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Rectosigmoid junction cancer

MedGen UID:
57558
•Concept ID:
C0153443
•
Neoplastic Process
Synonyms: cancer of rectosigmoid junction; malignant neoplasm of rectosigmoid; Malignant Neoplasm of Rectosigmoid Junction; malignant neoplasm of rectosigmoid junction; Malignant Neoplasm of the Rectosigmoid Junction; malignant neoplasm of the rectosigmoid junction; malignant rectosigmoid junction neoplasm; Malignant Rectosigmoid Neoplasm; malignant rectosigmoid neoplasm; Malignant Rectosigmoid Tumor; malignant rectosigmoid tumor; malignant rectosigmoid tumour; Malignant tumor of rectosigmoid junction; Malignant Tumor of Rectosigmoid Junction; malignant tumor of rectosigmoid junction; Malignant Tumor of the Rectosigmoid Junction; malignant tumor of the rectosigmoid junction; malignant tumour of rectosigmoid junction; malignant tumour of the rectosigmoid junction; Rectosigmoid colon cancer; rectosigmoid junction cancer
SNOMED CT: Rectosigmoid colon cancer (363414004); Malignant tumor of rectosigmoid junction (363414004)
 
Monarch Initiative: MONDO:0002425

Definition

A primary or metastatic malignant neoplasm that affects the rectosigmoid area. Representative examples include carcinoma, lymphoma, and sarcoma. [from NCI]

Professional guidelines

PubMed

Risk factors and management of iatrogenic colorectal perforation in diagnostic colonoscopy: a single-center cohort study.
Kim A, Kim H, Kim ER, Kim JE, Hong SN, Chang DK, Kim YH
Scand J Gastroenterol 2024 Jun;59(6):749-754. Epub 2024 Feb 21 doi: 10.1080/00365521.2024.2316766. PMID: 38380637
Comparative Effectiveness of Neoadjuvant Chemoradiation Versus Upfront Surgery in the Management of Recto-Sigmoid Junction Cancer.
Venigalla S, Chowdhry AK, Wojcieszynski AP, Lukens JN, Plastaras JP, Metz JM, Ben-Josef E, Mahmoud NN, Reiss KA, Shabason JE
Clin Colorectal Cancer 2018 Sep;17(3):e557-e568. Epub 2018 May 17 doi: 10.1016/j.clcc.2018.05.005. PMID: 29910004Free PMC Article
Colorectal cancer incidence and survival by sub-site and stage of diagnosis: a population-based study at the advent of national screening.
McDevitt J, Comber H, Walsh PM
Ir J Med Sci 2017 Feb;186(1):113-121. Epub 2016 Oct 18 doi: 10.1007/s11845-016-1513-8. PMID: 27752924

Recent clinical studies

Etiology

A postsurgical prognostic nomogram for patients with lymph node positive rectosigmoid junction adenocarcinoma.
Yanlong W, Yunxiao W, Yibing W
BMC Gastroenterol 2023 May 18;23(1):159. doi: 10.1186/s12876-023-02810-7. PMID: 37202718Free PMC Article
Laparoscopic-Assisted Resection for Advanced Colorectal Cancer in Solid Organ Transplant Recipients.
Xia ZN, Hou R, Zhu W, Yao R, Lu Z, Qiu HZ, Lin GL
J Invest Surg 2018 Dec;31(6):483-490. Epub 2017 Sep 19 doi: 10.1080/08941939.2017.1359707. PMID: 28925783
Reduced Ovarian Cancer Incidence in Women Exposed to Low Dose Ionizing Background Radiation or Radiation to the Ovaries after Treatment for Breast Cancer or Rectosigmoid Cancer.
Lehrer S, Green S, Rosenzweig KE
Asian Pac J Cancer Prev 2016;17(6):2979-82. PMID: 27356721Free PMC Article
Stage II/III cancer of the rectosigmoid junction: an independent tumor type?
Mukai M, Kishima K, Yamazaki M, Aoki H, Izumi H, Yamamoto S, Tajima T, Tobita K, Sadahiro S, Yasuda S, Ogoshi K
Oncol Rep 2011 Sep;26(3):737-41. Epub 2011 Jun 8 doi: 10.3892/or.2011.1343. PMID: 21667035
A case-control study of relationships of diet and other traits to colorectal cancer in American blacks.
Dales LG, Friedman GD, Ury HK, Grossman S, Williams SR
Am J Epidemiol 1979 Feb;109(2):132-44. doi: 10.1093/oxfordjournals.aje.a112668. PMID: 425952

