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Reduced circulating catalase activity

MedGen UID:
868475
•Concept ID:
C4022869
•
Finding
Synonym: Reduced catalase activity
 
HPO: HP:0012517

Definition

Activity or concentration of catalase in the blood circulation below the lower limit of normal. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVReduced circulating catalase activity

Conditions with this feature

Acatalasia
MedGen UID:
75679
•Concept ID:
C0268419
•
Disease or Syndrome
Acatalasemia, also known as acatalasia, is a metabolic disorder characterized by a total or near total loss of catalase activity in erythrocytes. About half of cases originate from ulcerating oral gangrenes, and these cases are referred to as having Takahara disease. Half-normal levels of catalase in heterozygotes is referred to as hypocatalasemia or hypocatalasia (Ogata, 1991).
See: Condition Record
Acatalasia

Professional guidelines

PubMed

Effect of recombinant human IFNγ in the treatment of chronic pulmonary complications due to sulfur mustard intoxication.
Panahi Y, Ghanei M, Vahedi E, Ghazvini A, Parvin S, Madanchi N, Bagheri M, Sahebkar A
J Immunotoxicol 2014 Jan-Mar;11(1):72-7. Epub 2013 Jun 14 doi: 10.3109/1547691X.2013.797525. PMID: 23768082
Viper venom-induced oxidative stress and activation of inflammatory cytokines: a therapeutic approach for overlooked issues of snakebite management.
Santhosh MS, Sundaram MS, Sunitha K, Kemparaju K, Girish KS
Inflamm Res 2013 Jul;62(7):721-31. Epub 2013 May 9 doi: 10.1007/s00011-013-0627-y. PMID: 23657249
Pyridoxalated hemoglobin polyoxyethylene: a nitric oxide scavenger with antioxidant activity for the treatment of nitric oxide-induced shock.
Privalle C, Talarico T, Keng T, DeAngelo J
Free Radic Biol Med 2000 May 15;28(10):1507-17. doi: 10.1016/s0891-5849(00)00260-4. PMID: 10927175

Recent clinical studies

Etiology

Diagnostic significance and utility of circulating redox biomarkers in patients with gastric cancer - preliminary study.
Dorf J, Zaręba K, Pryczynicz A, Matowicka-Karna J, Kędra B, Żukowski P, Zalewska A, Maciejczyk M
Ann Med 2023;55(2):2241472. doi: 10.1080/07853890.2023.2241472. PMID: 37506191Free PMC Article
Zinc improves sexual performance and erectile function by preventing penile oxidative injury and upregulating circulating testosterone in lead-exposed rats.
Besong EE, Akhigbe TM, Ashonibare PJ, Oladipo AA, Obimma JN, Hamed MA, Adeyemi DH, Akhigbe RE
Redox Rep 2023 Dec;28(1):2225675. doi: 10.1080/13510002.2023.2225675. PMID: 37345699Free PMC Article
Protective effects of long-term nitrate administration against ovariectomy-induced kidney dysfunction in rats.
Yousefzadeh N, Jeddi S, Zarkesh M, Norouzirad R, Kashfi K, Ghasemi A
Pharmacol Rep 2023 Aug;75(4):979-994. Epub 2023 Jun 1 doi: 10.1007/s43440-023-00499-9. PMID: 37258800
Oxidative damage and antioxidants in cervical cancer.
Preci DP, Almeida A, Weiler AL, Mukai Franciosi ML, Cardoso AM
Int J Gynecol Cancer 2021 Feb;31(2):265-271. Epub 2020 Oct 27 doi: 10.1136/ijgc-2020-001587. PMID: 33109527
A Mini-Review on the Effect of Docosahexaenoic Acid (DHA) on Cerulein-Induced and Hypertriglyceridemic Acute Pancreatitis.
Jeong YK, Kim H
Int J Mol Sci 2017 Oct 25;18(11) doi: 10.3390/ijms18112239. PMID: 29068376Free PMC Article

Diagnosis

Diagnostic significance and utility of circulating redox biomarkers in patients with gastric cancer - preliminary study.
Dorf J, Zaręba K, Pryczynicz A, Matowicka-Karna J, Kędra B, Żukowski P, Zalewska A, Maciejczyk M
Ann Med 2023;55(2):2241472. doi: 10.1080/07853890.2023.2241472. PMID: 37506191Free PMC Article
Changes in Peripheral Blood Biomarkers with Aging and Neurodegenerative Disorders.
Lima M, Pestana C
Curr Aging Sci 2021;14(2):112-117. doi: 10.2174/1874609814666210127090100. PMID: 33504320
Chimarrão consumption and prognostic factors in breast cancer: Correlation with antioxidants and blood caffeine levels.
Calixto MRP, Rech D, Dos Santos VL, Madeira TB, Nixdorf SL, Fagundes TR, Davis RAH, Bastos FF, Bastos-Neto JDC, Bastos VLFDC, Zanandrea AC, de Lima JR, Victorino VJ, Panis C
Phytother Res 2021 Feb;35(2):888-897. Epub 2020 Sep 14 doi: 10.1002/ptr.6836. PMID: 32924205
Development of albuminuria and enhancement of oxidative stress during chronic renin-angiotensin system suppression.
Ruiz-Hurtado G, Condezo-Hoyos L, Pulido-Olmo H, Aranguez I, Del Carmen Gónzalez M, Arribas S, Cerezo C, Segura J, Praga M, Fernández-Alfonso MS, Ruilope LM
J Hypertens 2014 Oct;32(10):2082-91; discussion 2091. doi: 10.1097/HJH.0000000000000292. PMID: 25033166
Chemistry and antihypertensive effects of tempol and other nitroxides.
Wilcox CS, Pearlman A
Pharmacol Rev 2008 Dec;60(4):418-69. doi: 10.1124/pr.108.000240. PMID: 19112152Free PMC Article

