U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Complete bilateral cleft lip

MedGen UID:
510612
•Concept ID:
C0158653
•
Congenital Abnormality
Synonym: Cleft lip, bilateral complete
SNOMED CT: Bilateral complete cleft lip (80446009); Complete bilateral cleft lip (80446009)
 
HPO: HP:5201011

Definition

Bilateral cleft lip in which the cleft lip on both sides is complete, i.e. start from the bottom of the upper lip and reach the nasal cavity. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVComplete bilateral cleft lip

Professional guidelines

PubMed

Long-term treatment outcome of patients with complete bilateral cleft lip and palate: a retrospective cohort study.
Hattori Y, Pai BC, Saito T, Chou PY, Lu TC, Chang CS, Chen YR, Lo LJ
Int J Surg 2023 Jun 1;109(6):1656-1667. doi: 10.1097/JS9.0000000000000406. PMID: 37073546Free PMC Article
Clinical Finding and Management of 12 Orofacial Clefts Cases With Nevoid Basal Cell Carcinoma Syndrome.
Mui Lee L, Ma L, Jun Li T
Cleft Palate Craniofac J 2017 May;54(3):338-342. doi: 10.1597/14-323. PMID: 28471735
Primary repair of bilateral cleft lip and nasal deformity.
Mulliken JB
Plast Reconstr Surg 2001 Jul;108(1):181-94; examination,195-6. doi: 10.1097/00006534-200107000-00028. PMID: 11420522

Recent clinical studies

Etiology

"Challenges and concerns faced by parents of a group of Egyptian children with cleft lip/palate: a qualitative study".
Morsi AO, Yehia AM, Badran AS, Khattab NMA
BMC Oral Health 2023 Dec 16;23(1):1011. doi: 10.1186/s12903-023-03747-9. PMID: 38104058Free PMC Article
Long-term treatment outcome of patients with complete bilateral cleft lip and palate: a retrospective cohort study.
Hattori Y, Pai BC, Saito T, Chou PY, Lu TC, Chang CS, Chen YR, Lo LJ
Int J Surg 2023 Jun 1;109(6):1656-1667. doi: 10.1097/JS9.0000000000000406. PMID: 37073546Free PMC Article
Extensive Gingivoperiosteoplasty Versus Secondary Alveolar Bone Grafting in Patients With Complete Bilateral Cleft Lip and Palate During the Mixed Dentition Period: A Retrospective Outcome Analysis.
Lu TC, Bhandari K, Yao CF, Tangco I, Bajracharya M, Chen PK
Ann Plast Surg 2022 Mar 1;88(1s Suppl 1):S27-S32. doi: 10.1097/SAP.0000000000003118. PMID: 35225845
An anatomical subunit-based outcome assessment scale for bilateral cleft lip and palate.
Bonanthaya K, Shetty PN, Fudalej PS, Rao DD, Bitra S, Pabari M, Rachwalski M
Int J Oral Maxillofac Surg 2017 Aug;46(8):988-992. Epub 2017 Apr 10 doi: 10.1016/j.ijom.2017.03.021. PMID: 28408147
Tooth agenesis patterns in bilateral cleft lip and palate.
Bartzela TN, Carels CE, Bronkhorst EM, Rønning E, Rizell S, Kuijpers-Jagtman AM
Eur J Oral Sci 2010 Feb;118(1):47-52. doi: 10.1111/j.1600-0722.2009.00698.x. PMID: 20156264

Diagnosis

Interdisciplinary Approach for the Treatment of Complex Bilateral Cleft Lip and Palate With Missing Premaxilla.
Park YJ, Derderian C, Oppedisano M
Cleft Palate Craniofac J 2022 May;59(5):680-687. Epub 2021 Jun 23 doi: 10.1177/10556656211023241. PMID: 34159818
Premaxillary Setback With Posterior Vomerine Ostectomy: Outcomes of Single-Stage Repair of Complete Bilateral Cleft Lip With a Severely Protruding Premaxilla.
Almas F, Cote V, Ramly EP, Kantar RS, Hamdan U
Cleft Palate Craniofac J 2019 Apr;56(4):471-478. Epub 2018 Jun 21 doi: 10.1177/1055665618782806. PMID: 29927627
Popliteal Pterygium Syndrome With Syngnathia.
Sisti A, Freda N, Giacomina A, Gatti GL
J Craniofac Surg 2017 May;28(3):e250-e251. doi: 10.1097/SCS.0000000000003473. PMID: 28468208
Nasalance measures in German-speaking cleft patients.
Swennen GR, Grimaldi H, Upheber J, Kramer FJ, Dempf R
J Craniofac Surg 2004 Jan;15(1):158-64; discussion 164. doi: 10.1097/00001665-200401000-00038. PMID: 14704583
Craniofacial morphology in adults with bilateral complete cleft lip and palate.
Smahel Z
Cleft Palate J 1984 Jul;21(3):159-69. PMID: 6592058

