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Hemorrhagic cystitis

MedGen UID:
508360
•Concept ID:
C0085692
•
Disease or Syndrome
Synonyms: Cystitis, Hemorrhagic; Hemorrhagic Cystitis
SNOMED CT: Hemorrhagic cystitis (87696004)
 
Monarch Initiative: MONDO:0000496

Definition

Inflammation of the bladder resulting in bloody urine. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHemorrhagic cystitis

Professional guidelines

PubMed

Hemorrhagic cystitis: a review of the literature and treatment options.
D'Amico MJ, Foss H, Uhr A, Rudnick B, Kloniecke E, Gomella LG
Can J Urol 2022 Oct;29(5):11276-11283. PMID: 36245196
Adenovirus: Epidemiology, Global Spread of Novel Serotypes, and Advances in Treatment and Prevention.
Lynch JP 3rd, Kajon AE
Semin Respir Crit Care Med 2016 Aug;37(4):586-602. Epub 2016 Aug 3 doi: 10.1055/s-0036-1584923. PMID: 27486739Free PMC Article
Hypebaric oxygen treatment in urology.
Gallego Vilar D, García Fadrique G, Povo Martín IJ, Miralles Aguado J, Garau Perelló C, Sanchis Verdú L, Gimeno Argente V, Bosquet Sanz M, Aliaga MR, Claramonte Ramón FJ, Gallego Gómez J
Arch Esp Urol 2011 Jul;64(6):507-16. PMID: 21791717

Recent clinical studies

Etiology

Acute kidney injury in cancer patients.
Liu S, Zhao J, Wang F
Clin Exp Nephrol 2022 Feb;26(2):103-112. Epub 2021 Sep 9 doi: 10.1007/s10157-021-02131-7. PMID: 34499266
BK polyomavirus-pathogen, paradigm and puzzle.
Kotla SK, Kadambi PV, Hendricks AR, Rojas R
Nephrol Dial Transplant 2021 Mar 29;36(4):587-593. doi: 10.1093/ndt/gfz273. PMID: 31891401
BK and Other Polyomaviruses in Kidney Transplantation.
Trofe-Clark J, Sawinski D
Semin Nephrol 2016 Sep;36(5):372-385. doi: 10.1016/j.semnephrol.2016.05.014. PMID: 27772622
Adenovirus: Epidemiology, Global Spread of Novel Serotypes, and Advances in Treatment and Prevention.
Lynch JP 3rd, Kajon AE
Semin Respir Crit Care Med 2016 Aug;37(4):586-602. Epub 2016 Aug 3 doi: 10.1055/s-0036-1584923. PMID: 27486739Free PMC Article
Adenovirus.
Lynch JP 3rd, Fishbein M, Echavarria M
Semin Respir Crit Care Med 2011 Aug;32(4):494-511. Epub 2011 Aug 19 doi: 10.1055/s-0031-1283287. PMID: 21858752

Diagnosis

Hemorrhagic cystitis: a review of the literature and treatment options.
D'Amico MJ, Foss H, Uhr A, Rudnick B, Kloniecke E, Gomella LG
Can J Urol 2022 Oct;29(5):11276-11283. PMID: 36245196
Adenovirus Infection and Transplantation.
Al-Heeti OM, Cathro HP, Ison MG
Transplantation 2022 May 1;106(5):920-927. Epub 2021 Nov 24 doi: 10.1097/TP.0000000000003988. PMID: 34856601Free PMC Article
Acute kidney injury in cancer patients.
Liu S, Zhao J, Wang F
Clin Exp Nephrol 2022 Feb;26(2):103-112. Epub 2021 Sep 9 doi: 10.1007/s10157-021-02131-7. PMID: 34499266
BK polyomavirus-pathogen, paradigm and puzzle.
Kotla SK, Kadambi PV, Hendricks AR, Rojas R
Nephrol Dial Transplant 2021 Mar 29;36(4):587-593. doi: 10.1093/ndt/gfz273. PMID: 31891401
BK and JC virus: a review.
Pinto M, Dobson S
J Infect 2014 Jan;68 Suppl 1:S2-8. Epub 2013 Oct 8 doi: 10.1016/j.jinf.2013.09.009. PMID: 24119828

Therapy

Posoleucel, an Allogeneic, Off-the-Shelf Multivirus-Specific T-Cell Therapy, for the Treatment of Refractory Viral Infections in the Post-HCT Setting.
Pfeiffer T, Tzannou I, Wu M, Ramos C, Sasa G, Martinez C, Lulla P, Krance RA, Scherer L, Ruderfer D, Naik S, Bocchini C, Fraser IP, Patel B, Ward D, Wang T, Heslop HE, Leen AM, Omer B
Clin Cancer Res 2023 Jan 17;29(2):324-330. doi: 10.1158/1078-0432.CCR-22-2415. PMID: 36628536Free PMC Article
Adenovirus: Epidemiology, Global Spread of Novel Types, and Approach to Treatment.
Lynch JP 3rd, Kajon AE
Semin Respir Crit Care Med 2021 Dec;42(6):800-821. Epub 2021 Dec 16 doi: 10.1055/s-0041-1733802. PMID: 34918322
Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoietic Stem-Cell Transplantation.
Tzannou I, Papadopoulou A, Naik S, Leung K, Martinez CA, Ramos CA, Carrum G, Sasa G, Lulla P, Watanabe A, Kuvalekar M, Gee AP, Wu MF, Liu H, Grilley BJ, Krance RA, Gottschalk S, Brenner MK, Rooney CM, Heslop HE, Leen AM, Omer B
J Clin Oncol 2017 Nov 1;35(31):3547-3557. Epub 2017 Aug 7 doi: 10.1200/JCO.2017.73.0655. PMID: 28783452Free PMC Article
Adenovirus.
Lynch JP 3rd, Fishbein M, Echavarria M
Semin Respir Crit Care Med 2011 Aug;32(4):494-511. Epub 2011 Aug 19 doi: 10.1055/s-0031-1283287. PMID: 21858752
Hypebaric oxygen treatment in urology.
Gallego Vilar D, García Fadrique G, Povo Martín IJ, Miralles Aguado J, Garau Perelló C, Sanchis Verdú L, Gimeno Argente V, Bosquet Sanz M, Aliaga MR, Claramonte Ramón FJ, Gallego Gómez J
Arch Esp Urol 2011 Jul;64(6):507-16. PMID: 21791717

