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Granuloma, Respiratory Tract

MedGen UID:
6675
•Concept ID:
C0018200
•
Disease or Syndrome
Synonyms: Granuloma, Respiratory System; Respiratory System Granuloma; Respiratory System Granulomas; Respiratory Tract Granuloma; Respiratory Tract Granulomas

Definition

Granulomatous disorders affecting one or more sites in the respiratory tract. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGranuloma, Respiratory Tract

Professional guidelines

PubMed

Diagnosis and Treatment of Benign Pediatric Lesions.
Hron TA, Kavanagh KR, Murray N
Otolaryngol Clin North Am 2019 Aug;52(4):657-668. Epub 2019 May 11 doi: 10.1016/j.otc.2019.03.010. PMID: 31088693
Updated Medical and Surgical Treatment for Common Benign Laryngeal Lesions.
Kraimer KL, Husain I
Otolaryngol Clin North Am 2019 Aug;52(4):745-757. Epub 2019 May 8 doi: 10.1016/j.otc.2019.03.017. PMID: 31078305
Zinc sulfate treatment of vocal process granuloma.
Yilmaz T
Eur Arch Otorhinolaryngol 2013 Mar;270(3):1175. Epub 2012 Sep 30 doi: 10.1007/s00405-012-2196-z. PMID: 23053378

Recent clinical studies

Etiology

The End of the Binary Era: Revisiting the Spectrum of Tuberculosis.
Lin PL, Flynn JL
J Immunol 2018 Nov 1;201(9):2541-2548. doi: 10.4049/jimmunol.1800993. PMID: 30348659Free PMC Article
Histological Diagnoses of Military Personnel Undergoing Lung Biopsy After Deployment to Southwest Asia.
Madar CS, Lewin-Smith MR, Franks TJ, Harley RA, Klaric JS, Morris MJ
Lung 2017 Aug;195(4):507-515. Epub 2017 May 23 doi: 10.1007/s00408-017-0009-2. PMID: 28536739
Transplant Pulmonary Interventions: Translating Lung Transplant Interventions to Nontransplant Patients.
Sinha N
Methodist Debakey Cardiovasc J 2016 Oct-Dec;12(4 Suppl):18-20. doi: 10.14797/mdcj-12-4s1-18. PMID: 28298961Free PMC Article
Genetics of sarcoidosis.
Iannuzzi MC
Semin Respir Crit Care Med 2007 Feb;28(1):15-21. doi: 10.1055/s-2007-970330. PMID: 17330189
Pulmonary sarcoidosis: new genetic clues and ongoing treatment controversies.
Culver DA, Thomassen MJ, Kavuru MS
Cleve Clin J Med 2004 Feb;71(2):88, 90, 92 passim. doi: 10.3949/ccjm.71.2.88. PMID: 14982192

Diagnosis

Pulmonary Hyalinizing Granuloma.
Karakurt G, Duger M
Arch Bronconeumol 2022 Dec;58(12):821-822. Epub 2022 Jul 21 doi: 10.1016/j.arbres.2022.07.009. PMID: 35914957
"To do or not to do - that is the question". Transvascular needle aspiration during EBUS (EBUS-TVNA) with review of the literature.
Perathur AM, Joseph T, Nair SR, Varma U
Adv Respir Med 2021;89(4):386-391. doi: 10.5603/ARM.a2021.0074. PMID: 34494242
Pulmonary sarcoidosis.
Lynch JP 3rd, Ma YL, Koss MN, White ES
Semin Respir Crit Care Med 2007 Feb;28(1):53-74. doi: 10.1055/s-2007-970333. PMID: 17330192
Pathological diagnosis of granulomatous lung disease: a review.
El-Zammar OA, Katzenstein AL
Histopathology 2007 Feb;50(3):289-310. doi: 10.1111/j.1365-2559.2006.02546.x. PMID: 17257125
Interferon-induced granulomatous lung disease.
Marzouk K, Saleh S, Kannass M, Sharma OP
Curr Opin Pulm Med 2004 Sep;10(5):435-40. doi: 10.1097/01.mcp.0000134400.88832.9c. PMID: 15316444

