U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Anterior chamber cells

MedGen UID:
602221
Concept ID:
C0423282
Finding
SNOMED CT: Anterior chamber cells (246993000)
 
HPO: HP:0025560

Definition

Tiny deposits corresponding to cells floating in the anterior chamber of the eye. This appearance is typically associated with intraocular inflammation leading to breakdown of the blood-aqueous barrier and resulting in an increase in the number of cells and in the aqueous humor. Grading (SUN Working Group) is performed by estimating the number of cells in a 1 mm by 1 mm slit beam field, employing adequate light intensity and magnification on a slit lamp. [from HPO]

Professional guidelines

PubMed

Pichi F, Neri P, Aljneibi S, Hay S, Chaudhry H, Carreño E
Transl Vis Sci Technol 2024 May 1;13(5):15. doi: 10.1167/tvst.13.5.15. PMID: 38767904Free PMC Article
Takase H, Goto H, Namba K, Mizuki N, Okada AA, Ohguro N, Sonoda KH, Tomita M, Keino H, Kezuka T, Kubono R, Mizuuchi K, Shibuya E, Takahashi H, Yanai R, Mochizuki M; Japan ARN Study Group
Ocul Immunol Inflamm 2022 Jan 2;30(1):48-53. Epub 2020 Sep 18 doi: 10.1080/09273948.2020.1789179. PMID: 32945715
Ung L, Wang Y, Vangel M, Davies EC, Gardiner M, Bispo PJM, Gilmore MS, Chodosh J
Am J Ophthalmol 2020 Jun;214:97-109. Epub 2019 Dec 30 doi: 10.1016/j.ajo.2019.12.019. PMID: 31899203

Recent clinical studies

Etiology

Huard J, Mihailescu SD, Muraine M, Raymond S, Grall Lerosey M, Gueudry J
Ocul Immunol Inflamm 2023 Dec;31(10):2039-2049. Epub 2023 Dec 14 doi: 10.1080/09273948.2023.2279682. PMID: 37972236
Papaliodis GN, Rosner BA, Dreger KA, Fitzgerald TD, Artornsombudh P, Kothari S, Gangaputra SS, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT, Sen HN, Suhler EB, Thorne JE, Bhatt NP, Foster CS, Jabs DA, Pak CM, Ying GS, Kempen JH; Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort Study Research Group
Am J Ophthalmol 2023 Oct;254:221-232. Epub 2023 Jul 5 doi: 10.1016/j.ajo.2023.06.021. PMID: 37414328Free PMC Article
Mohanty A, Kelgaonkar A, Behera HS, Mallick A, Das S, Rekha Priyadarshini S, Chaurasia S, Sahu SK
Cornea 2023 Nov 1;42(11):1439-1445. Epub 2023 Jan 18 doi: 10.1097/ICO.0000000000003230. PMID: 36727968
Jacobovitz S, Massote JA, Cronemberger S
Eur J Ophthalmol 2019 May;29(3):278-286. Epub 2018 Nov 26 doi: 10.1177/1120672118815066. PMID: 30474392
Jabs DA, Nussenblatt RB, Rosenbaum JT; Standardization of Uveitis Nomenclature (SUN) Working Group
Am J Ophthalmol 2005 Sep;140(3):509-16. doi: 10.1016/j.ajo.2005.03.057. PMID: 16196117Free PMC Article

Diagnosis

Pichi F, Neri P
Int Ophthalmol 2024 Aug 9;44(1):344. doi: 10.1007/s10792-024-03273-9. PMID: 39122881
Verma L, Malik A, Maharana PK, Dada T, Sharma N
Indian J Ophthalmol 2024 Jan 1;72(1):11-18. Epub 2023 Dec 22 doi: 10.4103/IJO.IJO_1796_23. PMID: 38131565Free PMC Article
Mohanty A, Kelgaonkar A, Behera HS, Mallick A, Das S, Rekha Priyadarshini S, Chaurasia S, Sahu SK
Cornea 2023 Nov 1;42(11):1439-1445. Epub 2023 Jan 18 doi: 10.1097/ICO.0000000000003230. PMID: 36727968
Chan NS, Chee SP
Clin Exp Ophthalmol 2019 Apr;47(3):320-333. Epub 2018 Nov 13 doi: 10.1111/ceo.13417. PMID: 30345620
Jabs DA, Nussenblatt RB, Rosenbaum JT; Standardization of Uveitis Nomenclature (SUN) Working Group
Am J Ophthalmol 2005 Sep;140(3):509-16. doi: 10.1016/j.ajo.2005.03.057. PMID: 16196117Free PMC Article

Therapy

Huard J, Mihailescu SD, Muraine M, Raymond S, Grall Lerosey M, Gueudry J
Ocul Immunol Inflamm 2023 Dec;31(10):2039-2049. Epub 2023 Dec 14 doi: 10.1080/09273948.2023.2279682. PMID: 37972236
Mohanty A, Kelgaonkar A, Behera HS, Mallick A, Das S, Rekha Priyadarshini S, Chaurasia S, Sahu SK
Cornea 2023 Nov 1;42(11):1439-1445. Epub 2023 Jan 18 doi: 10.1097/ICO.0000000000003230. PMID: 36727968
Subudhi P, Patro S, Pattanayak S, Agarwal P, Sitaram S, Subudhi BNR
Indian J Ophthalmol 2022 May;70(5):1578-1581. doi: 10.4103/ijo.IJO_2509_21. PMID: 35502029Free PMC Article
Liu X, Solebo AL, Keane PA, Moore DJ, Denniston AK
Syst Rev 2019 Jan 22;8(1):30. doi: 10.1186/s13643-019-0946-3. PMID: 30670103Free PMC Article
Paul RH
Am J Ophthalmol 1988 May 15;105(5):519-22. doi: 10.1016/0002-9394(88)90244-9. PMID: 3285693

