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Vaginal discharge symptom

MedGen UID:
614475
•Concept ID:
C0438692
•
Sign or Symptom
Synonym: Vaginal Discharge
SNOMED CT: Vaginal discharge symptom (162156001)

Definition

Normal or abnormal secretions from the vagina. Mucus produced by the cervical glands is discharged from the vagina naturally, especially during the childbearing years. Causes of abnormal vaginal discharge include infectious agents (e.g., Neisseria gonorrhea, Chlamydia trachomatis, Trichomonas, and Candida albicans), the presence of foreign bodies, and cervical or vaginal cancer. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVaginal discharge symptom

Professional guidelines

PubMed

Diagnosis and management of uterine fibroids: current trends and future strategies.
Ahmad A, Kumar M, Bhoi NR, Badruddeen, Akhtar J, Khan MI, Ajmal M, Ahmad M
J Basic Clin Physiol Pharmacol 2023 May 1;34(3):291-310. Epub 2023 Mar 30 doi: 10.1515/jbcpp-2022-0219. PMID: 36989026
Cystitis and Pyelonephritis: Diagnosis, Treatment, and Prevention.
Kolman KB
Prim Care 2019 Jun;46(2):191-202. doi: 10.1016/j.pop.2019.01.001. PMID: 31030820
Vaginitis: Diagnosis and Treatment.
Paladine HL, Desai UA
Am Fam Physician 2018 Mar 1;97(5):321-329. PMID: 29671516

Recent clinical studies

Etiology

Infectious Vaginitis, Cervicitis, and Pelvic Inflammatory Disease.
Shroff S
Med Clin North Am 2023 Mar;107(2):299-315. Epub 2022 Dec 26 doi: 10.1016/j.mcna.2022.10.009. PMID: 36759099
Vaginitis: Diagnosis and Treatment.
Paladine HL, Desai UA
Am Fam Physician 2018 Mar 1;97(5):321-329. PMID: 29671516
Vaginal discharge--causes, diagnosis, and treatment.
Mitchell H
BMJ 2004 May 29;328(7451):1306-8. doi: 10.1136/bmj.328.7451.1306. PMID: 15166070Free PMC Article
Vaginal foreign bodies.
Stricker T, Navratil F, Sennhauser FH
J Paediatr Child Health 2004 Apr;40(4):205-7. doi: 10.1111/j.1440-1754.2004.00338.x. PMID: 15009550
Cytolytic vaginosis.
Cibley LJ, Cibley LJ
Am J Obstet Gynecol 1991 Oct;165(4 Pt 2):1245-9. doi: 10.1016/s0002-9378(12)90736-x. PMID: 1951582

Diagnosis

Infectious Vaginitis, Cervicitis, and Pelvic Inflammatory Disease.
Shroff S
Med Clin North Am 2023 Mar;107(2):299-315. Epub 2022 Dec 26 doi: 10.1016/j.mcna.2022.10.009. PMID: 36759099
Sexually Transmitted Infections.
Smith L, Angarone MP
Urol Clin North Am 2015 Nov;42(4):507-18. doi: 10.1016/j.ucl.2015.06.004. PMID: 26475947
Vaginitis.
Hainer BL, Gibson MV
Am Fam Physician 2011 Apr 1;83(7):807-15. PMID: 21524046
Does this woman have an acute uncomplicated urinary tract infection?
Bent S, Nallamothu BK, Simel DL, Fihn SD, Saint S
JAMA 2002 May 22-29;287(20):2701-10. doi: 10.1001/jama.287.20.2701. PMID: 12020306
Vaginal discharge.
Murtagh J
Aust Fam Physician 1991 Feb;20(2):207-8, 212-3. PMID: 2039404

Therapy

Impact of Lactobacillus crispatus-containing oral and vaginal probiotics on vaginal health: a randomised double-blind placebo controlled clinical trial.
Mändar R, Sõerunurk G, Štšepetova J, Smidt I, Rööp T, Kõljalg S, Saare M, Ausmees K, Le DD, Jaagura M, Piiskop S, Tamm H, Salumets A
Benef Microbes 2023 Apr 18;14(2):143-152. Epub 2023 Mar 1 doi: 10.3920/BM2022.0091. PMID: 36856121
Dysmenorrhea.
McKenna KA, Fogleman CD
Am Fam Physician 2021 Aug 1;104(2):164-170. PMID: 34383437
Vaginitis in Nonpregnant Patients: ACOG Practice Bulletin, Number 215.
Obstet Gynecol 2020 Jan;135(1):e1-e17. doi: 10.1097/AOG.0000000000003604. PMID: 31856123
Vaginitis: Diagnosis and Treatment.
Paladine HL, Desai UA
Am Fam Physician 2018 Mar 1;97(5):321-329. PMID: 29671516
Vaginal discharge.
Murtagh J
Aust Fam Physician 1991 Feb;20(2):207-8, 212-3. PMID: 2039404

