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Childhood gonadal germ cell tumor

MedGen UID:
859251
Concept ID:
C3899657
Neoplastic Process
Synonym: Gonadal germ cell tumors
 
Monarch Initiative: MONDO:0020577

Definition

A germ cell tumor that arises from the testis or ovary and occurs during childhood. [from NCI]

Professional guidelines

PubMed

Rosimont M, Kariyawasam D, Samara-Boustani D, Giani E, Beltrand J, Bolle S, Fresneau B, Puget S, Sainte-Rose C, Alapetite C, Pinto G, Touraine P, Piketty ML, Brabant S, Abbou S, Aerts I, Beccaria K, Bourgeois M, Roujeau T, Blauwblomme T, Rocco FD, Thalassinos C, Rigaud C, James S, Busiah K, Simon A, Bourdeaut F, Lemelle L, Guerrini-Rousseau L, Orbach D, Doz F, Dufour C, Grill J, Polak M, Briceño LG
J Clin Endocrinol Metab 2023 Aug 18;108(9):e823-e831. doi: 10.1210/clinem/dgad097. PMID: 36810692
Kanakatti Shankar R, Dowlut-McElroy T, Dauber A, Gomez-Lobo V
J Clin Endocrinol Metab 2022 Jan 18;107(2):309-323. doi: 10.1210/clinem/dgab687. PMID: 34537849Free PMC Article
Göbel U, Calaminus G, Schneider DT, Schmidt P, Haas RJ; MAKEI and MAHO Study Groups of the German Society of Pediatric Oncology and Hematology, and the SIOP CNS GCT Study Group
Onkologie 2002 Feb;25(1):14-22. doi: 10.1159/000055197. PMID: 11893878

Recent clinical studies

Etiology

Rosimont M, Kariyawasam D, Samara-Boustani D, Giani E, Beltrand J, Bolle S, Fresneau B, Puget S, Sainte-Rose C, Alapetite C, Pinto G, Touraine P, Piketty ML, Brabant S, Abbou S, Aerts I, Beccaria K, Bourgeois M, Roujeau T, Blauwblomme T, Rocco FD, Thalassinos C, Rigaud C, James S, Busiah K, Simon A, Bourdeaut F, Lemelle L, Guerrini-Rousseau L, Orbach D, Doz F, Dufour C, Grill J, Polak M, Briceño LG
J Clin Endocrinol Metab 2023 Aug 18;108(9):e823-e831. doi: 10.1210/clinem/dgad097. PMID: 36810692
Rosti G, Secondino S, Necchi A, Fornarini G, Pedrazzoli P
Semin Oncol 2019 Apr;46(2):107-111. Epub 2019 Apr 24 doi: 10.1053/j.seminoncol.2019.04.001. PMID: 31076171
Boussios S, Zarkavelis G, Seraj E, Zerdes I, Tatsi K, Pentheroudakis G
Anticancer Res 2016 Oct;36(10):5031-5042. doi: 10.21873/anticanres.11072. PMID: 27798862
Al-Hussain T, Bakshi N, Akhtar M
Adv Anat Pathol 2015 May;22(3):202-12. doi: 10.1097/PAP.0000000000000066. PMID: 25844678
Hughes IA, Werner R, Bunch T, Hiort O
Semin Reprod Med 2012 Oct;30(5):432-42. Epub 2012 Oct 8 doi: 10.1055/s-0032-1324728. PMID: 23044881

Diagnosis

Kanakatti Shankar R, Dowlut-McElroy T, Dauber A, Gomez-Lobo V
J Clin Endocrinol Metab 2022 Jan 18;107(2):309-323. doi: 10.1210/clinem/dgab687. PMID: 34537849Free PMC Article
Boussios S, Zarkavelis G, Seraj E, Zerdes I, Tatsi K, Pentheroudakis G
Anticancer Res 2016 Oct;36(10):5031-5042. doi: 10.21873/anticanres.11072. PMID: 27798862
Hughes IA, Werner R, Bunch T, Hiort O
Semin Reprod Med 2012 Oct;30(5):432-42. Epub 2012 Oct 8 doi: 10.1055/s-0032-1324728. PMID: 23044881
Azizkhan RG, Caty MG
Curr Opin Pediatr 1996 Jun;8(3):287-92. doi: 10.1097/00008480-199606000-00018. PMID: 8814409
Pearson JC
Urology 1981 Feb;17(2):119-25. doi: 10.1016/0090-4295(81)90217-x. PMID: 6781115

