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Effusion

MedGen UID:
8557
Concept ID:
C0013687
Pathologic Function
Synonym: Free fluid
SNOMED CT: Effusion (41699000); Free fluid (41699000)

Definition

A collection of fluid in a body cavity, which may be the result of a non-neoplastic disorder (e.g. heart failure) or a tumor (e.g. carcinoma of the lung). [from NCI]

Professional guidelines

PubMed

Agrawal A, Chaddha U, Kaul V, Desai A, Gillaspie E, Maldonado F
Chest 2022 Dec;162(6):1402-1412. Epub 2022 Jun 20 doi: 10.1016/j.chest.2022.06.012. PMID: 35738344
Jany B, Welte T
Dtsch Arztebl Int 2019 May 24;116(21):377-386. doi: 10.3238/arztebl.2019.0377. PMID: 31315808Free PMC Article
Jeong SH, Lee HS
Intervirology 2010;53(1):15-9. Epub 2010 Jan 5 doi: 10.1159/000252779. PMID: 20068336

Recent clinical studies

Etiology

Sorino C, Mondoni M, Lococo F, Marchetti G, Feller-Kopman D
Respir Med 2022 Jan;191:106706. Epub 2021 Nov 26 doi: 10.1016/j.rmed.2021.106706. PMID: 34896966
Paiardi S, Pellegrino M, Cannata F, Bocciolone M, Voza A
Am J Emerg Med 2018 Mar;36(3):524.e1-524.e6. Epub 2017 Nov 21 doi: 10.1016/j.ajem.2017.11.047. PMID: 29169889
Vakamudi S, Ho N, Cremer PC
Prog Cardiovasc Dis 2017 Jan-Feb;59(4):380-388. Epub 2017 Jan 4 doi: 10.1016/j.pcad.2016.12.009. PMID: 28062268
Atkinson H, Wallis S, Coatesworth AP
Postgrad Med 2015 May;127(4):381-5. doi: 10.1080/00325481.2015.1028317. PMID: 25913597
Ferreiro L, San José ME, Valdés L
Arch Bronconeumol 2015 Dec;51(12):637-46. Epub 2015 Mar 26 doi: 10.1016/j.arbres.2015.01.009. PMID: 25820035

Diagnosis

Ferreiro L, Toubes ME, San José ME, Suárez-Antelo J, Golpe A, Valdés L
Expert Rev Respir Med 2020 Jan;14(1):51-66. Epub 2019 Nov 5 doi: 10.1080/17476348.2020.1684266. PMID: 31640432
Jany B, Welte T
Dtsch Arztebl Int 2019 May 24;116(21):377-386. doi: 10.3238/arztebl.2019.0377. PMID: 31315808Free PMC Article
Beaudoin S, Gonzalez AV
CMAJ 2018 Mar 12;190(10):E291-E295. doi: 10.1503/cmaj.170420. PMID: 29530870Free PMC Article
Ferreiro L, San José ME, Valdés L
Arch Bronconeumol 2015 Dec;51(12):637-46. Epub 2015 Mar 26 doi: 10.1016/j.arbres.2015.01.009. PMID: 25820035
Porcel JM, Light RW
Am Fam Physician 2006 Apr 1;73(7):1211-20. PMID: 16623208

Therapy

Hoberman A, Preciado D, Paradise JL, Chi DH, Haralam M, Block SL, Kearney DH, Bhatnagar S, Muñiz Pujalt GB, Shope TR, Martin JM, Felten DE, Kurs-Lasky M, Liu H, Yahner K, Jeong JH, Cohen NL, Czervionke B, Nagg JP, Dohar JE, Shaikh N
N Engl J Med 2021 May 13;384(19):1789-1799. doi: 10.1056/NEJMoa2027278. PMID: 33979487Free PMC Article
Feller-Kopman DJ, Reddy CB, DeCamp MM, Diekemper RL, Gould MK, Henry T, Iyer NP, Lee YCG, Lewis SZ, Maskell NA, Rahman NM, Sterman DH, Wahidi MM, Balekian AA
Am J Respir Crit Care Med 2018 Oct 1;198(7):839-849. doi: 10.1164/rccm.201807-1415ST. PMID: 30272503
Llewellyn A, Norman G, Harden M, Coatesworth A, Kimberling D, Schilder A, McDaid C
Health Technol Assess 2014 Jul;18(46):1-180, v-vi. doi: 10.3310/hta18460. PMID: 25029951Free PMC Article
Rahman NM, Maskell NA, West A, Teoh R, Arnold A, Mackinlay C, Peckham D, Davies CW, Ali N, Kinnear W, Bentley A, Kahan BC, Wrightson JM, Davies HE, Hooper CE, Lee YC, Hedley EL, Crosthwaite N, Choo L, Helm EJ, Gleeson FV, Nunn AJ, Davies RJ
N Engl J Med 2011 Aug 11;365(6):518-26. doi: 10.1056/NEJMoa1012740. PMID: 21830966
McGrath EE, Anderson PB
Am J Crit Care 2011 Mar;20(2):119-27; quiz 128. doi: 10.4037/ajcc2011685. PMID: 21362716

