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Familial Idiopathic Tall Stature

MedGen UID:
858750
•Concept ID:
C3899156
•
Disease or Syndrome

Definition

Idiopathic tall stature in a child when either one or both parents is tall in stature. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFamilial Idiopathic Tall Stature

Professional guidelines

PubMed

Diagnostic Work-up and Follow-up in Children with Tall Stature: A Simplified Algorithm for Clinical Practice.
Stalman SE, Pons A, Wit JM, Kamp GA, Plötz FB
J Clin Res Pediatr Endocrinol 2015 Dec;7(4):260-7. doi: 10.4274/jcrpe.2220. PMID: 26777036Free PMC Article

Recent clinical studies

Etiology

Abnormal Auditory Mismatch Fields in Children and Adolescents with 47,XYY Syndrome.
Matsuzaki J, Bloy L, Blaskey L, Miller J, Kuschner ES, Ku M, Dipiero M, Airey M, Edgar JC, Embick D, Ross JL, Roberts TPL
Dev Neurosci 2019;41(1-2):123-131. Epub 2019 Jul 5 doi: 10.1159/000500799. PMID: 31280271Free PMC Article
Maternal Height and Preterm Birth: A Study on 192,432 Swedish Women.
Derraik JG, Lundgren M, Cutfield WS, Ahlsson F
PLoS One 2016;11(4):e0154304. Epub 2016 Apr 21 doi: 10.1371/journal.pone.0154304. PMID: 27100080Free PMC Article
Diagnostic Work-up and Follow-up in Children with Tall Stature: A Simplified Algorithm for Clinical Practice.
Stalman SE, Pons A, Wit JM, Kamp GA, Plötz FB
J Clin Res Pediatr Endocrinol 2015 Dec;7(4):260-7. doi: 10.4274/jcrpe.2220. PMID: 26777036Free PMC Article
Somatic overgrowth predisposes to seizures in autism spectrum disorders.
Valvo G, Baldini S, Brachini F, Apicella F, Cosenza A, Ferrari AR, Guerrini R, Muratori F, Romano MF, Santorelli FM, Tancredi R, Sicca F
PLoS One 2013;8(9):e75015. Epub 2013 Sep 23 doi: 10.1371/journal.pone.0075015. PMID: 24086423Free PMC Article
Bayley-Pinneau, Roche-Wainer-Thissen, and Tanner height predictions in normal children and in patients with various pathologic conditions.
Zachmann M, Sobradillo B, Frank M, Frisch H, Prader A
J Pediatr 1978 Nov;93(5):749-55. doi: 10.1016/s0022-3476(78)81071-3. PMID: 712475

Diagnosis

NPR2 gene variants in familial short stature: a single-center study.
Yuan K, Chen J, Chen Q, Chen H, Zhu J, Fang Y, Wang C
J Pediatr Endocrinol Metab 2022 Feb 23;35(2):185-190. Epub 2021 Sep 27 doi: 10.1515/jpem-2021-0332. PMID: 34565054
Abnormal Auditory Mismatch Fields in Children and Adolescents with 47,XYY Syndrome.
Matsuzaki J, Bloy L, Blaskey L, Miller J, Kuschner ES, Ku M, Dipiero M, Airey M, Edgar JC, Embick D, Ross JL, Roberts TPL
Dev Neurosci 2019;41(1-2):123-131. Epub 2019 Jul 5 doi: 10.1159/000500799. PMID: 31280271Free PMC Article
Diagnostic Work-up and Follow-up in Children with Tall Stature: A Simplified Algorithm for Clinical Practice.
Stalman SE, Pons A, Wit JM, Kamp GA, Plötz FB
J Clin Res Pediatr Endocrinol 2015 Dec;7(4):260-7. doi: 10.4274/jcrpe.2220. PMID: 26777036Free PMC Article
Evaluation of Short and Tall Stature in Children.
Barstow C, Rerucha C
Am Fam Physician 2015 Jul 1;92(1):43-50. PMID: 26132126
Somatic overgrowth predisposes to seizures in autism spectrum disorders.
Valvo G, Baldini S, Brachini F, Apicella F, Cosenza A, Ferrari AR, Guerrini R, Muratori F, Romano MF, Santorelli FM, Tancredi R, Sicca F
PLoS One 2013;8(9):e75015. Epub 2013 Sep 23 doi: 10.1371/journal.pone.0075015. PMID: 24086423Free PMC Article

