U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal emotion

MedGen UID:
866603
•Concept ID:
C4020949
•
Mental or Behavioral Dysfunction
Synonyms: Abnormal emotion processing; Abnormal emotion/affect behavior; Abnormal emotion/affect behaviour; Abnormal mood/emotion/affect; Abnormal mood/emotion/affect/thought; Emotion dysregulation
 
HPO: HP:0100851

Definition

Abnormalities in the intensity, frequency, or duration of emotional experiences. [from HPO]

Professional guidelines

PubMed

Shame in the treatment of patients with psychogenic nonepileptic seizures: The elephant in the room.
Myers L, Gray C, Roberts N, Levita L, Reuber M
Seizure 2022 Jan;94:176-182. Epub 2021 Oct 29 doi: 10.1016/j.seizure.2021.10.018. PMID: 34876339

Recent clinical studies

Etiology

Task-related brain activation associated with violence in patients with schizophrenia: A meta-analysis.
Wang YM, Zhang YY, Wang Y, Cao Q, Zhang M
Asian J Psychiatr 2024 Jul;97:104080. Epub 2024 May 18 doi: 10.1016/j.ajp.2024.104080. PMID: 38788320
Neural basis of positive and negative emotion regulation in remitted depression.
van Kleef RS, Marsman JC, van Valen E, Bockting CLH, Aleman A, van Tol MJ
Neuroimage Clin 2022;34:102988. Epub 2022 Mar 11 doi: 10.1016/j.nicl.2022.102988. PMID: 35298997Free PMC Article
Inflammatory state and autism-like behavioral phenotype of offspring induced by maternal exposure to low-dose chemical mixtures during pregnancy in mice.
Song L, Wen W, Liu J, Jin X, Yang J
Zhejiang Da Xue Xue Bao Yi Xue Ban 2021 Jun 25;50(3):279-289. doi: 10.3724/zdxbyxb-2021-0182. PMID: 34402257Free PMC Article
The broken trust and cooperation in borderline personality disorder.
Seres I, Unoka Z, Kéri S
Neuroreport 2009 Mar 4;20(4):388-92. doi: 10.1097/WNR.0b013e328324eb4d. PMID: 19218873
Impaired fronto-temporal processing of emotion in schizophrenia.
Bediou B, Hénaff MA, Bertrand O, Brunelin J, d'Amato T, Saoud M, Krolak-Salmon P
Neurophysiol Clin 2007 Apr-May;37(2):77-87. Epub 2007 Apr 13 doi: 10.1016/j.neucli.2007.04.001. PMID: 17540290

Diagnosis

Quantifying abnormal emotion processing: A novel computational assessment method and application in schizophrenia.
Bradley ER, Portanova J, Woolley JD, Buck B, Painter IS, Hankin M, Xu W, Cohen T
Psychiatry Res 2024 Jun;336:115893. Epub 2024 Apr 4 doi: 10.1016/j.psychres.2024.115893. PMID: 38657475
Shame in the treatment of patients with psychogenic nonepileptic seizures: The elephant in the room.
Myers L, Gray C, Roberts N, Levita L, Reuber M
Seizure 2022 Jan;94:176-182. Epub 2021 Oct 29 doi: 10.1016/j.seizure.2021.10.018. PMID: 34876339
Differences in the use of emotion regulation strategies between anorexia and bulimia nervosa: A systematic review and meta-analysis.
Puttevils L, Vanderhasselt MA, Horczak P, Vervaet M
Compr Psychiatry 2021 Aug;109:152262. Epub 2021 Jul 8 doi: 10.1016/j.comppsych.2021.152262. PMID: 34265598
Intrinsic functional connectivity during continuous maintenance and suppression of emotion in bipolar disorder.
Anand A, Grandhi J, Karne H, Spielberg JM
Brain Imaging Behav 2020 Oct;14(5):1747-1757. doi: 10.1007/s11682-019-00109-4. PMID: 31098939Free PMC Article
Altered emotion regulation in obsessive-compulsive disorder as evidenced by the late positive potential.
Paul S, Simon D, Endrass T, Kathmann N
Psychol Med 2016 Jan;46(1):137-47. Epub 2015 Sep 15 doi: 10.1017/S0033291715001610. PMID: 26370494