Prognosis

Prepubertal and Adolescent Vulvovaginitis: What to Do When a Girl Reports Vaginal Discharge.
Lanis A, Talib HJ, Dodson N
Pediatr Ann 2020 Apr 1;49(4):e170-e175. doi: 10.3928/19382359-20200317-01. PMID: 32275761
Cystitis and Pyelonephritis: Diagnosis, Treatment, and Prevention.
Kolman KB
Prim Care 2019 Jun;46(2):191-202. doi: 10.1016/j.pop.2019.01.001. PMID: 31030820
Emphysematous vaginitis.
Lima-Silva J, Vieira-Baptista P, Cavaco-Gomes J, Maia T, Beires J
J Low Genit Tract Dis 2015 Apr;19(2):e43-4. doi: 10.1097/LGT.0000000000000092. PMID: 25551590
Vaginitis: diagnosis and management.
Quan M
Postgrad Med 2010 Nov;122(6):117-27. doi: 10.3810/pgm.2010.11.2229. PMID: 21084788
Recurrent bacterial vaginosis.
Hay PE
Dermatol Clin 1998 Oct;16(4):769-73, xii-xiii. doi: 10.1016/s0733-8635(05)70044-9. PMID: 9891678

Clinical prediction guides

Impact of Lactobacillus crispatus-containing oral and vaginal probiotics on vaginal health: a randomised double-blind placebo controlled clinical trial.
Mändar R, Sõerunurk G, Štšepetova J, Smidt I, Rööp T, Kõljalg S, Saare M, Ausmees K, Le DD, Jaagura M, Piiskop S, Tamm H, Salumets A
Benef Microbes 2023 Apr 18;14(2):143-152. Epub 2023 Mar 1 doi: 10.3920/BM2022.0091. PMID: 36856121
Cystitis and Pyelonephritis: Diagnosis, Treatment, and Prevention.
Kolman KB
Prim Care 2019 Jun;46(2):191-202. doi: 10.1016/j.pop.2019.01.001. PMID: 31030820
Evidence-based mixture containing Lactobacillus strains and lactoferrin to prevent recurrent bacterial vaginosis: a double blind, placebo controlled, randomised clinical trial.
Russo R, Karadja E, De Seta F
Benef Microbes 2019 Feb 8;10(1):19-26. Epub 2018 Dec 10 doi: 10.3920/BM2018.0075. PMID: 30525953
Diagnosis and treatment of urinary tract infections across age groups.
Chu CM, Lowder JL
Am J Obstet Gynecol 2018 Jul;219(1):40-51. Epub 2018 Jan 2 doi: 10.1016/j.ajog.2017.12.231. PMID: 29305250
Vaginal infection.
Eschenbach DA
Clin Obstet Gynecol 1983 Mar;26(1):186-202. doi: 10.1097/00003081-198303000-00023. PMID: 6340892

Recent systematic reviews

Systematic review and meta-analysis of maternal and fetal outcomes among pregnant women with bacterial vaginosis.
Kenfack-Zanguim J, Kenmoe S, Bowo-Ngandji A, Kenfack-Momo R, Thierry Ebogo-Belobo J, Kengne-Ndé C, Serge Mbaga D, Zeuko'o Menkem E, Lontuo Fogang R, Tchatchouang S, Laure Ndzie Ondigui J, Irma Kame-Ngasse G, Nina Magoudjou-Pekam J, Roussel Takuissu G, Nkie Esemu S, Nantcho Clavela N, Barriere Fodjo A, Ndip L, Bigoga J, Megnekou R, Esemu LF
Eur J Obstet Gynecol Reprod Biol 2023 Oct;289:9-18. Epub 2023 Aug 17 doi: 10.1016/j.ejogrb.2023.08.013. PMID: 37611538
Pessaries (mechanical devices) for managing pelvic organ prolapse in women.
Bugge C, Adams EJ, Gopinath D, Stewart F, Dembinsky M, Sobiesuo P, Kearney R
Cochrane Database Syst Rev 2020 Nov 18;11(11):CD004010. doi: 10.1002/14651858.CD004010.pub4. PMID: 33207004Free PMC Article
Vaginal and Laparoscopic hysterectomy as an outpatient procedure: A systematic review.
Dedden SJ, Geomini PMAJ, Huirne JAF, Bongers MY
Eur J Obstet Gynecol Reprod Biol 2017 Sep;216:212-223. Epub 2017 Jul 22 doi: 10.1016/j.ejogrb.2017.07.015. PMID: 28810192
The Performance of the Vaginal Discharge Syndromic Management in Treating Vaginal and Cervical Infection: A Systematic Review and Meta-Analysis.
Zemouri C, Wi TE, Kiarie J, Seuc A, Mogasale V, Latif A, Broutet N
PLoS One 2016;11(10):e0163365. Epub 2016 Oct 5 doi: 10.1371/journal.pone.0163365. PMID: 27706174Free PMC Article
Vaginal health in contraceptive vaginal ring users - A review.
Lete I, Cuesta MC, Marín JM, Guerra S
Eur J Contracept Reprod Health Care 2013 Aug;18(4):234-41. Epub 2013 Jun 24 doi: 10.3109/13625187.2013.801954. PMID: 23790132

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