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Agenesis of lateral incisor

MedGen UID:
867502
•Concept ID:
C4021881
•
Anatomical Abnormality
Synonyms: Absence of lateral incisor; Failure of development of lateral incisor; Missing lateral incisor
 
HPO: HP:0200153

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAgenesis of lateral incisor

Conditions with this feature

Tooth agenesis, selective, X-linked, 1
MedGen UID:
410143
•Concept ID:
C1970757
•
Disease or Syndrome
Any tooth agenesis in which the cause of the disease is a mutation in the EDA gene.
See: Condition Record
Orofacial cleft 15
MedGen UID:
909661
•Concept ID:
C4225209
•
Congenital Abnormality
Any cleft lip/palate in which the cause of the disease is a mutation in the DLX4 gene.
See: Condition Record
Orofacial cleft 15
Tooth agenesis, selective, X-linked, 1

Professional guidelines

PubMed

Agenesis of maxillary lateral incisors: diagnosis and treatment options.
Schroeder DK, Schroeder MA, Vasconcelos V
Dental Press J Orthod 2022;27(1):e22spe1. Epub 2022 Jun 6 doi: 10.1590/2177-6709.27.1.e22spe1. PMID: 35674572Free PMC Article
Hypodontia: An Update on Its Etiology, Classification, and Clinical Management.
Al-Ani AH, Antoun JS, Thomson WM, Merriman TR, Farella M
Biomed Res Int 2017;2017:9378325. Epub 2017 Mar 19 doi: 10.1155/2017/9378325. PMID: 28401166Free PMC Article
Substitution treatment for missing lateral incisors.
Waldron JM
Am J Orthod Dentofacial Orthop 2004 Oct;126(4):21A-22A. doi: 10.1016/j.ajodo.2004.08.002. PMID: 15495375

Recent clinical studies

Etiology

The complex radicular groove: interdisciplinary management with mineral trioxide aggregate and bone substitute.
Narmatha VJ, Thakur S, Shetty S, Bali PK
J Contemp Dent Pract 2014 Nov 1;15(6):792-6. doi: 10.5005/jp-journals-10024-1620. PMID: 25825111
Bilateral fusion in primary mandibular teeth: a report of two cases.
Tewari N, Pandey RK
J Indian Soc Pedod Prev Dent 2011 Jan-Mar;29(1):50-2. doi: 10.4103/0970-4388.79936. PMID: 21521919
Class III malocclusion with missing maxillary lateral incisors.
Cozzani M, Lombardo L, Gracco A
Am J Orthod Dentofacial Orthop 2011 Mar;139(3):388-96. doi: 10.1016/j.ajodo.2009.09.022. PMID: 21392695
Oligodontia in Danish schoolchildren.
Rølling S, Poulsen S
Acta Odontol Scand 2001 Apr;59(2):111-2. doi: 10.1080/000163501750157298. PMID: 11370748
Prevalence of selected dental anomalies in Saudi children from Gizan region.
Salem G
Community Dent Oral Epidemiol 1989 Jun;17(3):162-3. doi: 10.1111/j.1600-0528.1989.tb00014.x. PMID: 2786794

Diagnosis

Agenesis of maxillary lateral incisors: diagnosis and treatment options.
Schroeder DK, Schroeder MA, Vasconcelos V
Dental Press J Orthod 2022;27(1):e22spe1. Epub 2022 Jun 6 doi: 10.1590/2177-6709.27.1.e22spe1. PMID: 35674572Free PMC Article
Untreated incomplete isolated cleft palate: cadaveric findings.
Kikuta S, Iwanaga J, Kusukawa J, Oskouian RJ, Tubbs RS, Shane Tubbs R
Anat Sci Int 2019 Jan;94(1):154-157. Epub 2018 Nov 30 doi: 10.1007/s12565-018-00471-1. PMID: 30506298
Supernumerary lateral incisor.
Kini A, Manjunatha M, Shubhashini N, Shija AS, Kumar VC, Jayashankar DN
J Contemp Dent Pract 2013 Jan 1;14(1):129-32. doi: 10.5005/jp-journals-10024-1285. PMID: 23579909
Talon cusp in the primary dentition: literature review and report of three rare cases.
Lee CK, King NM, Lo EC, Cho SY
J Clin Pediatr Dent 2006 Summer;30(4):299-305. doi: 10.17796/jcpd.30.4.1v1rk3053n018h84. PMID: 16937855
Managing congenitally missing lateral incisors. Part I: Canine substitution.
Kokich VO Jr, Kinzer GA
J Esthet Restor Dent 2005;17(1):5-10. doi: 10.1111/j.1708-8240.2005.tb00076.x. PMID: 15934680