Diagnosis

Radiation Oncologists' Approach to Rectosigmoid Junction Tumors in Turkey: The Turkish Society for Radiation Oncology Gastrointestinal Group Survey Study (TROD 02-007).
Aynacı Ö, Serdar L, Canyılmaz E, Hürmüz P
Turk J Gastroenterol 2023 Sep;34(9):911-917. doi: 10.5152/tjg.2023.22597. PMID: 37458391Free PMC Article
Cancer of the Rectum and Rectosigmoid Junction: 20-Year Comparative Survival and Mortality Analysis by Age, Sex, Race, Stage, Grade, Cohort Entry Time-Period and Disease Duration: A Systematic Review of 266,898 Cases for Diagnosis Years 1973-2014: (SEER*Stat 8.3.4).
Milano AF
J Insur Med 2022 Jul 1;49(3):126-146. doi: 10.17849/insm-49-3-126-146.1. PMID: 36378889
Radiotherapy dose led to a substantial prolongation of survival in patients with locally advanced rectosigmoid junction cancer: a large population based study.
Guan X, Jiang Z, Ma T, Liu Z, Hu H, Zhao Z, Song D, Chen Y, Wang G, Wang X
Oncotarget 2016 May 10;7(19):28408-19. doi: 10.18632/oncotarget.8630. PMID: 27070089Free PMC Article

Therapy

Cancer risks in a population-based study of agricultural workers: results from the Taiwan's Farmers and Health Cohort study.
Chen WL, Lin GL, Lin YJ, Su TY, Wang CC, Wu WT
Scand J Work Environ Health 2023 Sep 1;49(6):419-427. Epub 2023 Jul 14 doi: 10.5271/sjweh.4106. PMID: 37449304Free PMC Article
A postsurgical prognostic nomogram for patients with lymph node positive rectosigmoid junction adenocarcinoma.
Yanlong W, Yunxiao W, Yibing W
BMC Gastroenterol 2023 May 18;23(1):159. doi: 10.1186/s12876-023-02810-7. PMID: 37202718Free PMC Article
Laparoscopic-Assisted Resection for Advanced Colorectal Cancer in Solid Organ Transplant Recipients.
Xia ZN, Hou R, Zhu W, Yao R, Lu Z, Qiu HZ, Lin GL
J Invest Surg 2018 Dec;31(6):483-490. Epub 2017 Sep 19 doi: 10.1080/08941939.2017.1359707. PMID: 28925783
Radiotherapy dose led to a substantial prolongation of survival in patients with locally advanced rectosigmoid junction cancer: a large population based study.
Guan X, Jiang Z, Ma T, Liu Z, Hu H, Zhao Z, Song D, Chen Y, Wang G, Wang X
Oncotarget 2016 May 10;7(19):28408-19. doi: 10.18632/oncotarget.8630. PMID: 27070089Free PMC Article

Prognosis

A postsurgical prognostic nomogram for patients with lymph node positive rectosigmoid junction adenocarcinoma.
Yanlong W, Yunxiao W, Yibing W
BMC Gastroenterol 2023 May 18;23(1):159. doi: 10.1186/s12876-023-02810-7. PMID: 37202718Free PMC Article
Colorectal Intussusception Due to Rectosigmoid Junction Cancer: A Unique Surgical Challenge?
Lianos GD, Drosou P, Souvatzoglou R, Vangelis G, Mitsis M, Lekkas E
J Gastrointest Cancer 2020 Jun;51(2):639-642. doi: 10.1007/s12029-019-00326-6. PMID: 31713812
Laparoscopic-Assisted Resection for Advanced Colorectal Cancer in Solid Organ Transplant Recipients.
Xia ZN, Hou R, Zhu W, Yao R, Lu Z, Qiu HZ, Lin GL
J Invest Surg 2018 Dec;31(6):483-490. Epub 2017 Sep 19 doi: 10.1080/08941939.2017.1359707. PMID: 28925783
Reduced Ovarian Cancer Incidence in Women Exposed to Low Dose Ionizing Background Radiation or Radiation to the Ovaries after Treatment for Breast Cancer or Rectosigmoid Cancer.
Lehrer S, Green S, Rosenzweig KE
Asian Pac J Cancer Prev 2016;17(6):2979-82. PMID: 27356721Free PMC Article
Radiotherapy dose led to a substantial prolongation of survival in patients with locally advanced rectosigmoid junction cancer: a large population based study.
Guan X, Jiang Z, Ma T, Liu Z, Hu H, Zhao Z, Song D, Chen Y, Wang G, Wang X
Oncotarget 2016 May 10;7(19):28408-19. doi: 10.18632/oncotarget.8630. PMID: 27070089Free PMC Article

Clinical prediction guides

Radiation Oncologists' Approach to Rectosigmoid Junction Tumors in Turkey: The Turkish Society for Radiation Oncology Gastrointestinal Group Survey Study (TROD 02-007).
Aynacı Ö, Serdar L, Canyılmaz E, Hürmüz P
Turk J Gastroenterol 2023 Sep;34(9):911-917. doi: 10.5152/tjg.2023.22597. PMID: 37458391Free PMC Article
A postsurgical prognostic nomogram for patients with lymph node positive rectosigmoid junction adenocarcinoma.
Yanlong W, Yunxiao W, Yibing W
BMC Gastroenterol 2023 May 18;23(1):159. doi: 10.1186/s12876-023-02810-7. PMID: 37202718Free PMC Article
Radiotherapy dose led to a substantial prolongation of survival in patients with locally advanced rectosigmoid junction cancer: a large population based study.
Guan X, Jiang Z, Ma T, Liu Z, Hu H, Zhao Z, Song D, Chen Y, Wang G, Wang X
Oncotarget 2016 May 10;7(19):28408-19. doi: 10.18632/oncotarget.8630. PMID: 27070089Free PMC Article

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