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Enanthema

MedGen UID:
507677
•Concept ID:
C0014034
•
Sign or Symptom
Synonyms: Enanthem; Enanthemata; Mucous membrane eruption
SNOMED CT: Mucous membrane eruption (5862001); Enanthem (5862001); Enanthemata (5862001); Enanthema (5862001)
 
HPO: HP:0030249

Definition

A sudden eruption (rash) of the surface of a mucous membrane of the mouth or pharynx. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEnanthema

Professional guidelines

PubMed

[Translated article] AEDV Expert Consensus for the Management of Syphilis.
Fuertes de Vega L, de la Torre García JM, Suarez Farfante JM, Ceballos Rodríguez MC
Actas Dermosifiliogr 2024 Oct;115(9):T896-T905. Epub 2024 Aug 5 doi: 10.1016/j.ad.2024.08.006. PMID: 39111574
AEDV Expert Consensus for the Management of Syphilis.
Fuertes de Vega L, de la Torre García JM, Suarez Farfante JM, Ceballos Rodríguez MC
Actas Dermosifiliogr 2024 Oct;115(9):896-905. Epub 2024 Apr 23 doi: 10.1016/j.ad.2024.03.033. PMID: 38663730
Flumethasone pivalate (Locorten) in the treatment of oral diseases.
Scaglione F, Falchi M, Bichisao E, Fraschini F
Drugs Exp Clin Res 1985;11(8):523-6. PMID: 3915470

Recent clinical studies

Etiology

Cutaneous manifestations in hospitalized patients diagnosed as COVID-19.
Askin O, Altunkalem RN, Altinisik DD, Uzuncakmak TK, Tursen U, Kutlubay Z
Dermatol Ther 2020 Nov;33(6):e13896. Epub 2020 Jul 31 doi: 10.1111/dth.13896. PMID: 32579756Free PMC Article
Oropharyngeal lesions in pityriasis rosea.
Ciccarese G, Broccolo F, Rebora A, Parodi A, Drago F
J Am Acad Dermatol 2017 Nov;77(5):833-837.e4. Epub 2017 Jul 18 doi: 10.1016/j.jaad.2017.06.033. PMID: 28728872
Efficacy of additional i.v. immunoglobulin to steroid therapy in Stevens-Johnson syndrome and toxic epidermal necrolysis.
Aihara M, Kano Y, Fujita H, Kambara T, Matsukura S, Katayama I, Azukizawa H, Miyachi Y, Endo Y, Asada H, Miyagawa F, Morita E, Kaneko S, Abe R, Ochiai T, Sueki H, Watanabe H, Nagao K, Aoyama Y, Sayama K, Hashimoto K, Shiohara T; SJS/TEN Study Group
J Dermatol 2015 Aug;42(8):768-77. Epub 2015 May 18 doi: 10.1111/1346-8138.12925. PMID: 25982480
Terminal ileum of patients who underwent colonoscopy: endoscopic, histologic and clinical aspects.
Melo MM, Cury PM, Ronchi LS, Gonçalves-Filho Fde A, Cunrath GS, Netinho JG
Arq Gastroenterol 2009 Apr-Jun;46(2):102-6. doi: 10.1590/s0004-28032009000200005. PMID: 19578609
Atypical exanthems: morphology and laboratory investigations may lead to an aetiological diagnosis in about 70% of cases.
Drago F, Rampini E, Rebora A
Br J Dermatol 2002 Aug;147(2):255-60. doi: 10.1046/j.1365-2133.2002.04826.x. PMID: 12174095

Diagnosis

Herpetic gingivostomatitis in a young adult.
Katayama S
Pan Afr Med J 2022;41:113. Epub 2022 Feb 8 doi: 10.11604/pamj.2022.41.113.32711. PMID: 35465363Free PMC Article
Palatopharyngeal vesicular enanthem, early finding of COVID-19.
Domínguez-Rodas J, Ramírez-García SA, Dávalos-Rodríguez NO, Cabrera-Pivaral CE
Cir Cir 2021;89(5):692-693. doi: 10.24875/CIRU.21000279. PMID: 34665169
Cutaneous manifestations in hospitalized patients diagnosed as COVID-19.
Askin O, Altunkalem RN, Altinisik DD, Uzuncakmak TK, Tursen U, Kutlubay Z
Dermatol Ther 2020 Nov;33(6):e13896. Epub 2020 Jul 31 doi: 10.1111/dth.13896. PMID: 32579756Free PMC Article
Whipple's disease: rare disorder and late diagnosis.
Renon VP, Appel-da-Silva MC, D'Incao RB, Lul RM, Kirschnick LS, Galperim B
Rev Inst Med Trop Sao Paulo 2012 Sep-Oct;54(5):293-7. doi: 10.1590/s0036-46652012000500010. PMID: 22983294
Geotrichosis of oral mucosa.
Listemann H, Schönrock-Nabulsi P, Kuse R, Meigel W
Mycoses 1996 Jul-Aug;39(7-8):289-91. doi: 10.1111/j.1439-0507.1996.tb00140.x. PMID: 9009647

