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Abnormal nasal base norphology

MedGen UID:
868324
•Concept ID:
C4022718
•
Anatomical Abnormality
Synonyms: Abnormal nasal base; Abnormality of base of nose; Anomaly of base of nose; Anomaly of nasal base; Deformity of base of nose; Deformity of nasal base; Malformation of base of nose; Malformation of nasal base
 
HPO: HP:0012808

Definition

An anomaly of the nasal base, which can be conceived of as an imaginary line between the most lateral points of the external inferior attachments of the alae nasi to the face. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal nasal base norphology

Professional guidelines

PubMed

Practical multidisciplinary framework for the assessment and management of patients with unexplained chronic aerodigestive symptoms.
Quigley N, Mistry SG, Vasant DH, Vasani S
BMJ Open Gastroenterol 2023 Nov 23;10(1) doi: 10.1136/bmjgast-2022-000883. PMID: 37996120Free PMC Article
Smell and Taste Disorders in Primary Care.
Savard DJ, Ursua FG, Gaddey HL
Am Fam Physician 2023 Sep;108(3):240-248. PMID: 37725455
Nasal encephaloceles: a review of etiology, pathophysiology, clinical presentations, diagnosis, treatment, and complications.
Tirumandas M, Sharma A, Gbenimacho I, Shoja MM, Tubbs RS, Oakes WJ, Loukas M
Childs Nerv Syst 2013 May;29(5):739-44. Epub 2012 Dec 18 doi: 10.1007/s00381-012-1998-z. PMID: 23247827

Recent clinical studies

Etiology

Post-viral effects of COVID-19 in the olfactory system and their implications.
Xydakis MS, Albers MW, Holbrook EH, Lyon DM, Shih RY, Frasnelli JA, Pagenstecher A, Kupke A, Enquist LW, Perlman S
Lancet Neurol 2021 Sep;20(9):753-761. Epub 2021 Jul 30 doi: 10.1016/S1474-4422(21)00182-4. PMID: 34339626Free PMC Article
Airway Analysis in Apert Syndrome.
Forte AJ, Lu X, Hashim PW, Steinbacher DM, Alperovich M, Persing JA, Alonso N
Plast Reconstr Surg 2019 Sep;144(3):704-709. doi: 10.1097/PRS.0000000000005937. PMID: 31461034
Innovations in Endonasal Sinus Surgery in Children.
Shay SG, Valika T, Chun R, Rastatter J
Otolaryngol Clin North Am 2019 Oct;52(5):875-890. Epub 2019 Jul 26 doi: 10.1016/j.otc.2019.06.003. PMID: 31353137
Choanal Atresia and Other Neonatal Nasal Anomalies.
Rajan R, Tunkel DE
Clin Perinatol 2018 Dec;45(4):751-767. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.011. PMID: 30396416
Advanced airway management strategies for severe OSAS and craniofacial anomalies.
Gungor A
Am J Otolaryngol 2017 Jan-Feb;38(1):77-81. Epub 2016 Sep 28 doi: 10.1016/j.amjoto.2016.09.016. PMID: 27756487

Diagnosis

Imaging of Developmental Skull Base Abnormalities.
Siddiqui A, Connor SEJ
Neuroimaging Clin N Am 2021 Nov;31(4):621-647. doi: 10.1016/j.nic.2021.06.004. PMID: 34689936
Raine syndrome: an overview.
Faundes V, Castillo-Taucher S, Gonzalez-Hormazabal P, Chandler K, Crosby A, Chioza B
Eur J Med Genet 2014 Sep;57(9):536-42. Epub 2014 Jul 12 doi: 10.1016/j.ejmg.2014.07.001. PMID: 25019372
The olfactory system.
Leboucq N, Menjot de Champfleur N, Menjot de Champfleur S, Bonafé A
Diagn Interv Imaging 2013 Oct;94(10):985-91. Epub 2013 Aug 7 doi: 10.1016/j.diii.2013.06.006. PMID: 23932763
Gustatory rhinitis.
Georgalas C, Jovancevic L
Curr Opin Otolaryngol Head Neck Surg 2012 Feb;20(1):9-14. doi: 10.1097/MOO.0b013e32834dfb52. PMID: 22143339
Johanson-Blizzard syndrome.
Almashraki N, Abdulnabee MZ, Sukalo M, Alrajoudi A, Sharafadeen I, Zenker M
World J Gastroenterol 2011 Oct 7;17(37):4247-50. doi: 10.3748/wjg.v17.i37.4247. PMID: 22072859Free PMC Article

Therapy

Rhinoplasty in Patients with Cleft Lip Nasal Deformity: Correcting the Alar Base.
DeVictor SR, Tollefson TT
Facial Plast Surg 2023 Dec;39(6):668-673. Epub 2023 Jul 11 doi: 10.1055/a-2127-3665. PMID: 37433309
Management of Frontal Sinus Cerebrospinal Fluid Leaks and Encephaloceles.
Illing EA, Woodworth BA
Otolaryngol Clin North Am 2016 Aug;49(4):1035-50. doi: 10.1016/j.otc.2016.03.025. PMID: 27450619
Gustatory rhinitis.
Georgalas C, Jovancevic L
Curr Opin Otolaryngol Head Neck Surg 2012 Feb;20(1):9-14. doi: 10.1097/MOO.0b013e32834dfb52. PMID: 22143339
Lip repair techniques and their influence on the nose.
Farmand M
Facial Plast Surg 2002 Aug;18(3):155-64. doi: 10.1055/s-2002-33062. PMID: 12152134
Alar rim deformities.
Guyuron B
Plast Reconstr Surg 2001 Mar;107(3):856-63. doi: 10.1097/00006534-200103000-00032. PMID: 11304615

