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Epidural abscess

MedGen UID:
82848
Concept ID:
C0270629
Disease or Syndrome
Synonyms: Abscess, Epidural; Abscess, Extradural; Epidural Abscess; Extradural Abscess
SNOMED CT: Epidural abscess (61974008); Extradural abscess (61974008)
 
Monarch Initiative: MONDO:0005752

Definition

Circumscribed collections of suppurative material occurring in the spinal or intracranial epidural space. The majority of epidural abscesses occur in the spinal canal and are associated with osteomyelitis of a vertebral body; analgesia, epidural; and other conditions. Clinical manifestations include local and radicular pain, weakness, sensory loss, urinary incontinence, and fecal incontinence. Cranial epidural abscesses are usually associated with osteomyelitis of a cranial bone, sinusitis, or otitis media. (From Adams et al., Principles of Neurology, 6th ed, p710 and pp1240-1; J Neurol Neurosurg Psychiatry 1998 Aug;65(2):209-12) [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEpidural abscess

Professional guidelines

PubMed

Schwab JH, Shah AA
J Am Acad Orthop Surg 2020 Nov 1;28(21):e929-e938. doi: 10.5435/JAAOS-D-19-00685. PMID: 32694325
Lener S, Hartmann S, Barbagallo GMV, Certo F, Thomé C, Tschugg A
Acta Neurochir (Wien) 2018 Mar;160(3):487-496. Epub 2018 Jan 22 doi: 10.1007/s00701-018-3467-2. PMID: 29356895Free PMC Article
David MZ, Daum RS
Curr Top Microbiol Immunol 2017;409:325-383. doi: 10.1007/82_2017_42. PMID: 28900682

Recent clinical studies

Etiology

Kuris EO, McDonald CL, Palumbo MA, Daniels AH
Am J Med 2021 Dec;134(12):1483-1489. Epub 2021 Aug 30 doi: 10.1016/j.amjmed.2021.07.021. PMID: 34473966
Schwab JH, Shah AA
J Am Acad Orthop Surg 2020 Nov 1;28(21):e929-e938. doi: 10.5435/JAAOS-D-19-00685. PMID: 32694325
Galliker G, Scherer DE, Trippolini MA, Rasmussen-Barr E, LoMartire R, Wertli MM
Am J Med 2020 Jan;133(1):60-72.e14. Epub 2019 Jul 3 doi: 10.1016/j.amjmed.2019.06.005. PMID: 31278933
Bodur H, Erbay A, Colpan A, Akinci E
Rheumatol Int 2004 Jul;24(4):221-6. Epub 2003 Jul 16 doi: 10.1007/s00296-003-0350-z. PMID: 12879273
Ho G Jr
Curr Opin Rheumatol 1991 Aug;3(4):603-9. doi: 10.1097/00002281-199108000-00009. PMID: 1911055

Diagnosis

Vaphiades MS, Isen D, Tavakoli M, Bilyk JR
Surv Ophthalmol 2023 Jul-Aug;68(4):830-833. Epub 2022 Nov 23 doi: 10.1016/j.survophthal.2022.11.005. PMID: 36427561
Tomoye EO, Moon RE
Undersea Hyperb Med 2021 First Quarter;48(1):97-102. doi: 10.22462/01.03.2021.12. PMID: 33648039
Schwab JH, Shah AA
J Am Acad Orthop Surg 2020 Nov 1;28(21):e929-e938. doi: 10.5435/JAAOS-D-19-00685. PMID: 32694325
Ropper AE, Ropper AH
N Engl J Med 2017 Apr 6;376(14):1358-1369. doi: 10.1056/NEJMra1516539. PMID: 28379788
Darouiche RO
N Engl J Med 2006 Nov 9;355(19):2012-20. doi: 10.1056/NEJMra055111. PMID: 17093252

