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Pancreatic abscess

MedGen UID:
536797
•Concept ID:
C0238334
•
Disease or Syndrome
Synonyms: Abscess of pancreas; Pancreas abscess
SNOMED CT: Abscess of pancreas (69643006); Pancreatic abscess (69643006)
 
HPO: HP:0025079

Definition

A circumscribed area of pus or necrotic debris in the parenchyma of the pancreas. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPancreatic abscess

Professional guidelines

PubMed

Severe acute pancreatitis: Clinical course and management.
Beger HG, Rau BM
World J Gastroenterol 2007 Oct 14;13(38):5043-51. doi: 10.3748/wjg.v13.i38.5043. PMID: 17876868Free PMC Article
Management of fluid collections and necrosis in acute pancreatitis.
Tsiotos GG, Sarr MG
Curr Gastroenterol Rep 1999 Apr;1(2):139-44. doi: 10.1007/s11894-996-0013-9. PMID: 10980941
Surgical management of acute pancreatitis.
Martin JK Jr, van Heerden JA, Bess MA
Mayo Clin Proc 1984 Apr;59(4):259-67. doi: 10.1016/s0025-6196(12)61260-9. PMID: 6369015

Recent clinical studies

Etiology

Impact of low-molecular-weight heparin in the treatment of moderately severe and severe acute pancreatitis; a randomized, single blind, phase 3 control trial.
Patil B, Meena LN, Sharma DC, Agarwal G, Dadhich Y, Gupta G
Int J Surg 2022 May;101:106621. Epub 2022 Apr 27 doi: 10.1016/j.ijsu.2022.106621. PMID: 35489648
Drainage after distal pancreatectomy: Still an unsolved problem.
Machado MCC, Machado MAC
Surg Oncol 2019 Sep;30:76-80. Epub 2019 Jun 5 doi: 10.1016/j.suronc.2019.06.002. PMID: 31500790
The microbiology of infected pancreatic necrosis.
Mowbray NG, Ben-Ismaeil B, Hammoda M, Shingler G, Al-Sarireh B
Hepatobiliary Pancreat Dis Int 2018 Oct;17(5):456-460. Epub 2018 Aug 29 doi: 10.1016/j.hbpd.2018.08.007. PMID: 30197163
Severe acute pancreatitis: Clinical course and management.
Beger HG, Rau BM
World J Gastroenterol 2007 Oct 14;13(38):5043-51. doi: 10.3748/wjg.v13.i38.5043. PMID: 17876868Free PMC Article
Acute and chronic pancreatitis.
Davenport M
Indian J Pediatr 2002 Sep;69(9):801-7. doi: 10.1007/BF02723695. PMID: 12420914

Diagnosis

Drainage after distal pancreatectomy: Still an unsolved problem.
Machado MCC, Machado MAC
Surg Oncol 2019 Sep;30:76-80. Epub 2019 Jun 5 doi: 10.1016/j.suronc.2019.06.002. PMID: 31500790
The microbiology of infected pancreatic necrosis.
Mowbray NG, Ben-Ismaeil B, Hammoda M, Shingler G, Al-Sarireh B
Hepatobiliary Pancreat Dis Int 2018 Oct;17(5):456-460. Epub 2018 Aug 29 doi: 10.1016/j.hbpd.2018.08.007. PMID: 30197163
Revised Atlanta Classification for Acute Pancreatitis: A Pictorial Essay.
Foster BR, Jensen KK, Bakis G, Shaaban AM, Coakley FV
Radiographics 2016 May-Jun;36(3):675-87. doi: 10.1148/rg.2016150097. PMID: 27163588
Severe colonic complications of pancreatic disease.
Gardner A, Gardner G, Feller E
J Clin Gastroenterol 2003 Sep;37(3):258-62. doi: 10.1097/00004836-200309000-00012. PMID: 12960726
Acute pancreatitis.
Geokas MC
Calif Med 1972 Aug;117(2):25-39. PMID: 4559467Free PMC Article

Therapy

Impact of low-molecular-weight heparin in the treatment of moderately severe and severe acute pancreatitis; a randomized, single blind, phase 3 control trial.
Patil B, Meena LN, Sharma DC, Agarwal G, Dadhich Y, Gupta G
Int J Surg 2022 May;101:106621. Epub 2022 Apr 27 doi: 10.1016/j.ijsu.2022.106621. PMID: 35489648
Drainage after distal pancreatectomy: Still an unsolved problem.
Machado MCC, Machado MAC
Surg Oncol 2019 Sep;30:76-80. Epub 2019 Jun 5 doi: 10.1016/j.suronc.2019.06.002. PMID: 31500790
The microbiology of infected pancreatic necrosis.
Mowbray NG, Ben-Ismaeil B, Hammoda M, Shingler G, Al-Sarireh B
Hepatobiliary Pancreat Dis Int 2018 Oct;17(5):456-460. Epub 2018 Aug 29 doi: 10.1016/j.hbpd.2018.08.007. PMID: 30197163
Isolated Pancreatic Tuberculosis in an Immunocompetent Host.
Singhai P, Gadhadh R, Joshi S, Krishnan S, Aparna
J Assoc Physicians India 2017 Dec;65(12):98-100. PMID: 29327531
Asian consensus statements on endoscopic management of walled-off necrosis. Part 2: Endoscopic management.
Isayama H, Nakai Y, Rerknimitr R, Khor C, Lau J, Wang HP, Seo DW, Ratanachu-Ek T, Lakhtakia S, Ang TL, Ryozawa S, Hayashi T, Kawakami H, Yamamoto N, Iwashita T, Itokawa F, Kuwatani M, Kitano M, Hanada K, Kogure H, Hamada T, Ponnudurai R, Moon JH, Itoi T, Yasuda I, Irisawa A, Maetani I
J Gastroenterol Hepatol 2016 Sep;31(9):1555-65. doi: 10.1111/jgh.13398. PMID: 27042957

