U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Parasystole

MedGen UID:
60067
•Concept ID:
C0206068
•
Pathologic Function
Synonym: Parasystoles
SNOMED CT: Parasystole (10164001); Parasystolic beat (10164001)

Definition

A cardiac arrhythmia that is caused by interaction of two independently initiated cardiac impulses of different rates from two separate foci. Generally one focus is the SINOATRIAL NODE, the normal pacemaker. The ectopic focus is usually in the HEART VENTRICLE but can be in the HEART ATRIUM or the ATRIOVENTRICULAR NODE. Modulation of the parasystolic rhythm by the sinus rhythm depends on the completeness of entrance block surrounding the parasystolic focus. [from MeSH]

Professional guidelines

PubMed

The diagnostic criteria for classic parasystole.
Ren Z, Zhou J, Xu G, Xian T, Xie L, Zhuang Y
Chin Med J (Engl) 1999 Nov;112(11):992-4. PMID: 11721482
Long-term ventricular pacing in treatment of sinoatrial block.
Bayley TJ
Br Med J 1971 Aug;3(5772):456-8. doi: 10.1136/bmj.3.5772.456. PMID: 5567769Free PMC Article

Recent clinical studies

Etiology

Ventricular Parasystole in Cardiomyopathy Patients: A Link Between His-Purkinje System Damage and Ventricular Fibrillation.
Do DH, O'Meara K, Lee J, Meyer S, Hanna P, Mori S, Fishbein MC, Boyle NG, Elizari MV, Bradfield JS, Shivkumar K
JACC Clin Electrophysiol 2023 Jul;9(7 Pt 1):936-948. Epub 2023 Feb 22 doi: 10.1016/j.jacep.2022.11.014. PMID: 37438043
Coupling interval variability of premature ventricular contractions in patients with different underlying pathology: an insight into the arrhythmia mechanism.
de Vries LJ, Martirosyan M, van Domburg RT, Wijchers SA, Géczy T, Szili-Torok T
J Interv Card Electrophysiol 2018 Jan;51(1):25-33. Epub 2018 Jan 5 doi: 10.1007/s10840-017-0309-8. PMID: 29305677Free PMC Article
Thalidomide causes sinus bradycardia in ALS.
Meyer T, Maier A, Borisow N, Dullinger JS, Splettstösser G, Ohlraun S, Münch C, Linke P
J Neurol 2008 Apr;255(4):587-91. Epub 2008 Apr 21 doi: 10.1007/s00415-008-0756-3. PMID: 18425621
The diagnostic criteria for classic parasystole.
Ren Z, Zhou J, Xu G, Xian T, Xie L, Zhuang Y
Chin Med J (Engl) 1999 Nov;112(11):992-4. PMID: 11721482
Electronic pacemaker models of parasystole. With special reference to artificial intermittent parasystole with phase 3 and phase 4 protection and to parasystolic modulation.
Castellanos A, Castillo CA, Medina-Ravell V, Moleiro F, Berkovits BV, Myerburg RJ
Pacing Clin Electrophysiol 1982 Jul;5(4):537-45. doi: 10.1111/j.1540-8159.1982.tb02275.x. PMID: 6180396

Diagnosis

Timed RR-interval Scatter Plots and Reverse Technology.
Xiang JT
Curr Med Sci 2020 Dec;40(6):1191-1202. Epub 2021 Jan 11 doi: 10.1007/s11596-020-2308-8. PMID: 33428149
New Heart…New Rhythm.
Yadlapati A, Kim SS, Knight BP
Pacing Clin Electrophysiol 2017 Jan;40(1):67-68. Epub 2016 Dec 22 doi: 10.1111/pace.12980. PMID: 27868219
Sinus parasystole.
Satullo G, Oreto G, Luzza F, Consolo A, Donato A
Am Heart J 1991 May;121(5):1507-12. doi: 10.1016/0002-8703(91)90159-f. PMID: 1708199
Parasystole.
Steffens TG, Gettes LS
Cardiovasc Clin 1974;6(1):99-110. PMID: 4611617
Parasystole.
Chung EK
Prog Cardiovasc Dis 1968 Jul;11(1):64-81. doi: 10.1016/s0033-0620(68)80012-x. PMID: 4172854

