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Extraventricular neurocytoma

MedGen UID:
457401
Concept ID:
C2985175
Neoplastic Process
Synonyms: EVN; Extraventricular Neurocytoma; extraventricular neurocytoma; Extraventricular Neurocytoma (WHO Grade 2); Extraventricular Neurocytoma (WHO Grade II); extraventricular neurocytoma (WHO grade II)
SNOMED CT: Extraventricular neurocytoma (716179006); Extraventricular neurocytoma (716787002)
 
Monarch Initiative: MONDO:0016727
Orphanet: ORPHA251927

Definition

A variant of central neurocytoma, a rare neuronal neoplasm, composed of round cells with neuronal differentiation, which is located outside of the ventricular system, usually within the spinal cord or cerebral hemispheres and that manifests with headache, nausea, vomiting, complex partial seizures or focal neurological deficits. In some cases it may exhibit atypical features consistent with aggressive clinical behaviour. [from SNOMEDCT_US]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVExtraventricular neurocytoma

Professional guidelines

PubMed

Mallick S, Roy S, Das S, Joshi NP, Roshan V, Gandhi AK, Jana M, Julka PK, Rath GK
Indian J Cancer 2015 Oct-Dec;52(4):590-7. doi: 10.4103/0019-509X.178378. PMID: 26960488
Patel DM, Schmidt RF, Liu JK
J Clin Neurosci 2013 Sep;20(9):1193-9. Epub 2013 Jun 27 doi: 10.1016/j.jocn.2013.01.001. PMID: 23810386

Recent clinical studies

Etiology

Huang S, Liu X, Zhu J, Sun Z, Chen Y, Yu H
J Coll Physicians Surg Pak 2022 Nov;32(11):1478-1482. doi: 10.29271/jcpsp.2022.11.1478. PMID: 36377019
Zhao X, Li M, Zhang G, Ren X, Yu S, Jiang H, Cui Y, Lin S
J Clin Neurosci 2022 May;99:379-386. Epub 2022 Mar 30 doi: 10.1016/j.jocn.2022.03.038. PMID: 35364441
Mallick S, Benson R, Rath GK
Neurol India 2018 Mar-Apr;66(2):362-367. doi: 10.4103/0028-3886.227262. PMID: 29547155
Zacharoulis S, Morales La Madrid A, Bandopadhayay P, Chi SN, Manley P, Ullrich NN, Marcus K, Goumnerova L, Scott RM, Proctor M, Young-Poussaint T, De Girolami U, Kieran MW
J Pediatr Hematol Oncol 2016 Aug;38(6):479-85. doi: 10.1097/MPH.0000000000000627. PMID: 27438020
Patil AS, Menon G, Easwer HV, Nair S
Acta Neurochir (Wien) 2014 Feb;156(2):349-54. Epub 2013 Dec 20 doi: 10.1007/s00701-013-1971-y. PMID: 24357019

Diagnosis

Mallick S, Benson R, Rath GK
Neurol India 2018 Mar-Apr;66(2):362-367. doi: 10.4103/0028-3886.227262. PMID: 29547155
Chen F, Jin R, Wu X, Dong Z, Chen D
World Neurosurg 2018 Apr;112:178-181. Epub 2018 Feb 22 doi: 10.1016/j.wneu.2018.01.104. PMID: 29378347
Zacharoulis S, Morales La Madrid A, Bandopadhayay P, Chi SN, Manley P, Ullrich NN, Marcus K, Goumnerova L, Scott RM, Proctor M, Young-Poussaint T, De Girolami U, Kieran MW
J Pediatr Hematol Oncol 2016 Aug;38(6):479-85. doi: 10.1097/MPH.0000000000000627. PMID: 27438020
Yang I, Ung N, Chung LK, Nagasawa DT, Thill K, Park J, Tenn S
Neurosurg Clin N Am 2015 Jan;26(1):5-10. doi: 10.1016/j.nec.2014.09.011. PMID: 25432178
Karki B, Tamrakar K, Kai XY, Kui WY, Wei ZW
JNMA J Nepal Med Assoc 2012 Oct-Dec;52(188):181-7. PMID: 23591250

