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Untreated Childhood Acute Lymphoblastic Leukemia

MedGen UID:
852468
•Concept ID:
C0279091
•
Finding

Definition

A finding of acute lymphoblastic leukemia in childhood that has not been treated. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUntreated Childhood Acute Lymphoblastic Leukemia

Professional guidelines

PubMed

Two Cases of Veno-occlusive Disease/Sinusoidal Obstruction Syndrome After Thioguanine Treatment for Acute Lymphoblastic Leukemia.
Gruhn B, Brodt G, Mentzel HJ, Ernst J
J Pediatr Hematol Oncol 2022 Mar 1;44(2):e572-e575. doi: 10.1097/MPH.0000000000002172. PMID: 33885036Free PMC Article
Patient characteristics, treatment patterns, and mortality in elderly patients newly diagnosed with ALL.
Kim C, Molony JT, Chia VM, Kota VK, Katz AJ, Li S
Leuk Lymphoma 2019 Jun;60(6):1462-1468. Epub 2018 Dec 13 doi: 10.1080/10428194.2018.1538505. PMID: 30541363
Idarubicin in the treatment of acute leukemias. An overview of preclinical and clinical studies.
Carella AM, Berman E, Maraone MP, Ganzina F
Haematologica 1990 Mar-Apr;75(2):159-69. PMID: 2192943

Recent clinical studies

Etiology

In vitro cytotoxicity of mitoxantrone, daunorubicin and doxorubicin in untreated childhood acute leukemia.
Kaspers GL, Veerman AJ, Pieters R, van Zantwijk I, Klumper E, Hählen K, de Waal FC, van Wering ER
Leukemia 1994 Jan;8(1):24-9. PMID: 8289494

Diagnosis

In vitro cytotoxicity of mitoxantrone, daunorubicin and doxorubicin in untreated childhood acute leukemia.
Kaspers GL, Veerman AJ, Pieters R, van Zantwijk I, Klumper E, Hählen K, de Waal FC, van Wering ER
Leukemia 1994 Jan;8(1):24-9. PMID: 8289494

Prognosis

In vitro cytotoxicity of mitoxantrone, daunorubicin and doxorubicin in untreated childhood acute leukemia.
Kaspers GL, Veerman AJ, Pieters R, van Zantwijk I, Klumper E, Hählen K, de Waal FC, van Wering ER
Leukemia 1994 Jan;8(1):24-9. PMID: 8289494

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