Prognosis

Verma L, Malik A, Maharana PK, Dada T, Sharma N
Indian J Ophthalmol 2024 Jan 1;72(1):11-18. Epub 2023 Dec 22 doi: 10.4103/IJO.IJO_1796_23. PMID: 38131565Free PMC Article
Papaliodis GN, Rosner BA, Dreger KA, Fitzgerald TD, Artornsombudh P, Kothari S, Gangaputra SS, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT, Sen HN, Suhler EB, Thorne JE, Bhatt NP, Foster CS, Jabs DA, Pak CM, Ying GS, Kempen JH; Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort Study Research Group
Am J Ophthalmol 2023 Oct;254:221-232. Epub 2023 Jul 5 doi: 10.1016/j.ajo.2023.06.021. PMID: 37414328Free PMC Article
Lim YJ, Byon I, Kim HW, Park SW, Kwon HJ, Kim E
Korean J Ophthalmol 2023 Aug;37(4):299-306. Epub 2023 Jul 3 doi: 10.3341/kjo.2023.0017. PMID: 37400085Free PMC Article
Invernizzi A, Marchi S, Aldigeri R, Mastrofilippo V, Viscogliosi F, Soldani A, Adani C, Garoli E, Viola F, Fontana L, McCluskey P, Cimino L
Ophthalmology 2017 Nov;124(11):1670-1677. Epub 2017 Jun 16 doi: 10.1016/j.ophtha.2017.05.013. PMID: 28625685
Jabs DA, Nussenblatt RB, Rosenbaum JT; Standardization of Uveitis Nomenclature (SUN) Working Group
Am J Ophthalmol 2005 Sep;140(3):509-16. doi: 10.1016/j.ajo.2005.03.057. PMID: 16196117Free PMC Article

Clinical prediction guides

Vukojević M, Vukojevic N, Vuković A, Rupčić B, Blažević M, Blažević A
Acta Dermatovenerol Croat 2023 Dec;31(4):229-231. PMID: 38651852
Sakallioğlu AK, Alacamli G, Sattarpanah S, Guclu H
Rom J Ophthalmol 2023 Jul-Sep;67(3):238-243. doi: 10.22336/rjo.2023.40. PMID: 37876515Free PMC Article
Huryn LA, Kozycki CT, Serpen JY, Zein WM, Ullah E, Iannaccone A, Williams LB, Sobrin L, Brooks BP, Sen HN, Hufnagel RB, Kastner DL, Kodati S
Ophthalmology 2023 Apr;130(4):423-432. Epub 2022 Nov 2 doi: 10.1016/j.ophtha.2022.10.026. PMID: 36332842Free PMC Article
Denniston AK, Keane PA, Srivastava SK
Invest Ophthalmol Vis Sci 2017 May 1;58(6):BIO131-BIO140. doi: 10.1167/iovs.17-21788. PMID: 28655060
Invernizzi A, Marchi S, Aldigeri R, Mastrofilippo V, Viscogliosi F, Soldani A, Adani C, Garoli E, Viola F, Fontana L, McCluskey P, Cimino L
Ophthalmology 2017 Nov;124(11):1670-1677. Epub 2017 Jun 16 doi: 10.1016/j.ophtha.2017.05.013. PMID: 28625685

Recent systematic reviews

Zhou T, Yang M, Zhang J, Zhang G, Kang L, Guan H
Medicine (Baltimore) 2024 Jun 7;103(23):e37584. doi: 10.1097/MD.0000000000037584. PMID: 38847669Free PMC Article
Chen YS, Hung HT, Guo SP, Chang HC
Expert Rev Clin Pharmacol 2021 Dec;14(12):1527-1534. Epub 2021 Sep 24 doi: 10.1080/17512433.2021.1981860. PMID: 34524035
Wong K, Lim CW, Malvankar-Mehta MS, Hutnik C
Can J Ophthalmol 2021 Aug;56(4):256-267. Epub 2021 Feb 3 doi: 10.1016/j.jcjo.2020.12.004. PMID: 33548176
Liu X, Solebo AL, Faes L, Beese S, Braithwaite T, Round ME, Panthagani J, Kale AU, McNally TW, Abdulla D, Keane PA, Moore DJ, Denniston AK
Ocul Immunol Inflamm 2020 Aug 17;28(6):898-907. Epub 2019 Aug 16 doi: 10.1080/09273948.2019.1640883. PMID: 31418609Free PMC Article
Henry CR, Becker MD, Yang Y, Davis JL
Am J Ophthalmol 2018 Jun;190:142-149. Epub 2018 Mar 28 doi: 10.1016/j.ajo.2018.03.031. PMID: 29601822

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...