U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Orbit Capillary Hemangioma

MedGen UID:
83421
•Concept ID:
C0346351
•
Neoplastic Process
Synonyms: Capillary Angioma of Orbit; Capillary Angioma of the Orbit; Capillary hemangioma of orbit; Capillary Hemangioma of Orbit; Capillary Hemangioma of the Orbit; Orbit Capillary Angioma
SNOMED CT: Capillary hemangioma of orbit (254997007)

Definition

A capillary hemangioma arising from the orbit. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOrbit Capillary Hemangioma

Professional guidelines

PubMed

Retrobulbar Hemangioblastomas in von Hippel-Lindau Disease: Clinical Course and Management.
Alvarez R, Mastorakos P, Hogan E, Scott G, Lonser RR, Wiley HE, Chew EY, Chittiboina P
Neurosurgery 2021 Apr 15;88(5):1012-1020. doi: 10.1093/neuros/nyaa565. PMID: 33442737Free PMC Article
β-blockers in the treatment of periocular infantile hemangioma.
Al-Haddad C, El Salloukh NA, El Moussawi Z
Curr Opin Ophthalmol 2019 Sep;30(5):319-325. doi: 10.1097/ICU.0000000000000591. PMID: 31394556
New developments in the management of periocular capillary hemangioma in children.
Ni N, Wagner RS, Langer P, Guo S
J Pediatr Ophthalmol Strabismus 2011 Sep-Oct;48(5):269-76; quiz 268, 277. Epub 2010 Oct 21 doi: 10.3928/01913913-20101018-02. PMID: 20964274

Recent clinical studies

Etiology

To compare intralesional and oral propranolol for treating periorbital and eyelid capillary hemangiomas.
Mehta A, Bajaj MS, Pushker N, Chawla B, Pujari A, Grewal SS, Grewal SPS, Singh SR, Kishore A, Yadav NS
Indian J Ophthalmol 2019 Dec;67(12):1974-1980. doi: 10.4103/ijo.IJO_59_19. PMID: 31755431Free PMC Article
Leksell Radiosurgery for the 3 H Tumors: Hemangiomas, Hemangioblastomas, and Hemangiopericytomas.
Johnson S, Niranjan A, Kano H, Lunsford LD
Prog Neurol Surg 2019;34:223-231. Epub 2019 May 16 doi: 10.1159/000493068. PMID: 31096251
Hemangioblastoma of the optic nerve.
McGrath LA, Mudhar HS, Salvi SM
Surv Ophthalmol 2019 Mar-Apr;64(2):175-184. Epub 2018 Oct 13 doi: 10.1016/j.survophthal.2018.10.002. PMID: 30321570
Capillary hemangioma of the lids and orbit: an analysis of the clinical features and therapeutic results in 101 cases.
Haik BG, Jakobiec FA, Ellsworth RM, Jones IS
Ophthalmology 1979 May;86(5):760-92. doi: 10.1016/s0161-6420(79)35452-5. PMID: 545208
Ultrastructural comparison of capillary and cavernous hemangiomas of the orbit.
Iwamoto T, Jakobiec FA
Arch Ophthalmol 1979 Jun;97(6):1144-53. doi: 10.1001/archopht.1979.01020010598020. PMID: 444147

Diagnosis

Hemangioblastoma of the optic nerve.
McGrath LA, Mudhar HS, Salvi SM
Surv Ophthalmol 2019 Mar-Apr;64(2):175-184. Epub 2018 Oct 13 doi: 10.1016/j.survophthal.2018.10.002. PMID: 30321570
Recent Advances in Orbital Tumors--A Review of Publications from 2014-2016.
Honavar SG, Manjandavida FP
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):153-158. doi: 10.22608/APO.201736. PMID: 28399335
Congenital Eyelid Rhabdomyosarcoma.
Lee YC, Hsu YH, Yang SH, Huang TL
Ophthalmic Plast Reconstr Surg 2016 Sep-Oct;32(5):e104-6. doi: 10.1097/IOP.0000000000000290. PMID: 25216197
Capillary hemangioma (infantile periocular hemangioma).
Haik BG, Karcioglu ZA, Gordon RA, Pechous BP
Surv Ophthalmol 1994 Mar-Apr;38(5):399-426. doi: 10.1016/0039-6257(94)90172-4. PMID: 8009426
Vascular problems of the orbit.
Flanagan JC
Ophthalmology 1979 May;86(5):896-913. doi: 10.1016/s0161-6420(79)35442-2. PMID: 545218