Therapy

Quantifying abnormal emotion processing: A novel computational assessment method and application in schizophrenia.
Bradley ER, Portanova J, Woolley JD, Buck B, Painter IS, Hankin M, Xu W, Cohen T
Psychiatry Res 2024 Jun;336:115893. Epub 2024 Apr 4 doi: 10.1016/j.psychres.2024.115893. PMID: 38657475
Neural basis of positive and negative emotion regulation in remitted depression.
van Kleef RS, Marsman JC, van Valen E, Bockting CLH, Aleman A, van Tol MJ
Neuroimage Clin 2022;34:102988. Epub 2022 Mar 11 doi: 10.1016/j.nicl.2022.102988. PMID: 35298997Free PMC Article
Inflammatory state and autism-like behavioral phenotype of offspring induced by maternal exposure to low-dose chemical mixtures during pregnancy in mice.
Song L, Wen W, Liu J, Jin X, Yang J
Zhejiang Da Xue Xue Bao Yi Xue Ban 2021 Jun 25;50(3):279-289. doi: 10.3724/zdxbyxb-2021-0182. PMID: 34402257Free PMC Article
Incapacity to control emotion in major depression may arise from disrupted white matter integrity and OFC-amygdala inhibition.
Zheng KZ, Wang HN, Liu J, Xi YB, Li L, Zhang X, Li JM, Yin H, Tan QR, Lu HB, Li BJ
CNS Neurosci Ther 2018 Nov;24(11):1053-1062. Epub 2018 Jan 24 doi: 10.1111/cns.12800. PMID: 29368421Free PMC Article
Cerebral Correlates of Abnormal Emotion Conflict Processing in Euthymic Bipolar Patients: A Functional MRI Study.
Favre P, Polosan M, Pichat C, Bougerol T, Baciu M
PLoS One 2015;10(8):e0134961. Epub 2015 Aug 5 doi: 10.1371/journal.pone.0134961. PMID: 26244883Free PMC Article

Clinical prediction guides

Abnormal global signal topography of self modulates emotion dysregulation in major depressive disorder.
Keskin K, Eker MÇ, Gönül AS, Northoff G
Transl Psychiatry 2023 Apr 3;13(1):107. doi: 10.1038/s41398-023-02398-2. PMID: 37012231Free PMC Article
Shame in the treatment of patients with psychogenic nonepileptic seizures: The elephant in the room.
Myers L, Gray C, Roberts N, Levita L, Reuber M
Seizure 2022 Jan;94:176-182. Epub 2021 Oct 29 doi: 10.1016/j.seizure.2021.10.018. PMID: 34876339
Moral processing deficit in behavioral variant frontotemporal dementia is associated with facial emotion recognition and brain changes in default mode and salience network areas.
Van den Stock J, Stam D, De Winter FL, Mantini D, Szmrecsanyi B, Van Laere K, Vandenberghe R, Vandenbulcke M
Brain Behav 2017 Dec;7(12):e00843. Epub 2017 Nov 29 doi: 10.1002/brb3.843. PMID: 29299378Free PMC Article
Neural processing of dynamic emotional facial expressions in psychopaths.
Decety J, Skelly L, Yoder KJ, Kiehl KA
Soc Neurosci 2014 Feb;9(1):36-49. doi: 10.1080/17470919.2013.866905. PMID: 24359488Free PMC Article
Impaired fronto-temporal processing of emotion in schizophrenia.
Bediou B, Hénaff MA, Bertrand O, Brunelin J, d'Amato T, Saoud M, Krolak-Salmon P
Neurophysiol Clin 2007 Apr-May;37(2):77-87. Epub 2007 Apr 13 doi: 10.1016/j.neucli.2007.04.001. PMID: 17540290

Recent systematic reviews

Differences in the use of emotion regulation strategies between anorexia and bulimia nervosa: A systematic review and meta-analysis.
Puttevils L, Vanderhasselt MA, Horczak P, Vervaet M
Compr Psychiatry 2021 Aug;109:152262. Epub 2021 Jul 8 doi: 10.1016/j.comppsych.2021.152262. PMID: 34265598
Neural correlates of dysfunctional emotion regulation in major depressive disorder. A systematic review of neuroimaging studies.
Rive MM, van Rooijen G, Veltman DJ, Phillips ML, Schene AH, Ruhé HG
Neurosci Biobehav Rev 2013 Dec;37(10 Pt 2):2529-53. Epub 2013 Aug 6 doi: 10.1016/j.neubiorev.2013.07.018. PMID: 23928089

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • ClinVar
      Related medical variations
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...