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Palsy

MedGen UID:
854494
•Concept ID:
C3887651
•
Finding
Synonyms: palsy; Plegia; Plegias
 
Monarch Initiative: MONDO:0006496

Definition

Muscle weakness or paralysis of neurologic origin. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPalsy

Professional guidelines

PubMed

Interventions to improve physical function for children and young people with cerebral palsy: international clinical practice guideline.
Jackman M, Sakzewski L, Morgan C, Boyd RN, Brennan SE, Langdon K, Toovey RAM, Greaves S, Thorley M, Novak I
Dev Med Child Neurol 2022 May;64(5):536-549. Epub 2021 Sep 21 doi: 10.1111/dmcn.15055. PMID: 34549424
Progressive supranuclear palsy: diagnosis and management.
Rowe JB, Holland N, Rittman T
Pract Neurol 2021 Oct;21(5):376-383. Epub 2021 Jul 2 doi: 10.1136/practneurol-2020-002794. PMID: 34215700Free PMC Article
Early, Accurate Diagnosis and Early Intervention in Cerebral Palsy: Advances in Diagnosis and Treatment.
Novak I, Morgan C, Adde L, Blackman J, Boyd RN, Brunstrom-Hernandez J, Cioni G, Damiano D, Darrah J, Eliasson AC, de Vries LS, Einspieler C, Fahey M, Fehlings D, Ferriero DM, Fetters L, Fiori S, Forssberg H, Gordon AM, Greaves S, Guzzetta A, Hadders-Algra M, Harbourne R, Kakooza-Mwesige A, Karlsson P, Krumlinde-Sundholm L, Latal B, Loughran-Fowlds A, Maitre N, McIntyre S, Noritz G, Pennington L, Romeo DM, Shepherd R, Spittle AJ, Thornton M, Valentine J, Walker K, White R, Badawi N
JAMA Pediatr 2017 Sep 1;171(9):897-907. doi: 10.1001/jamapediatrics.2017.1689. PMID: 28715518Free PMC Article

Recent clinical studies

Etiology

Early Cerebral Palsy Detection and Intervention.
Mendoza-Sengco P, Lee Chicoine C, Vargus-Adams J
Pediatr Clin North Am 2023 Jun;70(3):385-398. Epub 2023 Mar 21 doi: 10.1016/j.pcl.2023.01.014. PMID: 37121632
A Critical Evaluation of Current Concepts in Cerebral Palsy.
Brandenburg JE, Fogarty MJ, Sieck GC
Physiology (Bethesda) 2019 May 1;34(3):216-229. doi: 10.1152/physiol.00054.2018. PMID: 30968751Free PMC Article
Early, Accurate Diagnosis and Early Intervention in Cerebral Palsy: Advances in Diagnosis and Treatment.
Novak I, Morgan C, Adde L, Blackman J, Boyd RN, Brunstrom-Hernandez J, Cioni G, Damiano D, Darrah J, Eliasson AC, de Vries LS, Einspieler C, Fahey M, Fehlings D, Ferriero DM, Fetters L, Fiori S, Forssberg H, Gordon AM, Greaves S, Guzzetta A, Hadders-Algra M, Harbourne R, Kakooza-Mwesige A, Karlsson P, Krumlinde-Sundholm L, Latal B, Loughran-Fowlds A, Maitre N, McIntyre S, Noritz G, Pennington L, Romeo DM, Shepherd R, Spittle AJ, Thornton M, Valentine J, Walker K, White R, Badawi N
JAMA Pediatr 2017 Sep 1;171(9):897-907. doi: 10.1001/jamapediatrics.2017.1689. PMID: 28715518Free PMC Article
Progressive supranuclear palsy.
Golbe LI
Semin Neurol 2014 Apr;34(2):151-9. Epub 2014 Jun 25 doi: 10.1055/s-0034-1381736. PMID: 24963674
Cerebral palsy.
Eicher PS, Batshaw ML
Pediatr Clin North Am 1993 Jun;40(3):537-51. doi: 10.1016/s0031-3955(16)38549-2. PMID: 8493064

Diagnosis

Progressive supranuclear palsy: diagnosis and management.
Rowe JB, Holland N, Rittman T
Pract Neurol 2021 Oct;21(5):376-383. Epub 2021 Jul 2 doi: 10.1136/practneurol-2020-002794. PMID: 34215700Free PMC Article
Cerebral Palsy: An Overview.
Vitrikas K, Dalton H, Breish D
Am Fam Physician 2020 Feb 15;101(4):213-220. PMID: 32053326
A Critical Evaluation of Current Concepts in Cerebral Palsy.
Brandenburg JE, Fogarty MJ, Sieck GC
Physiology (Bethesda) 2019 May 1;34(3):216-229. doi: 10.1152/physiol.00054.2018. PMID: 30968751Free PMC Article
Bell's Palsy.
Vakharia K, Vakharia K
Facial Plast Surg Clin North Am 2016 Feb;24(1):1-10. doi: 10.1016/j.fsc.2015.08.001. PMID: 26611696
Cerebral palsy.
Eicher PS, Batshaw ML
Pediatr Clin North Am 1993 Jun;40(3):537-51. doi: 10.1016/s0031-3955(16)38549-2. PMID: 8493064

