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Coronary heart disease, susceptibility to, 1

MedGen UID:
375884
Concept ID:
C1846418
Disease or Syndrome
Synonym: Coronary heart disease 1
 
Gene (location): CX3CR1 (3p22.2)
 
Monarch Initiative: MONDO:0011817
OMIM®: 607339

Definition

Any coronary artery disease in which the cause of the disease is a mutation in the CX3CR1 gene. [from MONDO]

Professional guidelines

PubMed

Damluji AA, Forman DE, Wang TY, Chikwe J, Kunadian V, Rich MW, Young BA, Page RL 2nd, DeVon HA, Alexander KP; American Heart Association Cardiovascular Disease in Older Populations Committee of the Council on Clinical Cardiology and Council on Cardiovascular and Stroke Nursing; Council on Cardiovascular Radiology and Intervention; and Council on Lifestyle and Cardiometabolic Health
Circulation 2023 Jan 17;147(3):e32-e62. Epub 2022 Dec 12 doi: 10.1161/CIR.0000000000001112. PMID: 36503287Free PMC Article
Gornik HL, Persu A, Adlam D, Aparicio LS, Azizi M, Boulanger M, Bruno RM, de Leeuw P, Fendrikova-Mahlay N, Froehlich J, Ganesh SK, Gray BH, Jamison C, Januszewicz A, Jeunemaitre X, Kadian-Dodov D, Kim ES, Kovacic JC, Mace P, Morganti A, Sharma A, Southerland AM, Touzé E, van der Niepen P, Wang J, Weinberg I, Wilson S, Olin JW, Plouin PF
Vasc Med 2019 Apr;24(2):164-189. Epub 2019 Jan 16 doi: 10.1177/1358863X18821816. PMID: 30648921
Meyers DE, Basha HI, Koenig MK
Tex Heart Inst J 2013;40(4):385-94. PMID: 24082366Free PMC Article

Recent clinical studies

Etiology

Song Z, Wan L, Wang W, Li Y, Zhao Y, Zhuang Z, Dong X, Xiao W, Huang N, Xu M, Clarke R, Qi L, Huang T
Atherosclerosis 2023 Dec;386:117300. Epub 2023 Sep 16 doi: 10.1016/j.atherosclerosis.2023.117300. PMID: 37813749
Luo J, le Cessie S, van Heemst D, Noordam R
J Am Coll Cardiol 2021 Jan 5;77(1):45-54. doi: 10.1016/j.jacc.2020.10.048. PMID: 33413940
Jaiswal S, Natarajan P, Silver AJ, Gibson CJ, Bick AG, Shvartz E, McConkey M, Gupta N, Gabriel S, Ardissino D, Baber U, Mehran R, Fuster V, Danesh J, Frossard P, Saleheen D, Melander O, Sukhova GK, Neuberg D, Libby P, Kathiresan S, Ebert BL
N Engl J Med 2017 Jul 13;377(2):111-121. Epub 2017 Jun 21 doi: 10.1056/NEJMoa1701719. PMID: 28636844Free PMC Article
Holmes MV, Ala-Korpela M, Smith GD
Nat Rev Cardiol 2017 Oct;14(10):577-590. Epub 2017 Jun 1 doi: 10.1038/nrcardio.2017.78. PMID: 28569269Free PMC Article
Khera AV, Emdin CA, Drake I, Natarajan P, Bick AG, Cook NR, Chasman DI, Baber U, Mehran R, Rader DJ, Fuster V, Boerwinkle E, Melander O, Orho-Melander M, Ridker PM, Kathiresan S
N Engl J Med 2016 Dec 15;375(24):2349-2358. Epub 2016 Nov 13 doi: 10.1056/NEJMoa1605086. PMID: 27959714Free PMC Article

Diagnosis

Song Z, Wan L, Wang W, Li Y, Zhao Y, Zhuang Z, Dong X, Xiao W, Huang N, Xu M, Clarke R, Qi L, Huang T
Atherosclerosis 2023 Dec;386:117300. Epub 2023 Sep 16 doi: 10.1016/j.atherosclerosis.2023.117300. PMID: 37813749
Gan T, Hu J, Liu W, Li C, Xu Q, Wang Y, Lu S, Aledan AKO, Wang Y, Wang Z
J Am Heart Assoc 2023 Jun 20;12(12):e029689. Epub 2023 Jun 10 doi: 10.1161/JAHA.123.029689. PMID: 37301769Free PMC Article
Zagkos L, Dib MJ, Pinto R, Gill D, Koskeridis F, Drenos F, Markozannes G, Elliott P, Zuber V, Tsilidis K, Dehghan A, Tzoulaki I
PLoS Med 2022 Dec;19(12):e1004141. Epub 2022 Dec 29 doi: 10.1371/journal.pmed.1004141. PMID: 36580444Free PMC Article
Hasbani NR, Ligthart S, Brown MR, Heath AS, Bebo A, Ashley KE, Boerwinkle E, Morrison AC, Folsom AR, Aguilar D, de Vries PS
Circulation 2022 Mar 15;145(11):808-818. Epub 2022 Jan 31 doi: 10.1161/CIRCULATIONAHA.121.053730. PMID: 35094551Free PMC Article
Richardson TG, Sanderson E, Palmer TM, Ala-Korpela M, Ference BA, Davey Smith G, Holmes MV
PLoS Med 2020 Mar;17(3):e1003062. Epub 2020 Mar 23 doi: 10.1371/journal.pmed.1003062. PMID: 32203549Free PMC Article

