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Urate tophus

MedGen UID:
67448
•Concept ID:
C0221248
•
Acquired Abnormality
Synonyms: Gouty tophus; Tophus; Tophus co-occurrent and due to gout; Urate tophi
SNOMED CT: Urate tophus (3875003); Gouty tophus (402469004); Tophus co-occurrent and due to gout (402469004); Tophus (240042004); Tophus (3875003); Gouty tophus (3875003)
 
HPO: HP:0033073

Definition

Intradermal urate crystal deposits appeared as small, superficial, pustule-like, whitish lesions. The lesions may be the focus of inflammatory episodes with increasing pain, swelling, and erythema of the intradermal tophi. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUrate tophus

Professional guidelines

PubMed

Concurrent validity of provisional remission criteria for gout: a dual-energy CT study.
Dalbeth N, Frampton C, Fung M, Baumgartner S, Nicolaou S, Choi HK
Arthritis Res Ther 2019 Jun 21;21(1):150. doi: 10.1186/s13075-019-1941-8. PMID: 31227018Free PMC Article

Recent clinical studies

Etiology

Concurrent validity of provisional remission criteria for gout: a dual-energy CT study.
Dalbeth N, Frampton C, Fung M, Baumgartner S, Nicolaou S, Choi HK
Arthritis Res Ther 2019 Jun 21;21(1):150. doi: 10.1186/s13075-019-1941-8. PMID: 31227018Free PMC Article
Unusual presentation of gouty tophus in the liver with subsequent appearance in the same site of HCC: a correlate diagnosis? Case report.
Ministrini S, Baronio G, Zorzi F, Bercich L, Grazioli L, Molfino S, Portolani N
World J Surg Oncol 2019 Jan 8;17(1):10. doi: 10.1186/s12957-018-1546-8. PMID: 30621724Free PMC Article
Progress in measurement instruments for acute and chronic gout studies.
Grainger R, Taylor WJ, Dalbeth N, Perez-Ruiz F, Singh JA, Waltrip RW, Schlesinger N, Evans R, Edwards NL, Sivera F, Diaz-Torne C, MacDonald PA, McQueen FM, Schumacher HR
J Rheumatol 2009 Oct;36(10):2346-55. doi: 10.3899/jrheum.090371. PMID: 19820224

Diagnosis

Concurrent validity of provisional remission criteria for gout: a dual-energy CT study.
Dalbeth N, Frampton C, Fung M, Baumgartner S, Nicolaou S, Choi HK
Arthritis Res Ther 2019 Jun 21;21(1):150. doi: 10.1186/s13075-019-1941-8. PMID: 31227018Free PMC Article
Unusual presentation of gouty tophus in the liver with subsequent appearance in the same site of HCC: a correlate diagnosis? Case report.
Ministrini S, Baronio G, Zorzi F, Bercich L, Grazioli L, Molfino S, Portolani N
World J Surg Oncol 2019 Jan 8;17(1):10. doi: 10.1186/s12957-018-1546-8. PMID: 30621724Free PMC Article
Comparison of dual-energy CT, ultrasound and surface measurement for assessing tophus dissolution during rapid urate debulking.
Modjinou DV, Krasnokutsky S, Gyftopoulos S, Pike VC, Karis E, Keenan RT, Lee K, Crittenden DB, Samuels J, Pillinger MH
Clin Rheumatol 2017 Sep;36(9):2101-2107. Epub 2017 Jun 16 doi: 10.1007/s10067-017-3729-z. PMID: 28623421
Progress in measurement instruments for acute and chronic gout studies.
Grainger R, Taylor WJ, Dalbeth N, Perez-Ruiz F, Singh JA, Waltrip RW, Schlesinger N, Evans R, Edwards NL, Sivera F, Diaz-Torne C, MacDonald PA, McQueen FM, Schumacher HR
J Rheumatol 2009 Oct;36(10):2346-55. doi: 10.3899/jrheum.090371. PMID: 19820224

Therapy

Concurrent validity of provisional remission criteria for gout: a dual-energy CT study.
Dalbeth N, Frampton C, Fung M, Baumgartner S, Nicolaou S, Choi HK
Arthritis Res Ther 2019 Jun 21;21(1):150. doi: 10.1186/s13075-019-1941-8. PMID: 31227018Free PMC Article
Unusual presentation of gouty tophus in the liver with subsequent appearance in the same site of HCC: a correlate diagnosis? Case report.
Ministrini S, Baronio G, Zorzi F, Bercich L, Grazioli L, Molfino S, Portolani N
World J Surg Oncol 2019 Jan 8;17(1):10. doi: 10.1186/s12957-018-1546-8. PMID: 30621724Free PMC Article
Comparison of dual-energy CT, ultrasound and surface measurement for assessing tophus dissolution during rapid urate debulking.
Modjinou DV, Krasnokutsky S, Gyftopoulos S, Pike VC, Karis E, Keenan RT, Lee K, Crittenden DB, Samuels J, Pillinger MH
Clin Rheumatol 2017 Sep;36(9):2101-2107. Epub 2017 Jun 16 doi: 10.1007/s10067-017-3729-z. PMID: 28623421

Prognosis

Concurrent validity of provisional remission criteria for gout: a dual-energy CT study.
Dalbeth N, Frampton C, Fung M, Baumgartner S, Nicolaou S, Choi HK
Arthritis Res Ther 2019 Jun 21;21(1):150. doi: 10.1186/s13075-019-1941-8. PMID: 31227018Free PMC Article

Clinical prediction guides

Concurrent validity of provisional remission criteria for gout: a dual-energy CT study.
Dalbeth N, Frampton C, Fung M, Baumgartner S, Nicolaou S, Choi HK
Arthritis Res Ther 2019 Jun 21;21(1):150. doi: 10.1186/s13075-019-1941-8. PMID: 31227018Free PMC Article

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