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expressive language disorder

MedGen UID:
452300
•Concept ID:
C0236826
•
Mental or Behavioral Dysfunction
Synonyms: Developmental expressive language disorder; developmental expressive language disorder; Expressive Language Disorder
SNOMED CT: Developmental expressive language disorder (268734000)
 
Monarch Initiative: MONDO:0001276

Definition

A disorder characterized by an impairment in the development of an individual''s expressive language which is in contrast to his/her nonverbal intellect and receptive language development. The impairment may be acquired (i.e., due to a brain lesion or head trauma) or developmental (i.e., no known neurological insult). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVexpressive language disorder

Professional guidelines

PubMed

Co-morbidity and treatment of attention deficit hyperactivity disorder in Saudi Arabia.
Al-Haidar FA
East Mediterr Health J 2003 Sep-Nov;9(5-6):988-95. PMID: 16450529
Evaluation and management of the child with speech delay.
Leung AK, Kao CP
Am Fam Physician 1999 Jun;59(11):3121-8, 3135. PMID: 10392594

Recent clinical studies

Etiology

Prenatal, perinatal, postnatal risk factors, and excess screen time in autism spectrum disorder.
Güneş H, Tanıdır C, Doktur H, Yılmaz S, Yıldız D, Özbek F, Bozbey S, Özşirin G
Pediatr Int 2023 Jan;65(1):e15383. doi: 10.1111/ped.15383. PMID: 36210656
Comorbidity of fetal alcohol spectrum disorder: a systematic review and meta-analysis.
Popova S, Lange S, Shield K, Mihic A, Chudley AE, Mukherjee RAS, Bekmuradov D, Rehm J
Lancet 2016 Mar 5;387(10022):978-987. Epub 2016 Jan 6 doi: 10.1016/S0140-6736(15)01345-8. PMID: 26777270
Sensorimotor function in preschool-aged children with expressive language disorder.
Müürsepp I, Aibast H, Gapeyeva H, Pääsuke M
Res Dev Disabil 2014 Jun;35(6):1237-43. Epub 2014 Mar 28 doi: 10.1016/j.ridd.2014.03.007. PMID: 24685939
Ian: a 7-year old with prenatal drug exposure and early exposure to family violence.
Stein MT, Drahota A, Chavira DA
J Dev Behav Pediatr 2008 Dec;29(6):512-5. doi: 10.1097/DBP.0b013e3181903153. PMID: 19077846
Behavioral correlates of developmental expressive language disorder.
Caulfield MB, Fischel JE, DeBaryshe BD, Whitehurst GJ
J Abnorm Child Psychol 1989 Apr;17(2):187-201. doi: 10.1007/BF00913793. PMID: 2745899

Diagnosis

Prenatal, perinatal, postnatal risk factors, and excess screen time in autism spectrum disorder.
Güneş H, Tanıdır C, Doktur H, Yılmaz S, Yıldız D, Özbek F, Bozbey S, Özşirin G
Pediatr Int 2023 Jan;65(1):e15383. doi: 10.1111/ped.15383. PMID: 36210656
Comorbidity of fetal alcohol spectrum disorder: a systematic review and meta-analysis.
Popova S, Lange S, Shield K, Mihic A, Chudley AE, Mukherjee RAS, Bekmuradov D, Rehm J
Lancet 2016 Mar 5;387(10022):978-987. Epub 2016 Jan 6 doi: 10.1016/S0140-6736(15)01345-8. PMID: 26777270
Speech and language delay in children.
McLaughlin MR
Am Fam Physician 2011 May 15;83(10):1183-8. PMID: 21568252
Is expressive language disorder an accurate diagnostic category?
Leonard LB
Am J Speech Lang Pathol 2009 May;18(2):115-23. Epub 2008 Nov 24 doi: 10.1044/1058-0360(2008/08-0064). PMID: 19029534Free PMC Article
Evaluation and management of the child with speech delay.
Leung AK, Kao CP
Am Fam Physician 1999 Jun;59(11):3121-8, 3135. PMID: 10392594