Therapy

Gan T, Hu J, Liu W, Li C, Xu Q, Wang Y, Lu S, Aledan AKO, Wang Y, Wang Z
J Am Heart Assoc 2023 Jun 20;12(12):e029689. Epub 2023 Jun 10 doi: 10.1161/JAHA.123.029689. PMID: 37301769Free PMC Article
Luo J, le Cessie S, van Heemst D, Noordam R
J Am Coll Cardiol 2021 Jan 5;77(1):45-54. doi: 10.1016/j.jacc.2020.10.048. PMID: 33413940
Richardson TG, Sanderson E, Palmer TM, Ala-Korpela M, Ference BA, Davey Smith G, Holmes MV
PLoS Med 2020 Mar;17(3):e1003062. Epub 2020 Mar 23 doi: 10.1371/journal.pmed.1003062. PMID: 32203549Free PMC Article
Daghlas I, Dashti HS, Lane J, Aragam KG, Rutter MK, Saxena R, Vetter C
J Am Coll Cardiol 2019 Sep 10;74(10):1304-1314. doi: 10.1016/j.jacc.2019.07.022. PMID: 31488267Free PMC Article
Holmes MV, Ala-Korpela M, Smith GD
Nat Rev Cardiol 2017 Oct;14(10):577-590. Epub 2017 Jun 1 doi: 10.1038/nrcardio.2017.78. PMID: 28569269Free PMC Article

Prognosis

Gan T, Hu J, Liu W, Li C, Xu Q, Wang Y, Lu S, Aledan AKO, Wang Y, Wang Z
J Am Heart Assoc 2023 Jun 20;12(12):e029689. Epub 2023 Jun 10 doi: 10.1161/JAHA.123.029689. PMID: 37301769Free PMC Article
Luo J, le Cessie S, van Heemst D, Noordam R
J Am Coll Cardiol 2021 Jan 5;77(1):45-54. doi: 10.1016/j.jacc.2020.10.048. PMID: 33413940
Fan M, Sun D, Zhou T, Heianza Y, Lv J, Li L, Qi L
Eur Heart J 2020 Mar 14;41(11):1182-1189. doi: 10.1093/eurheartj/ehz849. PMID: 31848595Free PMC Article
Said MA, Verweij N, van der Harst P
JAMA Cardiol 2018 Aug 1;3(8):693-702. doi: 10.1001/jamacardio.2018.1717. PMID: 29955826Free PMC Article
Khera AV, Emdin CA, Drake I, Natarajan P, Bick AG, Cook NR, Chasman DI, Baber U, Mehran R, Rader DJ, Fuster V, Boerwinkle E, Melander O, Orho-Melander M, Ridker PM, Kathiresan S
N Engl J Med 2016 Dec 15;375(24):2349-2358. Epub 2016 Nov 13 doi: 10.1056/NEJMoa1605086. PMID: 27959714Free PMC Article

Clinical prediction guides

Song Z, Wan L, Wang W, Li Y, Zhao Y, Zhuang Z, Dong X, Xiao W, Huang N, Xu M, Clarke R, Qi L, Huang T
Atherosclerosis 2023 Dec;386:117300. Epub 2023 Sep 16 doi: 10.1016/j.atherosclerosis.2023.117300. PMID: 37813749
Tao S, Tang X, Yu L, Li L, Zhang G, Zhang L, Huang L, Wu J
Eur J Med Res 2023 Sep 1;28(1):311. doi: 10.1186/s40001-023-01220-5. PMID: 37658418Free PMC Article
Gan T, Hu J, Liu W, Li C, Xu Q, Wang Y, Lu S, Aledan AKO, Wang Y, Wang Z
J Am Heart Assoc 2023 Jun 20;12(12):e029689. Epub 2023 Jun 10 doi: 10.1161/JAHA.123.029689. PMID: 37301769Free PMC Article
Luo J, le Cessie S, van Heemst D, Noordam R
J Am Coll Cardiol 2021 Jan 5;77(1):45-54. doi: 10.1016/j.jacc.2020.10.048. PMID: 33413940
Khera AV, Emdin CA, Drake I, Natarajan P, Bick AG, Cook NR, Chasman DI, Baber U, Mehran R, Rader DJ, Fuster V, Boerwinkle E, Melander O, Orho-Melander M, Ridker PM, Kathiresan S
N Engl J Med 2016 Dec 15;375(24):2349-2358. Epub 2016 Nov 13 doi: 10.1056/NEJMoa1605086. PMID: 27959714Free PMC Article

Recent systematic reviews

Gill D, Cameron AC, Burgess S, Li X, Doherty DJ, Karhunen V, Abdul-Rahim AH, Taylor-Rowan M, Zuber V, Tsao PS, Klarin D; VA Million Veteran Program, Evangelou E, Elliott P, Damrauer SM, Quinn TJ, Dehghan A, Theodoratou E, Dawson J, Tzoulaki I
Hypertension 2021 Feb;77(2):383-392. Epub 2020 Dec 28 doi: 10.1161/HYPERTENSIONAHA.120.16547. PMID: 33356394Free PMC Article
Ma R, Zhu X, Yan B
Gene 2018 Dec 15;678:280-287. Epub 2018 Aug 10 doi: 10.1016/j.gene.2018.08.024. PMID: 30103009
Du Y, Zhang G, Liu Z
Virol J 2018 Feb 6;15(1):31. doi: 10.1186/s12985-018-0937-3. PMID: 29409508Free PMC Article
Fernández-Sanlés A, Sayols-Baixeras S, Subirana I, Degano IR, Elosua R
Atherosclerosis 2017 Aug;263:325-333. Epub 2017 May 18 doi: 10.1016/j.atherosclerosis.2017.05.022. PMID: 28577936
Song C, Burgess S, Eicher JD, O'Donnell CJ, Johnson AD
J Am Heart Assoc 2017 May 26;6(6) doi: 10.1161/JAHA.116.004918. PMID: 28550093Free PMC Article

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