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Hepatic infarction

MedGen UID:
508812
•Concept ID:
C0151731
•
Disease or Syndrome
Synonyms: Hepatic Infarct; Hepatic Infarction; Hepatic Infarctions; Hepatic Infarcts; Infarct, Hepatic; Infarct, Liver; Infarction, Hepatic; Infarction, Liver; Liver Infarct; Liver Infarction; Liver Infarctions; Liver Infarcts
SNOMED CT: Infarction of liver (17890003); Hepatic infarction (17890003); Infarct of liver (17890003)
 
HPO: HP:0033135
Monarch Initiative: MONDO:0001787

Definition

Hepatic infarction is defined as areas of coagulative necrosis from hepatocyte cell death caused by local ischemia. Liver infarctions appear as hypoechoic nonvascular regions on conventional and Doppler sonography. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHepatic infarction

Professional guidelines

PubMed

Assessment of Clinical Outcomes, Clinical Manifestations, and Risk Factors for Hepatic Infarction After Transjugular Intrahepatic Portosystemic Shunt Placement (TIPS): A Retrospective Comparative Study.
Tuifua TS, Partovi S, Remer EM, Ragheb J, Bullen JA, Kattan MW, Kapoor B
Cardiovasc Intervent Radiol 2022 Oct;45(10):1512-1523. Epub 2022 Jul 18 doi: 10.1007/s00270-022-03219-7. PMID: 35851823
Complications of percutaneous radiofrequency ablation for hepato-cellular carcinoma: imaging spectrum and management.
Akahane M, Koga H, Kato N, Yamada H, Uozumi K, Tateishi R, Teratani T, Shiina S, Ohtomo K
Radiographics 2005 Oct;25 Suppl 1:S57-68. doi: 10.1148/rg.25si055505. PMID: 16227497
Styrene maleic acid neocarzinostatin treatment for hepatocellular carcinoma.
Abe S, Otsuki M
Curr Med Chem Anticancer Agents 2002 Nov;2(6):715-26. doi: 10.2174/1568011023353679. PMID: 12678722

Recent clinical studies

Etiology

Hepatic infarction in pregnancy: a systematic review.
Munter BT, Boyd AR, Tchani R, Gray JN, Ramsey PS
Am J Obstet Gynecol MFM 2024 Jun;6(6):101377. Epub 2024 Apr 14 doi: 10.1016/j.ajogmf.2024.101377. PMID: 38621440
Liver stiffness and steatosis in preeclampsia as shown by transient elastography-a prospective cohort study.
Carmiel Haggai M, Sgayer I, Bornstein J, Odeh M, Lowenstein L, Frank Wolf M
Am J Obstet Gynecol 2022 Sep;227(3):515.e1-515.e9. Epub 2022 Apr 29 doi: 10.1016/j.ajog.2022.04.048. PMID: 35500613
Venous thrombosis and segmental hypoperfusion in amebic liver abscess: MDCT demonstration and its implications.
Priyadarshi RN, Kumar P, Kumar R, Anand U, Shyama
Abdom Radiol (NY) 2020 Mar;45(3):652-660. doi: 10.1007/s00261-020-02409-6. PMID: 31955219
Complications of percutaneous radiofrequency ablation for hepato-cellular carcinoma: imaging spectrum and management.
Akahane M, Koga H, Kato N, Yamada H, Uozumi K, Tateishi R, Teratani T, Shiina S, Ohtomo K
Radiographics 2005 Oct;25 Suppl 1:S57-68. doi: 10.1148/rg.25si055505. PMID: 16227497
Hepatic disease in pregnancy.
Riely CA
Am J Med 1994 Jan 17;96(1A):18S-22S. doi: 10.1016/0002-9343(94)90185-6. PMID: 8109583

Diagnosis

Liver involvement in patients with COVID-19 infection: A comprehensive overview of diagnostic imaging features.
Ippolito D, Maino C, Vernuccio F, Cannella R, Inchingolo R, Dezio M, Faletti R, Bonaffini PA, Gatti M, Sironi S
World J Gastroenterol 2023 Feb 7;29(5):834-850. doi: 10.3748/wjg.v29.i5.834. PMID: 36816623Free PMC Article
Liver stiffness and steatosis in preeclampsia as shown by transient elastography-a prospective cohort study.
Carmiel Haggai M, Sgayer I, Bornstein J, Odeh M, Lowenstein L, Frank Wolf M
Am J Obstet Gynecol 2022 Sep;227(3):515.e1-515.e9. Epub 2022 Apr 29 doi: 10.1016/j.ajog.2022.04.048. PMID: 35500613
Eculizumab for refractory thrombosis in antiphospholipid syndrome.
Hussain H, Tarantino MD, Chaturvedi S, McCrae KR, Roberts JC
Blood Adv 2022 Feb 22;6(4):1271-1277. doi: 10.1182/bloodadvances.2021005657. PMID: 35051999Free PMC Article
CT after pancreaticoduodenectomy: spectrum of normal findings and complications.
Raman SP, Horton KM, Cameron JL, Fishman EK
AJR Am J Roentgenol 2013 Jul;201(1):2-13. doi: 10.2214/AJR.12.9647. PMID: 23789653
Unusual causes of abdominal pain: sickle cell anemia.
Ahmed S, Shahid RK, Russo LA
Best Pract Res Clin Gastroenterol 2005 Apr;19(2):297-310. doi: 10.1016/j.bpg.2004.11.007. PMID: 15833695

