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Benign Seminal Vesicle Neoplasm

MedGen UID:
577309
•Concept ID:
C0346217
•
Neoplastic Process
Synonyms: Benign neoplasm of seminal vesicle; Benign tumor of seminal vesicle
SNOMED CT: Benign tumor of seminal vesicle (189140003); Benign neoplasm of seminal vesicle (189140003)

Definition

A neoplasm that arises from the seminal vesicle and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Professional guidelines

PubMed

Diagnosis and Treatment of a Mixed Epithelial Stromal Tumor of the Seminal Vesicle: A Systematic Review.
Babar M, Matloubieh J, Macdonald E, Cheng J, Aboumohamed A, Watts K
Urology 2022 Sep;167:13-18. Epub 2022 Feb 26 doi: 10.1016/j.urology.2022.02.012. PMID: 35231450
Effectiveness and Safety of Prostatic Artery Embolization for the Treatment of Lower Urinary Tract Symptoms from Benign Prostatic Hyperplasia in Men with Concurrent Localized Prostate Cancer.
Parikh N, Keshishian E, Manley B, Grass GD, Torres-Roca J, Boulware D, Feuerlein S, Pow-Sang JM, Bagla S, Yamoah K, Bhatia S
J Vasc Interv Radiol 2021 Jul;32(7):1053-1061. Epub 2021 Mar 29 doi: 10.1016/j.jvir.2021.03.534. PMID: 33794373
Diagnosis and management of local recurrence after low-dose-rate brachytherapy.
Stone NN, Unger P, Crawford ED, Stock RG
Brachytherapy 2015 Mar-Apr;14(2):124-30. Epub 2014 Sep 16 doi: 10.1016/j.brachy.2014.08.046. PMID: 25239396

Recent clinical studies

Etiology

Tandem histone methyltransferase upregulation defines a unique aggressive prostate cancer phenotype.
Filon M, Gawdzik J, Truong A, Allen G, Huang W, Khemees T, Machhi R, Lewis P, Yang B, Denu J, Jarrard D
Br J Cancer 2021 Jul;125(2):247-254. Epub 2021 May 11 doi: 10.1038/s41416-021-01398-7. PMID: 33976366Free PMC Article
Benign mimics of prostate cancer.
Egevad L, Delahunt B, Furusato B, Tsuzuki T, Yaxley J, Samaratunga H
Pathology 2021 Jan;53(1):26-35. Epub 2020 Oct 16 doi: 10.1016/j.pathol.2020.08.006. PMID: 33070957
Dynamic patterns of [(68)Ga]Ga-PSMA-11 uptake in recurrent prostate cancer lesions.
Alberts I, Sachpekidis C, Gourni E, Boxler S, Gross T, Thalmann G, Rahbar K, Rominger A, Afshar-Oromieh A
Eur J Nucl Med Mol Imaging 2020 Jan;47(1):160-167. Epub 2019 Oct 18 doi: 10.1007/s00259-019-04545-8. PMID: 31628514
Pathophysiology and Contributing Factors in Postprostatectomy Incontinence: A Review.
Heesakkers J, Farag F, Bauer RM, Sandhu J, De Ridder D, Stenzl A
Eur Urol 2017 Jun;71(6):936-944. Epub 2016 Oct 6 doi: 10.1016/j.eururo.2016.09.031. PMID: 27720536
Prostate-specific antigen. Current role in diagnostic pathology of prostate cancer.
Bostwick DG
Am J Clin Pathol 1994 Oct;102(4 Suppl 1):S31-7. PMID: 7524305

Diagnosis

Tandem histone methyltransferase upregulation defines a unique aggressive prostate cancer phenotype.
Filon M, Gawdzik J, Truong A, Allen G, Huang W, Khemees T, Machhi R, Lewis P, Yang B, Denu J, Jarrard D
Br J Cancer 2021 Jul;125(2):247-254. Epub 2021 May 11 doi: 10.1038/s41416-021-01398-7. PMID: 33976366Free PMC Article
Benign mimics of prostate cancer.
Egevad L, Delahunt B, Furusato B, Tsuzuki T, Yaxley J, Samaratunga H
Pathology 2021 Jan;53(1):26-35. Epub 2020 Oct 16 doi: 10.1016/j.pathol.2020.08.006. PMID: 33070957
Giant multilocular prostatic cystadenoma.
Nakamura Y, Shida D, Shibayama T, Yoshida A, Matsui Y, Shinoda Y, Iwata S, Kanemitsu Y
World J Surg Oncol 2019 Feb 26;17(1):42. doi: 10.1186/s12957-019-1579-7. PMID: 30808350Free PMC Article
Mesenchymal tumors of the prostate.
McKenney JK
Mod Pathol 2018 Jan;31(S1):S133-142. doi: 10.1038/modpathol.2017.155. PMID: 29297486
GATA3 Is a Sensitive and Specific Marker of Benign and Malignant Mesonephric Lesions in the Lower Female Genital Tract.
Howitt BE, Emori MM, Drapkin R, Gaspar C, Barletta JA, Nucci MR, McCluggage WG, Oliva E, Hirsch MS
Am J Surg Pathol 2015 Oct;39(10):1411-9. doi: 10.1097/PAS.0000000000000471. PMID: 26135559

