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Eschar

MedGen UID:
636469
•Concept ID:
C0521172
•
Pathologic Function
Synonyms: Black eschar; Black spot; Tache noire
SNOMED CT: Eschar (87319000)
 
HPO: HP:6000793

Definition

A type of wound characterized by dry, black, hard necrotic tissue. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEschar

Professional guidelines

PubMed

Advancing burn wound treatment: exploring hydrogel as a transdermal drug delivery system.
Goh M, Du M, Peng WR, Saw PE, Chen Z
Drug Deliv 2024 Dec;31(1):2300945. Epub 2024 Feb 16 doi: 10.1080/10717544.2023.2300945. PMID: 38366562Free PMC Article
Eschar removal by bromelain based enzymatic debridement (Nexobrid®) in burns: European consensus guidelines update.
Hirche C, Kreken Almeland S, Dheansa B, Fuchs P, Governa M, Hoeksema H, Korzeniowski T, Lumenta DB, Marinescu S, Martinez-Mendez JR, Plock JA, Sander F, Ziegler B, Kneser U
Burns 2020 Jun;46(4):782-796. Epub 2020 Mar 30 doi: 10.1016/j.burns.2020.03.002. PMID: 32241591
Current treatment recommendations for topical burn therapy.
Monafo WW, West MA
Drugs 1990 Sep;40(3):364-73. doi: 10.2165/00003495-199040030-00004. PMID: 2226220

Recent clinical studies

Etiology

Pediatric Burn Infection.
Williams FN, Lee JO
Surg Infect (Larchmt) 2021 Feb;22(1):54-57. Epub 2020 Aug 13 doi: 10.1089/sur.2020.218. PMID: 32790497
The Rickettsioses: A Practical Update.
Blanton LS
Infect Dis Clin North Am 2019 Mar;33(1):213-229. doi: 10.1016/j.idc.2018.10.010. PMID: 30712763Free PMC Article
Cutaneous mucormycosis.
Skiada A, Petrikkos G
Skinmed 2013 May-Jun;11(3):155-9; quiz 159-60. PMID: 23930354
Burn wound infections.
Church D, Elsayed S, Reid O, Winston B, Lindsay R
Clin Microbiol Rev 2006 Apr;19(2):403-34. doi: 10.1128/CMR.19.2.403-434.2006. PMID: 16614255Free PMC Article
Rickettsialpox.
Boyd AS
Dermatol Clin 1997 Apr;15(2):313-8. doi: 10.1016/s0733-8635(05)70439-3. PMID: 9098640

Diagnosis

The Rickettsioses: A Practical Update.
Blanton LS
Infect Dis Clin North Am 2019 Mar;33(1):213-229. doi: 10.1016/j.idc.2018.10.010. PMID: 30712763Free PMC Article
Rickettsial meningitis.
Salva I, de Sousa R, Gouveia C
BMJ Case Rep 2014 Mar 10;2014 doi: 10.1136/bcr-2013-203283. PMID: 24614778Free PMC Article
Cutaneous mucormycosis.
Skiada A, Petrikkos G
Skinmed 2013 May-Jun;11(3):155-9; quiz 159-60. PMID: 23930354
Burn wound infections.
Church D, Elsayed S, Reid O, Winston B, Lindsay R
Clin Microbiol Rev 2006 Apr;19(2):403-34. doi: 10.1128/CMR.19.2.403-434.2006. PMID: 16614255Free PMC Article
Rickettsialpox.
Boyd AS
Dermatol Clin 1997 Apr;15(2):313-8. doi: 10.1016/s0733-8635(05)70439-3. PMID: 9098640

Therapy

Eschar removal by bromelain based enzymatic debridement (Nexobrid®) in burns: European consensus guidelines update.
Hirche C, Kreken Almeland S, Dheansa B, Fuchs P, Governa M, Hoeksema H, Korzeniowski T, Lumenta DB, Marinescu S, Martinez-Mendez JR, Plock JA, Sander F, Ziegler B, Kneser U
Burns 2020 Jun;46(4):782-796. Epub 2020 Mar 30 doi: 10.1016/j.burns.2020.03.002. PMID: 32241591
The Rickettsioses: A Practical Update.
Blanton LS
Infect Dis Clin North Am 2019 Mar;33(1):213-229. doi: 10.1016/j.idc.2018.10.010. PMID: 30712763Free PMC Article
Rickettsial meningitis.
Salva I, de Sousa R, Gouveia C
BMJ Case Rep 2014 Mar 10;2014 doi: 10.1136/bcr-2013-203283. PMID: 24614778Free PMC Article
Burn wound infections.
Church D, Elsayed S, Reid O, Winston B, Lindsay R
Clin Microbiol Rev 2006 Apr;19(2):403-34. doi: 10.1128/CMR.19.2.403-434.2006. PMID: 16614255Free PMC Article
Rickettsialpox.
Boyd AS
Dermatol Clin 1997 Apr;15(2):313-8. doi: 10.1016/s0733-8635(05)70439-3. PMID: 9098640

