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Bird-fanciers lung

MedGen UID:
586
•Concept ID:
C0005592
•
Disease or Syndrome
Synonyms: Bird fancier's lung; Bird-fanciers' lung; Pigeon-breeder lung disease
SNOMED CT: Bird-fanciers' lung (69339004); Bird breeders' lung (69339004); Bird fanciers' disease (69339004); Avian protein hypersensitivity (69339004); Bird breeders' disease (69339004); Bird-fancier's lung (69339004); BFL - Bird fanciers lung (69339004); Bird fanciers lung (69339004); Bird fanciers' lung (69339004); Pigeon fancier's lung (69339004); Pigeon-breeders's disease (69339004)
 
Monarch Initiative: MONDO:0005668
Orphanet: ORPHA99908

Definition

Pigeon-breeder's lung disease, also called bird fancier?s lung, is a hypersensitivity pneumonitis (see this term) induced by inhalation of bird derived-proteins. Presentation can be acute with chills, cough, fever, shortness of breath, chest tightness usually resolving within 24 h after cessation of antigen exposure, sub-acute with cough and dyspnea over several days to weeks, whereas chronic form results in breathlessness, coughing, lack of appetite and weight loss. [from ORDO]

Professional guidelines

PubMed

Acute Exacerbation and Proposed Criteria for Progressive Pulmonary Fibrosis in Patients with Fibrotic Hypersensitivity Pneumonitis and Idiopathic Pulmonary Fibrosis.
Okuda R, Takemura T, Misumi T, Nagasawa R, Iwasawa T, Baba T, Hagiwara E, Ogura T
Respiration 2023;102(9):803-812. Epub 2023 Aug 24 doi: 10.1159/000533312. PMID: 37619546
Screening and diagnosis of acute and chronic bird-related hypersensitivity pneumonitis by serum IgG and IgA antibodies to bird antigens with ImmunoCAP®.
Shirai T, Tanino Y, Nikaido T, Takaku Y, Hashimoto S, Taguchi Y, Baba T, Ogura T, Kataoka K, Nakayama M, Yamada Y, Matsushima S, Nakayama S, Miyazaki Y
Allergol Int 2021 Apr;70(2):208-214. Epub 2020 Oct 8 doi: 10.1016/j.alit.2020.09.003. PMID: 33041192
Non immunological analytic data for the differential diagnosis between miliary tuberculosis (MTBC) and bird breeder's disease (BBD).
Madrenas J, Curull V, Barbero L, Vidal R, Morell F
Allergol Immunopathol (Madr) 1985 Jul-Aug;13(4):301-4. PMID: 4083226

Recent clinical studies

Etiology

Database analysis of hypersensitivity pneumonitis in Japan.
Yamashita S, Okamoto T, Kawahara T, Tateishi T, Anzai T, Takahashi K, Fushimi K, Miyazaki Y
Respir Investig 2023 Mar;61(2):172-180. Epub 2023 Jan 23 doi: 10.1016/j.resinv.2022.12.003. PMID: 36696702
Diagnostic accuracy and safety of inhalation challenge tests for bird fancier's lung-Systematic review and meta-analysis.
Shiroshita A, Jin Z, Tanaka Y, Kataoka Y
Clin Exp Allergy 2020 Sep;50(9):1007-1016. Epub 2020 Jul 9 doi: 10.1111/cea.13685. PMID: 32557934
Bird fancier's lung: clinical-radiological presentation in 15 cases.
Kumar R, Singh M
Pneumonol Alergol Pol 2015;83(1):39-44. doi: 10.5603/PiAP.2015.0005. PMID: 25577532
Clinical features of recurrent and insidious chronic bird fancier's lung.
Ohtani Y, Saiki S, Sumi Y, Inase N, Miyake S, Costabel U, Yoshizawa Y
Ann Allergy Asthma Immunol 2003 Jun;90(6):604-10. doi: 10.1016/S1081-1206(10)61863-7. PMID: 12839317
Sleep in restrictive lung disease.
George CF, Kryger MH
Sleep 1987 Oct;10(5):409-18. doi: 10.1093/sleep/10.5.409. PMID: 3317724

Diagnosis

Database analysis of hypersensitivity pneumonitis in Japan.
Yamashita S, Okamoto T, Kawahara T, Tateishi T, Anzai T, Takahashi K, Fushimi K, Miyazaki Y
Respir Investig 2023 Mar;61(2):172-180. Epub 2023 Jan 23 doi: 10.1016/j.resinv.2022.12.003. PMID: 36696702
Bird fancier's lung serodiagnosis by automated r-IgLL1 ELISA.
Rouzet A, Scherer E, Barrera C, Gondouin A, Reboux G, Humbert K, Millon L, Bellanger AP
J Immunol Methods 2022 Jun;505:113267. Epub 2022 Apr 11 doi: 10.1016/j.jim.2022.113267. PMID: 35421363
Diagnostic accuracy and safety of inhalation challenge tests for bird fancier's lung-Systematic review and meta-analysis.
Shiroshita A, Jin Z, Tanaka Y, Kataoka Y
Clin Exp Allergy 2020 Sep;50(9):1007-1016. Epub 2020 Jul 9 doi: 10.1111/cea.13685. PMID: 32557934
Hypersensitivity pneumonitis: A new strategy for serodiagnosis and environmental surveys.
Bellanger AP, Reboux G, Rouzet A, Barrera C, Rocchi S, Scherer E, Millon L
Respir Med 2019 Apr;150:101-106. Epub 2019 Mar 5 doi: 10.1016/j.rmed.2019.02.019. PMID: 30961934
Bird Fancier's Lung.
Br Med J 1967 Jun 17;2(5554):713-4. PMID: 6026783Free PMC Article

