Lehr S, Buettner N, Diehl R, Huzly D, Pinato DJ, Thimme R, Meiss F, Bengsch B
J Transl Med 2022 Dec 12;20(1):582. doi: 10.1186/s12967-022-03755-3. PMID: 36503532Free PMC Article
The normal tissue complication probability model-based approach considering uncertainties for the selective use of radiation modality in primary liver cancer patients.
Prayongrat A, Kobashi K, Ito YM, Katoh N, Tamura M, Dekura Y, Toramatsu C, Khorprasert C, Amornwichet N, Alisanant P, Shirato H, Shimizu S
Radiother Oncol 2019 Jun;135:100-106. Epub 2019 Mar 19 doi: 10.1016/j.radonc.2019.03.003. PMID: 31015154
Safety and efficacy of anti-PD-1 therapy for metastatic melanoma and non-small-cell lung cancer in patients with viral hepatitis: a case series.
Kothapalli A, Khattak MA
Melanoma Res 2018 Apr;28(2):155-158. doi: 10.1097/CMR.0000000000000434. PMID: 29406396

Diagnosis

Life-threatening Autoimmune Cardiomyopathy Reproducibly Induced in a Patient by Checkpoint Inhibitor Therapy.
Tajmir-Riahi A, Bergmann T, Schmid M, Agaimy A, Schuler G, Heinzerling L
J Immunother 2018 Jan;41(1):35-38. doi: 10.1097/CJI.0000000000000190. PMID: 29077601
Autoimmune Colitis and Subsequent CMV-induced Hepatitis After Treatment With Ipilimumab.
Uslu U, Agaimy A, Hundorfean G, Harrer T, Schuler G, Heinzerling L
J Immunother 2015 Jun;38(5):212-5. doi: 10.1097/CJI.0000000000000081. PMID: 25962110

Therapy

Reproducible safety and efficacy of atezolizumab plus bevacizumab for HCC in clinical practice: Results of the AB-real study.
Fulgenzi CAM, Cheon J, D'Alessio A, Nishida N, Ang C, Marron TU, Wu L, Saeed A, Wietharn B, Cammarota A, Pressiani T, Personeni N, Pinter M, Scheiner B, Balcar L, Napolitano A, Huang YH, Phen S, Naqash AR, Vivaldi C, Salani F, Masi G, Bettinger D, Vogel A, Schönlein M, von Felden J, Schulze K, Wege H, Galle PR, Kudo M, Rimassa L, Singal AG, Sharma R, Cortellini A, Gaillard VE, Chon HJ, Pinato DJ
Eur J Cancer 2022 Nov;175:204-213. Epub 2022 Sep 20 doi: 10.1016/j.ejca.2022.08.024. PMID: 36148739
Safety and efficacy of anti-PD-1 therapy for metastatic melanoma and non-small-cell lung cancer in patients with viral hepatitis: a case series.
Kothapalli A, Khattak MA
Melanoma Res 2018 Apr;28(2):155-158. doi: 10.1097/CMR.0000000000000434. PMID: 29406396
Life-threatening Autoimmune Cardiomyopathy Reproducibly Induced in a Patient by Checkpoint Inhibitor Therapy.
Tajmir-Riahi A, Bergmann T, Schmid M, Agaimy A, Schuler G, Heinzerling L
J Immunother 2018 Jan;41(1):35-38. doi: 10.1097/CJI.0000000000000190. PMID: 29077601
Autoimmune Colitis and Subsequent CMV-induced Hepatitis After Treatment With Ipilimumab.
Uslu U, Agaimy A, Hundorfean G, Harrer T, Schuler G, Heinzerling L
J Immunother 2015 Jun;38(5):212-5. doi: 10.1097/CJI.0000000000000081. PMID: 25962110