Prognosis

Zeng T, An J, Wu Y, Hu X, An N, Gao L, Wan C, Liu L, Shen Y
Ann Med 2023;55(2):2285909. Epub 2023 Nov 27 doi: 10.1080/07853890.2023.2285909. PMID: 38010411Free PMC Article
Grønberg BH, Killingberg KT, Fløtten Ø, Brustugun OT, Hornslien K, Madebo T, Langer SW, Schytte T, Nyman J, Risum S, Tsakonas G, Engleson J, Halvorsen TO
Lancet Oncol 2021 Mar;22(3):321-331. doi: 10.1016/S1470-2045(20)30742-7. PMID: 33662285
Yan L, Rohra P, Cheng L, Gattuso P
Acta Cytol 2020;64(3):241-247. Epub 2019 Jul 2 doi: 10.1159/000500973. PMID: 31266012
Dedhia K, Graham E, Park A
Clin Perinatol 2018 Dec;45(4):629-643. Epub 2018 Sep 24 doi: 10.1016/j.clp.2018.07.004. PMID: 30396409
Erickson B, Dhaliwal G, Henderson MC, Amsterdam E, Rencic J
J Gen Intern Med 2011 Oct;26(10):1204-8. Epub 2011 Jul 15 doi: 10.1007/s11606-011-1785-7. PMID: 21761239Free PMC Article

Clinical prediction guides

Sinnaeve PR, Adriaenssens T
Trends Cardiovasc Med 2019 Oct;29(7):375-383. Epub 2018 Nov 20 doi: 10.1016/j.tcm.2018.10.016. PMID: 30482483
Picano E, Scali MC, Ciampi Q, Lichtenstein D
JACC Cardiovasc Imaging 2018 Nov;11(11):1692-1705. doi: 10.1016/j.jcmg.2018.06.023. PMID: 30409330
Piccolo CL, Ianniello S, Trinci M, Galluzzo M, Tonerini M, Zeccolini M, Guglielmi G, Miele V
Radiol Med 2017 Nov;122(11):850-865. Epub 2017 Jul 4 doi: 10.1007/s11547-017-0783-1. PMID: 28674910
Oo WM, Bo MT
J Clin Rheumatol 2016 Sep;22(6):324-9. doi: 10.1097/RHU.0000000000000436. PMID: 27556241
Zraier S, Haouache H, Dhonneur G
Ann Fr Anesth Reanim 2014 Jul-Aug;33(7-8):453-6. Epub 2014 Aug 29 doi: 10.1016/j.annfar.2014.07.743. PMID: 25168302

Recent systematic reviews

Yu J, Tang J, Chen M, Ren Q, He J, Tang M, Zhang X, Liu Z, Ding H
J Clin Neurosci 2023 Jan;107:23-33. Epub 2022 Nov 30 doi: 10.1016/j.jocn.2022.11.010. PMID: 36462413
Dainese P, Wyngaert KV, De Mits S, Wittoek R, Van Ginckel A, Calders P
Osteoarthritis Cartilage 2022 Apr;30(4):516-534. Epub 2021 Dec 27 doi: 10.1016/j.joca.2021.12.003. PMID: 34968719
Tsheten T, Clements ACA, Gray DJ, Adhikary RK, Furuya-Kanamori L, Wangdi K
Infect Dis Poverty 2021 Oct 9;10(1):123. doi: 10.1186/s40249-021-00908-2. PMID: 34627388Free PMC Article
Feller-Kopman DJ, Reddy CB, DeCamp MM, Diekemper RL, Gould MK, Henry T, Iyer NP, Lee YCG, Lewis SZ, Maskell NA, Rahman NM, Sterman DH, Wahidi MM, Balekian AA
Am J Respir Crit Care Med 2018 Oct 1;198(7):839-849. doi: 10.1164/rccm.201807-1415ST. PMID: 30272503
Imazio M, Gaita F, LeWinter M
JAMA 2015 Oct 13;314(14):1498-506. doi: 10.1001/jama.2015.12763. PMID: 26461998

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