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Juvenile Polyp of the Small Intestine

MedGen UID:
474152
•Concept ID:
C3272519
•
Disease or Syndrome
Synonym: Small Intestinal Retention Polyp

Definition

A non-neoplastic hamartomatous polyp that arises from the small intestine. It is characterized by the presence of tortuous and cystically dilated glands, edematous changes, and inflammation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVJuvenile Polyp of the Small Intestine

Professional guidelines

PubMed

Updates in the diagnosis and management of non-ampullary small-bowel polyposis.
Lucaciu L, Yano T, Saurin JC
Best Pract Res Clin Gastroenterol 2023 Jun-Aug;64-65:101852. Epub 2023 Jul 22 doi: 10.1016/j.bpg.2023.101852. PMID: 37652652
Management of small bowel polyps: A literature review.
de Latour RA, Kilaru SM, Gross SA
Best Pract Res Clin Gastroenterol 2017 Aug;31(4):401-408. Epub 2017 Jun 27 doi: 10.1016/j.bpg.2017.06.003. PMID: 28842049

Recent clinical studies

Etiology

Characterization of Colonoscopies in Preschool Children.
Bolia R, Thapar N, Withers GD, Ee LC
J Pediatr Gastroenterol Nutr 2023 Sep 1;77(3):396-400. Epub 2023 May 12 doi: 10.1097/MPG.0000000000003826. PMID: 37184503
Rare Isolated Duodenal Hamartomatous Polyp in an Elderly Patient.
Mahmoud A, Soliman IM, Kania BE, Ghrewati M, Baddoura W
Am J Case Rep 2023 Feb 17;24:e938929. doi: 10.12659/AJCR.938929. PMID: 36798003Free PMC Article
Malignant tumors associated with juvenile polyposis syndrome in Japan.
Ishida H, Ishibashi K, Iwama T
Surg Today 2018 Mar;48(3):253-263. Epub 2017 May 26 doi: 10.1007/s00595-017-1538-2. PMID: 28550623
Colorectal polyps in childhood.
Thakkar K, Fishman DS, Gilger MA
Curr Opin Pediatr 2012 Oct;24(5):632-7. doi: 10.1097/MOP.0b013e328357419f. PMID: 22890064
Epithelial and neuroendocrine tumors of the duodenum.
Attanoos R, Williams GT
Semin Diagn Pathol 1991 Aug;8(3):149-62. PMID: 1925122

Diagnosis

Updates in the diagnosis and management of non-ampullary small-bowel polyposis.
Lucaciu L, Yano T, Saurin JC
Best Pract Res Clin Gastroenterol 2023 Jun-Aug;64-65:101852. Epub 2023 Jul 22 doi: 10.1016/j.bpg.2023.101852. PMID: 37652652
Characterization of Colonoscopies in Preschool Children.
Bolia R, Thapar N, Withers GD, Ee LC
J Pediatr Gastroenterol Nutr 2023 Sep 1;77(3):396-400. Epub 2023 May 12 doi: 10.1097/MPG.0000000000003826. PMID: 37184503
Malignant tumors associated with juvenile polyposis syndrome in Japan.
Ishida H, Ishibashi K, Iwama T
Surg Today 2018 Mar;48(3):253-263. Epub 2017 May 26 doi: 10.1007/s00595-017-1538-2. PMID: 28550623
Management of small bowel polyps: A literature review.
de Latour RA, Kilaru SM, Gross SA
Best Pract Res Clin Gastroenterol 2017 Aug;31(4):401-408. Epub 2017 Jun 27 doi: 10.1016/j.bpg.2017.06.003. PMID: 28842049
Colorectal polyps in childhood.
Thakkar K, Fishman DS, Gilger MA
Curr Opin Pediatr 2012 Oct;24(5):632-7. doi: 10.1097/MOP.0b013e328357419f. PMID: 22890064

