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Foreign body granuloma

MedGen UID:
6672
•Concept ID:
C0018193
•
Pathologic Function
Synonyms: Foreign Body Granuloma; Foreign-Body Granuloma; Foreign-Body Granulomas; Granuloma, Foreign Body; Granuloma, Foreign-Body; Granulomas, Foreign-Body
SNOMED CT: Foreign body granuloma (37058002)

Definition

An inflammatory lesion comprised of epithelioid histiocytes and chronic inflammation that is caused by the presence of extraneous material. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVForeign body granuloma

Professional guidelines

PubMed

Orbital Approaches for Treatment of Carotid Cavernous Fistulas: A Systematic Review.
Phan K, Xu J, Leung V, Teng I, Sheik-Ali S, Maharaj M, Mobbs R, Rao PJ
World Neurosurg 2016 Dec;96:243-251. Epub 2016 Aug 29 doi: 10.1016/j.wneu.2016.08.087. PMID: 27586179
Amalgam tattoo (amalgam pigmentation) of the oral mucosa: clinical manifestations, diagnosis and treatment.
Buchner A
Refuat Hapeh Vehashinayim (1993) 2004 Jul;21(3):25-8, 92. PMID: 15503979
Amalgam tattoo (amalgam pigmentation) of the oral mucosa: clinical manifestations, diagnosis and treatment.
Buchner A
Refuat Hapeh Vehashinayim (1993) 2004 Apr;21(2):19-22, 96. PMID: 15503543

Recent clinical studies

Etiology

Conjunctival Foreign Body Granuloma after Pterygium Excision and Adaptation by Polyglactin Sutures.
Gerding H, Lipke K, Raak P, Brabeck C, Schlageter M, Tappeiner C, Goldblum D
Klin Monbl Augenheilkd 2023 Apr;240(4):391-393. Epub 2023 Apr 25 doi: 10.1055/a-2004-5330. PMID: 37164416
Adverse reactions to the injection of face and neck aesthetic filling materials: a systematic review.
Machado RA, Oliveira LQ, Martelli-Júnior H, Pires FR, Carvas JB, Rogerio VE, Rabelo VD, Coletta RD
Med Oral Patol Oral Cir Bucal 2023 May 1;28(3):e278-e284. doi: 10.4317/medoral.25713. PMID: 36565218Free PMC Article
Intracranial Foreign Body Granuloma Mimicking Brain Tumor Recurrence: A Case Series.
Winter SF, Forst DA, Oakley DH, Batchelor TT, Dietrich J
Oncologist 2021 May;26(5):e893-e897. Epub 2021 Apr 11 doi: 10.1002/onco.13766. PMID: 33780077Free PMC Article
The case of the eyelid silicone granulomas.
Wulu JA, Garcia-Rodriguez L, Prilutskiy A, Spiegel JH
Am J Otolaryngol 2019 Sep-Oct;40(5):776-778. Epub 2019 May 14 doi: 10.1016/j.amjoto.2019.05.010. PMID: 31133360
The gouty tophus: a review.
Chhana A, Dalbeth N
Curr Rheumatol Rep 2015 Mar;17(3):19. doi: 10.1007/s11926-014-0492-x. PMID: 25761926