Therapy

Effectiveness and Safety of Prostatic Artery Embolization for the Treatment of Lower Urinary Tract Symptoms from Benign Prostatic Hyperplasia in Men with Concurrent Localized Prostate Cancer.
Parikh N, Keshishian E, Manley B, Grass GD, Torres-Roca J, Boulware D, Feuerlein S, Pow-Sang JM, Bagla S, Yamoah K, Bhatia S
J Vasc Interv Radiol 2021 Jul;32(7):1053-1061. Epub 2021 Mar 29 doi: 10.1016/j.jvir.2021.03.534. PMID: 33794373
Pathophysiology and Contributing Factors in Postprostatectomy Incontinence: A Review.
Heesakkers J, Farag F, Bauer RM, Sandhu J, De Ridder D, Stenzl A
Eur Urol 2017 Jun;71(6):936-944. Epub 2016 Oct 6 doi: 10.1016/j.eururo.2016.09.031. PMID: 27720536
5alpha-reductase activity in the prostate.
Steers WD
Urology 2001 Dec;58(6 Suppl 1):17-24; discussion 24. doi: 10.1016/s0090-4295(01)01299-7. PMID: 11750244
Loss of cyclin-dependent kinase inhibitor p27Kip1 is a novel prognostic factor in localized human prostate adenocarcinoma.
Tsihlias J, Kapusta LR, DeBoer G, Morava-Protzner I, Zbieranowski I, Bhattacharya N, Catzavelos GC, Klotz LH, Slingerland JM
Cancer Res 1998 Feb 1;58(3):542-8. PMID: 9458103
Definitive radiotherapy following prostatectomy: results and complications.
Forman JD, Wharam MD, Lee DJ, Zinreich ES, Order SE
Int J Radiat Oncol Biol Phys 1986 Feb;12(2):185-9. doi: 10.1016/0360-3016(86)90092-1. PMID: 3949568

Prognosis

Prostate extracellular vesicles in patient plasma as a liquid biopsy platform for prostate cancer using nanoscale flow cytometry.
Biggs CN, Siddiqui KM, Al-Zahrani AA, Pardhan S, Brett SI, Guo QQ, Yang J, Wolf P, Power NE, Durfee PN, MacMillan CD, Townson JL, Brinker JC, Fleshner NE, Izawa JI, Chambers AF, Chin JL, Leong HS
Oncotarget 2016 Feb 23;7(8):8839-49. doi: 10.18632/oncotarget.6983. PMID: 26814433Free PMC Article
GATA3 Is a Sensitive and Specific Marker of Benign and Malignant Mesonephric Lesions in the Lower Female Genital Tract.
Howitt BE, Emori MM, Drapkin R, Gaspar C, Barletta JA, Nucci MR, McCluggage WG, Oliva E, Hirsch MS
Am J Surg Pathol 2015 Oct;39(10):1411-9. doi: 10.1097/PAS.0000000000000471. PMID: 26135559
Serum prosaposin levels are increased in patients with advanced prostate cancer.
Koochekpour S, Hu S, Vellasco-Gonzalez C, Bernardo R, Azabdaftari G, Zhu G, Zhau HE, Chung LW, Vessella RL
Prostate 2012 Feb;72(3):253-69. Epub 2011 May 31 doi: 10.1002/pros.21427. PMID: 21630292Free PMC Article
Specific transcription factors prognostic for prostate cancer progression.
Aoyagi K, Shima I, Wang M, Hu Y, Garcia FU, Stearns ME
Clin Cancer Res 1998 Sep;4(9):2153-60. PMID: 9748134
Prostate-specific antigen. Current role in diagnostic pathology of prostate cancer.
Bostwick DG
Am J Clin Pathol 1994 Oct;102(4 Suppl 1):S31-7. PMID: 7524305

Clinical prediction guides

Dynamic patterns of [(68)Ga]Ga-PSMA-11 uptake in recurrent prostate cancer lesions.
Alberts I, Sachpekidis C, Gourni E, Boxler S, Gross T, Thalmann G, Rahbar K, Rominger A, Afshar-Oromieh A
Eur J Nucl Med Mol Imaging 2020 Jan;47(1):160-167. Epub 2019 Oct 18 doi: 10.1007/s00259-019-04545-8. PMID: 31628514
miR-503 suppresses tumor cell proliferation and metastasis by directly targeting RNF31 in prostate cancer.
Guo J, Liu X, Wang M
Biochem Biophys Res Commun 2015 Sep 4;464(4):1302-1308. Epub 2015 Jul 29 doi: 10.1016/j.bbrc.2015.07.127. PMID: 26231797
GATA3 Is a Sensitive and Specific Marker of Benign and Malignant Mesonephric Lesions in the Lower Female Genital Tract.
Howitt BE, Emori MM, Drapkin R, Gaspar C, Barletta JA, Nucci MR, McCluggage WG, Oliva E, Hirsch MS
Am J Surg Pathol 2015 Oct;39(10):1411-9. doi: 10.1097/PAS.0000000000000471. PMID: 26135559
Specific transcription factors prognostic for prostate cancer progression.
Aoyagi K, Shima I, Wang M, Hu Y, Garcia FU, Stearns ME
Clin Cancer Res 1998 Sep;4(9):2153-60. PMID: 9748134
Prostate-specific antigen. Current role in diagnostic pathology of prostate cancer.
Bostwick DG
Am J Clin Pathol 1994 Oct;102(4 Suppl 1):S31-7. PMID: 7524305

Recent systematic reviews

Diagnosis and Treatment of a Mixed Epithelial Stromal Tumor of the Seminal Vesicle: A Systematic Review.
Babar M, Matloubieh J, Macdonald E, Cheng J, Aboumohamed A, Watts K
Urology 2022 Sep;167:13-18. Epub 2022 Feb 26 doi: 10.1016/j.urology.2022.02.012. PMID: 35231450

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