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Pre-Gestational Diabetes

MedGen UID:
821240
•Concept ID:
C3828492
•
Disease or Syndrome
Synonym: Pregestational Diabetes

Definition

Diabetes diagnosed before current pregnancy. (reVITALize) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPre-Gestational Diabetes

Professional guidelines

PubMed

Type 1 Diabetes in Pregnancy: A Review of Complications and Management.
Jaffar F, Laycock K, Huda MSB
Curr Diabetes Rev 2022;18(7):e051121197761. doi: 10.2174/1573399818666211105124829. PMID: 34749617
Neonatal management of pregnancy complicated by diabetes.
Mohsin F, Khan S, Baki MA, Zabeen B, Azad K
J Pak Med Assoc 2016 Sep;66(9 Suppl 1):S81-4. PMID: 27582162
Effect of screening and management of diabetes during pregnancy on stillbirths.
Syed M, Javed H, Yakoob MY, Bhutta ZA
BMC Public Health 2011 Apr 13;11 Suppl 3(Suppl 3):S2. doi: 10.1186/1471-2458-11-S3-S2. PMID: 21501437Free PMC Article

Recent clinical studies

Etiology

Attendance at pre-pregnancy care clinics for women with type 1 diabetes: A scoping review.
Ferry P, Dunne FP, Meagher C, Lennon R, Egan AM, Newman C
Diabet Med 2023 Mar;40(3):e15014. Epub 2022 Nov 28 doi: 10.1111/dme.15014. PMID: 36408687Free PMC Article
Glycated albumin and continuous glucose monitoring metrics across pregnancy in women with pre-gestational diabetes.
Toft JH, Dalen I, Skadberg Ø, Gøransson LG, Økland I, Bleskestad IH
Endocrinol Diabetes Metab 2022 Nov;5(6):e376. Epub 2022 Sep 19 doi: 10.1002/edm2.376. PMID: 36121204Free PMC Article
Derivation and assessment of a sex-specific fetal growth standard.
Blue NR, Allshouse AA, Heerboth S, Grobman W, Mercer B, Shanks A, Bregand-White JM, Simhan H, Reddy UM, Saade G, Parry S, Silver RM
J Matern Fetal Neonatal Med 2022 Dec;35(25):9913-9921. Epub 2022 May 22 doi: 10.1080/14767058.2022.2075696. PMID: 35603475
The association between gestational diabetes and ASD and ADHD: a systematic review and meta-analysis.
Rowland J, Wilson CA
Sci Rep 2021 Mar 4;11(1):5136. doi: 10.1038/s41598-021-84573-3. PMID: 33664319Free PMC Article
Leukocyte Telomere Length in the Neonatal Offspring of Mothers with Gestational and Pre-Gestational Diabetes.
Gilfillan C, Naidu P, Gunawan F, Hassan F, Tian P, Elwood N
PLoS One 2016;11(10):e0163824. Epub 2016 Oct 13 doi: 10.1371/journal.pone.0163824. PMID: 27736899Free PMC Article

Diagnosis

Associations between maternal metabolic conditions and neurodevelopmental conditions in offspring: the mediating effects of obstetric and neonatal complications.
Chen S, Wang X, Lee BK, Gardner RM
BMC Med 2023 Nov 7;21(1):422. doi: 10.1186/s12916-023-03116-x. PMID: 37936224Free PMC Article
Glycated albumin and continuous glucose monitoring metrics across pregnancy in women with pre-gestational diabetes.
Toft JH, Dalen I, Skadberg Ø, Gøransson LG, Økland I, Bleskestad IH
Endocrinol Diabetes Metab 2022 Nov;5(6):e376. Epub 2022 Sep 19 doi: 10.1002/edm2.376. PMID: 36121204Free PMC Article
Derivation and assessment of a sex-specific fetal growth standard.
Blue NR, Allshouse AA, Heerboth S, Grobman W, Mercer B, Shanks A, Bregand-White JM, Simhan H, Reddy UM, Saade G, Parry S, Silver RM
J Matern Fetal Neonatal Med 2022 Dec;35(25):9913-9921. Epub 2022 May 22 doi: 10.1080/14767058.2022.2075696. PMID: 35603475
Systematic review and meta-analysis of the effectiveness of pre-pregnancy care for women with diabetes for improving maternal and perinatal outcomes.
Wahabi HA, Fayed A, Esmaeil S, Elmorshedy H, Titi MA, Amer YS, Alzeidan RA, Alodhayani AA, Saeed E, Bahkali KH, Kahili-Heede MK, Jamal A, Sabr Y
PLoS One 2020;15(8):e0237571. Epub 2020 Aug 18 doi: 10.1371/journal.pone.0237571. PMID: 32810195Free PMC Article
Maternal factors, ultrasound and placental function parameters in early pregnancy as predictors of birth weight in low-risk populations and among patients with pre-gestational diabetes.
Gasiorowska A, Zawiejska A, Dydowicz P, Wender-Ozegowska E, Poprawski G, Tobola-Wrobel K, Ziolkowska K, Pietryga M
Ginekol Pol 2019;90(7):388-395. doi: 10.5603/GP.2019.0067. PMID: 31392708

