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Hypercoiled Umbilical Cord

MedGen UID:
858426
•Concept ID:
C3898832
•
Finding

Definition

Umbilical cord with apparent increased helical coiling of the arteries around the vein. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHypercoiled Umbilical Cord

Professional guidelines

PubMed

Ultrasound diagnosis and management of umbilical cord abnormalities.
Hasegawa J, Matsuoka R, Ichizuka K, Sekizawa A, Okai T
Taiwan J Obstet Gynecol 2009 Mar;48(1):23-7. doi: 10.1016/S1028-4559(09)60031-0. PMID: 19346188

Recent clinical studies

Etiology

Comparison of the Autopsy and Placental Findings in Second vs Third Trimester Stillbirth.
Manjee K, Price E, Ernst LM
Pediatr Dev Pathol 2023 Jul-Aug;26(4):345-351. Epub 2023 Apr 21 doi: 10.1177/10935266231165854. PMID: 37082921
Cesarean section per se is not a risk factor for non-anatomical placenta creta.
Stanek J
Int J Gynaecol Obstet 2023 Mar;160(3):969-977. Epub 2022 Sep 5 doi: 10.1002/ijgo.14415. PMID: 35993138
Fetal Vascular Malperfusion Due To Long and Hypercoiled Umbilical Cords Resulting in Recurrent Second Trimester Pregnancy Loss: A Case Series and Literature Review.
Slack JC, Boyd TK
Pediatr Dev Pathol 2021 Jan-Feb;24(1):12-18. Epub 2020 Sep 28 doi: 10.1177/1093526620962061. PMID: 32986509
Placental examination in nonmacerated stillbirth versus neonatal mortality.
Stanek J
J Perinat Med 2018 Apr 25;46(3):323-331. doi: 10.1515/jpm-2017-0198. PMID: 28915123
Atypical hemodynamic pattern in fetuses with hypercoiled umbilical cord and growth restriction.
Clerici G, Antonelli C, Rizzo G, Kanninen TT, Di Renzo GC
J Matern Fetal Neonatal Med 2013 Apr;26(6):558-62. Epub 2012 Nov 23 doi: 10.3109/14767058.2012.741153. PMID: 23134215

Diagnosis

Clinical Significance of the Large Fetal Vessel Lesions in Placental Fetal Vascular Malperfusion.
Stanek J
Lab Invest 2024 Jul;104(7):102089. Epub 2024 May 27 doi: 10.1016/j.labinv.2024.102089. PMID: 38810837
The impact of polycystic ovary syndrome on placental histopathology patterns in in-vitro fertilization singleton live births.
Hochberg A, Mills G, Volodarsky-Perel A, Nu TNT, Machado-Gedeon A, Cui Y, Shaul J, Dahan MH
Placenta 2023 Aug;139:12-18. Epub 2023 Jun 3 doi: 10.1016/j.placenta.2023.05.015. PMID: 37290292
Cesarean section per se is not a risk factor for non-anatomical placenta creta.
Stanek J
Int J Gynaecol Obstet 2023 Mar;160(3):969-977. Epub 2022 Sep 5 doi: 10.1002/ijgo.14415. PMID: 35993138

Therapy

The impact of polycystic ovary syndrome on placental histopathology patterns in in-vitro fertilization singleton live births.
Hochberg A, Mills G, Volodarsky-Perel A, Nu TNT, Machado-Gedeon A, Cui Y, Shaul J, Dahan MH
Placenta 2023 Aug;139:12-18. Epub 2023 Jun 3 doi: 10.1016/j.placenta.2023.05.015. PMID: 37290292
Cesarean section per se is not a risk factor for non-anatomical placenta creta.
Stanek J
Int J Gynaecol Obstet 2023 Mar;160(3):969-977. Epub 2022 Sep 5 doi: 10.1002/ijgo.14415. PMID: 35993138
An experience of second-trimester anhydramnios salvaged by single amnioinfusion.
Io S, Kondoh E, Chigusa Y, Tani H, Hamanishi J, Konishi I
J Med Ultrason (2001) 2018 Jul;45(3):525-527. Epub 2017 Nov 20 doi: 10.1007/s10396-017-0842-1. PMID: 29159576

Prognosis

Clinical Significance of the Large Fetal Vessel Lesions in Placental Fetal Vascular Malperfusion.
Stanek J
Lab Invest 2024 Jul;104(7):102089. Epub 2024 May 27 doi: 10.1016/j.labinv.2024.102089. PMID: 38810837
Cesarean section per se is not a risk factor for non-anatomical placenta creta.
Stanek J
Int J Gynaecol Obstet 2023 Mar;160(3):969-977. Epub 2022 Sep 5 doi: 10.1002/ijgo.14415. PMID: 35993138
An experience of second-trimester anhydramnios salvaged by single amnioinfusion.
Io S, Kondoh E, Chigusa Y, Tani H, Hamanishi J, Konishi I
J Med Ultrason (2001) 2018 Jul;45(3):525-527. Epub 2017 Nov 20 doi: 10.1007/s10396-017-0842-1. PMID: 29159576
Placental examination in nonmacerated stillbirth versus neonatal mortality.
Stanek J
J Perinat Med 2018 Apr 25;46(3):323-331. doi: 10.1515/jpm-2017-0198. PMID: 28915123
Abnormal ductus venosus blood flow: a clue to umbilical cord complication.
Bäz E, Zikulnig L, Hackelöer BJ, Hecher K
Ultrasound Obstet Gynecol 1999 Mar;13(3):204-6. doi: 10.1046/j.1469-0705.1999.13030204.x. PMID: 10204214

Clinical prediction guides

Cesarean section per se is not a risk factor for non-anatomical placenta creta.
Stanek J
Int J Gynaecol Obstet 2023 Mar;160(3):969-977. Epub 2022 Sep 5 doi: 10.1002/ijgo.14415. PMID: 35993138
Atypical hemodynamic pattern in fetuses with hypercoiled umbilical cord and growth restriction.
Clerici G, Antonelli C, Rizzo G, Kanninen TT, Di Renzo GC
J Matern Fetal Neonatal Med 2013 Apr;26(6):558-62. Epub 2012 Nov 23 doi: 10.3109/14767058.2012.741153. PMID: 23134215
Characteristics of blood flow in intrauterine growth-restricted fetuses with hypercoiled cord.
Nishio J, Nakai Y, Mine M, Imanaka M, Ogita S
Ultrasound Obstet Gynecol 1999 Mar;13(3):171-5. doi: 10.1046/j.1469-0705.1999.13030171.x. PMID: 10204207

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