Therapy

Chen MF, Yang SR, Tao JJ, Desilets A, Diamond EL, Wilhelm C, Rosen E, Gong Y, Mullaney K, Torrisi J, Young RJ, Somwar R, Yu HA, Kris MG, Riely GJ, Arcila ME, Ladanyi M, Donoghue MTA, Rosen N, Yaeger R, Drilon A, Murciano-Goroff YR, Offin M
Clin Cancer Res 2024 Sep 3;30(17):3812-3823. doi: 10.1158/1078-0432.CCR-23-3981. PMID: 38922339Free PMC Article
Makis W, McCann K, McEwan AJ
Clin Nucl Med 2015 Mar;40(3):234-6. doi: 10.1097/RLU.0000000000000668. PMID: 25608145

Prognosis

Mallick S, Benson R, Rath GK
Neurol India 2018 Mar-Apr;66(2):362-367. doi: 10.4103/0028-3886.227262. PMID: 29547155
Zacharoulis S, Morales La Madrid A, Bandopadhayay P, Chi SN, Manley P, Ullrich NN, Marcus K, Goumnerova L, Scott RM, Proctor M, Young-Poussaint T, De Girolami U, Kieran MW
J Pediatr Hematol Oncol 2016 Aug;38(6):479-85. doi: 10.1097/MPH.0000000000000627. PMID: 27438020
Kim JE, Lim M
Neurosurg Clin N Am 2015 Jan;26(1):109-15. doi: 10.1016/j.nec.2014.09.005. PMID: 25432190
Yang I, Ung N, Chung LK, Nagasawa DT, Thill K, Park J, Tenn S
Neurosurg Clin N Am 2015 Jan;26(1):5-10. doi: 10.1016/j.nec.2014.09.011. PMID: 25432178
Patil AS, Menon G, Easwer HV, Nair S
Acta Neurochir (Wien) 2014 Feb;156(2):349-54. Epub 2013 Dec 20 doi: 10.1007/s00701-013-1971-y. PMID: 24357019

Clinical prediction guides

Zhang P, Wu CY, Qin JZ, Xu RX, Bai MC, Wang LP, Dai YW, Li XZ
Cell Mol Biol (Noisy-le-grand) 2020 May 15;66(2):153-156. PMID: 32415952
Jiang M, Long L, Zeng J, Meng W, Zee C
J Neurooncol 2018 Nov;140(2):289-296. Epub 2018 Jul 30 doi: 10.1007/s11060-018-2952-z. PMID: 30062611
Huang WY, Zhang BY, Geng DY, Zhang J
Clin Radiol 2013 Apr;68(4):e206-12. Epub 2013 Jan 17 doi: 10.1016/j.crad.2012.11.009. PMID: 23332437
Sakurada K, Akasaka M, Kuchiki H, Saino M, Mori W, Sato S, Nakazato Y, Kayama T
Brain Tumor Pathol 2007;24(1):19-23. Epub 2007 May 25 doi: 10.1007/s10014-006-0210-0. PMID: 18095140
Moriguchi S, Yamashita A, Marutsuka K, Yoneyama T, Nakano S, Wakisaka S, Nabeshima K, Asada Y
Pathol Int 2006 Jan;56(1):25-9. doi: 10.1111/j.1440-1827.2006.01914.x. PMID: 16398676

Recent systematic reviews

Kweh BTS, Asaid M, Khoo B, Donaldson C, Lokan J, Gan HK, Gonzalvo AC
J Neurosurg 2024 May 1;140(5):1243-1253. Epub 2023 Nov 24 doi: 10.3171/2023.8.JNS231640. PMID: 38000064
Romano N, Federici M, Castaldi A
Radiol Med 2020 Oct;125(10):961-970. Epub 2020 Apr 25 doi: 10.1007/s11547-020-01198-8. PMID: 32335813

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