Therapy

Comparison of insulin requirements across gestation in women with hyperglycemia in pregnancy: A prospective cohort study.
Rao C, Ping F
Front Endocrinol (Lausanne) 2022;13:1013663. Epub 2022 Oct 20 doi: 10.3389/fendo.2022.1013663. PMID: 36339424Free PMC Article
Impact of the Dietary Approaches to Stop Hypertension (DASH) diet on glycaemic control and consumption of processed and ultraprocessed foods in pregnant women with pre-gestational diabetes mellitus: a randomised clinical trial.
Fagherazzi S, Farias DR, Belfort GP, Dos Santos K, Santana Vieira de Lima T, Silva Dos Santos M, Saunders C
Br J Nutr 2021 Sep 28;126(6):865-876. Epub 2020 Dec 1 doi: 10.1017/S0007114520004791. PMID: 33256869
Allopurinol inhibits excess glucose-induced trophoblast IL-1β and ROS production.
Negi M, Mulla MJ, Han CS, Abrahams VM
Reproduction 2020 Jan;159(1):73-80. doi: 10.1530/REP-19-0422. PMID: 31705795
Continuous subcutaneous insulin infusion versus multiple daily injections of insulin for pregnant women with diabetes.
Farrar D, Tuffnell DJ, West J, West HM
Cochrane Database Syst Rev 2016 Jun 7;2016(6):CD005542. doi: 10.1002/14651858.CD005542.pub3. PMID: 27272351Free PMC Article
Continuous subcutaneous insulin infusion versus multiple daily injections of insulin for pregnant women with diabetes.
Farrar D, Tuffnell DJ, West J
Cochrane Database Syst Rev 2007 Jul 18;(3):CD005542. doi: 10.1002/14651858.CD005542.pub2. PMID: 17636806

Prognosis

Pregnancy costs with commercial insurance.
Rahman M, Chen L, Daw J, Wright JD, D'Alton ME, Wen T, Friedman AM
J Matern Fetal Neonatal Med 2022 Dec;35(25):10143-10151. Epub 2022 Sep 14 doi: 10.1080/14767058.2022.2122037. PMID: 36104042
Diabetes in Pregnancy: Preconception to Postpartum.
Healy AM
Prim Care 2022 Jun;49(2):287-300. Epub 2022 Apr 13 doi: 10.1016/j.pop.2021.11.009. PMID: 35595483
Incidence, Risk Factors, and Outcomes of Preterm and Early Term Births: A Population-Based Register Study.
Younes S, Samara M, Al-Jurf R, Nasrallah G, Al-Obaidly S, Salama H, Olukade T, Hammuda S, Ismail MA, Abdoh G, Abdulrouf PV, Farrell T, AlQubaisi M, Al Rifai H, Al-Dewik N
Int J Environ Res Public Health 2021 May 29;18(11) doi: 10.3390/ijerph18115865. PMID: 34072575Free PMC Article
Systematic review and meta-analysis of the effectiveness of pre-pregnancy care for women with diabetes for improving maternal and perinatal outcomes.
Wahabi HA, Fayed A, Esmaeil S, Elmorshedy H, Titi MA, Amer YS, Alzeidan RA, Alodhayani AA, Saeed E, Bahkali KH, Kahili-Heede MK, Jamal A, Sabr Y
PLoS One 2020;15(8):e0237571. Epub 2020 Aug 18 doi: 10.1371/journal.pone.0237571. PMID: 32810195Free PMC Article
Maternal factors, ultrasound and placental function parameters in early pregnancy as predictors of birth weight in low-risk populations and among patients with pre-gestational diabetes.
Gasiorowska A, Zawiejska A, Dydowicz P, Wender-Ozegowska E, Poprawski G, Tobola-Wrobel K, Ziolkowska K, Pietryga M
Ginekol Pol 2019;90(7):388-395. doi: 10.5603/GP.2019.0067. PMID: 31392708