Therapy

Pseudo-Atrial Parasystoles After Open Heart Surgery and Catheter Ablation.
Nakamura K, Sasaki T, Minami K, Sasaki W, Kimura K, Take Y, Naito S
JACC Clin Electrophysiol 2021 Mar;7(3):431-432. doi: 10.1016/j.jacep.2020.12.022. PMID: 33736762
New Heart…New Rhythm.
Yadlapati A, Kim SS, Knight BP
Pacing Clin Electrophysiol 2017 Jan;40(1):67-68. Epub 2016 Dec 22 doi: 10.1111/pace.12980. PMID: 27868219
Thalidomide causes sinus bradycardia in ALS.
Meyer T, Maier A, Borisow N, Dullinger JS, Splettstösser G, Ohlraun S, Münch C, Linke P
J Neurol 2008 Apr;255(4):587-91. Epub 2008 Apr 21 doi: 10.1007/s00415-008-0756-3. PMID: 18425621
Clinical evaluation of excitability measures in sensory nerve.
Kiernan MC, Lin CS, Andersen KV, Murray NM, Bostock H
Muscle Nerve 2001 Jul;24(7):883-92. doi: 10.1002/mus.1085. PMID: 11410915
Parasystole.
Chung EK
Prog Cardiovasc Dis 1968 Jul;11(1):64-81. doi: 10.1016/s0033-0620(68)80012-x. PMID: 4172854

Prognosis

Ventricular Parasystole in Cardiomyopathy Patients: A Link Between His-Purkinje System Damage and Ventricular Fibrillation.
Do DH, O'Meara K, Lee J, Meyer S, Hanna P, Mori S, Fishbein MC, Boyle NG, Elizari MV, Bradfield JS, Shivkumar K
JACC Clin Electrophysiol 2023 Jul;9(7 Pt 1):936-948. Epub 2023 Feb 22 doi: 10.1016/j.jacep.2022.11.014. PMID: 37438043
Left ventricular outflow tract parasystole.
McIntyre WF, Baranchuk A
Arch Cardiovasc Dis 2011 May;104(5):359-60. Epub 2011 Mar 26 doi: 10.1016/j.acvd.2010.09.008. PMID: 21693373
Premature ventricular contractions originating from the left ventricular septum: results of radiofrequency catheter ablation in twenty patients.
Jia L, Yue-Chun L, Kang-Ting J, Na-Dan Z, Jia-Xuan L, Wen-Wu Z, Peng-Lin Y, Ji-Fei T, Jia-Feng L
BMC Cardiovasc Disord 2011 Jun 2;11:27. doi: 10.1186/1471-2261-11-27. PMID: 21635765Free PMC Article
Dynamics of pure parasystole.
Glass L, Goldberger AL, Bélair J
Am J Physiol 1986 Oct;251(4 Pt 2):H841-7. doi: 10.1152/ajpheart.1986.251.4.H841. PMID: 3766761
Parasystole.
Chung EK
Prog Cardiovasc Dis 1968 Jul;11(1):64-81. doi: 10.1016/s0033-0620(68)80012-x. PMID: 4172854

Clinical prediction guides

Timed RR-interval Scatter Plots and Reverse Technology.
Xiang JT
Curr Med Sci 2020 Dec;40(6):1191-1202. Epub 2021 Jan 11 doi: 10.1007/s11596-020-2308-8. PMID: 33428149
Premature ventricular contractions originating from the left ventricular septum: results of radiofrequency catheter ablation in twenty patients.
Jia L, Yue-Chun L, Kang-Ting J, Na-Dan Z, Jia-Xuan L, Wen-Wu Z, Peng-Lin Y, Ji-Fei T, Jia-Feng L
BMC Cardiovasc Disord 2011 Jun 2;11:27. doi: 10.1186/1471-2261-11-27. PMID: 21635765Free PMC Article
Dynamics of pure parasystole.
Glass L, Goldberger AL, Bélair J
Am J Physiol 1986 Oct;251(4 Pt 2):H841-7. doi: 10.1152/ajpheart.1986.251.4.H841. PMID: 3766761
Mechanism of supraventricular parasystole.
Kinoshita S, Nakagawa K, Kato N, Nishino T, Tanabe Y
Circulation 1982 Jan;65(1):208-12. doi: 10.1161/01.cir.65.1.208. PMID: 6171360
Mechanisms of ventricular parasystole.
Kinoshita S
Circulation 1978 Oct;58(4):715-22. doi: 10.1161/01.cir.58.4.715. PMID: 80290

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...