Therapy

The complex radicular groove: interdisciplinary management with mineral trioxide aggregate and bone substitute.
Narmatha VJ, Thakur S, Shetty S, Bali PK
J Contemp Dent Pract 2014 Nov 1;15(6):792-6. doi: 10.5005/jp-journals-10024-1620. PMID: 25825111
Treatment of congenitally missing maxillary lateral incisors: an interdisciplinary approach.
Jackson BJ, Slavin MR
J Oral Implantol 2013 Apr;39(2):187-92. doi: 10.1563/AAID-JOI-D-12-00025. PMID: 23611678
Facial cellulitis secondary to dens invaginatus: a case report.
Arsenault M, Anderson RD, Dyment H, MacLellan J, Doyle T
J Can Dent Assoc 2010;76:a114. PMID: 20943029
Endodontic treatment of immature tooth with dens invaginatus: a case report.
Tarján I, Rózsa N
Int J Paediatr Dent 1999 Mar;9(1):53-6. doi: 10.1046/j.1365-263x.1999.00100.x. PMID: 10336718
Talon cusp in Malaysia.
Rusmah, Meon
Aust Dent J 1991 Feb;36(1):11-4. doi: 10.1111/j.1834-7819.1991.tb00801.x. PMID: 2029226

Prognosis

Hypodontia: An Update on Its Etiology, Classification, and Clinical Management.
Al-Ani AH, Antoun JS, Thomson WM, Merriman TR, Farella M
Biomed Res Int 2017;2017:9378325. Epub 2017 Mar 19 doi: 10.1155/2017/9378325. PMID: 28401166Free PMC Article
The complex radicular groove: interdisciplinary management with mineral trioxide aggregate and bone substitute.
Narmatha VJ, Thakur S, Shetty S, Bali PK
J Contemp Dent Pract 2014 Nov 1;15(6):792-6. doi: 10.5005/jp-journals-10024-1620. PMID: 25825111
Palatogingival groove: endodontic-periodontal management--case report.
Attam K, Tiwary R, Talwar S, Lamba AK
J Endod 2010 Oct;36(10):1717-20. Epub 2010 Aug 17 doi: 10.1016/j.joen.2010.06.025. PMID: 20850685
Managing congenitally missing lateral incisors. Part I: Canine substitution.
Kokich VO Jr, Kinzer GA
J Esthet Restor Dent 2005;17(1):5-10. doi: 10.1111/j.1708-8240.2005.tb00076.x. PMID: 15934680
Talon cusp in Malaysia.
Rusmah, Meon
Aust Dent J 1991 Feb;36(1):11-4. doi: 10.1111/j.1834-7819.1991.tb00801.x. PMID: 2029226

Clinical prediction guides

Hypodontia: An Update on Its Etiology, Classification, and Clinical Management.
Al-Ani AH, Antoun JS, Thomson WM, Merriman TR, Farella M
Biomed Res Int 2017;2017:9378325. Epub 2017 Mar 19 doi: 10.1155/2017/9378325. PMID: 28401166Free PMC Article
Treatment of congenitally missing maxillary lateral incisors: an interdisciplinary approach.
Jackson BJ, Slavin MR
J Oral Implantol 2013 Apr;39(2):187-92. doi: 10.1563/AAID-JOI-D-12-00025. PMID: 23611678
Talon cusp: a case series.
Peker I, Alkurt MT
Gen Dent 2009 Sep-Oct;57(5):524-7. PMID: 19903646
Managing congenitally missing lateral incisors. Part I: Canine substitution.
Kokich VO Jr, Kinzer GA
J Esthet Restor Dent 2005;17(1):5-10. doi: 10.1111/j.1708-8240.2005.tb00076.x. PMID: 15934680
Talon cusp in Malaysia.
Rusmah, Meon
Aust Dent J 1991 Feb;36(1):11-4. doi: 10.1111/j.1834-7819.1991.tb00801.x. PMID: 2029226

Recent systematic reviews

Association between superior labial frenum and maxillary midline diastema - a systematic review.
Tadros S, Ben-Dov T, Catháin ÉÓ, Anglin C, April MM
Int J Pediatr Otorhinolaryngol 2022 May;156:111063. Epub 2022 Feb 26 doi: 10.1016/j.ijporl.2022.111063. PMID: 35248905
Impacted and transmigrant mandibular canines incidence, aetiology, and treatment: a systematic review.
Dalessandri D, Parrini S, Rubiano R, Gallone D, Migliorati M
Eur J Orthod 2017 Apr 1;39(2):161-169. doi: 10.1093/ejo/cjw027. PMID: 27036134
Prosthetic replacement vs space closure for maxillary lateral incisor agenesis: A systematic review.
Silveira GS, de Almeida NV, Pereira DM, Mattos CT, Mucha JN
Am J Orthod Dentofacial Orthop 2016 Aug;150(2):228-37. doi: 10.1016/j.ajodo.2016.01.018. PMID: 27476355
Prevalence of hypodontia and associated factors: a systematic review and meta-analysis.
Khalaf K, Miskelly J, Voge E, Macfarlane TV
J Orthod 2014 Dec;41(4):299-316. doi: 10.1179/1465313314Y.0000000116. PMID: 25404667
Treatment for agenesis of maxillary lateral incisors: a systematic review.
Andrade DC, Loureiro CA, Araújo VE, Riera R, Atallah AN
Orthod Craniofac Res 2013 Aug;16(3):129-36. Epub 2013 Feb 14 doi: 10.1111/ocr.12015. PMID: 23406509

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