Therapy

Adaptation, validity, and reliability of the Preschool Language Scale-Fifth Edition (PLS-5) in the Turkish context: The Turkish Preschool Language Scale-5 (TPLS-5).
Sahli AS, Belgin E
Int J Pediatr Otorhinolaryngol 2017 Jul;98:143-149. Epub 2017 May 10 doi: 10.1016/j.ijporl.2017.05.003. PMID: 28583491
Comorbidity of fetal alcohol spectrum disorder: a systematic review and meta-analysis.
Popova S, Lange S, Shield K, Mihic A, Chudley AE, Mukherjee RAS, Bekmuradov D, Rehm J
Lancet 2016 Mar 5;387(10022):978-987. Epub 2016 Jan 6 doi: 10.1016/S0140-6736(15)01345-8. PMID: 26777270
Clinical and biochemical outcome after hydroxocobalamin dose escalation in a series of patients with cobalamin C deficiency.
Matos IV, Castejón E, Meavilla S, O'Callaghan M, Garcia-Villoria J, López-Sala A, Ribes A, Artuch R, Garcia-Cazorla A
Mol Genet Metab 2013 Aug;109(4):360-5. Epub 2013 May 22 doi: 10.1016/j.ymgme.2013.05.007. PMID: 23746552
Ian: a 7-year old with prenatal drug exposure and early exposure to family violence.
Stein MT, Drahota A, Chavira DA
J Dev Behav Pediatr 2008 Dec;29(6):512-5. doi: 10.1097/DBP.0b013e3181903153. PMID: 19077846
Gabapentin and methylphenidate treatment of a preadolescent with attention deficit hyperactivity disorder and bipolar disorder.
Hamrin V, Bailey K
J Child Adolesc Psychopharmacol 2001 Fall;11(3):301-9. doi: 10.1089/10445460152595630. PMID: 11642481

Prognosis

X-linked myotubular myopathy: a clinical report and a review of the mild phenotype.
Barreto-Mota R, Figueirinha J, Quental R, Fonseca J, Melo C, Sampaio M, Sousa R
Rev Neurol 2023 Apr 1;76(7):243-246. doi: 10.33588/rn.7607.2021447. PMID: 36973888Free PMC Article
Speech and language delay in children.
McLaughlin MR
Am Fam Physician 2011 May 15;83(10):1183-8. PMID: 21568252
Role of assessment tests in the stability of intelligence scoring of pre-school children with uneven/delayed cognitive profile.
Yang P, Jong YJ, Hsu HY, Lung FW
J Intellect Disabil Res 2011 May;55(5):453-61. Epub 2011 Mar 6 doi: 10.1111/j.1365-2788.2011.01396.x. PMID: 21375639
Ian: a 7-year old with prenatal drug exposure and early exposure to family violence.
Stein MT, Drahota A, Chavira DA
J Dev Behav Pediatr 2008 Dec;29(6):512-5. doi: 10.1097/DBP.0b013e3181903153. PMID: 19077846
Language growth in children with expressive language delay.
Fischel JE, Whitehurst GJ, Caulfield MB, DeBaryshe B
Pediatrics 1989 Feb;83(2):218-27. PMID: 2913552

Clinical prediction guides

X-linked myotubular myopathy: a clinical report and a review of the mild phenotype.
Barreto-Mota R, Figueirinha J, Quental R, Fonseca J, Melo C, Sampaio M, Sousa R
Rev Neurol 2023 Apr 1;76(7):243-246. doi: 10.33588/rn.7607.2021447. PMID: 36973888Free PMC Article
Sensorimotor function in preschool-aged children with expressive language disorder.
Müürsepp I, Aibast H, Gapeyeva H, Pääsuke M
Res Dev Disabil 2014 Jun;35(6):1237-43. Epub 2014 Mar 28 doi: 10.1016/j.ridd.2014.03.007. PMID: 24685939
Role of assessment tests in the stability of intelligence scoring of pre-school children with uneven/delayed cognitive profile.
Yang P, Jong YJ, Hsu HY, Lung FW
J Intellect Disabil Res 2011 May;55(5):453-61. Epub 2011 Mar 6 doi: 10.1111/j.1365-2788.2011.01396.x. PMID: 21375639
Ian: a 7-year old with prenatal drug exposure and early exposure to family violence.
Stein MT, Drahota A, Chavira DA
J Dev Behav Pediatr 2008 Dec;29(6):512-5. doi: 10.1097/DBP.0b013e3181903153. PMID: 19077846
Behavioral correlates of developmental expressive language disorder.
Caulfield MB, Fischel JE, DeBaryshe BD, Whitehurst GJ
J Abnorm Child Psychol 1989 Apr;17(2):187-201. doi: 10.1007/BF00913793. PMID: 2745899

Recent systematic reviews

Comorbidity of fetal alcohol spectrum disorder: a systematic review and meta-analysis.
Popova S, Lange S, Shield K, Mihic A, Chudley AE, Mukherjee RAS, Bekmuradov D, Rehm J
Lancet 2016 Mar 5;387(10022):978-987. Epub 2016 Jan 6 doi: 10.1016/S0140-6736(15)01345-8. PMID: 26777270

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