Therapy

Zinc improves sexual performance and erectile function by preventing penile oxidative injury and upregulating circulating testosterone in lead-exposed rats.
Besong EE, Akhigbe TM, Ashonibare PJ, Oladipo AA, Obimma JN, Hamed MA, Adeyemi DH, Akhigbe RE
Redox Rep 2023 Dec;28(1):2225675. doi: 10.1080/13510002.2023.2225675. PMID: 37345699Free PMC Article
A Mini-Review on the Effect of Docosahexaenoic Acid (DHA) on Cerulein-Induced and Hypertriglyceridemic Acute Pancreatitis.
Jeong YK, Kim H
Int J Mol Sci 2017 Oct 25;18(11) doi: 10.3390/ijms18112239. PMID: 29068376Free PMC Article
Oxidative stress in IgA nephropathy.
Coppo R, Camilla R, Amore A, Peruzzi L
Nephron Clin Pract 2010;116(3):c196-8, discussion c199. Epub 2010 Jul 2 doi: 10.1159/000317199. PMID: 20606479
Inhibition of metastatic tumor growth by targeted delivery of antioxidant enzymes.
Nishikawa M, Hyoudou K, Kobayashi Y, Umeyama Y, Takakura Y, Hashida M
J Control Release 2005 Dec 5;109(1-3):101-7. Epub 2005 Oct 26 doi: 10.1016/j.jconrel.2005.09.017. PMID: 16256238
The antioxidant effects of statins.
Davignon J, Jacob RF, Mason RP
Coron Artery Dis 2004 Aug;15(5):251-8. doi: 10.1097/01.mca.0000131573.31966.34. PMID: 15238821

Prognosis

General Rehabilitation Program after Knee or Hip Replacement Significantly Influences Erythrocytes Oxidative Stress Markers and Serum ST2 Levels.
Idzik M, Poloczek J, Skrzep-Poloczek B, Chełmecka E, Jochem J, Stygar D
Oxid Med Cell Longev 2022;2022:1358858. Epub 2022 Mar 30 doi: 10.1155/2022/1358858. PMID: 35401921Free PMC Article
Oxidative damage and antioxidants in cervical cancer.
Preci DP, Almeida A, Weiler AL, Mukai Franciosi ML, Cardoso AM
Int J Gynecol Cancer 2021 Feb;31(2):265-271. Epub 2020 Oct 27 doi: 10.1136/ijgc-2020-001587. PMID: 33109527
Chimarrão consumption and prognostic factors in breast cancer: Correlation with antioxidants and blood caffeine levels.
Calixto MRP, Rech D, Dos Santos VL, Madeira TB, Nixdorf SL, Fagundes TR, Davis RAH, Bastos FF, Bastos-Neto JDC, Bastos VLFDC, Zanandrea AC, de Lima JR, Victorino VJ, Panis C
Phytother Res 2021 Feb;35(2):888-897. Epub 2020 Sep 14 doi: 10.1002/ptr.6836. PMID: 32924205
Evidence for a hyper-reductive redox in a sub-set of heart failure patients.
Sairam T, Patel AN, Subrahmanian M, Gopalan R, Pogwizd SM, Ramalingam S, Sankaran R, Rajasekaran NS
J Transl Med 2018 May 18;16(1):130. doi: 10.1186/s12967-018-1503-x. PMID: 29776421Free PMC Article
Significance of Lipid-Derived Reactive Aldehyde-Specific Immune Complexes in Systemic Lupus Erythematosus.
Wang G, Pierangeli SS, Willis R, Gonzalez EB, Petri M, Khan MF
PLoS One 2016;11(10):e0164739. Epub 2016 Oct 17 doi: 10.1371/journal.pone.0164739. PMID: 27749917Free PMC Article

Clinical prediction guides

Metabolomic, oxidative, and inflammatory responses to acute exercise in chronic obstructive pulmonary disease.
Cakmak A, Nemutlu E, Yabanoglu-Ciftci S, Baysal I, Kocaaga E, Coplu L, Inal-Ince D
Heart Lung 2023 May-Jun;59:52-60. Epub 2023 Jan 30 doi: 10.1016/j.hrtlng.2023.01.011. PMID: 36724589
Ketone bodies mimic the life span extending properties of caloric restriction.
Veech RL, Bradshaw PC, Clarke K, Curtis W, Pawlosky R, King MT
IUBMB Life 2017 May;69(5):305-314. Epub 2017 Apr 3 doi: 10.1002/iub.1627. PMID: 28371201
Significance of Lipid-Derived Reactive Aldehyde-Specific Immune Complexes in Systemic Lupus Erythematosus.
Wang G, Pierangeli SS, Willis R, Gonzalez EB, Petri M, Khan MF
PLoS One 2016;11(10):e0164739. Epub 2016 Oct 17 doi: 10.1371/journal.pone.0164739. PMID: 27749917Free PMC Article
Amorphous silica nanoparticles impair vascular homeostasis and induce systemic inflammation.
Nemmar A, Albarwani S, Beegam S, Yuvaraju P, Yasin J, Attoub S, Ali BH
Int J Nanomedicine 2014;9:2779-89. Epub 2014 Jun 2 doi: 10.2147/IJN.S52818. PMID: 24936130Free PMC Article
Deleterious effects of oxygen radicals in ischemia/reperfusion. Resolved and unresolved issues.
Kloner RA, Przyklenk K, Whittaker P
Circulation 1989 Nov;80(5):1115-27. doi: 10.1161/01.cir.80.5.1115. PMID: 2553296

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