Prognosis

Post-viral effects of COVID-19 in the olfactory system and their implications.
Xydakis MS, Albers MW, Holbrook EH, Lyon DM, Shih RY, Frasnelli JA, Pagenstecher A, Kupke A, Enquist LW, Perlman S
Lancet Neurol 2021 Sep;20(9):753-761. Epub 2021 Jul 30 doi: 10.1016/S1474-4422(21)00182-4. PMID: 34339626Free PMC Article
Choanal Atresia and Other Neonatal Nasal Anomalies.
Rajan R, Tunkel DE
Clin Perinatol 2018 Dec;45(4):751-767. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.011. PMID: 30396416
Advanced airway management strategies for severe OSAS and craniofacial anomalies.
Gungor A
Am J Otolaryngol 2017 Jan-Feb;38(1):77-81. Epub 2016 Sep 28 doi: 10.1016/j.amjoto.2016.09.016. PMID: 27756487
Endoscopic Endonasal Management of Orbital Pathologies.
Castelnuovo P, Turri-Zanoni M, Battaglia P, Locatelli D, Dallan I
Neurosurg Clin N Am 2015 Jul;26(3):463-72. Epub 2015 May 7 doi: 10.1016/j.nec.2015.03.001. PMID: 26141364
Raine syndrome: an overview.
Faundes V, Castillo-Taucher S, Gonzalez-Hormazabal P, Chandler K, Crosby A, Chioza B
Eur J Med Genet 2014 Sep;57(9):536-42. Epub 2014 Jul 12 doi: 10.1016/j.ejmg.2014.07.001. PMID: 25019372

Clinical prediction guides

Lip-Shortening Surgery.
Gatti JE
Plast Reconstr Surg 2023 Oct 1;152(4):765-772. Epub 2023 Mar 7 doi: 10.1097/PRS.0000000000010361. PMID: 36877617
Cranial Pair 0: The Nervus Terminalis.
Peña-Melián Á, Cabello-de la Rosa JP, Gallardo-Alcañiz MJ, Vaamonde-Gamo J, Relea-Calatayud F, González-López L, Villanueva-Anguita P, Flores-Cuadrado A, Saiz-Sánchez D, Martínez-Marcos A
Anat Rec (Hoboken) 2019 Mar;302(3):394-404. Epub 2018 May 17 doi: 10.1002/ar.23826. PMID: 29663690
Johanson-Blizzard syndrome.
Almashraki N, Abdulnabee MZ, Sukalo M, Alrajoudi A, Sharafadeen I, Zenker M
World J Gastroenterol 2011 Oct 7;17(37):4247-50. doi: 10.3748/wjg.v17.i37.4247. PMID: 22072859Free PMC Article
Development of the facial midline.
Carstens MH
J Craniofac Surg 2002 Jan;13(1):129-87; discussion 188-90. doi: 10.1097/00001665-200201000-00032. PMID: 11887012
Alar rim deformities.
Guyuron B
Plast Reconstr Surg 2001 Mar;107(3):856-63. doi: 10.1097/00006534-200103000-00032. PMID: 11304615

Recent systematic reviews

Congenital trans-sellar trans-sphenoidal encephalocele: a systematic review of diagnosis, treatment, and prognosis.
Jiang Z, Yang D, Ainiwaer M, Li Q, Mo W, Liu F
Eur Arch Otorhinolaryngol 2024 Apr;281(4):1659-1670. Epub 2024 Jan 8 doi: 10.1007/s00405-023-08355-5. PMID: 38189965Free PMC Article
Systematic Review and Critical Appraisal of the Evidence Base for Nasoalveolar Molding (NAM).
Dunworth K, Porras Fimbres D, Trotta R, Hollins A, Shammas R, Allori AC, Santiago PE
Cleft Palate Craniofac J 2024 Apr;61(4):654-677. Epub 2022 Nov 4 doi: 10.1177/10556656221136325. PMID: 36330703
Empty Nose Syndrome Pathophysiology: A Systematic Review.
Kanjanawasee D, Campbell RG, Rimmer J, Alvarado R, Kanjanaumporn J, Snidvongs K, Kalish L, Harvey RJ, Sacks R
Otolaryngol Head Neck Surg 2022 Sep;167(3):434-451. Epub 2021 Oct 19 doi: 10.1177/01945998211052919. PMID: 34665687
Pediatric rhinoplasty: A discussion of perioperative considerations and systematic review.
Gupta A, Svider PF, Rayess H, Sheyn A, Folbe AJ, Eloy JA, Zuliani G, Carron MA
Int J Pediatr Otorhinolaryngol 2017 Jan;92:11-16. Epub 2016 Oct 26 doi: 10.1016/j.ijporl.2016.10.027. PMID: 28012510
A systematic review of the oral and craniofacial manifestations of cri du chat syndrome.
Corcuera-Flores JR, Casttellanos-Cosano L, Torres-Lagares D, Serrera-Figallo MÁ, Rodríguez-Caballero Á, Machuca-Portillo G
Clin Anat 2016 Jul;29(5):555-60. Epub 2015 Dec 21 doi: 10.1002/ca.22654. PMID: 26457586

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