Diagnosis

Adverse reactions to the injection of face and neck aesthetic filling materials: a systematic review.
Machado RA, Oliveira LQ, Martelli-Júnior H, Pires FR, Carvas JB, Rogerio VE, Rabelo VD, Coletta RD
Med Oral Patol Oral Cir Bucal 2023 May 1;28(3):e278-e284. doi: 10.4317/medoral.25713. PMID: 36565218Free PMC Article
Intracranial Foreign Body Granuloma Mimicking Brain Tumor Recurrence: A Case Series.
Winter SF, Forst DA, Oakley DH, Batchelor TT, Dietrich J
Oncologist 2021 May;26(5):e893-e897. Epub 2021 Apr 11 doi: 10.1002/onco.13766. PMID: 33780077Free PMC Article
Foreign body granuloma from a gunshot injury to the breast.
Chung HL, Leung JWT
Clin Imaging 2020 Dec;68:197-201. Epub 2020 Aug 27 doi: 10.1016/j.clinimag.2020.08.021. PMID: 32892104
Gossypiboma: a ghastly find.
de Gea Rico A, Krishna P, Devlin HL, Rohatgi A
BMJ Case Rep 2018 Sep 26;2018 doi: 10.1136/bcr-2017-221537. PMID: 30257871Free PMC Article
Occupational dermatosis.
Alchorne Ade O, Alchorne MM, Silva MM
An Bras Dermatol 2010 Mar-Apr;85(2):137-45; quiz 146-7. doi: 10.1590/s0365-05962010000200003. PMID: 20520928

Therapy

Imaging Features and Complications of Facial Cosmetic Procedures.
de Sousa AMS, Duarte AC, Decnop M, Guimarães DF, Coelho Neto CAF, Sarpi MO, Duarte LGP, Souza SA, Segato LF, Zavariz JD, Mukherji SK, Garcia MRT
Radiographics 2023 Dec;43(12):e230060. doi: 10.1148/rg.230060. PMID: 37943699
Adverse reactions to the injection of face and neck aesthetic filling materials: a systematic review.
Machado RA, Oliveira LQ, Martelli-Júnior H, Pires FR, Carvas JB, Rogerio VE, Rabelo VD, Coletta RD
Med Oral Patol Oral Cir Bucal 2023 May 1;28(3):e278-e284. doi: 10.4317/medoral.25713. PMID: 36565218Free PMC Article
The case of the eyelid silicone granulomas.
Wulu JA, Garcia-Rodriguez L, Prilutskiy A, Spiegel JH
Am J Otolaryngol 2019 Sep-Oct;40(5):776-778. Epub 2019 May 14 doi: 10.1016/j.amjoto.2019.05.010. PMID: 31133360
Foreign Body Granuloma After Cranial Surgery: A Systematic Review of Reported Cases.
Akhaddar A, Turgut AT, Turgut M
World Neurosurg 2018 Dec;120:457-475. Epub 2018 Sep 27 doi: 10.1016/j.wneu.2018.09.143. PMID: 30267951
The gouty tophus: a review.
Chhana A, Dalbeth N
Curr Rheumatol Rep 2015 Mar;17(3):19. doi: 10.1007/s11926-014-0492-x. PMID: 25761926

Prognosis

Foreign Body Granuloma Originating From the Lateral Process of Malleus: A Case Series of 19 Children.
Mao Y, Li L, Yan W, Lu Y, Li W, Zheng J, Fan Z, Wang H, Han Y
Otol Neurotol 2023 Aug 1;44(7):702-708. Epub 2023 Jun 12 doi: 10.1097/MAO.0000000000003918. PMID: 37311639Free PMC Article
Conjunctival Foreign Body Granuloma after Pterygium Excision and Adaptation by Polyglactin Sutures.
Gerding H, Lipke K, Raak P, Brabeck C, Schlageter M, Tappeiner C, Goldblum D
Klin Monbl Augenheilkd 2023 Apr;240(4):391-393. Epub 2023 Apr 25 doi: 10.1055/a-2004-5330. PMID: 37164416
Clinical and histopathological features of conjunctival "Teddy bear" granuloma: A case series.
Lozano-Bustillo A, Ríos Y Valles-Valles D, Hernández-Ayuso I, Rodríguez-Reyes AA
Eur J Ophthalmol 2022 Nov;32(6):3674-3678. Epub 2022 Mar 1 doi: 10.1177/11206721221083135. PMID: 35230194
The case of the eyelid silicone granulomas.
Wulu JA, Garcia-Rodriguez L, Prilutskiy A, Spiegel JH
Am J Otolaryngol 2019 Sep-Oct;40(5):776-778. Epub 2019 May 14 doi: 10.1016/j.amjoto.2019.05.010. PMID: 31133360
Foreign-body granuloma of the penis in sexually active individuals (penile paraffinoma).
Pehlivanov G, Kavaklieva S, Kazandjieva J, Kapnilov D, Tsankov N
J Eur Acad Dermatol Venereol 2008 Jul;22(7):845-51. Epub 2008 Mar 19 doi: 10.1111/j.1468-3083.2008.02677.x. PMID: 18355202