Prognosis

Surgical Escharotomy and Decompressive Therapies in Burns.
Butts CC, Holmes JH, Carter JE
J Burn Care Res 2020 Feb 19;41(2):263-269. doi: 10.1093/jbcr/irz152. PMID: 31504609
Frostbite: prevention and initial management.
Zafren K
High Alt Med Biol 2013 Mar;14(1):9-12. doi: 10.1089/ham.2012.1114. PMID: 23537254
Calciphylaxis--a topical overview.
Arseculeratne G, Evans AT, Morley SM
J Eur Acad Dermatol Venereol 2006 May;20(5):493-502. doi: 10.1111/j.1468-3083.2006.01506.x. PMID: 16684274
Anthrax--an overview.
Oncü S, Oncü S, Sakarya S
Med Sci Monit 2003 Nov;9(11):RA276-83. PMID: 14586293
Rickettsialpox.
Boyd AS
Dermatol Clin 1997 Apr;15(2):313-8. doi: 10.1016/s0733-8635(05)70439-3. PMID: 9098640

Clinical prediction guides

The Tick-Borne Pathogens: An Overview of China's Situation.
Luan Y, Gou J, Zhong D, Ma L, Yin C, Shu M, Liu G, Lin Q
Acta Parasitol 2023 Mar;68(1):1-20. Epub 2023 Jan 16 doi: 10.1007/s11686-023-00658-1. PMID: 36642777Free PMC Article
Surgical Escharotomy and Decompressive Therapies in Burns.
Butts CC, Holmes JH, Carter JE
J Burn Care Res 2020 Feb 19;41(2):263-269. doi: 10.1093/jbcr/irz152. PMID: 31504609
Clinical and paraclinical profile, and predictors of outcome in 90 cases of scrub typhus, Meghalaya, India.
Sivarajan S, Shivalli S, Bhuyan D, Mawlong M, Barman R
Infect Dis Poverty 2016 Oct 5;5(1):91. doi: 10.1186/s40249-016-0186-x. PMID: 27716337Free PMC Article
Surgical interventions for high-grade vulval intraepithelial neoplasia.
Kaushik S, Pepas L, Nordin A, Bryant A, Dickinson HO
Cochrane Database Syst Rev 2014 Mar 4;2014(3):CD007928. doi: 10.1002/14651858.CD007928.pub3. PMID: 24596022Free PMC Article
Frostbite: prevention and initial management.
Zafren K
High Alt Med Biol 2013 Mar;14(1):9-12. doi: 10.1089/ham.2012.1114. PMID: 23537254

Recent systematic reviews

Clinical, epidemiological, and laboratory features of Rickettsia parkeri rickettsiosis: A systematic review.
Silva-Ramos CR, Hidalgo M, Faccini-Martínez ÁA
Ticks Tick Borne Dis 2021 Jul;12(4):101734. Epub 2021 May 1 doi: 10.1016/j.ttbdis.2021.101734. PMID: 33989945
Clinical manifestations of scrub typhus.
Rajapakse S, Weeratunga P, Sivayoganathan S, Fernando SD
Trans R Soc Trop Med Hyg 2017 Feb 1;111(2):43-54. doi: 10.1093/trstmh/trx017. PMID: 28449088
A Systematic Review of Mortality from Untreated Scrub Typhus (Orientia tsutsugamushi).
Taylor AJ, Paris DH, Newton PN
PLoS Negl Trop Dis 2015;9(8):e0003971. Epub 2015 Aug 14 doi: 10.1371/journal.pntd.0003971. PMID: 26274584Free PMC Article
Surgical interventions for high-grade vulval intraepithelial neoplasia.
Kaushik S, Pepas L, Nordin A, Bryant A, Dickinson HO
Cochrane Database Syst Rev 2014 Mar 4;2014(3):CD007928. doi: 10.1002/14651858.CD007928.pub3. PMID: 24596022Free PMC Article
Enzymatic wound debridement.
Ramundo J, Gray M
J Wound Ostomy Continence Nurs 2008 May-Jun;35(3):273-80. doi: 10.1097/01.WON.0000319125.21854.78. PMID: 18496083

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