Therapy

Schwab JH, Shah AA
J Am Acad Orthop Surg 2020 Nov 1;28(21):e929-e938. doi: 10.5435/JAAOS-D-19-00685. PMID: 32694325
Cornett CA, Vincent SA, Crow J, Hewlett A
J Am Acad Orthop Surg 2016 Jan;24(1):11-8. doi: 10.5435/JAAOS-D-13-00102. PMID: 26700630
Stoffel M, Stüer C, Ringel F, Meyer B
Adv Tech Stand Neurosurg 2011;(37):213-43. doi: 10.1007/978-3-7091-0673-0_7. PMID: 21997745
Darouiche RO
N Engl J Med 2006 Nov 9;355(19):2012-20. doi: 10.1056/NEJMra055111. PMID: 17093252
Sethi A, Sabherwal A, Gulati A, Sareen D
Acta Otolaryngol 2005 Nov;125(11):1236-9. doi: 10.1080/00016480510038158. PMID: 16353409

Prognosis

Garg RK, Paliwal VK, Gupta A
J Spinal Cord Med 2023 May;46(3):390-404. Epub 2021 Mar 11 doi: 10.1080/10790268.2021.1888022. PMID: 33705268Free PMC Article
Schwab JH, Shah AA
J Am Acad Orthop Surg 2020 Nov 1;28(21):e929-e938. doi: 10.5435/JAAOS-D-19-00685. PMID: 32694325
Lener S, Hartmann S, Barbagallo GMV, Certo F, Thomé C, Tschugg A
Acta Neurochir (Wien) 2018 Mar;160(3):487-496. Epub 2018 Jan 22 doi: 10.1007/s00701-018-3467-2. PMID: 29356895Free PMC Article
Aleman-Ortega H, Lee R, Shambo L, Czinn E
AORN J 2017 Feb;105(2):184-192. doi: 10.1016/j.aorn.2016.12.004. PMID: 28159077
Jay CA, Solbrig MV
Handb Clin Neurol 2014;126:175-94. doi: 10.1016/B978-0-444-53480-4.00014-X. PMID: 25410222

Clinical prediction guides

Schwab JH, Shah AA
J Am Acad Orthop Surg 2020 Nov 1;28(21):e929-e938. doi: 10.5435/JAAOS-D-19-00685. PMID: 32694325
Hammad A, Wirries A, Ardeshiri A, Nikiforov O, Geiger F
J Orthop Surg Res 2019 Jul 22;14(1):229. doi: 10.1186/s13018-019-1266-y. PMID: 31331364Free PMC Article
Duarte RM, Vaccaro AR
Eur Spine J 2013 Dec;22(12):2787-99. Epub 2013 Jun 12 doi: 10.1007/s00586-013-2850-1. PMID: 23756630Free PMC Article
Bodur H, Erbay A, Colpan A, Akinci E
Rheumatol Int 2004 Jul;24(4):221-6. Epub 2003 Jul 16 doi: 10.1007/s00296-003-0350-z. PMID: 12879273
Weprin BE, Oakes WJ
Pediatrics 2000 May;105(5):E69. doi: 10.1542/peds.105.5.e69. PMID: 10799633

Recent systematic reviews

Sheybani F, Figueiredo AHA, Brouwer MC, van de Beek D
Int J Infect Dis 2021 Oct;111:354-359. Epub 2021 Sep 4 doi: 10.1016/j.ijid.2021.08.069. PMID: 34487853
Beit Ner E, Chechik Y, Lambert LA, Anekstein Y, Mirovsky Y, Smorgick Y
Eur Spine J 2021 Jun;30(6):1708-1720. Epub 2020 Oct 27 doi: 10.1007/s00586-020-06646-7. PMID: 33108532
Galliker G, Scherer DE, Trippolini MA, Rasmussen-Barr E, LoMartire R, Wertli MM
Am J Med 2020 Jan;133(1):60-72.e14. Epub 2019 Jul 3 doi: 10.1016/j.amjmed.2019.06.005. PMID: 31278933
Verdú-López F, Vanaclocha-Vanaclocha V, Mayorga-Villa JD
J Neurosurg Sci 2017 Jun;61(3):303-315. Epub 2016 Oct 27 doi: 10.23736/S0390-5616.16.03911-4. PMID: 27787487
Korovessis P, Vardakastanis K, Fennema P, Syrimbeis V
Eur J Orthop Surg Traumatol 2016 Oct;26(7):753-61. Epub 2016 Jun 20 doi: 10.1007/s00590-016-1803-x. PMID: 27324195

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