Therapy

Ramanathan S, Prasad M, Vora T, Parambil BC, Kembhavi S, Ramadwar M, Khanna N, Laskar S, Kurkure P, Qureshi S, Banavali S, Chinnaswamy G
Pediatr Blood Cancer 2022 Jul;69(7):e29765. Epub 2022 May 13 doi: 10.1002/pbc.29765. PMID: 35561025
Jain R, Menon P, Bansal D, Kakkar N, Radhika S, Rao KLN, Trehan A
Pediatr Hematol Oncol 2022 Apr;39(3):267-277. Epub 2021 Oct 19 doi: 10.1080/08880018.2021.1980164. PMID: 34665989
Aslan IR, Cheung CC
J Pediatr Rehabil Med 2014;7(4):281-94. doi: 10.3233/PRM-140299. PMID: 25547881
Hudson MM
Obstet Gynecol 2010 Nov;116(5):1171-83. doi: 10.1097/AOG.0b013e3181f87c4b. PMID: 20966703Free PMC Article
Göbel U, Calaminus G, Schneider DT, Schmidt P, Haas RJ; MAKEI and MAHO Study Groups of the German Society of Pediatric Oncology and Hematology, and the SIOP CNS GCT Study Group
Onkologie 2002 Feb;25(1):14-22. doi: 10.1159/000055197. PMID: 11893878

Prognosis

Kanakatti Shankar R, Dowlut-McElroy T, Dauber A, Gomez-Lobo V
J Clin Endocrinol Metab 2022 Jan 18;107(2):309-323. doi: 10.1210/clinem/dgab687. PMID: 34537849Free PMC Article
Rosti G, Secondino S, Necchi A, Fornarini G, Pedrazzoli P
Semin Oncol 2019 Apr;46(2):107-111. Epub 2019 Apr 24 doi: 10.1053/j.seminoncol.2019.04.001. PMID: 31076171
Boussios S, Zarkavelis G, Seraj E, Zerdes I, Tatsi K, Pentheroudakis G
Anticancer Res 2016 Oct;36(10):5031-5042. doi: 10.21873/anticanres.11072. PMID: 27798862
Abacı A, Çatlı G, Berberoğlu M
J Pediatr Endocrinol Metab 2015 Sep;28(9-10):1019-27. doi: 10.1515/jpem-2014-0522. PMID: 25879315
Aslan IR, Cheung CC
J Pediatr Rehabil Med 2014;7(4):281-94. doi: 10.3233/PRM-140299. PMID: 25547881

Clinical prediction guides

Schraw JM, Sok P, Desrosiers TA, Janitz AE, Langlois PH, Canfield MA, Frazier AL, Plon SE, Lupo PJ, Poynter JN
Cancer 2023 Oct 15;129(20):3300-3308. Epub 2023 Jun 27 doi: 10.1002/cncr.34906. PMID: 37366624Free PMC Article
Jain R, Menon P, Bansal D, Kakkar N, Radhika S, Rao KLN, Trehan A
Pediatr Hematol Oncol 2022 Apr;39(3):267-277. Epub 2021 Oct 19 doi: 10.1080/08880018.2021.1980164. PMID: 34665989
Kanakatti Shankar R, Dowlut-McElroy T, Dauber A, Gomez-Lobo V
J Clin Endocrinol Metab 2022 Jan 18;107(2):309-323. doi: 10.1210/clinem/dgab687. PMID: 34537849Free PMC Article
Abacı A, Çatlı G, Berberoğlu M
J Pediatr Endocrinol Metab 2015 Sep;28(9-10):1019-27. doi: 10.1515/jpem-2014-0522. PMID: 25879315
Azizkhan RG, Caty MG
Curr Opin Pediatr 1996 Jun;8(3):287-92. doi: 10.1097/00008480-199606000-00018. PMID: 8814409

Recent systematic reviews

Kanakatti Shankar R, Dowlut-McElroy T, Dauber A, Gomez-Lobo V
J Clin Endocrinol Metab 2022 Jan 18;107(2):309-323. doi: 10.1210/clinem/dgab687. PMID: 34537849Free PMC Article
Braam KI, Overbeek A, Kaspers GJ, Ronckers CM, Schouten-van Meeteren AY, Van Dulmen-Den Broeder E, Veening MA
Pediatr Blood Cancer 2012 May;58(5):665-74. Epub 2012 Jan 9 doi: 10.1002/pbc.24023. PMID: 22232079

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