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Atypical glandular hyperplasia

MedGen UID:
83099
•Concept ID:
C0334001
•
Pathologic Function
Synonyms: Atypical adenomatous hyperplasia; Atypical Glandular Hyperplasia
SNOMED CT: Atypical glandular hyperplasia (17474009); Atypical adenomatous hyperplasia (17474009)

Definition

Proliferation of glandular epithelial cells associated with the presence of cytologic atypia and architectural growth pattern changes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAtypical glandular hyperplasia

Professional guidelines

PubMed

Immunohistochemical staining for Ki-67 antigen, carcinoembryonic antigen, and p53 in the differential diagnosis of glandular lesions of the cervix.
Cina SJ, Richardson MS, Austin RM, Kurman RJ
Mod Pathol 1997 Mar;10(3):176-80. PMID: 9071723
Diagnostic histologic criteria of atypical adenomatous hyperplasia and well differentiated adenocarcinoma of the endometrium.
Liapis A, Pafitis A, Hassiakos D, Chirakis M, Zourlas PA
Eur J Gynaecol Oncol 1994;15(6):464-8. PMID: 7875162

Recent clinical studies

Diagnosis

Immunohistochemical staining for Ki-67 antigen, carcinoembryonic antigen, and p53 in the differential diagnosis of glandular lesions of the cervix.
Cina SJ, Richardson MS, Austin RM, Kurman RJ
Mod Pathol 1997 Mar;10(3):176-80. PMID: 9071723
Diagnostic histologic criteria of atypical adenomatous hyperplasia and well differentiated adenocarcinoma of the endometrium.
Liapis A, Pafitis A, Hassiakos D, Chirakis M, Zourlas PA
Eur J Gynaecol Oncol 1994;15(6):464-8. PMID: 7875162
Morular metaplasia misdiagnosed as adenoacanthoma in young women with polycystic ovarian disease.
Blaustein A
Am J Surg Pathol 1982 Apr;6(3):223-8. doi: 10.1097/00000478-198204000-00004. PMID: 7102901

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