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Chronic discoid lupus erythematosus

MedGen UID:
7402
Concept ID:
C0024138
Disease or Syndrome
Synonyms: Discoid Lupus Erythematosus; Lupus Erythematosus, Chronic Cutaneous; Lupus Erythematosus, Cutaneous, Chronic; Lupus Erythematosus, Discoid
SNOMED CT: CDLE - Chronic discoid lupus erythematosus (238927000); Chronic discoid lupus erythematosus (238927000)

Definition

A chronic, autoimmune skin condition that manifests with a red, scaling rash, most often found on the face, ears, and scalp; these lesions often lead to permanent scarring and dyspigmentation. Patients may have lesions with or without other symptoms or antibodies suggestive of systemic lupus erythematosus (SLE). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChronic discoid lupus erythematosus
Follow this link to review classifications for Chronic discoid lupus erythematosus in Orphanet.

Professional guidelines

PubMed

Erceg A, Bovenschen HJ, van de Kerkhof PC, de Jong EM, Seyger MM
J Am Acad Dermatol 2009 Apr;60(4):626-32. doi: 10.1016/j.jaad.2008.11.904. PMID: 19293010
Knop J, Bonsmann G, Happle R, Ludolph A, Matz DR, Mifsud EJ, Macher E
Br J Dermatol 1983 Apr;108(4):461-6. doi: 10.1111/j.1365-2133.1983.tb04600.x. PMID: 6838771
GOLDMAN L
J Invest Dermatol 1948 Aug;11(2):95. doi: 10.1038/jid.1948.74. PMID: 18877035

Recent clinical studies

Etiology

Klein A, Coras B, Landthaler M, Babilas P
J Eur Acad Dermatol Venereol 2012 Nov;26(11):1400-6. Epub 2011 Oct 18 doi: 10.1111/j.1468-3083.2011.04303.x. PMID: 22007931
Erceg A, Bovenschen HJ, van de Kerkhof PC, de Jong EM, Seyger MM
J Am Acad Dermatol 2009 Apr;60(4):626-32. doi: 10.1016/j.jaad.2008.11.904. PMID: 19293010
Shahidullah M, Lee YS, Khor CJ, Ratnam KV
Ann Acad Med Singap 1995 Nov;24(6):789-92. PMID: 8838982
Halder RM, Bridgeman-Shah S
Cancer 1995 Jan 15;75(2 Suppl):667-73. doi: 10.1002/1097-0142(19950115)75:2+<667::aid-cncr2820751409>3.0.co;2-i. PMID: 7804993
Nordström RE
Scand J Plast Reconstr Surg Suppl 1976;14:1-37. PMID: 1032729

Diagnosis

Erceg A, De Jong EM, Van Lingen RG, De Boo TM, Van De Kerkhof PC, Seyger MM
J Dermatolog Treat 2009;20(1):32-5. doi: 10.1080/09546630802155040. PMID: 18608708
Fabbri P, Amato L, Chiarini C, Moretti S, Massi D
Lupus 2004;13(6):455-62. doi: 10.1191/0961203304lu1041oa. PMID: 15303573
Pramatarov KD
Clin Dermatol 2004 Mar-Apr;22(2):113-20. doi: 10.1016/j.clindermatol.2003.12.016. PMID: 15234011
Rupec RA, Petropoulou T, Belohradsky BH, Walchner M, Liese JG, Plewing G, Messer G
Eur J Dermatol 2000 Apr-May;10(3):184-9. PMID: 10725815
Ruffatti A, Veller-Fornasa C, Patrassi GM, Sartori E, Tonello M, Tonetto S, Peserico A, Todesco S
Clin Rheumatol 1995 Jul;14(4):402-4. doi: 10.1007/BF02207672. PMID: 7586975

Therapy

Steinbronn C, Chhonker YS, Stewart J, Leingang H, Heller KB, Krows ML, Paasche-Orlow M, Bershteyn A, Stankiewicz Karita HC, Agrawal V, Laufer M, Landovitz R, Wener M, Murry DJ, Johnston C, Barnabas RV, Arnold SLM
Clin Transl Sci 2023 Jul;16(7):1243-1257. Epub 2023 Apr 29 doi: 10.1111/cts.13527. PMID: 37118968Free PMC Article
Jin X, Lu S, Xing X, Wang L, Mu D, He M, Huang H, Zeng X, Chen Q
J Oral Pathol Med 2013 May;42(5):355-62. Epub 2012 Sep 17 doi: 10.1111/jop.12004. PMID: 22978368
Perri AJ 3rd, Hsu S
Dermatol Online J 2003 Aug;9(3):5. PMID: 12952752
Kyriakis KP, Kontochristopoulos GJ, Panteleos DN
Int J Dermatol 2000 Mar;39(3):218-22. doi: 10.1046/j.1365-4362.2000.00953.x. PMID: 10759967
Winkelmann RK
JAMA 1968 Sep 2;205(10):675-8. PMID: 5695138

Prognosis

Dadlani C, Pulitzer M, Prystowsky SD
Dermatol Online J 2008 May 15;14(5):5. PMID: 18627741
Kyriakis KP, Kontochristopoulos GJ, Panteleos DN
Int J Dermatol 2000 Mar;39(3):218-22. doi: 10.1046/j.1365-4362.2000.00953.x. PMID: 10759967
Halder RM, Bridgeman-Shah S
Cancer 1995 Jan 15;75(2 Suppl):667-73. doi: 10.1002/1097-0142(19950115)75:2+<667::aid-cncr2820751409>3.0.co;2-i. PMID: 7804993
Gubner R
Arch Dermatol 1983 Jun;119(6):513-24. PMID: 6859892
Callen JP
Arch Dermatol 1982 Jun;118(6):412-6. doi: 10.1001/archderm.118.6.412. PMID: 7092253

Clinical prediction guides

Steinbronn C, Chhonker YS, Stewart J, Leingang H, Heller KB, Krows ML, Paasche-Orlow M, Bershteyn A, Stankiewicz Karita HC, Agrawal V, Laufer M, Landovitz R, Wener M, Murry DJ, Johnston C, Barnabas RV, Arnold SLM
Clin Transl Sci 2023 Jul;16(7):1243-1257. Epub 2023 Apr 29 doi: 10.1111/cts.13527. PMID: 37118968Free PMC Article
Weiss A, Kwon EJ, Kreidel M, Mann R, Cohen JA, Hui Y, Jacobson MI
Am J Dermatopathol 2020 Feb;42(2):129-132. doi: 10.1097/DAD.0000000000001510. PMID: 31464721
Gambichler T, Terras S, Kampilafkos P, Kreuter A, Skrygan M
Br J Dermatol 2013 Dec;169(6):1288-94. doi: 10.1111/bjd.12608. PMID: 24032533
Kulthanan K, Roongphiboolsopit P, Chanjanakijskul S, Kullavanijaya P
Int J Dermatol 1996 Oct;35(10):711-4. doi: 10.1111/j.1365-4362.1996.tb00643.x. PMID: 8891819
Gubner R
Arch Dermatol 1983 Jun;119(6):513-24. PMID: 6859892

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