U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Hyaline degeneration

MedGen UID:
473044
•Concept ID:
C0333438
•
Pathologic Function
Synonym: Hyalinization
SNOMED CT: Hyaline degeneration (19010006); Hyaline thickening (19010006); Hyalinization (19010006); Hyalinosis (19010006)

Definition

A process of tissue replacement where the tissue is being replaced by hyaline or the tissue has degenerated to hyaline. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHyaline degeneration

Professional guidelines

PubMed

Clinical value of contrast-enhanced ultrasound for the differential diagnosis of specific subtypes of uterine leiomyomas.
Li Z, Zhang P, Shen H, Ding B, Wang H, Li J, Shen Y
J Obstet Gynaecol Res 2021 Jan;47(1):311-319. Epub 2020 Oct 18 doi: 10.1111/jog.14527. PMID: 33073436
Uterine leiomyomas: histopathologic features, MR imaging findings, differential diagnosis, and treatment.
Murase E, Siegelman ES, Outwater EK, Perez-Jaffe LA, Tureck RW
Radiographics 1999 Sep-Oct;19(5):1179-97. doi: 10.1148/radiographics.19.5.g99se131179. PMID: 10489175
Diffuse, perinodular, and other patterns of hydropic degeneration within and adjacent to uterine leiomyomas. Problems in differential diagnosis.
Clement PB, Young RH, Scully RE
Am J Surg Pathol 1992 Jan;16(1):26-32. doi: 10.1097/00000478-199201000-00004. PMID: 1309411

Recent clinical studies

Etiology

Mixed epithelial and stromal tumor of the kidney: A retrospective clinicopathological evaluation.
Feng R, Zhang T, Ke C, Tao Y, Wang Y
Ann Diagn Pathol 2023 Apr;63:152088. Epub 2022 Dec 23 doi: 10.1016/j.anndiagpath.2022.152088. PMID: 36577187
Pathological features of Brucella spondylitis: A single-center study.
Ma H, Zhang N, Liu J, Wang X, Yang Z, Lou C, Ji J, Zhai X, Niu N
Ann Diagn Pathol 2022 Jun;58:151910. Epub 2022 Feb 2 doi: 10.1016/j.anndiagpath.2022.151910. PMID: 35134730
The radiologic (CT/MRI)-pathological correlations of the salivary duct carcinoma (SDC) with hyaline degeneration and peripheral nerve invasion.
Kazawa N, Shibamoto Y, Hirose Y, Yamashita Y
Dentomaxillofac Radiol 2021 Oct 1;50(7):20200603. Epub 2021 Apr 20 doi: 10.1259/dmfr.20200603. PMID: 33877880Free PMC Article
Leksell Stereotactic Radiosurgery for Cavernous Malformations.
Lunsford LD, Niranjan A, Kano H, Monaco Iii EA, Flickinger JC
Prog Neurol Surg 2019;34:260-266. Epub 2019 May 16 doi: 10.1159/000493072. PMID: 31096254
IV. Uterine fibroid embolization: follow-up.
Lipman JC, Smith SJ, Spies JB, Siskin GP, Machan LS, Bonn J, Worthington-Kirsch RL, Goodwin SC, Hovsepian DM
Tech Vasc Interv Radiol 2002 Mar;5(1):44-55. doi: 10.1053/tvir.2002.124102. PMID: 12098107

Diagnosis

Chameleonic appearance of caseous calcification of the mitral valve - still a problem for its appropriate management.
Streian CG, Lascu A, Şoşdean R, Dima CN, Grosu F, Costache A, Motoc AGM
Rom J Morphol Embryol 2020 Apr-Jun;61(2):545-550. doi: 10.47162/RJME.61.2.25. PMID: 33544807Free PMC Article
Clinicopathological features of phlebosclerotic colitis.
Xu J, Jin M, Jiang Z, Ke Q, Li A, Zhu T, Lai M
Pathol Res Pract 2020 Nov;216(11):153193. Epub 2020 Aug 28 doi: 10.1016/j.prp.2020.153193. PMID: 32927306
Morphology and Evaluation of Renal Fibrosis.
Chen PS, Li YP, Ni HF
Adv Exp Med Biol 2019;1165:17-36. doi: 10.1007/978-981-13-8871-2_2. PMID: 31399959
Electron microscopic observations of glossal circumvallate papillae in dysgeusic patients.
Yasuda M, Tomita H
Acta Otolaryngol Suppl 2002;(546):122-8. doi: 10.1080/00016480260046508. PMID: 12132609
Hormonal pathology of the endometrium.
Deligdisch L
Mod Pathol 2000 Mar;13(3):285-94. doi: 10.1038/modpathol.3880050. PMID: 10757339