Therapy

NPR2 gene variants in familial short stature: a single-center study.
Yuan K, Chen J, Chen Q, Chen H, Zhu J, Fang Y, Wang C
J Pediatr Endocrinol Metab 2022 Feb 23;35(2):185-190. Epub 2021 Sep 27 doi: 10.1515/jpem-2021-0332. PMID: 34565054
When do short children realize they are short? Prepubertal short children's perception of height during 24 months of catch-up growth hormone treatment.
Chaplin JE, Kriström B, Jonsson B, Halldin Stenlid M, Aronson AS, Dahlgren J, Albertsson-Wikland K
Horm Res Paediatr 2012;77(4):241-9. Epub 2012 Apr 19 doi: 10.1159/000337975. PMID: 22516981

Prognosis

Diagnostic Work-up and Follow-up in Children with Tall Stature: A Simplified Algorithm for Clinical Practice.
Stalman SE, Pons A, Wit JM, Kamp GA, Plötz FB
J Clin Res Pediatr Endocrinol 2015 Dec;7(4):260-7. doi: 10.4274/jcrpe.2220. PMID: 26777036Free PMC Article
Bayley-Pinneau, Roche-Wainer-Thissen, and Tanner height predictions in normal children and in patients with various pathologic conditions.
Zachmann M, Sobradillo B, Frank M, Frisch H, Prader A
J Pediatr 1978 Nov;93(5):749-55. doi: 10.1016/s0022-3476(78)81071-3. PMID: 712475

Clinical prediction guides

Abnormal Auditory Mismatch Fields in Children and Adolescents with 47,XYY Syndrome.
Matsuzaki J, Bloy L, Blaskey L, Miller J, Kuschner ES, Ku M, Dipiero M, Airey M, Edgar JC, Embick D, Ross JL, Roberts TPL
Dev Neurosci 2019;41(1-2):123-131. Epub 2019 Jul 5 doi: 10.1159/000500799. PMID: 31280271Free PMC Article
Diagnostic Work-up and Follow-up in Children with Tall Stature: A Simplified Algorithm for Clinical Practice.
Stalman SE, Pons A, Wit JM, Kamp GA, Plötz FB
J Clin Res Pediatr Endocrinol 2015 Dec;7(4):260-7. doi: 10.4274/jcrpe.2220. PMID: 26777036Free PMC Article
Heterozygous mutations in natriuretic peptide receptor-B (NPR2) gene as a cause of short stature.
Wang SR, Jacobsen CM, Carmichael H, Edmund AB, Robinson JW, Olney RC, Miller TC, Moon JE, Mericq V, Potter LR, Warman ML, Hirschhorn JN, Dauber A
Hum Mutat 2015 Apr;36(4):474-81. Epub 2015 Mar 16 doi: 10.1002/humu.22773. PMID: 25703509Free PMC Article
Hypogonadotropic hypogonadism due to GnRH receptor mutation in a sibling.
Fichna P, Fichna M, Zurawek M, Nowak J
Endokrynol Pol 2011;62(3):264-7. PMID: 21717411
Bayley-Pinneau, Roche-Wainer-Thissen, and Tanner height predictions in normal children and in patients with various pathologic conditions.
Zachmann M, Sobradillo B, Frank M, Frisch H, Prader A
J Pediatr 1978 Nov;93(5):749-55. doi: 10.1016/s0022-3476(78)81071-3. PMID: 712475

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