Therapy

To compare intralesional and oral propranolol for treating periorbital and eyelid capillary hemangiomas.
Mehta A, Bajaj MS, Pushker N, Chawla B, Pujari A, Grewal SS, Grewal SPS, Singh SR, Kishore A, Yadav NS
Indian J Ophthalmol 2019 Dec;67(12):1974-1980. doi: 10.4103/ijo.IJO_59_19. PMID: 31755431Free PMC Article
β-blockers in the treatment of periocular infantile hemangioma.
Al-Haddad C, El Salloukh NA, El Moussawi Z
Curr Opin Ophthalmol 2019 Sep;30(5):319-325. doi: 10.1097/ICU.0000000000000591. PMID: 31394556
The Use of β-Blockers for the Treatment of Periocular Hemangiomas in Infants: A Report by the American Academy of Ophthalmology.
Hutchinson AK, Kraker RT, Pineles SL, VanderVeen DK, Wilson LB, Galvin JA, Lambert SR
Ophthalmology 2019 Jan;126(1):146-155. Epub 2018 Aug 1 doi: 10.1016/j.ophtha.2018.07.023. PMID: 30075202
Propranolol therapy for infantile hemangioma.
Gunturi N, Ramgopal S, Balagopal S, Scott JX
Indian Pediatr 2013 Mar;50(3):307-13. doi: 10.1007/s13312-013-0098-9. PMID: 23680605
New developments in the management of periocular capillary hemangioma in children.
Ni N, Wagner RS, Langer P, Guo S
J Pediatr Ophthalmol Strabismus 2011 Sep-Oct;48(5):269-76; quiz 268, 277. Epub 2010 Oct 21 doi: 10.3928/01913913-20101018-02. PMID: 20964274

Prognosis

Proptosis due to intraorbital space-occupying lesions in children.
Zahavi A, Luckman J, Ben-David GS, Toledano H, Michowiz S, Vardizer Y, Goldenberg-Cohen N
Graefes Arch Clin Exp Ophthalmol 2020 Nov;258(11):2541-2550. Epub 2020 Jul 16 doi: 10.1007/s00417-020-04840-3. PMID: 32676791
Optic Nerve Hemangioblastoma: Review.
Darbari S, Meena RK, Sawarkar D, Doddamani RS
World Neurosurg 2019 Aug;128:211-215. Epub 2019 May 1 doi: 10.1016/j.wneu.2019.04.224. PMID: 31054346
Risk factors for amblyopia in children with capillary hemangiomas of the eyelids and orbit.
Schwartz SR, Blei F, Ceisler E, Steele M, Furlan L, Kodsi S
J AAPOS 2006 Jun;10(3):262-8. doi: 10.1016/j.jaapos.2006.01.210. PMID: 16814181
Ophthalmological manifestations in VHL and NF 1: pathological and diagnostic implications.
Kreusel KM
Fam Cancer 2005;4(1):43-7. doi: 10.1007/s10689-004-1327-0. PMID: 15883709
Capillary hemangioma of the lids and orbit: an analysis of the clinical features and therapeutic results in 101 cases.
Haik BG, Jakobiec FA, Ellsworth RM, Jones IS
Ophthalmology 1979 May;86(5):760-92. doi: 10.1016/s0161-6420(79)35452-5. PMID: 545208

Clinical prediction guides

Clinical and Radiological Evaluation of Periocular Infantile Hemangioma Treated With Oral Propranolol: A Case Series.
Ginguerra MA, Saito O, Fernandes JBVD, Castro DS, Matayoshi S
Am J Ophthalmol 2018 Jan;185:48-55. Epub 2017 Nov 15 doi: 10.1016/j.ajo.2017.10.021. PMID: 29103963
Angiomyofibroma of the orbit: a hybrid of vascular leiomyoma and cavernous hemangioma.
Jakobiec FA, Zakka FR, Papakostas TD, Fay A
Ophthalmic Plast Reconstr Surg 2012 Nov-Dec;28(6):438-45. doi: 10.1097/IOP.0b013e318269693e. PMID: 23138203
Epithelioid hemangioma responsive to oral propranolol.
Moss HB, Sines DT, Blatt J, Dutton JJ, Proia AD
Ophthalmic Plast Reconstr Surg 2012 Jul-Aug;28(4):e88-90. doi: 10.1097/IOP.0b013e31823645f9. PMID: 22186982
Intralesional and sub-Tenon's infusion of corticosteroids for treatment of refractory periorbital and orbital capillary haemangioma.
Friling R, Axer-Siegel R, Ben-Amitai D, Goldenberg-Cohen N, Weinberger D, Snir M
Eye (Lond) 2009 Jun;23(6):1302-7. Epub 2008 Nov 7 doi: 10.1038/eye.2008.300. PMID: 18989344
Risk factors for amblyopia in children with capillary hemangiomas of the eyelids and orbit.
Schwartz SR, Blei F, Ceisler E, Steele M, Furlan L, Kodsi S
J AAPOS 2006 Jun;10(3):262-8. doi: 10.1016/j.jaapos.2006.01.210. PMID: 16814181

Recent systematic reviews

Treatment of periorbital infantile haemangiomas: a systematic literature review on propranolol or steroids.
Xu S, Jia R, Ge S, Lin M, Fan X
J Paediatr Child Health 2014 Apr;50(4):271-9. Epub 2013 Dec 23 doi: 10.1111/jpc.12464. PMID: 24754793
The use of propranolol in the management of periocular capillary haemangioma--a systematic review.
Spiteri Cornish K, Reddy AR
Eye (Lond) 2011 Oct;25(10):1277-83. Epub 2011 Jul 8 doi: 10.1038/eye.2011.164. PMID: 21738233Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...