Therapy

Intrauterine Device Completely Encapsulated by Fibrous Tissue in a Postmenopausal Woman: A Case Report.
Huang Y, Zhang Y, Qu S, Chu Y
Br J Hosp Med (Lond) 2024 Sep 30;85(9):1-7. Epub 2024 Sep 19 doi: 10.12968/hmed.2024.0352. PMID: 39347657
A fatal chronic ketamine poisoning.
Tao Y, Chen XP, Qin ZH
J Forensic Sci 2005 Jan;50(1):173-6. PMID: 15831015
Electron microscopic observations of glossal circumvallate papillae in dysgeusic patients.
Yasuda M, Tomita H
Acta Otolaryngol Suppl 2002;(546):122-8. doi: 10.1080/00016480260046508. PMID: 12132609
Hormonal pathology of the endometrium.
Deligdisch L
Mod Pathol 2000 Mar;13(3):285-94. doi: 10.1038/modpathol.3880050. PMID: 10757339
Microscopic histopathology of chronic refractory lateral epicondylitis.
Regan W, Wold LE, Coonrad R, Morrey BF
Am J Sports Med 1992 Nov-Dec;20(6):746-9. doi: 10.1177/036354659202000618. PMID: 1280910

Prognosis

Implication of serum growth differentiation factor-15 level in patients with renal diseases.
Kobayashi S, Yamazaki H, Imamura T, Fujioka H, Kakeshita K, Koike T, Kinugawa K
Int Urol Nephrol 2023 Nov;55(11):2935-2941. Epub 2023 Apr 3 doi: 10.1007/s11255-023-03580-7. PMID: 37010737Free PMC Article
Clinicopathological features of low-grade malignant endolymphatic sac tumors.
Wang HQ, Jie L, Shi HY
Pathol Res Pract 2018 Mar;214(3):431-435. Epub 2017 Dec 14 doi: 10.1016/j.prp.2017.12.007. PMID: 29482989
Evaluation of uterine myomas during pregnancy using magnetic resonance imaging.
Tomasik P, Bomba-Opon D, Krupniewski L, Palczewski P, Wielgos M
Neuro Endocrinol Lett 2014;35(4):262-4. PMID: 25038597
Lipofibroadenoma of the thymus: a case report.
Qu G, Yu G, Zhang Q, Ma J, Wang X
Diagn Pathol 2013 Jul 15;8:117. doi: 10.1186/1746-1596-8-117. PMID: 23856156Free PMC Article
IV. Uterine fibroid embolization: follow-up.
Lipman JC, Smith SJ, Spies JB, Siskin GP, Machan LS, Bonn J, Worthington-Kirsch RL, Goodwin SC, Hovsepian DM
Tech Vasc Interv Radiol 2002 Mar;5(1):44-55. doi: 10.1053/tvir.2002.124102. PMID: 12098107

Clinical prediction guides

Implication of serum growth differentiation factor-15 level in patients with renal diseases.
Kobayashi S, Yamazaki H, Imamura T, Fujioka H, Kakeshita K, Koike T, Kinugawa K
Int Urol Nephrol 2023 Nov;55(11):2935-2941. Epub 2023 Apr 3 doi: 10.1007/s11255-023-03580-7. PMID: 37010737Free PMC Article
The radiologic (CT/MRI)-pathological correlations of the salivary duct carcinoma (SDC) with hyaline degeneration and peripheral nerve invasion.
Kazawa N, Shibamoto Y, Hirose Y, Yamashita Y
Dentomaxillofac Radiol 2021 Oct 1;50(7):20200603. Epub 2021 Apr 20 doi: 10.1259/dmfr.20200603. PMID: 33877880Free PMC Article
Electron microscopic observations of glossal circumvallate papillae in dysgeusic patients.
Yasuda M, Tomita H
Acta Otolaryngol Suppl 2002;(546):122-8. doi: 10.1080/00016480260046508. PMID: 12132609
Immunohistochemical study of myoglobin in neuromuscular diseases.
Kagawa N, Hizawa K
Muscle Nerve 1985 Jan;8(1):9-16. doi: 10.1002/mus.880080103. PMID: 3903489
"Hyaline degeneration" in severely atrophic muscle. Histochemical and electron microscopic observations.
Zacks SI, Lipshutz H, Markind S, Elliott FA
Brain 1968 Sep;91(3):463-72. doi: 10.1093/brain/91.3.463. PMID: 4177587

Recent systematic reviews

Primary pulmonary hyalinizing clear cell carcinoma with vocal-cord squamous cell carcinoma: a case report with systematic review.
Li Z, Li W, Xue L
Diagn Pathol 2023 Aug 8;18(1):90. doi: 10.1186/s13000-023-01376-y. PMID: 37553667Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...