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Metastatic Breast Lobular Carcinoma

MedGen UID:
437465
•Concept ID:
C2698204
•
Neoplastic Process
Synonym: Metastatic Lobular Breast Carcinoma

Definition

A lobular breast carcinoma that has spread from the original site of growth to another anatomic site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Breast Lobular Carcinoma

Professional guidelines

PubMed

Therapeutic potential of [(177)Lu]Lu-DOTAGA-FAPi dimers in metastatic breast cancer patients with limited treatment options: efficacy and safety assessment.
Yadav MP, Ballal S, Martin M, Roesch F, Satapathy S, Moon ES, Tripathi M, Gogia A, Bal C
Eur J Nucl Med Mol Imaging 2024 Feb;51(3):805-819. Epub 2023 Nov 7 doi: 10.1007/s00259-023-06482-z. PMID: 37932560
Current and future diagnostic and treatment strategies for patients with invasive lobular breast cancer.
Van Baelen K, Geukens T, Maetens M, Tjan-Heijnen V, Lord CJ, Linn S, Bidard FC, Richard F, Yang WW, Steele RE, Pettitt SJ, Van Ongeval C, De Schepper M, Isnaldi E, Nevelsteen I, Smeets A, Punie K, Voorwerk L, Wildiers H, Floris G, Vincent-Salomon A, Derksen PWB, Neven P, Senkus E, Sawyer E, Kok M, Desmedt C
Ann Oncol 2022 Aug;33(8):769-785. Epub 2022 May 21 doi: 10.1016/j.annonc.2022.05.006. PMID: 35605746
Treatment of breast cancer.
Maughan KL, Lutterbie MA, Ham PS
Am Fam Physician 2010 Jun 1;81(11):1339-46. PMID: 20521754

Recent clinical studies

Etiology

Current and future diagnostic and treatment strategies for patients with invasive lobular breast cancer.
Van Baelen K, Geukens T, Maetens M, Tjan-Heijnen V, Lord CJ, Linn S, Bidard FC, Richard F, Yang WW, Steele RE, Pettitt SJ, Van Ongeval C, De Schepper M, Isnaldi E, Nevelsteen I, Smeets A, Punie K, Voorwerk L, Wildiers H, Floris G, Vincent-Salomon A, Derksen PWB, Neven P, Senkus E, Sawyer E, Kok M, Desmedt C
Ann Oncol 2022 Aug;33(8):769-785. Epub 2022 May 21 doi: 10.1016/j.annonc.2022.05.006. PMID: 35605746
Randomized Trial Comparing Resection of Primary Tumor with No Surgery in Stage IV Breast Cancer at Presentation: Protocol MF07-01.
Soran A, Ozmen V, Ozbas S, Karanlik H, Muslumanoglu M, Igci A, Canturk Z, Utkan Z, Ozaslan C, Evrensel T, Uras C, Aksaz E, Soyder A, Ugurlu U, Col C, Cabioglu N, Bozkurt B, Uzunkoy A, Koksal N, Gulluoglu BM, Unal B, Atalay C, Yıldırım E, Erdem E, Salimoglu S, Sezer A, Koyuncu A, Gurleyik G, Alagol H, Ulufi N, Berberoglu U, Dulger M, Cengiz O, Sezgin E, Johnson R
Ann Surg Oncol 2018 Oct;25(11):3141-3149. Epub 2018 May 17 doi: 10.1245/s10434-018-6494-6. PMID: 29777404
Radiotherapy in patients with distant metastatic breast cancer.
Steinauer K, Gross MW, Huang DJ, Eppenberger-Castori S, Güth U
Radiat Oncol 2014 May 30;9:126. doi: 10.1186/1748-717X-9-126. PMID: 24885766Free PMC Article
Prolonged survival of patients with breast cancer-related leptomeningeal metastases.
Le Rhun E, Taillibert S, Zairi F, Pannier D, Boulanger T, Andre C, Cazin JL, Dubois F, Bonneterre J, Chamberlain MC
Anticancer Res 2013 May;33(5):2057-63. PMID: 23645756
MRI-guided needle localization: technique.
DeAngelis GA, Moran RE, Fajardo LL, Mugler JP, Christopher JM, Harvey JA
Semin Ultrasound CT MR 2000 Oct;21(5):337-50. doi: 10.1016/s0887-2171(00)90028-3. PMID: 11071615

