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Solitary osseous plasmacytoma

MedGen UID:
75777
•Concept ID:
C0272256
•
Neoplastic Process
Synonyms: Bone Solitary Plasmacytoma; isolated osseous plasmacytoma; isolated plasmacytoma of bone; Monostotic myeloma; Solitary osseous myeloma; solitary osseous plasmacytoma; Solitary plasmacytoma of bone; Solitary Plasmacytoma of Bone; solitary plasmacytoma of bone; SOM disease; SPB
SNOMED CT: Solitary plasmacytoma of bone (426336007); Monostotic myeloma (426336007); Solitary osseous myeloma (426336007); SOM disease (426336007)
 
Monarch Initiative: MONDO:0002755

Definition

A localized malignant neoplasm that arises in the bone. It is composed of clonal (malignant) plasma cells forming a tumor mass. The most commonly affected bones are the vertebrae, ribs, skull, pelvis, and femur. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSolitary osseous plasmacytoma

Professional guidelines

PubMed

Solitary plasmacytoma: population-based analysis of survival trends and effect of various treatment modalities in the USA.
Thumallapally N, Meshref A, Mousa M, Terjanian T
BMC Cancer 2017 Jan 5;17(1):13. doi: 10.1186/s12885-016-3015-5. PMID: 28056880Free PMC Article
Solitary plasmacytoma of cervical spine: treatment and prognosis in patients with neurological lesions and spinal instability.
Huang W, Cao D, Ma J, Yang X, Xiao J, Zheng W, Feng D, Wu Z, Huang Q, Chen D, Jia L
Spine (Phila Pa 1976) 2010 Apr 15;35(8):E278-84. doi: 10.1097/BRS.0b013e3181c9b431. PMID: 20228695
Radiotherapy in the management of plasma cell tumors.
Hu K, Yahalom J
Oncology (Williston Park) 2000 Jan;14(1):101-8, 111; discussion 111-2, 115. PMID: 10680152

Recent clinical studies

Diagnosis

Gradenigo's syndrome as first presentation of solitary osseous plasmacytoma of the petrous apex.
Khalatbari MR, Hamidi M, Moharamzad Y
Arch Iran Med 2014 Jul;17(7):526-8. PMID: 24979569
Solitary plasmacytoma of the index finger.
Daneshbod Y, Nowshadi PA, Negahban S, Aledavood A, Ramzi M, Fanaie S, Bedayat G, Medeiros LJ
J Clin Pathol 2014 Sep;67(9):828-31. doi: 10.1136/jclinpath-2014-202413. PMID: 24964361
Nasal septum extramedullary plasmacytoma.
Belić B, Mitrović S, Arsenijević S, Erdevicki L, Stojanović J, Stojanović S, Stolić R
Vojnosanit Pregl 2013 Feb;70(2):221-4. doi: 10.2298/vsp1302221b. PMID: 23607192
Solitary osseous plasmacytoma of the orbit with amyloidosis.
Rawlings NG, Brownstein S, Robinson JW, Jordan DR
Ophthalmic Plast Reconstr Surg 2007 Jan-Feb;23(1):79-80. doi: 10.1097/IOP.0b013e31802c7e6e. PMID: 17237706
Brain necrosis after permanent low-activity iodine-125 implants: case report and review of toxicity from focal radiation.
Bampoe J, Nag S, Leung P, Laperriere N, Bernstein M
Brain Tumor Pathol 2000;17(3):139-45. doi: 10.1007/BF02484285. PMID: 11310921

Therapy

Brain necrosis after permanent low-activity iodine-125 implants: case report and review of toxicity from focal radiation.
Bampoe J, Nag S, Leung P, Laperriere N, Bernstein M
Brain Tumor Pathol 2000;17(3):139-45. doi: 10.1007/BF02484285. PMID: 11310921

Prognosis

Solitary osseous plasmacytoma of the orbit with amyloidosis.
Rawlings NG, Brownstein S, Robinson JW, Jordan DR
Ophthalmic Plast Reconstr Surg 2007 Jan-Feb;23(1):79-80. doi: 10.1097/IOP.0b013e31802c7e6e. PMID: 17237706
Brain necrosis after permanent low-activity iodine-125 implants: case report and review of toxicity from focal radiation.
Bampoe J, Nag S, Leung P, Laperriere N, Bernstein M
Brain Tumor Pathol 2000;17(3):139-45. doi: 10.1007/BF02484285. PMID: 11310921

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