Therapy

Transplant Pulmonary Interventions: Translating Lung Transplant Interventions to Nontransplant Patients.
Sinha N
Methodist Debakey Cardiovasc J 2016 Oct-Dec;12(4 Suppl):18-20. doi: 10.14797/mdcj-12-4s1-18. PMID: 28298961Free PMC Article
Granuloma-forming interstitial pneumonia occurring one year after the start of everolimus therapy.
Saito Y, Kunugi S, Suzuki Y, Narita K, Miura Y, Minegishi Y, Kimura G, Kondo Y, Azuma A, Fukuda Y, Gemma A
Intern Med 2013;52(2):263-7. Epub 2013 Jan 15 doi: 10.2169/internalmedicine.52.8588. PMID: 23318860
Pulmonary affectation of vasculitis.
Martín-Suñé N, Ríos-Blanco JJ
Arch Bronconeumol 2012 Nov;48(11):410-8. Epub 2012 Jun 6 doi: 10.1016/j.arbres.2012.04.007. PMID: 22682604
Pulmonary sarcoidosis.
Lynch JP 3rd, Ma YL, Koss MN, White ES
Semin Respir Crit Care Med 2007 Feb;28(1):53-74. doi: 10.1055/s-2007-970333. PMID: 17330192
Interferon-induced granulomatous lung disease.
Marzouk K, Saleh S, Kannass M, Sharma OP
Curr Opin Pulm Med 2004 Sep;10(5):435-40. doi: 10.1097/01.mcp.0000134400.88832.9c. PMID: 15316444

Prognosis

Immunological roulette: Luck or something more? Considering the connections between host and environment in TB.
Pearl JE, Das M, Cooper AM
Cell Mol Immunol 2018 Mar;15(3):226-232. Epub 2018 Jan 29 doi: 10.1038/cmi.2017.145. PMID: 29375129Free PMC Article
Histological Diagnoses of Military Personnel Undergoing Lung Biopsy After Deployment to Southwest Asia.
Madar CS, Lewin-Smith MR, Franks TJ, Harley RA, Klaric JS, Morris MJ
Lung 2017 Aug;195(4):507-515. Epub 2017 May 23 doi: 10.1007/s00408-017-0009-2. PMID: 28536739
Pulmonary sarcoidosis.
Lynch JP 3rd, Ma YL, Koss MN, White ES
Semin Respir Crit Care Med 2007 Feb;28(1):53-74. doi: 10.1055/s-2007-970333. PMID: 17330192
Genetics of sarcoidosis.
Iannuzzi MC
Semin Respir Crit Care Med 2007 Feb;28(1):15-21. doi: 10.1055/s-2007-970330. PMID: 17330189
Pulmonary sarcoidosis: new genetic clues and ongoing treatment controversies.
Culver DA, Thomassen MJ, Kavuru MS
Cleve Clin J Med 2004 Feb;71(2):88, 90, 92 passim. doi: 10.3949/ccjm.71.2.88. PMID: 14982192

Clinical prediction guides

Granulomatous lung disease in two workers making light bulbs.
Ronsmans S, Verbeken EK, Adams E, Keirsbilck S, Yserbyt J, Wuyts WA, Swennen R, Hoet PH, Nemery B
Am J Ind Med 2019 Oct;62(10):908-913. Epub 2019 Jul 26 doi: 10.1002/ajim.23030. PMID: 31347732
Histological Diagnoses of Military Personnel Undergoing Lung Biopsy After Deployment to Southwest Asia.
Madar CS, Lewin-Smith MR, Franks TJ, Harley RA, Klaric JS, Morris MJ
Lung 2017 Aug;195(4):507-515. Epub 2017 May 23 doi: 10.1007/s00408-017-0009-2. PMID: 28536739
Pulmonary hyalinizing granuloma presenting with dysphagia: a rare presentation.
Khan F, Hamid A, Fatima B, Hashmi S, Fatimi S
Asian Cardiovasc Thorac Ann 2017 Jan;25(1):67-69. Epub 2016 Dec 11 doi: 10.1177/0218492316684983. PMID: 27940652
Granulomatous inflammation of pulmonary squamous cell carcinoma: a rare phenomenon.
Tajima S, Koda K
Int J Clin Exp Pathol 2015;8(6):7547-52. Epub 2015 Jun 1 PMID: 26261667Free PMC Article
Mononuclear phagocyte-derived interleukin-10 suppresses the innate pulmonary granuloma cytokine response in aged mice.
Chiu BC, Stolberg VR, Freeman CM, Chensue SW
Am J Pathol 2007 Sep;171(3):829-37. Epub 2007 Jul 13 doi: 10.2353/ajpath.2007.061122. PMID: 17631521Free PMC Article

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