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Meningoencephalitis

MedGen UID:
6301
Concept ID:
C0025309
Disease or Syndrome
Synonyms: Cerebromeningitides; Cerebromeningitis; Encephalomeningitides; Encephalomeningitis; Meningoencephalitides
SNOMED CT: Meningoencephalitis (7125002)
 
Monarch Initiative: MONDO:0005845

Definition

Inflammation of the meninges and brain, generally secondary to an infectious cause. Pathogens may be bacterial, viral, fungal, or protozoan. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Vairo F, Haider N, Kock R, Ntoumi F, Ippolito G, Zumla A
Infect Dis Clin North Am 2019 Dec;33(4):1003-1025. doi: 10.1016/j.idc.2019.08.006. PMID: 31668189
Lynch JP 3rd, Kajon AE
Semin Respir Crit Care Med 2016 Aug;37(4):586-602. Epub 2016 Aug 3 doi: 10.1055/s-0036-1584923. PMID: 27486739Free PMC Article
Grace E, Asbill S, Virga K
Antimicrob Agents Chemother 2015 Nov;59(11):6677-81. Epub 2015 Aug 10 doi: 10.1128/AAC.01293-15. PMID: 26259797Free PMC Article

Recent clinical studies

Etiology

Succar EF, Turner JH, Chandra RK
Int Forum Allergy Rhinol 2019 May;9(S1):S4-S8. doi: 10.1002/alr.22330. PMID: 31087631
Messacar K, Fischer M, Dominguez SR, Tyler KL, Abzug MJ
Infect Dis Clin North Am 2018 Mar;32(1):145-162. Epub 2017 Dec 8 doi: 10.1016/j.idc.2017.10.007. PMID: 29224854Free PMC Article
Fang B, McKeon A, Hinson SR, Kryzer TJ, Pittock SJ, Aksamit AJ, Lennon VA
JAMA Neurol 2016 Nov 1;73(11):1297-1307. doi: 10.1001/jamaneurol.2016.2549. PMID: 27618707
Kaiser R
Infect Dis Clin North Am 2008 Sep;22(3):561-75, x. doi: 10.1016/j.idc.2008.03.013. PMID: 18755391
Lanska DJ
Neurology 2002 Aug 13;59(3):327-34. doi: 10.1212/wnl.59.3.327. PMID: 12177364

Diagnosis

Thy M, de Montmollin E, Bouadma L, Timsit JF, Sonneville R
Curr Opin Crit Care 2023 Oct 1;29(5):415-422. Epub 2023 Aug 9 doi: 10.1097/MCC.0000000000001087. PMID: 37641514
Ramachandran PS, Wilson MR
Neurol Clin 2018 Nov;36(4):687-703. doi: 10.1016/j.ncl.2018.07.004. PMID: 30366549Free PMC Article
Chadwick DR
Br Med Bull 2005;75-76:1-14. Epub 2006 Feb 10 doi: 10.1093/bmb/ldh057. PMID: 16474042
Lanska DJ
Neurology 2002 Aug 13;59(3):327-34. doi: 10.1212/wnl.59.3.327. PMID: 12177364
Seidel J
Pediatr Clin North Am 1985 Aug;32(4):881-92. doi: 10.1016/s0031-3955(16)34860-x. PMID: 3895137

Therapy

Caffes N, Hendricks K, Bradley JS, Twenhafel NA, Simard JM
Clin Infect Dis 2022 Oct 17;75(Suppl 3):S451-S458. doi: 10.1093/cid/ciac521. PMID: 36251558Free PMC Article
Stott KE, Loyse A, Jarvis JN, Alufandika M, Harrison TS, Mwandumba HC, Day JN, Lalloo DG, Bicanic T, Perfect JR, Hope W
Lancet Infect Dis 2021 Sep;21(9):e259-e271. Epub 2021 Apr 16 doi: 10.1016/S1473-3099(20)30771-4. PMID: 33872594
Cheong TZ, Davies RP
Ophthalmic Plast Reconstr Surg 2019 Mar/Apr;35(2):e47-e49. doi: 10.1097/IOP.0000000000001324. PMID: 30730432
Tripathi N, Watt K, Benjamin DK Jr
Semin Perinatol 2012 Dec;36(6):416-23. doi: 10.1053/j.semperi.2012.06.003. PMID: 23177800Free PMC Article
Chadwick DR
Br Med Bull 2005;75-76:1-14. Epub 2006 Feb 10 doi: 10.1093/bmb/ldh057. PMID: 16474042

