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Dizziness

MedGen UID:
4360
•Concept ID:
C0012833
•
Sign or Symptom
Synonym: Dizzyness
SNOMED CT: Dizziness (404640003); Dizzy (404640003)

Definition

A sensation of lightheadedness, unsteadiness, turning, spinning or rocking. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDizziness

Professional guidelines

PubMed

Benign paroxysmal positional vertigo: Effective diagnosis and treatment.
Cole SR, Honaker JA
Cleve Clin J Med 2022 Nov 1;89(11):653-662. doi: 10.3949/ccjm.89a.21057. PMID: 36319052
Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.
Wilkins T, Wheeler B, Carpenter M
Am Fam Physician 2020 Mar 1;101(5):294-300. PMID: 32109037
Clinical Practice Guideline: Benign Paroxysmal Positional Vertigo (Update).
Bhattacharyya N, Gubbels SP, Schwartz SR, Edlow JA, El-Kashlan H, Fife T, Holmberg JM, Mahoney K, Hollingsworth DB, Roberts R, Seidman MD, Steiner RW, Do BT, Voelker CC, Waguespack RW, Corrigan MD
Otolaryngol Head Neck Surg 2017 Mar;156(3_suppl):S1-S47. doi: 10.1177/0194599816689667. PMID: 28248609

Recent clinical studies

Etiology

Effects of vestibular rehabilitation therapy versus virtual reality on balance, dizziness, and gait in patients with subacute stroke: A randomized controlled trial.
Sana V, Ghous M, Kashif M, Albalwi A, Muneer R, Zia M
Medicine (Baltimore) 2023 Jun 16;102(24):e33203. doi: 10.1097/MD.0000000000033203. PMID: 37327306Free PMC Article
Vascular vertigo and dizziness: Diagnostic criteria.
Kim JS, Newman-Toker DE, Kerber KA, Jahn K, Bertholon P, Waterston J, Lee H, Bisdorff A, Strupp M
J Vestib Res 2022;32(3):205-222. doi: 10.3233/VES-210169. PMID: 35367974Free PMC Article
Cerebellar Dizziness and Vertigo: Etiologies, Diagnostic Assessment, and Treatment.
Zwergal A, Feil K, Schniepp R, Strupp M
Semin Neurol 2020 Feb;40(1):87-96. Epub 2019 Dec 30 doi: 10.1055/s-0039-3400315. PMID: 31887755
Diagnostic criteria for persistent postural-perceptual dizziness (PPPD): Consensus document of the committee for the Classification of Vestibular Disorders of the Bárány Society.
Staab JP, Eckhardt-Henn A, Horii A, Jacob R, Strupp M, Brandt T, Bronstein A
J Vestib Res 2017;27(4):191-208. doi: 10.3233/VES-170622. PMID: 29036855Free PMC Article
The epidemiology of dizziness and vertigo.
Neuhauser HK
Handb Clin Neurol 2016;137:67-82. doi: 10.1016/B978-0-444-63437-5.00005-4. PMID: 27638063

Diagnosis

Dizziness: Evaluation and Management.
Rogers TS, Noel MA, Garcia B
Am Fam Physician 2023 May;107(5):514-523. PMID: 37192077
Suboccipital Muscles, Forward Head Posture, and Cervicogenic Dizziness.
Sung YH
Medicina (Kaunas) 2022 Dec 5;58(12) doi: 10.3390/medicina58121791. PMID: 36556992Free PMC Article
Vascular vertigo and dizziness: Diagnostic criteria.
Kim JS, Newman-Toker DE, Kerber KA, Jahn K, Bertholon P, Waterston J, Lee H, Bisdorff A, Strupp M
J Vestib Res 2022;32(3):205-222. doi: 10.3233/VES-210169. PMID: 35367974Free PMC Article
Persistent Postural-Perceptual Dizziness.
Staab JP
Semin Neurol 2020 Feb;40(1):130-137. Epub 2020 Jan 14 doi: 10.1055/s-0039-3402736. PMID: 31935771
Persistent postural-perceptual dizziness (PPPD): a common, characteristic and treatable cause of chronic dizziness.
Popkirov S, Staab JP, Stone J
Pract Neurol 2018 Feb;18(1):5-13. Epub 2017 Dec 5 doi: 10.1136/practneurol-2017-001809. PMID: 29208729

Therapy

Vestibular Disorders.
Strupp M, Dlugaiczyk J, Ertl-Wagner BB, Rujescu D, Westhofen M, Dieterich M
Dtsch Arztebl Int 2020 Apr 24;117(17):300-310. doi: 10.3238/arztebl.2020.0300. PMID: 32530417Free PMC Article
Gepirone hydrochloride: a novel antidepressant with 5-HT1A agonistic properties.
Kaur Gill A, Bansal Y, Bhandari R, Kaur S, Kaur J, Singh R, Kuhad A, Kuhad A
Drugs Today (Barc) 2019 Jul;55(7):423-437. doi: 10.1358/dot.2019.55.7.2958474. PMID: 31347611
Treatment of fatigue in amyotrophic lateral sclerosis/motor neuron disease.
Gibbons C, Pagnini F, Friede T, Young CA
Cochrane Database Syst Rev 2018 Jan 2;1(1):CD011005. doi: 10.1002/14651858.CD011005.pub2. PMID: 29293261Free PMC Article
Flibanserin.
Vallejos X, Wu C
J Pharm Pract 2017 Apr;30(2):256-260. Epub 2016 Jul 9 doi: 10.1177/0897190016630409. PMID: 26873507
The Safety of Melatonin in Humans.
Andersen LP, Gögenur I, Rosenberg J, Reiter RJ
Clin Drug Investig 2016 Mar;36(3):169-75. doi: 10.1007/s40261-015-0368-5. PMID: 26692007