Prognosis

Molecular Iodine/Cyclophosphamide Synergism on Chemoresistant Neuroblastoma Models.
Álvarez-León W, Mendieta I, Delgado-González E, Anguiano B, Aceves C
Int J Mol Sci 2021 Aug 19;22(16) doi: 10.3390/ijms22168936. PMID: 34445656Free PMC Article
Incidence and risk factor of hemorrhagic cystitis after allogeneic transplantation with fludarabine, busulfan, and anti-thymocyte globulin myeloablative conditioning.
Lam W, Storek J, Li H, Geddes M, Daly A
Transpl Infect Dis 2017 Jun;19(3) Epub 2017 Apr 17 doi: 10.1111/tid.12677. PMID: 28199755
Robot-assisted radical cystectomy in octogenarians.
Phillips EA, Uberoi V, Tuerk IA
J Endourol 2014 Feb;28(2):219-23. Epub 2013 Dec 26 doi: 10.1089/end.2013.0159. PMID: 24074288
Surgical management of complications of multimodal therapy.
Chui CH
Pediatr Blood Cancer 2012 Aug;59(2):405-9. Epub 2012 Mar 20 doi: 10.1002/pbc.24147. PMID: 22434785
Management of refractory hemorrhagic cystitis following hematopoietic stem cell transplantation in children.
Hassan Z
Pediatr Transplant 2011 Jun;15(4):348-61. Epub 2011 Apr 19 doi: 10.1111/j.1399-3046.2011.01505.x. PMID: 21504524

Clinical prediction guides

Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoietic Stem-Cell Transplantation.
Tzannou I, Papadopoulou A, Naik S, Leung K, Martinez CA, Ramos CA, Carrum G, Sasa G, Lulla P, Watanabe A, Kuvalekar M, Gee AP, Wu MF, Liu H, Grilley BJ, Krance RA, Gottschalk S, Brenner MK, Rooney CM, Heslop HE, Leen AM, Omer B
J Clin Oncol 2017 Nov 1;35(31):3547-3557. Epub 2017 Aug 7 doi: 10.1200/JCO.2017.73.0655. PMID: 28783452Free PMC Article
Robot-assisted radical cystectomy in octogenarians.
Phillips EA, Uberoi V, Tuerk IA
J Endourol 2014 Feb;28(2):219-23. Epub 2013 Dec 26 doi: 10.1089/end.2013.0159. PMID: 24074288
Human polyomaviruses in disease and cancer.
Dalianis T, Hirsch HH
Virology 2013 Mar 15;437(2):63-72. Epub 2013 Jan 26 doi: 10.1016/j.virol.2012.12.015. PMID: 23357733
Cyclophosphamide for treating rheumatoid arthritis.
Suarez-Almazor ME, Belseck E, Shea B, Wells G, Tugwell P
Cochrane Database Syst Rev 2000;(4):CD001157. doi: 10.1002/14651858.CD001157. PMID: 11034702
Cyclophosphamide for rheumatoid arthritis.
Suarez-Almazor ME, Belseck E, Shea B, Wells G, Tugwell P
Cochrane Database Syst Rev 2000;2000(2):CD001157. doi: 10.1002/14651858.CD001157. PMID: 10796419Free PMC Article

Recent systematic reviews

Risk factors for BK virus-associated hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation: A systematic review and meta-analysis.
Zhou X, Zhang S, Fan J, Zhu X, Hu S
Clin Transplant 2023 Nov;37(11):e15121. Epub 2023 Sep 7 doi: 10.1111/ctr.15121. PMID: 37676427
Incidence of hemorrhagic cystitis after cyclophosphamide therapy with or without mesna: A cohort study and comprehensive literature review.
Almalag HM, Alasmari SS, Alrayes MH, Binhameed MA, Alsudairi RA, Alosaimi MM, Alnasser GA, Abuzaid RA, Khalil N, Abouzaid HH, Alarfaj AS
J Oncol Pharm Pract 2021 Mar;27(2):340-349. Epub 2020 May 1 doi: 10.1177/1078155220920690. PMID: 32356687
Hypebaric oxygen treatment in urology.
Gallego Vilar D, García Fadrique G, Povo Martín IJ, Miralles Aguado J, Garau Perelló C, Sanchis Verdú L, Gimeno Argente V, Bosquet Sanz M, Aliaga MR, Claramonte Ramón FJ, Gallego Gómez J
Arch Esp Urol 2011 Jul;64(6):507-16. PMID: 21791717
Cyclophosphamide for treating rheumatoid arthritis.
Suarez-Almazor ME, Belseck E, Shea B, Wells G, Tugwell P
Cochrane Database Syst Rev 2000;(4):CD001157. doi: 10.1002/14651858.CD001157. PMID: 11034702
Cyclophosphamide for rheumatoid arthritis.
Suarez-Almazor ME, Belseck E, Shea B, Wells G, Tugwell P
Cochrane Database Syst Rev 2000;2000(2):CD001157. doi: 10.1002/14651858.CD001157. PMID: 10796419Free PMC Article

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