Therapy

Four-Repeat Tauopathies: Current Management and Future Treatments.
VandeVrede L, Ljubenkov PA, Rojas JC, Welch AE, Boxer AL
Neurotherapeutics 2020 Oct;17(4):1563-1581. doi: 10.1007/s13311-020-00888-5. PMID: 32676851Free PMC Article
Progressive supranuclear palsy.
Boeve BF
Parkinsonism Relat Disord 2012 Jan;18 Suppl 1:S192-4. doi: 10.1016/S1353-8020(11)70060-8. PMID: 22166432
Managing Bell's palsy.
Drug Ther Bull 2006 Jul;44(7):49-53. doi: 10.1136/dtb.2006.44749. PMID: 16846138
Bell's palsy.
Salinas R
Clin Evid 2002 Jun;(7):1140-4. PMID: 12230732
Ethicology.
Bower E
Child Care Health Dev 1994 Jul-Aug;20(4):215-7. doi: 10.1111/j.1365-2214.1994.tb00384.x. PMID: 7955133

Prognosis

Incidence and morphology of secondary TDP-43 proteinopathies: Part 1.
Acewicz A, Stępień T, Felczak P, Tarka S, Wierzba-Bobrowicz T
Folia Neuropathol 2022;60(3):267-276. doi: 10.5114/fn.2022.120314. PMID: 36382478
The limits of small-for-gestational-age as a high-risk category.
Wilcox AJ, Cortese M, McConnaughey DR, Moster D, Basso O
Eur J Epidemiol 2021 Oct;36(10):985-991. Epub 2021 Oct 18 doi: 10.1007/s10654-021-00810-z. PMID: 34661814
Deep brain stimulation in cerebral palsy: Challenges and opportunities.
Koy A, Timmermann L
Eur J Paediatr Neurol 2017 Jan;21(1):118-121. Epub 2016 May 27 doi: 10.1016/j.ejpn.2016.05.015. PMID: 27289260
Fetal growth potential and pregnancy outcome.
Bukowski R
Semin Perinatol 2004 Feb;28(1):51-8. doi: 10.1053/j.semperi.2003.12.003. PMID: 15058902
Incidence and prevalence.
Pharoah PO
Arch Dis Child 1990 May;65(5):471. doi: 10.1136/adc.65.5.471. PMID: 2357081Free PMC Article

Clinical prediction guides

The general movement assessment in non-European low- and middle-income countries.
Tomantschger I, Herrero D, Einspieler C, Hamamura C, Voos MC, Marschik PB
Rev Saude Publica 2018 Feb 5;52:6. doi: 10.11606/S1518-8787.2018052000332. PMID: 29412374Free PMC Article
Advanced neuroimaging and its role in predicting neurodevelopmental outcomes in very preterm infants.
Parikh NA
Semin Perinatol 2016 Dec;40(8):530-541. Epub 2016 Nov 15 doi: 10.1053/j.semperi.2016.09.005. PMID: 27863706Free PMC Article
Prognostic significance of neurological signs in high-risk infants - a systematic review.
Hamer EG, Hadders-Algra M
Dev Med Child Neurol 2016 Mar;58 Suppl 4:53-60. doi: 10.1111/dmcn.13051. PMID: 27027608
Cerebral palsy--don't delay.
McIntyre S, Morgan C, Walker K, Novak I
Dev Disabil Res Rev 2011;17(2):114-29. doi: 10.1002/ddrr.1106. PMID: 23362031
Electronic fetal monitoring as a public health screening program: the arithmetic of failure.
Grimes DA, Peipert JF
Obstet Gynecol 2010 Dec;116(6):1397-1400. doi: 10.1097/AOG.0b013e3181fae39f. PMID: 21099609

Recent systematic reviews

The Effectiveness of Aquatic Therapy Based on the Halliwick Concept in Children with Cerebral Palsy: A Systematic Review.
Tapia C, Constanzo J, González V, Barría RM
Dev Neurorehabil 2023 Aug-Oct;26(6-7):371-376. Epub 2024 Jan 6 doi: 10.1080/17518423.2023.2259986. PMID: 37728374
Effects of Hippotherapy on Postural Control in Children With Cerebral Palsy: A Systematic Review.
Peia F, Veiga NC, Gomes AP, Santos BND, Marques NMS, Glória IPDS, Goulardins JB
Pediatr Phys Ther 2023 Apr 1;35(2):202-210. Epub 2023 Mar 3 doi: 10.1097/PEP.0000000000000999. PMID: 36867588
State of the Evidence Traffic Lights 2019: Systematic Review of Interventions for Preventing and Treating Children with Cerebral Palsy.
Novak I, Morgan C, Fahey M, Finch-Edmondson M, Galea C, Hines A, Langdon K, Namara MM, Paton MC, Popat H, Shore B, Khamis A, Stanton E, Finemore OP, Tricks A, Te Velde A, Dark L, Morton N, Badawi N
Curr Neurol Neurosci Rep 2020 Feb 21;20(2):3. doi: 10.1007/s11910-020-1022-z. PMID: 32086598Free PMC Article
Therapeutic effects of kinesio taping in children with cerebral palsy: a systematic review.
Ortiz Ramírez J, Pérez de la Cruz S
Arch Argent Pediatr 2017 Dec 1;115(6):e356-e361. doi: 10.5546/aap.2017.eng.e356. PMID: 29087112
Occupational therapy for children with cerebral palsy: a systematic review.
Steultjens EM, Dekker J, Bouter LM, van de Nes JC, Lambregts BL, van den Ende CH
Clin Rehabil 2004 Feb;18(1):1-14. doi: 10.1191/0269215504cr697oa. PMID: 14763715

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    Clinical resources

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