Therapy

Eculizumab for refractory thrombosis in antiphospholipid syndrome.
Hussain H, Tarantino MD, Chaturvedi S, McCrae KR, Roberts JC
Blood Adv 2022 Feb 22;6(4):1271-1277. doi: 10.1182/bloodadvances.2021005657. PMID: 35051999Free PMC Article
Pterostilbene alleviates liver ischemia/reperfusion injury via PINK1-mediated mitophagy.
Shi Q, Zhao G, Wei S, Guo C, Wu X, Zhao RC, Di G
J Pharmacol Sci 2022 Jan;148(1):19-30. Epub 2021 Sep 23 doi: 10.1016/j.jphs.2021.09.005. PMID: 34924126
Biodistribution and radiation dosimetry of radioiodinated hypericin as a cancer therapeutic.
Cona MM, Koole M, Feng Y, Liu Y, Verbruggen A, Oyen R, Ni Y
Int J Oncol 2014 Mar;44(3):819-29. Epub 2013 Dec 17 doi: 10.3892/ijo.2013.2217. PMID: 24366374
Complications of percutaneous radiofrequency ablation for hepato-cellular carcinoma: imaging spectrum and management.
Akahane M, Koga H, Kato N, Yamada H, Uozumi K, Tateishi R, Teratani T, Shiina S, Ohtomo K
Radiographics 2005 Oct;25 Suppl 1:S57-68. doi: 10.1148/rg.25si055505. PMID: 16227497
Low-molecular-weight heparins in pregnancy.
Ensom MH, Stephenson MD
Pharmacotherapy 1999 Sep;19(9):1013-25. doi: 10.1592/phco.19.13.1013.31588. PMID: 10610007

Prognosis

Liver stiffness and steatosis in preeclampsia as shown by transient elastography-a prospective cohort study.
Carmiel Haggai M, Sgayer I, Bornstein J, Odeh M, Lowenstein L, Frank Wolf M
Am J Obstet Gynecol 2022 Sep;227(3):515.e1-515.e9. Epub 2022 Apr 29 doi: 10.1016/j.ajog.2022.04.048. PMID: 35500613
Percutaneous cryoablation for perivascular hepatocellular carcinoma: Therapeutic efficacy and vascular complications.
Kim R, Kang TW, Cha DI, Song KD, Lee MW, Rhim H, Lim HK, Sinn DH
Eur Radiol 2019 Feb;29(2):654-662. Epub 2018 Jul 24 doi: 10.1007/s00330-018-5617-6. PMID: 30043160
Short-term effectiveness of radiochemoembolization for selected hepatic metastases with a combination protocol.
Akhlaghpoor S, Aziz-Ahari A, Amoui M, Tolooee S, Poorbeigi H, Sheybani S
World J Gastroenterol 2012 Oct 7;18(37):5249-59. doi: 10.3748/wjg.v18.i37.5249. PMID: 23066320Free PMC Article
Styrene maleic acid neocarzinostatin treatment for hepatocellular carcinoma.
Abe S, Otsuki M
Curr Med Chem Anticancer Agents 2002 Nov;2(6):715-26. doi: 10.2174/1568011023353679. PMID: 12678722
Liver disease in pregnancy.
Hunt CM, Sharara AI
Am Fam Physician 1999 Feb 15;59(4):829-36. PMID: 10068707

Clinical prediction guides

Hepatic infarction in pregnancy: a systematic review.
Munter BT, Boyd AR, Tchani R, Gray JN, Ramsey PS
Am J Obstet Gynecol MFM 2024 Jun;6(6):101377. Epub 2024 Apr 14 doi: 10.1016/j.ajogmf.2024.101377. PMID: 38621440
Liver stiffness and steatosis in preeclampsia as shown by transient elastography-a prospective cohort study.
Carmiel Haggai M, Sgayer I, Bornstein J, Odeh M, Lowenstein L, Frank Wolf M
Am J Obstet Gynecol 2022 Sep;227(3):515.e1-515.e9. Epub 2022 Apr 29 doi: 10.1016/j.ajog.2022.04.048. PMID: 35500613
Venous thrombosis and segmental hypoperfusion in amebic liver abscess: MDCT demonstration and its implications.
Priyadarshi RN, Kumar P, Kumar R, Anand U, Shyama
Abdom Radiol (NY) 2020 Mar;45(3):652-660. doi: 10.1007/s00261-020-02409-6. PMID: 31955219
Biodistribution and radiation dosimetry of radioiodinated hypericin as a cancer therapeutic.
Cona MM, Koole M, Feng Y, Liu Y, Verbruggen A, Oyen R, Ni Y
Int J Oncol 2014 Mar;44(3):819-29. Epub 2013 Dec 17 doi: 10.3892/ijo.2013.2217. PMID: 24366374
Complications of percutaneous radiofrequency ablation for hepato-cellular carcinoma: imaging spectrum and management.
Akahane M, Koga H, Kato N, Yamada H, Uozumi K, Tateishi R, Teratani T, Shiina S, Ohtomo K
Radiographics 2005 Oct;25 Suppl 1:S57-68. doi: 10.1148/rg.25si055505. PMID: 16227497

Recent systematic reviews

Hepatic infarction in pregnancy: a systematic review.
Munter BT, Boyd AR, Tchani R, Gray JN, Ramsey PS
Am J Obstet Gynecol MFM 2024 Jun;6(6):101377. Epub 2024 Apr 14 doi: 10.1016/j.ajogmf.2024.101377. PMID: 38621440
Low-molecular-weight heparins in pregnancy.
Ensom MH, Stephenson MD
Pharmacotherapy 1999 Sep;19(9):1013-25. doi: 10.1592/phco.19.13.1013.31588. PMID: 10610007

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