Clinical prediction guides

Pregnancy costs with commercial insurance.
Rahman M, Chen L, Daw J, Wright JD, D'Alton ME, Wen T, Friedman AM
J Matern Fetal Neonatal Med 2022 Dec;35(25):10143-10151. Epub 2022 Sep 14 doi: 10.1080/14767058.2022.2122037. PMID: 36104042
Delivery indication matters for perinatal outcomes in late preterm newborns.
Monari F, Chiossi G, Gargano G, Ballarini M, Baronciani D, Coscia A, Facchinetti F
J Matern Fetal Neonatal Med 2022 Dec;35(25):8257-8266. Epub 2022 Jan 25 doi: 10.1080/14767058.2021.1969358. PMID: 35078377
Incidence, Risk Factors, and Outcomes of Preterm and Early Term Births: A Population-Based Register Study.
Younes S, Samara M, Al-Jurf R, Nasrallah G, Al-Obaidly S, Salama H, Olukade T, Hammuda S, Ismail MA, Abdoh G, Abdulrouf PV, Farrell T, AlQubaisi M, Al Rifai H, Al-Dewik N
Int J Environ Res Public Health 2021 May 29;18(11) doi: 10.3390/ijerph18115865. PMID: 34072575Free PMC Article
Systematic review and meta-analysis of the effectiveness of pre-pregnancy care for women with diabetes for improving maternal and perinatal outcomes.
Wahabi HA, Fayed A, Esmaeil S, Elmorshedy H, Titi MA, Amer YS, Alzeidan RA, Alodhayani AA, Saeed E, Bahkali KH, Kahili-Heede MK, Jamal A, Sabr Y
PLoS One 2020;15(8):e0237571. Epub 2020 Aug 18 doi: 10.1371/journal.pone.0237571. PMID: 32810195Free PMC Article
Fetal overgrowth in pregnancies complicated by diabetes: development of a clinical prediction index.
Tomlinson TM, Mostello DJ, Lim KH, Pritchard JS, Gross G
Arch Gynecol Obstet 2018 Jul;298(1):67-74. Epub 2018 Apr 26 doi: 10.1007/s00404-018-4758-9. PMID: 29700600

Recent systematic reviews

The association between gestational diabetes and ASD and ADHD: a systematic review and meta-analysis.
Rowland J, Wilson CA
Sci Rep 2021 Mar 4;11(1):5136. doi: 10.1038/s41598-021-84573-3. PMID: 33664319Free PMC Article
Systematic review and meta-analysis of the effectiveness of pre-pregnancy care for women with diabetes for improving maternal and perinatal outcomes.
Wahabi HA, Fayed A, Esmaeil S, Elmorshedy H, Titi MA, Amer YS, Alzeidan RA, Alodhayani AA, Saeed E, Bahkali KH, Kahili-Heede MK, Jamal A, Sabr Y
PLoS One 2020;15(8):e0237571. Epub 2020 Aug 18 doi: 10.1371/journal.pone.0237571. PMID: 32810195Free PMC Article
Early Gestational Diabetes Mellitus Screening With Glycated Hemoglobin: A Systematic Review.
Kattini R, Hummelen R, Kelly L
J Obstet Gynaecol Can 2020 Nov;42(11):1379-1384. Epub 2020 Apr 6 doi: 10.1016/j.jogc.2019.12.015. PMID: 32268994
Continuous subcutaneous insulin infusion versus multiple daily injections of insulin for pregnant women with diabetes.
Farrar D, Tuffnell DJ, West J, West HM
Cochrane Database Syst Rev 2016 Jun 7;2016(6):CD005542. doi: 10.1002/14651858.CD005542.pub3. PMID: 27272351Free PMC Article
Continuous subcutaneous insulin infusion versus multiple daily injections of insulin for pregnant women with diabetes.
Farrar D, Tuffnell DJ, West J
Cochrane Database Syst Rev 2007 Jul 18;(3):CD005542. doi: 10.1002/14651858.CD005542.pub2. PMID: 17636806

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