Therapy

Treatment Outcome in Bilateral Cleft lip and Palate Patients Evaluated With the Huddart-Bodenham Scoring System and the Bilateral Cleft lip and Palate Yardstick: A Systematic Review.
Kuang W, Aarts M, Kuijpers-Jagtman AM, He H, Ongkosuwito EM
Cleft Palate Craniofac J 2022 Nov;59(11):1377-1390. Epub 2021 Oct 18 doi: 10.1177/10556656211041883. PMID: 34658258Free PMC Article
Reconstruction of Major Dehiscence After Bilateral Cleft Lip Repair.
Lim E, Pai BCJ, Getachew D, Jung S, Lo LJ
J Craniofac Surg 2018 Nov;29(8):2211-2213. doi: 10.1097/SCS.0000000000004989. PMID: 30320692
Slow versus rapid maxillary expansion in bilateral cleft lip and palate: a CBCT randomized clinical trial.
de Almeida AM, Ozawa TO, Alves ACM, Janson G, Lauris JRP, Ioshida MSY, Garib DG
Clin Oral Investig 2017 Jun;21(5):1789-1799. Epub 2016 Aug 22 doi: 10.1007/s00784-016-1943-8. PMID: 27550292
Interdisciplinary treatment of an adult with complete bilateral cleft lip and palate.
Okada W, Fukui T, Saito T, Ohkubo C, Hamada Y, Nakamura Y
Am J Orthod Dentofacial Orthop 2012 Apr;141(4 Suppl):S149-58. doi: 10.1016/j.ajodo.2011.07.025. PMID: 22449595
Speech in unilateral and bilateral cleft palate patients from Stockholm.
Karling J, Larson O, Leanderson R, Henningsson G
Cleft Palate Craniofac J 1993 Jan;30(1):73-7. doi: 10.1597/1545-1569_1993_030_0073_siuabc_2.3.co_2. PMID: 8418875

Prognosis

Validating the Asher-McDade score to assess facial aesthetic outcomes in 22 consecutive complete bilateral cleft lip repairs.
Thomson RM, Azzopardi E, Drake D
Br J Oral Maxillofac Surg 2021 Apr;59(3):375-379. Epub 2020 Sep 11 doi: 10.1016/j.bjoms.2020.09.001. PMID: 33349494
A comparative study of two different techniques for complete bilateral cleft lip repair using two-dimensional photographic analysis.
Reddy SG, Reddy RR, Zinser MJ, Reddy LV, Markus AF, Bergé SJ
Plast Reconstr Surg 2013 Sep;132(3):634-642. doi: 10.1097/PRS.0b013e31829ad193. PMID: 23985638
Effects of presurgical orthopedic treatment in infants with complete bilateral cleft lip and palate.
Mishima K, Sugahara T, Mori Y, Minami K, Sakuda M
Cleft Palate Craniofac J 1998 May;35(3):227-32. doi: 10.1597/1545-1569_1998_035_0227_eopoti_2.3.co_2. PMID: 9603557
Palatal configuration in complete bilateral cleft lip and palate infants before and after cheiloplasty.
Mishima K, Sugahara T, Mori Y, Sakuda M
Cleft Palate Craniofac J 1997 Nov;34(6):475-82. doi: 10.1597/1545-1569_1997_034_0475_pcicbc_2.3.co_2. PMID: 9431464
Craniofacial morphology in adults with bilateral complete cleft lip and palate.
Smahel Z
Cleft Palate J 1984 Jul;21(3):159-69. PMID: 6592058

Clinical prediction guides

Treatment Outcome in Bilateral Cleft lip and Palate Patients Evaluated With the Huddart-Bodenham Scoring System and the Bilateral Cleft lip and Palate Yardstick: A Systematic Review.
Kuang W, Aarts M, Kuijpers-Jagtman AM, He H, Ongkosuwito EM
Cleft Palate Craniofac J 2022 Nov;59(11):1377-1390. Epub 2021 Oct 18 doi: 10.1177/10556656211041883. PMID: 34658258Free PMC Article
Validating the Asher-McDade score to assess facial aesthetic outcomes in 22 consecutive complete bilateral cleft lip repairs.
Thomson RM, Azzopardi E, Drake D
Br J Oral Maxillofac Surg 2021 Apr;59(3):375-379. Epub 2020 Sep 11 doi: 10.1016/j.bjoms.2020.09.001. PMID: 33349494
An anatomical subunit-based outcome assessment scale for bilateral cleft lip and palate.
Bonanthaya K, Shetty PN, Fudalej PS, Rao DD, Bitra S, Pabari M, Rachwalski M
Int J Oral Maxillofac Surg 2017 Aug;46(8):988-992. Epub 2017 Apr 10 doi: 10.1016/j.ijom.2017.03.021. PMID: 28408147
Slow versus rapid maxillary expansion in bilateral cleft lip and palate: a CBCT randomized clinical trial.
de Almeida AM, Ozawa TO, Alves ACM, Janson G, Lauris JRP, Ioshida MSY, Garib DG
Clin Oral Investig 2017 Jun;21(5):1789-1799. Epub 2016 Aug 22 doi: 10.1007/s00784-016-1943-8. PMID: 27550292
Tooth agenesis patterns in bilateral cleft lip and palate.
Bartzela TN, Carels CE, Bronkhorst EM, Rønning E, Rizell S, Kuijpers-Jagtman AM
Eur J Oral Sci 2010 Feb;118(1):47-52. doi: 10.1111/j.1600-0722.2009.00698.x. PMID: 20156264

Recent systematic reviews

Treatment Outcome in Bilateral Cleft lip and Palate Patients Evaluated With the Huddart-Bodenham Scoring System and the Bilateral Cleft lip and Palate Yardstick: A Systematic Review.
Kuang W, Aarts M, Kuijpers-Jagtman AM, He H, Ongkosuwito EM
Cleft Palate Craniofac J 2022 Nov;59(11):1377-1390. Epub 2021 Oct 18 doi: 10.1177/10556656211041883. PMID: 34658258Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...