Prognosis

Effectiveness of conventional versus virtual reality-based vestibular rehabilitation exercises in elderly patients with dizziness: a randomized controlled study with 6-month follow-up.
Kanyılmaz T, Topuz O, Ardıç FN, Alkan H, Öztekin SNS, Topuz B, Ardıç F
Braz J Otorhinolaryngol 2022 Nov-Dec;88 Suppl 3(Suppl 3):S41-S49. Epub 2021 Oct 26 doi: 10.1016/j.bjorl.2021.08.010. PMID: 34799265Free PMC Article
Adverse reactions to radiopharmaceuticals.
Pérez-Iruela JA, Pastor-Fructuoso P, De Gracia-Rodríguez C, Soler-Vigil M, Gómez-Martínez MDV
Farm Hosp 2021 Mar 30;45(3):142-149. doi: 10.7399/fh.11669. PMID: 33941058
Autonomic dysfunction in 'long COVID': rationale, physiology and management strategies.
Dani M, Dirksen A, Taraborrelli P, Torocastro M, Panagopoulos D, Sutton R, Lim PB
Clin Med (Lond) 2021 Jan;21(1):e63-e67. Epub 2020 Nov 26 doi: 10.7861/clinmed.2020-0896. PMID: 33243837Free PMC Article
Seated postural hypotension.
Gorelik O, Cohen N
J Am Soc Hypertens 2015 Dec;9(12):985-92. Epub 2015 Oct 9 doi: 10.1016/j.jash.2015.10.001. PMID: 26515671
The tramadol option.
Desmeules JA
Eur J Pain 2000;4 Suppl A:15-21. PMID: 11310478

Clinical prediction guides

Effect of betahistine treatment on dizziness and anxiety symptoms of BPPV patients.
Erdur ZB, Evran N
Niger J Clin Pract 2023 Sep;26(9):1383-1387. doi: 10.4103/njcp.njcp_305_23. PMID: 37794554
Development and Validation of the Modified Motion Sensitivity Test.
Heusel-Gillig L, Santucci V, Hall CD
Otol Neurotol 2022 Sep 1;43(8):944-949. doi: 10.1097/MAO.0000000000003641. PMID: 35970158
Betahistine add-on therapy for treatment of subjects with posterior benign paroxysmal positional vertigo: a randomized controlled trial.
Sayin I, Koç RH, Temirbekov D, Gunes S, Cirak M, Yazici ZM
Braz J Otorhinolaryngol 2022 May-Jun;88(3):421-426. Epub 2020 Sep 12 doi: 10.1016/j.bjorl.2020.07.011. PMID: 32978116Free PMC Article
Efficacy of Epley Maneuver on Quality of Life of Elderly Patients with Subjective BPPV.
Uz U, Uz D, Akdal G, Çelik O
J Int Adv Otol 2019 Dec;15(3):420-424. doi: 10.5152/iao.2019.6483. PMID: 31846923Free PMC Article
Use of HINTS in the acute vestibular syndrome. An Overview.
Kattah JC
Stroke Vasc Neurol 2018 Dec;3(4):190-196. Epub 2018 Jun 23 doi: 10.1136/svn-2018-000160. PMID: 30637123Free PMC Article

Recent systematic reviews

Cannabis-Based Products for Chronic Pain : A Systematic Review.
McDonagh MS, Morasco BJ, Wagner J, Ahmed AY, Fu R, Kansagara D, Chou R
Ann Intern Med 2022 Aug;175(8):1143-1153. Epub 2022 Jun 7 doi: 10.7326/M21-4520. PMID: 35667066
Systematic review and meta-analysis of the therapeutic management of patients with cervicogenic dizziness.
De Vestel C, Vereeck L, Reid SA, Van Rompaey V, Lemmens J, De Hertogh W
J Man Manip Ther 2022 Oct;30(5):273-283. Epub 2022 Apr 6 doi: 10.1080/10669817.2022.2033044. PMID: 35383538Free PMC Article
Hearing Loss, Tinnitus, and Dizziness in COVID-19: A Systematic Review and Meta-Analysis.
Jafari Z, Kolb BE, Mohajerani MH
Can J Neurol Sci 2022 Mar;49(2):184-195. Epub 2021 Apr 12 doi: 10.1017/cjn.2021.63. PMID: 33843530Free PMC Article
Effects of virtual reality rehabilitation training on gait and balance in patients with Parkinson's disease: A systematic review.
Lei C, Sunzi K, Dai F, Liu X, Wang Y, Zhang B, He L, Ju M
PLoS One 2019;14(11):e0224819. Epub 2019 Nov 7 doi: 10.1371/journal.pone.0224819. PMID: 31697777Free PMC Article
Pregabalin for neuropathic pain in adults.
Derry S, Bell RF, Straube S, Wiffen PJ, Aldington D, Moore RA
Cochrane Database Syst Rev 2019 Jan 23;1(1):CD007076. doi: 10.1002/14651858.CD007076.pub3. PMID: 30673120Free PMC Article

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