Therapy

Characterization of Colonoscopies in Preschool Children.
Bolia R, Thapar N, Withers GD, Ee LC
J Pediatr Gastroenterol Nutr 2023 Sep 1;77(3):396-400. Epub 2023 May 12 doi: 10.1097/MPG.0000000000003826. PMID: 37184503
Colorectal polyps in childhood.
Thakkar K, Fishman DS, Gilger MA
Curr Opin Pediatr 2012 Oct;24(5):632-7. doi: 10.1097/MOP.0b013e328357419f. PMID: 22890064
Neoplasia in ileal pouch mucosa after total proctocolectomy for juvenile polyposis: report of a case.
Stoltenberg RL, Madsen JA, Schlack SC, Harms BA, Jacoby RF
Dis Colon Rectum 1997 Jun;40(6):726-30. doi: 10.1007/BF02140904. PMID: 9194469
Colonic polyps complicating ureterosigmoidostomy.
Ansell ID, Vellacott KD
Histopathology 1980 Jul;4(4):429-36. doi: 10.1111/j.1365-2559.1980.tb02937.x. PMID: 7429431

Prognosis

Rare Isolated Duodenal Hamartomatous Polyp in an Elderly Patient.
Mahmoud A, Soliman IM, Kania BE, Ghrewati M, Baddoura W
Am J Case Rep 2023 Feb 17;24:e938929. doi: 10.12659/AJCR.938929. PMID: 36798003Free PMC Article
A rare case of a juvenile polyp of patient with Peutz-Jeghers syndrome, complicated with intussusception of the small intestine.
Rycyk A, Kasztelan-Szczerbinska B, Cichoz-Lach H
Folia Med (Plovdiv) 2022 Aug 31;64(4):693-696. doi: 10.3897/folmed.64.e67044. PMID: 36045464
Diagnostic Accuracy of Meckel Scan with Initial Hemoglobin Level to Detect Symptomatic Meckel Diverticulum.
Suh M, Lee HY, Jung K, Kim SE
Eur J Pediatr Surg 2015 Oct;25(5):449-53. Epub 2014 Nov 25 doi: 10.1055/s-0034-1387949. PMID: 25422901
Peutz-Jeghers syndrome: a critical look at colonic Peutz-Jeghers polyps.
Tse JY, Wu S, Shinagare SA, Lauwers GY, Yilmaz O, Wu CL, Deshpande V
Mod Pathol 2013 Sep;26(9):1235-40. Epub 2013 Apr 19 doi: 10.1038/modpathol.2013.44. PMID: 23599156
Giant stomach secondary to juvenile polyposis syndrome.
Wong-Chong N, Kidanewold WH, Kirsch R, May GR, McCart JA
J Gastrointest Surg 2012 Mar;16(3):669-72. Epub 2011 Oct 18 doi: 10.1007/s11605-011-1714-4. PMID: 22005895

Clinical prediction guides

A rare case of a juvenile polyp of patient with Peutz-Jeghers syndrome, complicated with intussusception of the small intestine.
Rycyk A, Kasztelan-Szczerbinska B, Cichoz-Lach H
Folia Med (Plovdiv) 2022 Aug 31;64(4):693-696. doi: 10.3897/folmed.64.e67044. PMID: 36045464
Diagnostic Accuracy of Meckel Scan with Initial Hemoglobin Level to Detect Symptomatic Meckel Diverticulum.
Suh M, Lee HY, Jung K, Kim SE
Eur J Pediatr Surg 2015 Oct;25(5):449-53. Epub 2014 Nov 25 doi: 10.1055/s-0034-1387949. PMID: 25422901
Peutz-Jeghers syndrome: a critical look at colonic Peutz-Jeghers polyps.
Tse JY, Wu S, Shinagare SA, Lauwers GY, Yilmaz O, Wu CL, Deshpande V
Mod Pathol 2013 Sep;26(9):1235-40. Epub 2013 Apr 19 doi: 10.1038/modpathol.2013.44. PMID: 23599156
Ectopic expression of the Y (Ley) antigen defined by monoclonal antibody 12-4LE in distal colonic adenocarcinomas.
Bara J, Mollicone R, Herrero-Zabaleta E, Gautier R, Daher N, Oriol R
Int J Cancer 1988 May 15;41(5):683-9. doi: 10.1002/ijc.2910410508. PMID: 3284823

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