Therapy

Rituximab therapy in a patient with steroid-refractory bird fancier's lung.
Ceci Bonello E, Gauci J, Bonello S, Fsadni P, Montefort S
BMJ Case Rep 2020 Dec 22;13(12) doi: 10.1136/bcr-2020-237232. PMID: 33370981Free PMC Article
Diagnostic accuracy and safety of inhalation challenge tests for bird fancier's lung-Systematic review and meta-analysis.
Shiroshita A, Jin Z, Tanaka Y, Kataoka Y
Clin Exp Allergy 2020 Sep;50(9):1007-1016. Epub 2020 Jul 9 doi: 10.1111/cea.13685. PMID: 32557934
Hypersensitivity pneumonitis: A new strategy for serodiagnosis and environmental surveys.
Bellanger AP, Reboux G, Rouzet A, Barrera C, Rocchi S, Scherer E, Millon L
Respir Med 2019 Apr;150:101-106. Epub 2019 Mar 5 doi: 10.1016/j.rmed.2019.02.019. PMID: 30961934
Exacerbation of Previously Undiagnosed Bird Fancier's Lung by Pembrolizumab Therapy.
Vu A, Vassallo R, Ryu JH
Chest 2019 Apr;155(4):e79-e82. doi: 10.1016/j.chest.2018.12.002. PMID: 30955583
Feather duvet lung.
Inase N, Ohtani Y, Endo J, Miyake S, Yoshizawa Y
Med Sci Monit 2003 May;9(5):CS37-40. PMID: 12761461

Prognosis

Diagnostic accuracy and safety of inhalation challenge tests for bird fancier's lung-Systematic review and meta-analysis.
Shiroshita A, Jin Z, Tanaka Y, Kataoka Y
Clin Exp Allergy 2020 Sep;50(9):1007-1016. Epub 2020 Jul 9 doi: 10.1111/cea.13685. PMID: 32557934
Hypersensitivity pneumonitis: A new strategy for serodiagnosis and environmental surveys.
Bellanger AP, Reboux G, Rouzet A, Barrera C, Rocchi S, Scherer E, Millon L
Respir Med 2019 Apr;150:101-106. Epub 2019 Mar 5 doi: 10.1016/j.rmed.2019.02.019. PMID: 30961934
Bird fancier's lung: a state-of-the-art review.
Chan AL, Juarez MM, Leslie KO, Ismail HA, Albertson TE
Clin Rev Allergy Immunol 2012 Aug;43(1-2):69-83. doi: 10.1007/s12016-011-8282-y. PMID: 21870048
Clinical features of recurrent and insidious chronic bird fancier's lung.
Ohtani Y, Saiki S, Sumi Y, Inase N, Miyake S, Costabel U, Yoshizawa Y
Ann Allergy Asthma Immunol 2003 Jun;90(6):604-10. doi: 10.1016/S1081-1206(10)61863-7. PMID: 12839317
Clinical and serologic follow-up of four children and five adults with bird-fancier's lung.
Grammer LC, Roberts M, Lerner C, Patterson R
J Allergy Clin Immunol 1990 Mar;85(3):655-60. doi: 10.1016/0091-6749(90)90107-f. PMID: 2107243

Clinical prediction guides

Diagnostic accuracy and safety of inhalation challenge tests for bird fancier's lung-Systematic review and meta-analysis.
Shiroshita A, Jin Z, Tanaka Y, Kataoka Y
Clin Exp Allergy 2020 Sep;50(9):1007-1016. Epub 2020 Jul 9 doi: 10.1111/cea.13685. PMID: 32557934
Hypersensitivity pneumonitis: A new strategy for serodiagnosis and environmental surveys.
Bellanger AP, Reboux G, Rouzet A, Barrera C, Rocchi S, Scherer E, Millon L
Respir Med 2019 Apr;150:101-106. Epub 2019 Mar 5 doi: 10.1016/j.rmed.2019.02.019. PMID: 30961934
Clinical features of recurrent and insidious chronic bird fancier's lung.
Ohtani Y, Saiki S, Sumi Y, Inase N, Miyake S, Costabel U, Yoshizawa Y
Ann Allergy Asthma Immunol 2003 Jun;90(6):604-10. doi: 10.1016/S1081-1206(10)61863-7. PMID: 12839317
Chronic hypersensitivity pneumonitis in Japan: a nationwide epidemiologic survey.
Yoshizawa Y, Ohtani Y, Hayakawa H, Sato A, Suga M, Ando M
J Allergy Clin Immunol 1999 Feb;103(2 Pt 1):315-20. doi: 10.1016/s0091-6749(99)70507-5. PMID: 9949324
Lung fibrosis in hypersensitivity pneumonitis. Association with CD4+ but not CD8+ cell dominant alveolitis and insidious onset.
Murayama J, Yoshizawa Y, Ohtsuka M, Hasegawa S
Chest 1993 Jul;104(1):38-43. doi: 10.1378/chest.104.1.38. PMID: 8325114

Recent systematic reviews

Diagnostic accuracy and safety of inhalation challenge tests for bird fancier's lung-Systematic review and meta-analysis.
Shiroshita A, Jin Z, Tanaka Y, Kataoka Y
Clin Exp Allergy 2020 Sep;50(9):1007-1016. Epub 2020 Jul 9 doi: 10.1111/cea.13685. PMID: 32557934

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