Clinical prediction guides

Morphological features of pilonidal cysts of the sacrococcygeal region.
Feleshtynskyi Y, Balan I, Dyadyk O, Beketova J
Pol Przegl Chir 2021 Jun 21;94(1):20-27. doi: 10.5604/01.3001.0015.7694. PMID: 35195080
A peritoneal defect covered by intraperitoneal mesh prosthesis effects an increased and distinctive foreign body reaction in a minipig model.
Eickhoff RM, Kroh A, Eickhoff S, Heise D, Helmedag MJ, Tolba RH, Klinge U, Neumann UP, Klink CD, Lambertz A
J Biomater Appl 2021 Jan;35(6):732-739. Epub 2020 Oct 8 doi: 10.1177/0885328220963918. PMID: 33331198
Activation of Herpes Simplex Infection after Tattoo.
Begolli Gerqari A, Ferizi M, Kotori M, Daka A, Hapciu S, Begolli I, Begolli M, Gerqari I
Acta Dermatovenerol Croat 2018 Apr;26(1):75-76. PMID: 29782308
Metastatic and prognostic factors in patients with alveolar echinococcosis.
Wang H, Lu C, Liu X, Zhang W
Int J Clin Exp Pathol 2015;8(9):11192-8. Epub 2015 Sep 1 PMID: 26617841Free PMC Article
Mechanisms of granulomatous inflammation.
Epstein WL, Fukuyama K
Immunol Ser 1989;46:687-721. PMID: 2488875

Recent systematic reviews

Cyanoacrylate glue reactions: A systematic review, cases, and proposed mechanisms.
Athavale A, Thao M, Sassaki VS, Lewis M, Chandra V, Fukaya E
J Vasc Surg Venous Lymphat Disord 2023 Jul;11(4):876-888.e1. Epub 2023 Apr 11 doi: 10.1016/j.jvsv.2023.03.018. PMID: 37054883
Adverse reactions to the injection of face and neck aesthetic filling materials: a systematic review.
Machado RA, Oliveira LQ, Martelli-Júnior H, Pires FR, Carvas JB, Rogerio VE, Rabelo VD, Coletta RD
Med Oral Patol Oral Cir Bucal 2023 May 1;28(3):e278-e284. doi: 10.4317/medoral.25713. PMID: 36565218Free PMC Article
Spilled gallstones after laparoscopic cholecystectomy: a systematic review.
Salati SA, Alfehaid M, Alsuwaydani S, AlSulaim L
Pol Przegl Chir 2022 May 24;95(2):1-20. doi: 10.5604/01.3001.0015.8571. PMID: 36805307
Foreign Body Granuloma After Cranial Surgery: A Systematic Review of Reported Cases.
Akhaddar A, Turgut AT, Turgut M
World Neurosurg 2018 Dec;120:457-475. Epub 2018 Sep 27 doi: 10.1016/j.wneu.2018.09.143. PMID: 30267951
Intracranial foreign material granulomas after cranial surgery.
Al-Afif S, Hatipoglu Majernik G, Hermann EJ, Esmaeilzadeh M, Hartmann C, Krauss JK
Acta Neurochir (Wien) 2018 Nov;160(11):2069-2075. Epub 2018 Sep 6 doi: 10.1007/s00701-018-3663-0. PMID: 30187219

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