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Schizophrenia 12(SCZD12)

MedGen UID:
373838
•Concept ID:
C1837893
•
Disease or Syndrome
Synonyms: SCHIZOPHRENIA SUSCEPTIBILITY LOCUS, CHROMOSOME 1p-RELATED; SCZD12
 
Monarch Initiative: MONDO:0012054
OMIM®: 608543

Definition

A schizophrenia that has material basis in a mutation on chromosome 1p36.2. [from MONDO]

Professional guidelines

PubMed

Spinophilin expression in postmortem prefrontal cortex of schizophrenic subjects: Effects of antipsychotic treatment.
Brocos-Mosquera I, Gabilondo AM, Meana JJ, Callado LF, Erdozain AM
Eur Neuropsychopharmacol 2021 Jan;42:12-21. Epub 2020 Nov 27 doi: 10.1016/j.euroneuro.2020.11.011. PMID: 33257116
Individualized differential diagnosis of schizophrenia and mood disorders using neuroanatomical biomarkers.
Koutsouleris N, Meisenzahl EM, Borgwardt S, Riecher-Rössler A, Frodl T, Kambeitz J, Köhler Y, Falkai P, Möller HJ, Reiser M, Davatzikos C
Brain 2015 Jul;138(Pt 7):2059-73. Epub 2015 May 1 doi: 10.1093/brain/awv111. PMID: 25935725Free PMC Article

Recent clinical studies

Etiology

ZO-1 Serum Levels as a Potential Biomarker for Psychotic Disorder.
Aydogan Avşar P, Akkuş M
Clin Neuropharmacol 2024 May-Jun 01;47(3):67-71. doi: 10.1097/WNF.0000000000000590. PMID: 38743599
Psychiatric co-morbidity of drug-resistant epilepsy in Veterans.
Sullivan-Baca E, Rehman R, Towne AR, Haneef Z
Epilepsy Behav 2023 Feb;139:109059. Epub 2022 Dec 26 doi: 10.1016/j.yebeh.2022.109059. PMID: 36577335
Individualized differential diagnosis of schizophrenia and mood disorders using neuroanatomical biomarkers.
Koutsouleris N, Meisenzahl EM, Borgwardt S, Riecher-Rössler A, Frodl T, Kambeitz J, Köhler Y, Falkai P, Möller HJ, Reiser M, Davatzikos C
Brain 2015 Jul;138(Pt 7):2059-73. Epub 2015 May 1 doi: 10.1093/brain/awv111. PMID: 25935725Free PMC Article
Neurocognitive similarities between severe chronic schizophrenia and behavioural variant frontotemporal dementia.
Chan HM, Stolwyk R, Neath J, Kelso W, Walterfang M, Mocellin R, Pantelis C, Velakoulis D
Psychiatry Res 2015 Feb 28;225(3):658-66. Epub 2014 Dec 2 doi: 10.1016/j.psychres.2014.11.029. PMID: 25510904
Transition to schizophrenia in acute and transient psychotic disorders.
Queirazza F, Semple DM, Lawrie SM
Br J Psychiatry 2014;204:299-305. Epub 2013 Dec 19 doi: 10.1192/bjp.bp.113.127340. PMID: 24357576

Diagnosis

Psychiatric co-morbidity of drug-resistant epilepsy in Veterans.
Sullivan-Baca E, Rehman R, Towne AR, Haneef Z
Epilepsy Behav 2023 Feb;139:109059. Epub 2022 Dec 26 doi: 10.1016/j.yebeh.2022.109059. PMID: 36577335
Proposing the short Neurological Evaluation Scale.
Ojagbemi A, Emsley R, Gureje O
Acta Neuropsychiatr 2017 Aug;29(4):236-243. Epub 2016 Oct 24 doi: 10.1017/neu.2016.55. PMID: 27772538
Individualized differential diagnosis of schizophrenia and mood disorders using neuroanatomical biomarkers.
Koutsouleris N, Meisenzahl EM, Borgwardt S, Riecher-Rössler A, Frodl T, Kambeitz J, Köhler Y, Falkai P, Möller HJ, Reiser M, Davatzikos C
Brain 2015 Jul;138(Pt 7):2059-73. Epub 2015 May 1 doi: 10.1093/brain/awv111. PMID: 25935725Free PMC Article
Neurocognitive similarities between severe chronic schizophrenia and behavioural variant frontotemporal dementia.
Chan HM, Stolwyk R, Neath J, Kelso W, Walterfang M, Mocellin R, Pantelis C, Velakoulis D
Psychiatry Res 2015 Feb 28;225(3):658-66. Epub 2014 Dec 2 doi: 10.1016/j.psychres.2014.11.029. PMID: 25510904
Transition to schizophrenia in acute and transient psychotic disorders.
Queirazza F, Semple DM, Lawrie SM
Br J Psychiatry 2014;204:299-305. Epub 2013 Dec 19 doi: 10.1192/bjp.bp.113.127340. PMID: 24357576

