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Therapy-Related Leukemia

MedGen UID:
414619
Concept ID:
C2825306
Neoplastic Process
Synonym: Therapy Related Leukemia

Definition

A leukemia arising as a result of the mutagenic effect of chemotherapy agents that are used for the treatment of a malignant tumor or exposure to ionizing radiation. [from NCI]

Professional guidelines

PubMed

Lomov NA, Viushkov VS, Rubtsov MA
Biochemistry (Mosc) 2023 Jul;88(7):892-911. doi: 10.1134/S0006297923070040. PMID: 37751862
Rund D, Ben-Yehuda D
Hematology 2004 Jun;9(3):179-87. doi: 10.1080/10245330410001701503. PMID: 15204099
Kantarjian HM, Estey EH, Keating MJ
Hematol Oncol Clin North Am 1993 Feb;7(1):81-107. PMID: 7680643

Recent clinical studies

Etiology

Ali Hailan YM, Al-Dubai HN, Yassin MA
Oncology 2023;101(6):362-368. Epub 2023 May 9 doi: 10.1159/000530463. PMID: 37231874
Imamura T, Taga T, Takagi M, Kawasaki H, Koh K, Taki T, Adachi S, Manabe A, Ishida Y; Leukemia/Lymphoma Committee; Japanese Society of Pediatric Hematology Oncology (JSPHO)
Int J Hematol 2018 Jul;108(1):91-97. Epub 2018 Mar 24 doi: 10.1007/s12185-018-2439-x. PMID: 29574603
Bhatia S
Semin Oncol 2013 Dec;40(6):666-75. doi: 10.1053/j.seminoncol.2013.09.013. PMID: 24331189Free PMC Article
Rund D, Ben-Yehuda D
Hematology 2004 Jun;9(3):179-87. doi: 10.1080/10245330410001701503. PMID: 15204099
Davies SM
Med Pediatr Oncol 2001 May;36(5):536-40. doi: 10.1002/mpo.1126. PMID: 11340608

Diagnosis

Imamura T, Taga T, Takagi M, Kawasaki H, Koh K, Taki T, Adachi S, Manabe A, Ishida Y; Leukemia/Lymphoma Committee; Japanese Society of Pediatric Hematology Oncology (JSPHO)
Int J Hematol 2018 Jul;108(1):91-97. Epub 2018 Mar 24 doi: 10.1007/s12185-018-2439-x. PMID: 29574603
Zhang L, Samad A, Pombo-de-Oliveira MS, Scelo G, Smith MT, Feusner J, Wiemels JL, Metayer C
Blood Rev 2015 Mar;29(2):101-25. Epub 2014 Sep 30 doi: 10.1016/j.blre.2014.09.013. PMID: 25445717Free PMC Article
Casorelli I, Bossa C, Bignami M
Int J Environ Res Public Health 2012 Aug;9(8):2636-57. Epub 2012 Jul 27 doi: 10.3390/ijerph9082636. PMID: 23066388Free PMC Article
Giles FJ, Koeffler HP
Curr Opin Hematol 1994 Jul;1(4):256-60. PMID: 9371291
Foucar K, McKenna RW, Bloomfield CD, Bowers TK, Brunning RD
Cancer 1979 Apr;43(4):1285-96. doi: 10.1002/1097-0142(197904)43:4<1285::aid-cncr2820430416>3.0.co;2-j. PMID: 445330

Therapy

Gale RP, Hlatky L, Sachs RK, Radivoyevitch T
Leuk Res 2014 Oct;38(10):1162-4. Epub 2014 Aug 11 doi: 10.1016/j.leukres.2014.08.002. PMID: 25175829
Bhatia S
Semin Oncol 2013 Dec;40(6):666-75. doi: 10.1053/j.seminoncol.2013.09.013. PMID: 24331189Free PMC Article
Cowell IG, Austin CA
Int J Environ Res Public Health 2012 Jun;9(6):2075-91. Epub 2012 May 31 doi: 10.3390/ijerph9062075. PMID: 22829791Free PMC Article
Rund D, Ben-Yehuda D
Hematology 2004 Jun;9(3):179-87. doi: 10.1080/10245330410001701503. PMID: 15204099
Thirman MJ, Larson RA
Hematol Oncol Clin North Am 1996 Apr;10(2):293-320. doi: 10.1016/s0889-8588(05)70340-3. PMID: 8707757

Prognosis

Imamura T, Taga T, Takagi M, Kawasaki H, Koh K, Taki T, Adachi S, Manabe A, Ishida Y; Leukemia/Lymphoma Committee; Japanese Society of Pediatric Hematology Oncology (JSPHO)
Int J Hematol 2018 Jul;108(1):91-97. Epub 2018 Mar 24 doi: 10.1007/s12185-018-2439-x. PMID: 29574603
Zhang L, Samad A, Pombo-de-Oliveira MS, Scelo G, Smith MT, Feusner J, Wiemels JL, Metayer C
Blood Rev 2015 Mar;29(2):101-25. Epub 2014 Sep 30 doi: 10.1016/j.blre.2014.09.013. PMID: 25445717Free PMC Article
Bhatia S
Semin Oncol 2013 Dec;40(6):666-75. doi: 10.1053/j.seminoncol.2013.09.013. PMID: 24331189Free PMC Article
Rund D, Ben-Yehuda D
Hematology 2004 Jun;9(3):179-87. doi: 10.1080/10245330410001701503. PMID: 15204099
Park S, Picard F, Dreyfus F
Leukemia 2002 Aug;16(8):1399-401. doi: 10.1038/sj.leu.2402549. PMID: 12145675

Clinical prediction guides

Spitzer B, Rutherford KD, Gundem G, McGovern EM, Millard NE, Arango Ossa JE, Cheung IY, Gao T, Levine MF, Zhang Y, Medina-Martínez JS, Feng Y, Ptashkin RN, Bolton KL, Farnoud N, Zhou Y, Patel MA, Asimomitis G, Cobbs CC, Mohibullah N, Huberman KH, Arcilla ME, Kushner BH, Modak S, Kung AL, Zehir A, Levine RL, Armstrong SA, Cheung NKV, Papaemmanuil E
Clin Cancer Res 2022 Apr 14;28(8):1614-1627. doi: 10.1158/1078-0432.CCR-21-2451. PMID: 35078859Free PMC Article
Zhang L, Samad A, Pombo-de-Oliveira MS, Scelo G, Smith MT, Feusner J, Wiemels JL, Metayer C
Blood Rev 2015 Mar;29(2):101-25. Epub 2014 Sep 30 doi: 10.1016/j.blre.2014.09.013. PMID: 25445717Free PMC Article
Bhatia S
Semin Oncol 2013 Dec;40(6):666-75. doi: 10.1053/j.seminoncol.2013.09.013. PMID: 24331189Free PMC Article
Rund D, Ben-Yehuda D
Hematology 2004 Jun;9(3):179-87. doi: 10.1080/10245330410001701503. PMID: 15204099
Giles FJ, Koeffler HP
Curr Opin Hematol 1994 Jul;1(4):256-60. PMID: 9371291

Recent systematic reviews

Ali Hailan YM, Al-Dubai HN, Yassin MA
Oncology 2023;101(6):362-368. Epub 2023 May 9 doi: 10.1159/000530463. PMID: 37231874

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