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Finger symphalangism

MedGen UID:
867041
Concept ID:
C4021399
Anatomical Abnormality
Synonym: Symphalangism in fingers
 
HPO: HP:0009700

Definition

An abnormal union between bones or parts of bones of the fingers. The synonymous term "symphalangism of the hand" may be translated as fusions of bones of varying digree, that involve at least one phalangeal bone of the hand. If bony fusions are referred to as "Symphalangism" the fusion occurs in a proximo-distal axis. Fusions of bones of the fingers in a radio-ulnar axis are referred to as "bony" Syndactyly. [from HPO]

Term Hierarchy

Conditions with this feature

Multiple synostoses syndrome 2
MedGen UID:
331348
Concept ID:
C1832708
Disease or Syndrome
Multiple synostoses syndrome-2 (SYNS2) is an autosomal dominant disorder characterized by progressive joint fusions of the fingers, wrists, ankles, and cervical spine; characteristic facies, including a broad hemicylindrical nose; and progressive conductive hearing loss (summary by Dawson et al., 2006). For a general phenotypic description and a discussion of genetic heterogeneity of multiple synostoses syndrome, see SYNS1 (186500).
Chromosome 17P13.3, telomeric, duplication syndrome
MedGen UID:
390813
Concept ID:
C2675492
Disease or Syndrome

Professional guidelines

PubMed

Askarian S, Gholami M, Khalili-Tanha G, Tehrani NC, Joudi M, Khazaei M, Ferns GA, Hassanian SM, Avan A, Joodi M
Oral Maxillofac Surg 2023 Jun;27(2):177-186. Epub 2022 Apr 15 doi: 10.1007/s10006-022-01052-3. PMID: 35426585
Woodside JC, Light TR
J Hand Surg Am 2016 Jan;41(1):135-43; quiz 143. Epub 2015 Aug 6 doi: 10.1016/j.jhsa.2015.06.114. PMID: 26254946
Baek GH, Lee HJ
Clin Orthop Surg 2012 Mar;4(1):58-65. Epub 2012 Feb 20 doi: 10.4055/cios.2012.4.1.58. PMID: 22379556Free PMC Article

Recent clinical studies

Therapy

Horiuchi S, Sato H, Iwasa A, Ichihara A, Tenshin H, Watanabe K, Hiasa M, Hashimoto I, Tanaka E
J Contemp Dent Pract 2021 Oct 1;22(10):1184-1190. PMID: 35197388
Park E, Bi A, King EC, Adkinson JM
Plast Reconstr Surg 2020 May;145(5):1215-1221. doi: 10.1097/PRS.0000000000006743. PMID: 32332541
Taylor HO, Gellis SE, Schmidt BA, Upton J, Rogers GF
Ann Plast Surg 2008 Oct;61(4):472-6. doi: 10.1097/SAP.0b013e31816d8236. PMID: 18812724
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Pfeiffer RA, Santelmann R
Birth Defects Orig Artic Ser 1977;13(1):319-37. PMID: 322750

Prognosis

Demetri LRF, Starcevich AG, Manske MCB, James MA
J Bone Joint Surg Am 2022 Jul 20;104(14):1301-1310. Epub 2022 Apr 14 doi: 10.2106/JBJS.21.01286. PMID: 35856931
Temtamy SA, Aglan MS
Orphanet J Rare Dis 2008 Jun 13;3:15. doi: 10.1186/1750-1172-3-15. PMID: 18554391Free PMC Article
Kapusta L, Brunner HG, Hamel BC
Eur J Pediatr 1992 Nov;151(11):837-41. doi: 10.1007/BF01957936. PMID: 1468459
Eaton CJ, Lister GD
Hand Clin 1990 Nov;6(4):555-75. PMID: 2176654
Colville J
Br J Plast Surg 1989 Jan;42(1):12-6. doi: 10.1016/s0007-1226(89)90106-9. PMID: 2537124

Clinical prediction guides

Park E, Bi A, King EC, Adkinson JM
Plast Reconstr Surg 2020 May;145(5):1215-1221. doi: 10.1097/PRS.0000000000006743. PMID: 32332541
Le Hanneur M, Cambon-Binder A, Bachy M, Fitoussi F
Hand Surg Rehabil 2020 May;39(3):143-153. Epub 2020 Mar 3 doi: 10.1016/j.hansur.2019.12.003. PMID: 32142954
Baek GH, Kim J
J Hand Surg Asian Pac Vol 2016 Oct;21(3):283-91. doi: 10.1142/S2424835516400087. PMID: 27595943
Kapusta L, Brunner HG, Hamel BC
Eur J Pediatr 1992 Nov;151(11):837-41. doi: 10.1007/BF01957936. PMID: 1468459
Ogino T
Hand Clin 1990 Nov;6(4):661-71. PMID: 2176655

Recent systematic reviews

Meyers A, Bassiri Gharb B, Rampazzo A
Plast Reconstr Surg 2023 Jun 1;151(6):1256-1273. Epub 2022 Dec 26 doi: 10.1097/PRS.0000000000010116. PMID: 36728793
Mende K, Watson A, Stewart DA
J Hand Surg Asian Pac Vol 2020 Mar;25(1):1-12. doi: 10.1142/S2424835520300017. PMID: 32000609
Bolea-Alamanac BM, Green A, Verma G, Maxwell P, Davies SJ
Br J Clin Pharmacol 2014 Jan;77(1):96-101. doi: 10.1111/bcp.12138. PMID: 23593966Free PMC Article

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