Diagnosis

Current and future diagnostic and treatment strategies for patients with invasive lobular breast cancer.
Van Baelen K, Geukens T, Maetens M, Tjan-Heijnen V, Lord CJ, Linn S, Bidard FC, Richard F, Yang WW, Steele RE, Pettitt SJ, Van Ongeval C, De Schepper M, Isnaldi E, Nevelsteen I, Smeets A, Punie K, Voorwerk L, Wildiers H, Floris G, Vincent-Salomon A, Derksen PWB, Neven P, Senkus E, Sawyer E, Kok M, Desmedt C
Ann Oncol 2022 Aug;33(8):769-785. Epub 2022 May 21 doi: 10.1016/j.annonc.2022.05.006. PMID: 35605746
Unexpected finding.
Vallianou NG, Stavrinou N, Panagopoulos F, Geladari E, Sykaras AG, Vourlakou C
J Clin Pathol 2021 Apr;74(4):e6. Epub 2020 Oct 13 doi: 10.1136/jclinpath-2020-206770. PMID: 33051289
Randomized Trial Comparing Resection of Primary Tumor with No Surgery in Stage IV Breast Cancer at Presentation: Protocol MF07-01.
Soran A, Ozmen V, Ozbas S, Karanlik H, Muslumanoglu M, Igci A, Canturk Z, Utkan Z, Ozaslan C, Evrensel T, Uras C, Aksaz E, Soyder A, Ugurlu U, Col C, Cabioglu N, Bozkurt B, Uzunkoy A, Koksal N, Gulluoglu BM, Unal B, Atalay C, Yıldırım E, Erdem E, Salimoglu S, Sezer A, Koyuncu A, Gurleyik G, Alagol H, Ulufi N, Berberoglu U, Dulger M, Cengiz O, Sezgin E, Johnson R
Ann Surg Oncol 2018 Oct;25(11):3141-3149. Epub 2018 May 17 doi: 10.1245/s10434-018-6494-6. PMID: 29777404
Carcinoma en cuirasse.
Alani A, Roberts G, Kerr O
BMJ Case Rep 2017 Dec 2;2017 doi: 10.1136/bcr-2017-222121. PMID: 29197843Free PMC Article
Relapse of invasive lobular carcinoma.
Mallon E, Varga Z
Breast Dis 2008-2009;30:53-6. doi: 10.3233/BD-2009-0284. PMID: 19850996