Therapy

Spinophilin expression in postmortem prefrontal cortex of schizophrenic subjects: Effects of antipsychotic treatment.
Brocos-Mosquera I, Gabilondo AM, Meana JJ, Callado LF, Erdozain AM
Eur Neuropsychopharmacol 2021 Jan;42:12-21. Epub 2020 Nov 27 doi: 10.1016/j.euroneuro.2020.11.011. PMID: 33257116
Clinical effectiveness of metacognitive training as a transdiagnostic program in routine clinical settings: A prospective, multicenter, single-group study.
Tanoue H, Yoshinaga N, Hayashi Y, Ishikawa R, Ishigaki T, Ishida Y
Jpn J Nurs Sci 2021 Apr;18(2):e12389. Epub 2020 Nov 11 doi: 10.1111/jjns.12389. PMID: 33174673
Long-term safety and effectiveness of lurasidone in schizophrenia: a 22-month, open-label extension study.
Correll CU, Cucchiaro J, Silva R, Hsu J, Pikalov A, Loebel A
CNS Spectr 2016 Oct;21(5):393-402. Epub 2016 Apr 6 doi: 10.1017/S1092852915000917. PMID: 27048911
Clinical pharmacology study of cariprazine (MP-214) in patients with schizophrenia (12-week treatment).
Nakamura T, Kubota T, Iwakaji A, Imada M, Kapás M, Morio Y
Drug Des Devel Ther 2016;10:327-38. Epub 2016 Jan 14 doi: 10.2147/DDDT.S95100. PMID: 26834462Free PMC Article
Nicotine enhances antisaccade performance in schizophrenia patients and healthy controls.
Petrovsky N, Ettinger U, Quednow BB, Landsberg MW, Drees J, Lennertz L, Frommann I, Heilmann K, Sträter B, Kessler H, Dahmen N, Mössner R, Maier W, Wagner M
Int J Neuropsychopharmacol 2013 Aug;16(7):1473-81. Epub 2013 Feb 11 doi: 10.1017/S1461145713000011. PMID: 23399382

Prognosis

Clinical pharmacology study of cariprazine (MP-214) in patients with schizophrenia (12-week treatment).
Nakamura T, Kubota T, Iwakaji A, Imada M, Kapás M, Morio Y
Drug Des Devel Ther 2016;10:327-38. Epub 2016 Jan 14 doi: 10.2147/DDDT.S95100. PMID: 26834462Free PMC Article
FDG-PET scans in patients with Kraepelinian and non-Kraepelinian schizophrenia.
Bralet MC, Buchsbaum MS, DeCastro A, Shihabuddin L, Mitelman SA
Eur Arch Psychiatry Clin Neurosci 2016 Sep;266(6):481-94. Epub 2015 Sep 14 doi: 10.1007/s00406-015-0633-x. PMID: 26370275
Individualized differential diagnosis of schizophrenia and mood disorders using neuroanatomical biomarkers.
Koutsouleris N, Meisenzahl EM, Borgwardt S, Riecher-Rössler A, Frodl T, Kambeitz J, Köhler Y, Falkai P, Möller HJ, Reiser M, Davatzikos C
Brain 2015 Jul;138(Pt 7):2059-73. Epub 2015 May 1 doi: 10.1093/brain/awv111. PMID: 25935725Free PMC Article
Transition to schizophrenia in acute and transient psychotic disorders.
Queirazza F, Semple DM, Lawrie SM
Br J Psychiatry 2014;204:299-305. Epub 2013 Dec 19 doi: 10.1192/bjp.bp.113.127340. PMID: 24357576
Drug attitude and other predictors of medication adherence in schizophrenia: 12 months of electronic monitoring (MEMS(®)) in the Swedish COAST-study.
Brain C, Allerby K, Sameby B, Quinlan P, Joas E, Karilampi U, Lindström E, Eberhard J, Burns T, Waern M
Eur Neuropsychopharmacol 2013 Dec;23(12):1754-62. Epub 2013 Sep 19 doi: 10.1016/j.euroneuro.2013.09.001. PMID: 24091164

Clinical prediction guides

ZO-1 Serum Levels as a Potential Biomarker for Psychotic Disorder.
Aydogan Avşar P, Akkuş M
Clin Neuropharmacol 2024 May-Jun 01;47(3):67-71. doi: 10.1097/WNF.0000000000000590. PMID: 38743599
Spinophilin expression in postmortem prefrontal cortex of schizophrenic subjects: Effects of antipsychotic treatment.
Brocos-Mosquera I, Gabilondo AM, Meana JJ, Callado LF, Erdozain AM
Eur Neuropsychopharmacol 2021 Jan;42:12-21. Epub 2020 Nov 27 doi: 10.1016/j.euroneuro.2020.11.011. PMID: 33257116
Clinical pharmacology study of cariprazine (MP-214) in patients with schizophrenia (12-week treatment).
Nakamura T, Kubota T, Iwakaji A, Imada M, Kapás M, Morio Y
Drug Des Devel Ther 2016;10:327-38. Epub 2016 Jan 14 doi: 10.2147/DDDT.S95100. PMID: 26834462Free PMC Article
Neurocognitive similarities between severe chronic schizophrenia and behavioural variant frontotemporal dementia.
Chan HM, Stolwyk R, Neath J, Kelso W, Walterfang M, Mocellin R, Pantelis C, Velakoulis D
Psychiatry Res 2015 Feb 28;225(3):658-66. Epub 2014 Dec 2 doi: 10.1016/j.psychres.2014.11.029. PMID: 25510904
Transition to schizophrenia in acute and transient psychotic disorders.
Queirazza F, Semple DM, Lawrie SM
Br J Psychiatry 2014;204:299-305. Epub 2013 Dec 19 doi: 10.1192/bjp.bp.113.127340. PMID: 24357576

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