Therapy

AEDV Expert Consensus for the Management of Syphilis.
Fuertes de Vega L, de la Torre García JM, Suarez Farfante JM, Ceballos Rodríguez MC
Actas Dermosifiliogr 2024 Oct;115(9):896-905. Epub 2024 Apr 23 doi: 10.1016/j.ad.2024.03.033. PMID: 38663730
Whipple's disease: rare disorder and late diagnosis.
Renon VP, Appel-da-Silva MC, D'Incao RB, Lul RM, Kirschnick LS, Galperim B
Rev Inst Med Trop Sao Paulo 2012 Sep-Oct;54(5):293-7. doi: 10.1590/s0036-46652012000500010. PMID: 22983294
Geotrichosis of oral mucosa.
Listemann H, Schönrock-Nabulsi P, Kuse R, Meigel W
Mycoses 1996 Jul-Aug;39(7-8):289-91. doi: 10.1111/j.1439-0507.1996.tb00140.x. PMID: 9009647
Fluconazole in the treatment of oropharyngeal candidosis in HIV-positive patients.
Just-Nübling G, Gentschew G, Döhle M, Böttinger C, Helm EB, Stille W
Mycoses 1990 Sep-Oct;33(9-10):435-40. doi: 10.1111/myc.1990.33.9-10.435. PMID: 2093839
Flumethasone pivalate (Locorten) in the treatment of oral diseases.
Scaglione F, Falchi M, Bichisao E, Fraschini F
Drugs Exp Clin Res 1985;11(8):523-6. PMID: 3915470

Prognosis

Cutaneous manifestations in hospitalized patients diagnosed as COVID-19.
Askin O, Altunkalem RN, Altinisik DD, Uzuncakmak TK, Tursen U, Kutlubay Z
Dermatol Ther 2020 Nov;33(6):e13896. Epub 2020 Jul 31 doi: 10.1111/dth.13896. PMID: 32579756Free PMC Article
Oropharyngeal lesions in pityriasis rosea.
Ciccarese G, Broccolo F, Rebora A, Parodi A, Drago F
J Am Acad Dermatol 2017 Nov;77(5):833-837.e4. Epub 2017 Jul 18 doi: 10.1016/j.jaad.2017.06.033. PMID: 28728872
African tick bite fever in elderly patients: 8 cases in French tourists returning from South Africa.
Roch N, Epaulard O, Pelloux I, Pavese P, Brion JP, Raoult D, Maurin M
Clin Infect Dis 2008 Aug 1;47(3):e28-35. doi: 10.1086/589868. PMID: 18558881
Fluconazole in the treatment of oropharyngeal candidosis in HIV-positive patients.
Just-Nübling G, Gentschew G, Döhle M, Böttinger C, Helm EB, Stille W
Mycoses 1990 Sep-Oct;33(9-10):435-40. doi: 10.1111/myc.1990.33.9-10.435. PMID: 2093839

Clinical prediction guides

Cutaneous manifestations in hospitalized patients diagnosed as COVID-19.
Askin O, Altunkalem RN, Altinisik DD, Uzuncakmak TK, Tursen U, Kutlubay Z
Dermatol Ther 2020 Nov;33(6):e13896. Epub 2020 Jul 31 doi: 10.1111/dth.13896. PMID: 32579756Free PMC Article
Oropharyngeal lesions in pityriasis rosea.
Ciccarese G, Broccolo F, Rebora A, Parodi A, Drago F
J Am Acad Dermatol 2017 Nov;77(5):833-837.e4. Epub 2017 Jul 18 doi: 10.1016/j.jaad.2017.06.033. PMID: 28728872
Recurrent male herpes genitalis with two different strains of herpes simplex virus type 2.
Yoshida M, Tezuka T
J Dermatol 1990 Apr;17(4):252-4. doi: 10.1111/j.1346-8138.1990.tb01634.x. PMID: 2164052
Fluconazole in the treatment of oropharyngeal candidosis in HIV-positive patients.
Just-Nübling G, Gentschew G, Döhle M, Böttinger C, Helm EB, Stille W
Mycoses 1990 Sep-Oct;33(9-10):435-40. doi: 10.1111/myc.1990.33.9-10.435. PMID: 2093839
Application of microassay technique in cell-mediated immunity to measles virus infection.
Yamanaka T, Chiba S, Nakao T
Tohoku J Exp Med 1976 Nov;120(3):225-9. doi: 10.1620/tjem.120.225. PMID: 996848

Recent systematic reviews

Oral lesions in patients with human monkeypox: A systematic scoping review.
Ardila CM, Arrubla-Escobar DE, Vivares-Builes AM
J Oral Pathol Med 2023 Jul;52(6):459-467. Epub 2022 Nov 2 doi: 10.1111/jop.13375. PMID: 36263594
COVID-19-related oral mucosa lesions among confirmed SARS-CoV-2 patients: a systematic review.
Erbaş GS, Botsali A, Erden N, Arı C, Taşkın B, Alper S, Vural S
Int J Dermatol 2022 Jan;61(1):20-32. Epub 2021 Sep 22 doi: 10.1111/ijd.15889. PMID: 34549816Free PMC Article

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