Therapy

Current and future diagnostic and treatment strategies for patients with invasive lobular breast cancer.
Van Baelen K, Geukens T, Maetens M, Tjan-Heijnen V, Lord CJ, Linn S, Bidard FC, Richard F, Yang WW, Steele RE, Pettitt SJ, Van Ongeval C, De Schepper M, Isnaldi E, Nevelsteen I, Smeets A, Punie K, Voorwerk L, Wildiers H, Floris G, Vincent-Salomon A, Derksen PWB, Neven P, Senkus E, Sawyer E, Kok M, Desmedt C
Ann Oncol 2022 Aug;33(8):769-785. Epub 2022 May 21 doi: 10.1016/j.annonc.2022.05.006. PMID: 35605746
Randomized Trial Comparing Resection of Primary Tumor with No Surgery in Stage IV Breast Cancer at Presentation: Protocol MF07-01.
Soran A, Ozmen V, Ozbas S, Karanlik H, Muslumanoglu M, Igci A, Canturk Z, Utkan Z, Ozaslan C, Evrensel T, Uras C, Aksaz E, Soyder A, Ugurlu U, Col C, Cabioglu N, Bozkurt B, Uzunkoy A, Koksal N, Gulluoglu BM, Unal B, Atalay C, Yıldırım E, Erdem E, Salimoglu S, Sezer A, Koyuncu A, Gurleyik G, Alagol H, Ulufi N, Berberoglu U, Dulger M, Cengiz O, Sezgin E, Johnson R
Ann Surg Oncol 2018 Oct;25(11):3141-3149. Epub 2018 May 17 doi: 10.1245/s10434-018-6494-6. PMID: 29777404
What common biomarkers characterize a triple-negative profile in breast cancer?
Kallel I, Rebaï M, Khabir A, Rebaï A
Pathol Biol (Paris) 2015 Sep;63(4-5):224-9. Epub 2015 Aug 20 doi: 10.1016/j.patbio.2015.07.005. PMID: 26300241
Sentinel-lymph-node biopsy in patients with breast cancer before and after neoadjuvant chemotherapy (SENTINA): a prospective, multicentre cohort study.
Kuehn T, Bauerfeind I, Fehm T, Fleige B, Hausschild M, Helms G, Lebeau A, Liedtke C, von Minckwitz G, Nekljudova V, Schmatloch S, Schrenk P, Staebler A, Untch M
Lancet Oncol 2013 Jun;14(7):609-18. Epub 2013 May 15 doi: 10.1016/S1470-2045(13)70166-9. PMID: 23683750
Treatment of breast cancer.
Maughan KL, Lutterbie MA, Ham PS
Am Fam Physician 2010 Jun 1;81(11):1339-46. PMID: 20521754

Prognosis

Rectal Metastases of Breast Carcinoma: A Case Report.
Fontes EVLC, Silva NA, Santos LAMD, Santos VMD
Arch Iran Med 2021 Feb 1;24(2):125-128. doi: 10.34172/aim.2021.19. PMID: 33636980
Unexpected finding.
Vallianou NG, Stavrinou N, Panagopoulos F, Geladari E, Sykaras AG, Vourlakou C
J Clin Pathol 2021 Apr;74(4):e6. Epub 2020 Oct 13 doi: 10.1136/jclinpath-2020-206770. PMID: 33051289
Randomized Trial Comparing Resection of Primary Tumor with No Surgery in Stage IV Breast Cancer at Presentation: Protocol MF07-01.
Soran A, Ozmen V, Ozbas S, Karanlik H, Muslumanoglu M, Igci A, Canturk Z, Utkan Z, Ozaslan C, Evrensel T, Uras C, Aksaz E, Soyder A, Ugurlu U, Col C, Cabioglu N, Bozkurt B, Uzunkoy A, Koksal N, Gulluoglu BM, Unal B, Atalay C, Yıldırım E, Erdem E, Salimoglu S, Sezer A, Koyuncu A, Gurleyik G, Alagol H, Ulufi N, Berberoglu U, Dulger M, Cengiz O, Sezgin E, Johnson R
Ann Surg Oncol 2018 Oct;25(11):3141-3149. Epub 2018 May 17 doi: 10.1245/s10434-018-6494-6. PMID: 29777404
Eight-year follow up result of the OTOASOR trial: The Optimal Treatment Of the Axilla - Surgery Or Radiotherapy after positive sentinel lymph node biopsy in early-stage breast cancer: A randomized, single centre, phase III, non-inferiority trial.
Sávolt Á, Péley G, Polgár C, Udvarhelyi N, Rubovszky G, Kovács E, Győrffy B, Kásler M, Mátrai Z
Eur J Surg Oncol 2017 Apr;43(4):672-679. Epub 2017 Jan 16 doi: 10.1016/j.ejso.2016.12.011. PMID: 28139362
Radiotherapy in patients with distant metastatic breast cancer.
Steinauer K, Gross MW, Huang DJ, Eppenberger-Castori S, Güth U
Radiat Oncol 2014 May 30;9:126. doi: 10.1186/1748-717X-9-126. PMID: 24885766Free PMC Article