Prognosis

Incidence and severity of immune-related hepatitis after dual checkpoint therapy is linked to younger age independent of herpes virus immunity.
Zhang Z, Rafei-Shamsabadi D, Lehr S, Buettner N, Diehl R, Huzly D, Pinato DJ, Thimme R, Meiss F, Bengsch B
J Transl Med 2022 Dec 12;20(1):582. doi: 10.1186/s12967-022-03755-3. PMID: 36503532Free PMC Article
Reproducible safety and efficacy of atezolizumab plus bevacizumab for HCC in clinical practice: Results of the AB-real study.
Fulgenzi CAM, Cheon J, D'Alessio A, Nishida N, Ang C, Marron TU, Wu L, Saeed A, Wietharn B, Cammarota A, Pressiani T, Personeni N, Pinter M, Scheiner B, Balcar L, Napolitano A, Huang YH, Phen S, Naqash AR, Vivaldi C, Salani F, Masi G, Bettinger D, Vogel A, Schönlein M, von Felden J, Schulze K, Wege H, Galle PR, Kudo M, Rimassa L, Singal AG, Sharma R, Cortellini A, Gaillard VE, Chon HJ, Pinato DJ
Eur J Cancer 2022 Nov;175:204-213. Epub 2022 Sep 20 doi: 10.1016/j.ejca.2022.08.024. PMID: 36148739
The normal tissue complication probability model-based approach considering uncertainties for the selective use of radiation modality in primary liver cancer patients.
Prayongrat A, Kobashi K, Ito YM, Katoh N, Tamura M, Dekura Y, Toramatsu C, Khorprasert C, Amornwichet N, Alisanant P, Shirato H, Shimizu S
Radiother Oncol 2019 Jun;135:100-106. Epub 2019 Mar 19 doi: 10.1016/j.radonc.2019.03.003. PMID: 31015154
Life-threatening Autoimmune Cardiomyopathy Reproducibly Induced in a Patient by Checkpoint Inhibitor Therapy.
Tajmir-Riahi A, Bergmann T, Schmid M, Agaimy A, Schuler G, Heinzerling L
J Immunother 2018 Jan;41(1):35-38. doi: 10.1097/CJI.0000000000000190. PMID: 29077601

Clinical prediction guides

Incidence and severity of immune-related hepatitis after dual checkpoint therapy is linked to younger age independent of herpes virus immunity.
Zhang Z, Rafei-Shamsabadi D, Lehr S, Buettner N, Diehl R, Huzly D, Pinato DJ, Thimme R, Meiss F, Bengsch B
J Transl Med 2022 Dec 12;20(1):582. doi: 10.1186/s12967-022-03755-3. PMID: 36503532Free PMC Article
Reproducible safety and efficacy of atezolizumab plus bevacizumab for HCC in clinical practice: Results of the AB-real study.
Fulgenzi CAM, Cheon J, D'Alessio A, Nishida N, Ang C, Marron TU, Wu L, Saeed A, Wietharn B, Cammarota A, Pressiani T, Personeni N, Pinter M, Scheiner B, Balcar L, Napolitano A, Huang YH, Phen S, Naqash AR, Vivaldi C, Salani F, Masi G, Bettinger D, Vogel A, Schönlein M, von Felden J, Schulze K, Wege H, Galle PR, Kudo M, Rimassa L, Singal AG, Sharma R, Cortellini A, Gaillard VE, Chon HJ, Pinato DJ
Eur J Cancer 2022 Nov;175:204-213. Epub 2022 Sep 20 doi: 10.1016/j.ejca.2022.08.024. PMID: 36148739
The normal tissue complication probability model-based approach considering uncertainties for the selective use of radiation modality in primary liver cancer patients.
Prayongrat A, Kobashi K, Ito YM, Katoh N, Tamura M, Dekura Y, Toramatsu C, Khorprasert C, Amornwichet N, Alisanant P, Shirato H, Shimizu S
Radiother Oncol 2019 Jun;135:100-106. Epub 2019 Mar 19 doi: 10.1016/j.radonc.2019.03.003. PMID: 31015154

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