Prognosis

Acute pancreatitis: an update on the revised Atlanta classification.
Colvin SD, Smith EN, Morgan DE, Porter KK
Abdom Radiol (NY) 2020 May;45(5):1222-1231. doi: 10.1007/s00261-019-02214-w. PMID: 31494708
Drainage after distal pancreatectomy: Still an unsolved problem.
Machado MCC, Machado MAC
Surg Oncol 2019 Sep;30:76-80. Epub 2019 Jun 5 doi: 10.1016/j.suronc.2019.06.002. PMID: 31500790
The microbiology of infected pancreatic necrosis.
Mowbray NG, Ben-Ismaeil B, Hammoda M, Shingler G, Al-Sarireh B
Hepatobiliary Pancreat Dis Int 2018 Oct;17(5):456-460. Epub 2018 Aug 29 doi: 10.1016/j.hbpd.2018.08.007. PMID: 30197163
Asian consensus statements on endoscopic management of walled-off necrosis. Part 2: Endoscopic management.
Isayama H, Nakai Y, Rerknimitr R, Khor C, Lau J, Wang HP, Seo DW, Ratanachu-Ek T, Lakhtakia S, Ang TL, Ryozawa S, Hayashi T, Kawakami H, Yamamoto N, Iwashita T, Itokawa F, Kuwatani M, Kitano M, Hanada K, Kogure H, Hamada T, Ponnudurai R, Moon JH, Itoi T, Yasuda I, Irisawa A, Maetani I
J Gastroenterol Hepatol 2016 Sep;31(9):1555-65. doi: 10.1111/jgh.13398. PMID: 27042957
Acute and chronic pancreatitis.
Davenport M
Indian J Pediatr 2002 Sep;69(9):801-7. doi: 10.1007/BF02723695. PMID: 12420914

Clinical prediction guides

Drainage after distal pancreatectomy: Still an unsolved problem.
Machado MCC, Machado MAC
Surg Oncol 2019 Sep;30:76-80. Epub 2019 Jun 5 doi: 10.1016/j.suronc.2019.06.002. PMID: 31500790
Efficacy and drug resistance of antibacterials in patients' with acute pancreatitis and stress ulcer bleeding.
Li J, Meng L, Zhang H, Wang X
Pak J Pharm Sci 2017 Sep;30(5(Special)):1905-1909. PMID: 29084665
Clinical significance of serum triglyceride elevation at early stage of acute biliary pancreatitis.
Cheng L, Luo Z, Xiang K, Ren J, Huang Z, Tang L, Tian F
BMC Gastroenterol 2015 Feb 14;15:19. doi: 10.1186/s12876-015-0254-x. PMID: 25887309Free PMC Article
Meta-Analysis of Early Endoscopic Retrograde Cholangiopancreatography (ERCP) ± Endoscopic Sphincterotomy (ES) Versus Conservative Management for Gallstone Pancreatitis (GSP).
Burstow MJ, Yunus RM, Hossain MB, Khan S, Memon B, Memon MA
Surg Laparosc Endosc Percutan Tech 2015 Jun;25(3):185-203. doi: 10.1097/SLE.0000000000000142. PMID: 25799261
Microbial resistance surveillance techniques. Blood culture versus multiple body site monitoring.
Koontz FP
Diagn Microbiol Infect Dis 1992 Feb;15(2 Suppl):31S-35S. PMID: 1737441

Recent systematic reviews

Open necrosectomy is feasible as a last resort in selected cases with infected pancreatic necrosis: a case series and systematic literature review.
Sgaramella LI, Gurrado A, Pasculli A, Prete FP, Catena F, Testini M
World J Emerg Surg 2020 Jul 29;15(1):44. doi: 10.1186/s13017-020-00326-z. PMID: 32727508Free PMC Article
Minimally invasive management of pancreatic abscess, pseudocyst, and necrosis: a systematic review of current guidelines.
Loveday BP, Mittal A, Phillips A, Windsor JA
World J Surg 2008 Nov;32(11):2383-94. doi: 10.1007/s00268-008-9701-y. PMID: 18670801

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