Clinical prediction guides

Unexpected finding.
Vallianou NG, Stavrinou N, Panagopoulos F, Geladari E, Sykaras AG, Vourlakou C
J Clin Pathol 2021 Apr;74(4):e6. Epub 2020 Oct 13 doi: 10.1136/jclinpath-2020-206770. PMID: 33051289
Randomized Trial Comparing Resection of Primary Tumor with No Surgery in Stage IV Breast Cancer at Presentation: Protocol MF07-01.
Soran A, Ozmen V, Ozbas S, Karanlik H, Muslumanoglu M, Igci A, Canturk Z, Utkan Z, Ozaslan C, Evrensel T, Uras C, Aksaz E, Soyder A, Ugurlu U, Col C, Cabioglu N, Bozkurt B, Uzunkoy A, Koksal N, Gulluoglu BM, Unal B, Atalay C, Yıldırım E, Erdem E, Salimoglu S, Sezer A, Koyuncu A, Gurleyik G, Alagol H, Ulufi N, Berberoglu U, Dulger M, Cengiz O, Sezgin E, Johnson R
Ann Surg Oncol 2018 Oct;25(11):3141-3149. Epub 2018 May 17 doi: 10.1245/s10434-018-6494-6. PMID: 29777404
What common biomarkers characterize a triple-negative profile in breast cancer?
Kallel I, Rebaï M, Khabir A, Rebaï A
Pathol Biol (Paris) 2015 Sep;63(4-5):224-9. Epub 2015 Aug 20 doi: 10.1016/j.patbio.2015.07.005. PMID: 26300241
Prolonged survival of patients with breast cancer-related leptomeningeal metastases.
Le Rhun E, Taillibert S, Zairi F, Pannier D, Boulanger T, Andre C, Cazin JL, Dubois F, Bonneterre J, Chamberlain MC
Anticancer Res 2013 May;33(5):2057-63. PMID: 23645756
Possible genetic predisposition to lymphedema after breast cancer.
Newman B, Lose F, Kedda MA, Francois M, Ferguson K, Janda M, Yates P, Spurdle AB, Hayes SC
Lymphat Res Biol 2012 Mar;10(1):2-13. Epub 2012 Mar 9 doi: 10.1089/lrb.2011.0024. PMID: 22404826Free PMC Article

Recent systematic reviews

Impact of Preoperative Magnetic Resonance Imaging on Surgical Outcomes in Women with Invasive Breast Cancer: A Systematic Review and Meta-Analysis.
Li L, Zhang Q, Qian C, Lin H
Int J Clin Pract 2022;2022:6440952. Epub 2022 Aug 25 doi: 10.1155/2022/6440952. PMID: 36081810Free PMC Article
The positive predictive value of vacuum assisted biopsy (VAB) in predicting final histological diagnosis for breast lesions of uncertain malignancy (B3 lesions): A systematic review & meta-analysis.
Cullinane C, Byrne J, Kelly L, O Sullivan M, Antony Corrigan M, Paul Redmond H
Eur J Surg Oncol 2022 Jul;48(7):1464-1474. Epub 2022 Apr 15 doi: 10.1016/j.ejso.2022.04.005. PMID: 35491362
Carcinomatous cirrhosis as radiographically occult liver metastases of breast cancer: A systematic literature review.
Hoshina H, Takei H, Nakamura M, Nishimoto F, Hanamura S
Cancer Treat Res Commun 2021;28:100388. Epub 2021 May 13 doi: 10.1016/j.ctarc.2021.100388. PMID: 34022480
Bladder Metastases from Breast Cancer: Managing the Unexpected. A Systematic Review.
Sanguedolce F, Landriscina M, Ambrosi A, Tartaglia N, Cianci P, Di Millo M, Carrieri G, Bufo P, Cormio L
Urol Int 2018;101(2):125-131. Epub 2017 Oct 20 doi: 10.1159/000481576. PMID: 29055945
High frequency of lobular breast cancer in distant metastases to the orbit.
Raap M, Antonopoulos W, Dämmrich M, Christgen H, Steinmann D, Länger F, Lehmann U, Kreipe H, Christgen M
Cancer Med 2015 Jan;4(1):104-11. Epub 2014 Oct 30 doi: 10.1002/cam4.331. PMID: 25355547Free PMC Article

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