Prognosis

Rojo JU, Rajendran R, Salazar JH
Lab Med 2023 Sep 5;54(5):e124-e132. doi: 10.1093/labmed/lmac158. PMID: 36638160
Nascimento OJM, da Silva IRF
Curr Opin Neurol 2017 Oct;30(5):500-507. doi: 10.1097/WCO.0000000000000471. PMID: 28617719
Britton PN, Eastwood K, Paterson B, Durrheim DN, Dale RC, Cheng AC, Kenedi C, Brew BJ, Burrow J, Nagree Y, Leman P, Smith DW, Read K, Booy R, Jones CA; Australasian Society of Infectious Diseases (ASID); Australasian College of Emergency Medicine (ACEM); Australian and New Zealand Association of Neurologists (ANZAN); Public Health Association of Australia (PHAA)
Intern Med J 2015 May;45(5):563-76. doi: 10.1111/imj.12749. PMID: 25955462
Lanska DJ
Neurology 2002 Aug 13;59(3):327-34. doi: 10.1212/wnl.59.3.327. PMID: 12177364
Hadfield MG, Aydin F, Lippman HR, Sanders KM
Clin Neuropathol 1997 Mar-Apr;16(2):55-60. PMID: 9101104

Clinical prediction guides

Charlier C, Perrodeau É, Leclercq A, Cazenave B, Pilmis B, Henry B, Lopes A, Maury MM, Moura A, Goffinet F, Dieye HB, Thouvenot P, Ungeheuer MN, Tourdjman M, Goulet V, de Valk H, Lortholary O, Ravaud P, Lecuit M; MONALISA study group
Lancet Infect Dis 2017 May;17(5):510-519. Epub 2017 Jan 28 doi: 10.1016/S1473-3099(16)30521-7. PMID: 28139432
Guzmán-De-Villoria JA, Fernández-García P, Borrego-Ruiz PJ
Radiologia 2017 Jan-Feb;59(1):2-16. Epub 2016 Dec 21 doi: 10.1016/j.rx.2016.09.007. PMID: 28012729
Filigheddu MT, Górgolas M, Ramos JM
Med Clin (Barc) 2017 Feb 9;148(3):125-131. Epub 2016 Dec 16 doi: 10.1016/j.medcli.2016.10.038. PMID: 27993415
Fang B, McKeon A, Hinson SR, Kryzer TJ, Pittock SJ, Aksamit AJ, Lennon VA
JAMA Neurol 2016 Nov 1;73(11):1297-1307. doi: 10.1001/jamaneurol.2016.2549. PMID: 27618707
Opperdoes FR, De Jonckheere JF, Tielens AG
Int J Parasitol 2011 Aug 1;41(9):915-24. Epub 2011 Jun 16 doi: 10.1016/j.ijpara.2011.04.004. PMID: 21722646

Recent systematic reviews

Zhang M, Wang H, Tang J, He Y, Xiong T, Li W, Qu Y, Mu D
BMC Pediatr 2021 Mar 15;21(1):127. doi: 10.1186/s12887-021-02599-y. PMID: 33722228Free PMC Article
Velasco R, Villagrán M, Jové M, Simó M, Vilariño N, Alemany M, Palmero R, Martínez-Villacampa MM, Nadal E, Bruna J
JAMA Neurol 2021 Jul 1;78(7):864-873. doi: 10.1001/jamaneurol.2021.0249. PMID: 33720308
Córdova E, Maiolo E, Corti M, Orduña T
Neurol Res 2010 Apr;32(3):238-44. doi: 10.1179/016164110X12644252260637. PMID: 20406601
Demicheli V, Debalini MG, Rivetti A
Cochrane Database Syst Rev 2009 Jan 21;2009(1):CD000977. doi: 10.1002/14651858.CD000977.pub2. PMID: 19160184Free PMC Article
Rafailidis PI, Mourtzoukou EG, Varbobitis IC, Falagas ME
Virol J 2008 Mar 27;5:47. doi: 10.1186/1743-422X-5-47. PMID: 18371229Free PMC Article

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